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1.
Article in English | MEDLINE | ID: mdl-38848950

ABSTRACT

INTRODUCTION: The Werther, Copycat or contagion effect of suicidal behaviour is a complex phenomenon that can arise due to exposure to media stories in which identifiable people take their lives. On the contrary, the Papageno effect prevents people from suicide by promoting positives examples of suicidal crisis management. Impact of both effects has been widely studied in different types of situations, but its existence in social media is a source of much debate. METHODS: A systematic search following the PRISMA guidelines of PubMed, Scopus, Embase, PsycInfo, Web of Science and the references of prior reviews yielded 25 eligible studies. RESULTS: Most of the studies found were observational, with very different methodologies and generally with low risk of bias. In these, the results suggest the existence of the Werther effect in response to social media stories about suicide. This is mediated by multiple factors, including the characteristic of the users, the type of interaction and the content of the publications. At the same time, the Papageno effect is also described. Evidence found by type of social media and future implications are discussed. CONCLUSION: Suicidal content on social media can be both contagious and protective. It is confirmed that the Werther and Papageno effects may occur in response to social media, so they could be an interesting target for preventive interventions.

3.
Am J Forensic Med Pathol ; 45(2): 151-156, 2024 Jun 01.
Article in English | MEDLINE | ID: mdl-38739896

ABSTRACT

ABSTRACT: Autopsy followed by histopathological examination is foundational in clinical and forensic medicine for discovering and understanding pathological changes in disease, their underlying processes, and cause of death. Imaging technology has become increasingly important for advancing clinical research and practice, given its noninvasive, in vivo and ex vivo applicability. Medical and forensic autopsy can benefit greatly from advances in imaging technology that lead toward minimally invasive, whole-brain virtual autopsy. Brain autopsy followed by histopathological examination is still the hallmark for understanding disease and a fundamental modus operandi in forensic pathology and forensic medicine, despite the fact that its practice has become progressively less frequent in medical settings. This situation is especially relevant with respect to new diseases such as COVID-19 caused by the SARS-CoV-2 virus, for which our neuroanatomical knowledge is sparse. In this narrative review, we show that ad hoc clinical autopsies and histopathological analyses combined with neuroimaging of the principal circumventricular organs are critical to gaining insight into the reconstruction of the pathophysiological mechanisms and the explanation of cause of death (ie, atrium mortis) related to the cardiovascular effects of SARS-CoV-2 infection in forensic and clinical medicine.


Subject(s)
COVID-19 , Humans , COVID-19/pathology , COVID-19/diagnostic imaging , Neuroimaging/methods , Autopsy/methods , Brain/pathology , Brain/diagnostic imaging , SARS-CoV-2 , Forensic Pathology/methods , Clinical Relevance
4.
Animals (Basel) ; 14(8)2024 Apr 18.
Article in English | MEDLINE | ID: mdl-38672363

ABSTRACT

The objective of this study was to evaluate the effects of increasing levels of the M-E complex (xylanase, glucanase, cellulase, and invertase) Optimax E® on the performance of growing lambs, their digestibility, and their rumen microbiota, and to estimate NEm, NEg, and ruminal methane levels. Forty lambs (Katahdin x Dorset; 22.91 ± 4.16 kg) were randomly assigned to dietary concentrations of ME (0, 0.2, 0.4, and 0.8% DM) and fed individually for 77 days. Increasing M-E improved feed conversion (p < 0.05) as well as NEm and NEg (p < 0.05), which were associated with increased in vivo DM and NDF digestion (linear and quadratic p < 0.01). Few microbial families showed abundancy changes (Erysipelotrichaceae, Christensenellaceae, Lentisphaerae, and Clostridial Family XIII); however, the dominant phylum Bacteroidetes was linearly reduced, while Firmicutes increased (p < 0.01), resulting in a greater Firmicutes-to-Bacteroidetes ratio. Total Entodinium showed a quadratic response (p < 0.10), increasing its abundancy as the enzyme dose was augmented. The daily emission intensity of methane (per kg of DMI or AGD) was reduced linearly (p < 0.01). In conclusion, adding the M-E complex Optimax E® to growing lambs' diets improves their productive performance by acting synergistically with the rumen microbiota, modifying the Firmicutes-to-Bacteroidetes ratio toward more efficient fermentation, and shows the potential to reduce the intensity of greenhouse gas emissions from lambs.

5.
Haemophilia ; 30(3): 791-799, 2024 May.
Article in English | MEDLINE | ID: mdl-38470981

ABSTRACT

INTRODUCTION: Activity wristbands have been shown to be effective in relation to self-monitoring activity levels and increasing exercise adherence. However, previous reports have been based on short-term follow-ups in people with haemophilia (PWH). AIM: (1) To evaluate compliance with physical activity (PA) recommendations in PWH during a 1-year follow-up period using activity wristbands to record daily steps and intensity; (2) To determine the effect of PA self-monitoring on clinical outcomes. METHODS: A prospective observational study was conducted in 27 adults with severe haemophilia undergoing prophylactic treatment. The Fitbit Charge HR was used to track daily PA for an entire year. The participants were encouraged to try to reach a goal of 10,000 steps/day and to track their progress. The pre- and post-evaluation included quality of life (A36 Hemophilia-QoL Questionnaire), joint health (Haemophilia Joint Health Score), functionality (Timed Up and Go test), and muscle strength. RESULTS: A total of 323.63 (95%CI: 194-364) valid days (i.e., > 2000 steps) were recorded. The annual average number of steps per day taken by participants was 10,379. Sixteen (59%) PWH reached 10,000 steps/day at baseline and 17 (63%) at 1 year follow-up, with no significant differences (x2 = .33; p = .56). A statistically significant improvement was observed in daily moderate activity time (p = .012) and in the 'physical health' quality of life subscale (mean difference: 2.15 points; 95%CI: .64-3.65; p = .007). CONCLUSION: Our results suggest that patients with severe haemophilia who self-managed their PA can improve their long-term quality of life in the domain of physical health and also the daily time spent in moderate-intensity PA.


Subject(s)
Exercise , Hemophilia A , Quality of Life , Humans , Hemophilia A/therapy , Prospective Studies , Adult , Male , Follow-Up Studies , Female , Young Adult , Middle Aged , Surveys and Questionnaires
6.
Actas Esp Psiquiatr ; 52(1): 57-59, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38454894

ABSTRACT

Antibiomanic episodes, or as the DSM-5 refers to them, drug-induced manic episodes, pose a clinical challenge that is still poorly understood. There is insufficient information on the most common clinical presentation, patient profile, or underlying aetiopathogenic mechanisms. We present the clinical case of a 67-year-old woman who, after starting treatment (clarithromycin and amoxicillin) for the eradication of Helicobacter pylori, bacteria presented with a brief manic episode, which resolved after withdrawal of both drugs and with antipsychotic treatment. The possible interaction of both drugs, as GABA antagonists, in the generation of such episodes is discussed, and the clinical importance of such episodes in psychiatric emergency departments and liaison and interconsultation psychiatry, is highlighted.


Subject(s)
Helicobacter Infections , Helicobacter pylori , Aged , Female , Humans , Amoxicillin/adverse effects , Anti-Bacterial Agents/adverse effects , Clarithromycin/adverse effects , Drug Therapy, Combination , Helicobacter Infections/drug therapy , Helicobacter Infections/microbiology , Mania/drug therapy , Treatment Outcome
7.
Zootaxa ; 5415(3): 401-435, 2024 Feb 22.
Article in English | MEDLINE | ID: mdl-38480194

ABSTRACT

The Neotropical genus Piezonemus Jordan, 1904 (Anthribidae: Anthribinae: Piesocorynini Valentine, 1960) is reviewed. Lectotypes are designated for Piezonemus durus Jordan, 1904 and P. lateralis Jordan, 1904. A new species, Piezonemus espoch Trzna, Caballero-Serrano & Carrasco sp. nov., from Ecuador is described. A key to the now three known species of Piezonemus, and colour photographs of the types, are provided. Distinguishing features of the morphologically similar species of the genera Piezonemus and Piesocorynus Dejean, 1834 are given. A key to world genera of the tribe Piesocorynini is presented. The genus Afrophaenotherion Frieser, 1984 is here transferred from the tribe Stenocerini Kolbe, 1895 to the tribe Piesocorynini (new placement).


Subject(s)
Coleoptera , Animals , Jordan , Ecuador
8.
Biomedicines ; 12(2)2024 Jan 23.
Article in English | MEDLINE | ID: mdl-38397861

ABSTRACT

Intussusceptive angiogenesis (IA) and intussusceptive lymphangiogenesis (IL) play a key role in the growth and morphogenesis of vessels. However, there are very few studies in this regard in vessel tumors (VTs). Our objective is to assess the presence, characteristics, and possible mechanisms of the formation of intussusceptive structures in a broad spectrum of VTs. For this purpose, examples of benign and malignant blood and lymphatic VTs were studied via conventional procedures, semithin sections, and immunochemistry and immunofluorescence microscopy. The results demonstrated intussusceptive structures (pillars, meshes, and folds) in benign (lobular capillary hemangioma or pyogenic granuloma, intravascular papillary endothelial hyperplasia or Masson tumor, sinusoidal hemangioma, cavernous hemangioma, glomeruloid hemangioma, angiolipoma, and lymphangiomas), low-grade malignancy (retiform hemangioendothelioma and Dabska tumor), and malignant (angiosarcoma and Kaposi sarcoma) VTs. Intussusceptive structures showed an endothelial cover and a core formed of connective tissue components and presented findings suggesting an origin through vessel loops, endothelialized thrombus, interendothelial bridges, and/or splitting and fusion, and conditioned VT morphology. In conclusion, the findings support the participation of IA and IL, in association with sprouting angiogenesis, in VTs, and therefore in their growth and morphogenesis, which is of pathophysiological interest and lays the groundwork for in-depth molecular studies with therapeutic purposes.

9.
J Strength Cond Res ; 38(4): 762-772, 2024 Apr 01.
Article in English | MEDLINE | ID: mdl-38090743

ABSTRACT

ABSTRACT: Ogrezeanu, DC, López-Bueno, L, Sanchís-Sánchez, E, Carrasco, JJ, Cuenca-Martínez, F, Suso-Martí, L, López-Bueno, R, Cruz-Montecinos, C, Martinez-Valdes, E, Casaña, J, and Calatayud, J. Neuromuscular responses and perceptions of health status and pain-related constructs in end-stage knee osteoarthritis during resistance training with blood flow restriction. J Strength Cond Res 38(4): 762-772, 2024-We aimed to evaluate the neuromuscular responses and their relationship with health status, kinesiophobia, pain catastrophizing, and chronic pain self-efficacy in patients with end-stage knee osteoarthritis during acute resistance training with different levels of blood flow restriction (BFR). Seventeen patients with end-stage knee osteoarthritis participated in 3 experimental sessions separated by 3 days, performing 4 sets of knee extensions with low load and 3 levels of concurrent BFR performed in a random order: control (no BFR), BFR at 40% arterial occlusion pressure (AOP), and BFR at 80% AOP. Normalized root-mean-square (nRMS), nRMS spatial distribution (centroid displacement, modified entropy, and coefficient of variation), and normalized median frequency (nFmed) were calculated from the vastus medialis (VM) and lateralis (VL) using high-density surface electromyography. Subjects were asked to report adverse effects after the sessions. In the VM, nRMS was higher with 80% AOP than with 40% AOP ( p = 0.008) and control ( p < 0.001), whereas there were no differences between conditions in the VL. Normalized root-mean-square also showed an association with pain catastrophizing, chronic pain self-efficacy, and health status (VM: -0.50, 0.49, -0.42; VL: -0.39, 0.27, -0.33). Spatial distribution varied between conditions but mostly in the VL. Overall, nFmed did not vary, with only a slight increase in the VL with 40% AOP, between set 3 and 4. BFR during knee extensions at 80% AOP increases VM activity and VL amplitude distribution more than 40% AOP and control. Importantly, muscle activity increases are modulated by pain catastrophizing, chronic pain self-efficacy, and health status in these patients, and kinesiophobia seems to especially modulate entropy.


Subject(s)
Chronic Pain , Osteoarthritis, Knee , Resistance Training , Humans , Osteoarthritis, Knee/complications , Knee Joint/physiology , Quadriceps Muscle/physiology , Regional Blood Flow/physiology , Health Status , Muscle, Skeletal/physiology
10.
Int Emerg Nurs ; 72: 101383, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38086283

ABSTRACT

AIM: To determine the factors related with the perception of feeling safe during pre-hospital emergency care. METHODS: A multi-centred, cross-sectional study. Data collection from April 2021 to March 2022, in the Centro de Emergencias Sanitarias 061 (Andalusia, Spain). INCLUSION CRITERIA: witnesses of health care by emergency medical services. EXCLUSION CRITERIA: minors, or communication barriers. OUTCOME VARIABLE: Witness Perceived Safety Scale ESPT10. The variables studied were related with sociodemographic data, the request for health care, the patient, the hospital transfer and patient safety incidents. A multivariate linear regression model was constructed for the dependent variable. The study followed STROBE statement. RESULTS: Responses were obtained from 1400 witnesses. The linear regression model showed that the score on the scale increased as the witnesses felt more satisfied (B = 1.302; p < 0.001). On the contrary, the score was lower when the witness reported a patient safety incident (B = -2.856; p < 0.001 and B = -3.166; p < 0.001), or when the assistance took place in a public space (B = -0.722; p = 0.017). CONCLUSIONS: The level of satisfaction, the occurrence of a patient safety incident, and the place of health care are related factors with the perception of the witnesses. The Witness Perceived Safety Scale ESPT10 could be considered a valid and useful patient safety indicator.


Subject(s)
Emergency Medical Services , Patient Safety , Humans , Cross-Sectional Studies , Hospitals , Delivery of Health Care , Perception
11.
Actas esp. psiquiatr ; 52(1): 57-59, Feb. 2024.
Article in English | IBECS | ID: ibc-231257

ABSTRACT

Antibiomanic episodes, or as the DSM-5 refers to them, drug-induced manic episodes, pose a clinical challenge that is still poorly understood. There is insufficient information on the most common clinical presentation, patient profile, or underlying aetiopathogenic mechanisms. We present the clinical case of a 67-year-old woman who, after starting treatment (clarithromycin and amoxicillin) for the eradication of Helicobacter pylori, bacteria presented with a brief manic episode, which resolved after withdrawal of both drugs and with antipsychotic treatment. The possible interaction of both drugs, as GABA antagonists, in the generation of such episodes is discussed, and the clinical importance of such episodes in psychiatric emergency departments and liaison and interconsultation psychiatry, is highlighted. (AU)


Subject(s)
Humans , Female , Aged , Bipolar Disorder/complications , Bipolar Disorder/drug therapy , Clarithromycin/adverse effects , Amoxicillin/adverse effects , Drug Interactions , Helicobacter pylori , Psychiatry
12.
Emergencias ; 35(6): 447-455, 2023 12.
Article in English, Spanish | MEDLINE | ID: mdl-38116969

ABSTRACT

OBJECTIVES: To identify factors related to patients' feeling of safety during prehospital emergencies. MATERIAL AND METHODS: Descriptive, multicenter cross-sectional study in the context of "061" emergency response services of Andalusia, Spain. Data were collected from April 2021 to March 2022. Patients attended and transported by emergency responders were eligible for inclusion. Patients were excluded if they were minors or in an altered state of consciousness, or had cognitive impairment or any barrier to communication. We calculated that a minimum sample size of 644 patients would be required. The outcome variable was the score on a 16-item scale of patient-perceived safety (ESP16, as abbreviated in Spanish). Sociodemographic, emergency service response, patient, and hospital transfer variables were studied in relation to ESP16 score. We also collected patient safety incident reports. Multivariate linear regression was used to analyze associations between the independent variables and the dependent outcome variable. Guidelines for Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) were followed. RESULTS: We received 1756 responses. The mean (SD) ESP16 score was 77.7 (5.6); the median score was 80. The ßô€€ƒ coefficients derived from the linear regression model were as follows for the variables associated with the ESP16 score: 2.799 (P .001) for satisfaction; -6.097 (P .001) for incident reports of errors, falls, harm, or injury; -2.742 (P .001) for reports of any other incident during attendance; 2.538 (P = .001) for use of the transport protocol; 1.157 (P .001) for type of emergency transport used; 0.726 (P = .014) for a cardiology diagnosis; and 1.195 (P = .003) for pain intensity. CONCLUSION: Patients' perception of safety is very high, as reflected by level of satisfaction, incident reports, use of a transport protocol, means of transport used, diagnosis, and pain level.


OBJETIVO: Conocer los factores que se relacionan con la percepción de los pacientes de sentirse seguros en emergencias extrahospitalarias. METODO: Estudio observacional descriptivo, transversal, multicéntrico, en los equipos de emergencias 061 de Andalucía. Se recogieron los datos desde abril 2021 hasta marzo 2022. Criterios de inclusión fueron pacientes asistidos y trasladados por equipos de emergencias, y los criterios de exclusión fueron menores de edad, deterioro cognitivo, alteración de consciencia, o barreras comunicativas. Se calculó un tamaño muestral mínimo de 644 sujetos. La variable resultado fue la puntuación de la Escala de Seguridad Percibida (ESP16). Se estudiaron variables sociodemográficas y relacionadas con la demanda asistencial, el paciente y el traslado. Además, se recogieron notificaciones de incidentes relacionados con la seguridad del paciente (IRSP). Se construyó un modelo de regresión lineal multivariable para la variable dependiente. Se siguieron las recomendaciones STROBE. RESULTADOS: Se obtuvieron 1.756 respuestas. La puntuación media en la ESP16 fue 77,7 (DE 5,6), con mediana de 80. El modelo de regresión lineal mostró que el nivel de satisfacción (B = 2,799; p 0,001), la notificación de error, caída, daño o lesión (B = ­6,097; p 0,001), la notificación de cualquier otro IRSP (B = ­2,742; p 0,001), la transferencia protocolizada (B = 2,538; p = 0,001), el tipo de recurso asistencial (B = 1,157; p 0,001), un diagnóstico final cardiológico (B = 0,726; p = 0,014) y un nivel de dolor intenso (B = 1,195; p = 0,003) influían en la escala ESP16. CONCLUSIONES: La percepción de seguridad del paciente es muy alta, y está condicionada por el nivel de satisfacción, la notificación de IRSP, la transferencia protocolizada, el recurso asistencial, el diagnóstico final y el nivel de dolor.


Subject(s)
Emergencies , Emergency Medical Services , Patient Safety , Humans , Cross-Sectional Studies , Hospitals , Perception
13.
Emergencias (Sant Vicenç dels Horts) ; 35(6): 447-455, dic. 2023. ilus, tab
Article in Spanish | IBECS | ID: ibc-227808

ABSTRACT

Objetivos: Conocer los factores que se relacionan con la percepción de los pacientes de sentirse seguros en emergencias extrahospitalarias. Método: Estudio observacional descriptivo, transversal, multicéntrico, en los equipos de emergencias 061 de Andalucía. Se recogieron los datos desde abril 2021 hasta marzo 2022. Criterios de inclusión fueron pacientes asistidos y trasladados por equipos de emergencias, y los criterios de exclusión fueron menores de edad, deterioro cognitivo, alteración de consciencia, o barreras comunicativas. Se calculó un tamaño muestral mínimo de 644 sujetos. La variable resultado fue la puntuación de la Escala de Seguridad Percibida (ESP16). Se estudiaron variables sociodemográficas y relacionadas con la demanda asistencial, el paciente y el traslado. Además, se recogieron notificaciones de incidentes relacionados con la seguridad del paciente (IRSP). Se construyó un modelo de regresión lineal multivariable para la variable dependiente. Se siguieron las recomendaciones STROBE. Resultados: Se obtuvieron 1.756 respuestas. La puntuación media en la ESP16 fue 77,7 (DE 5,6), con mediana de 80. El modelo de regresión lineal mostró que el nivel de satisfacción (B = 2,799; p < 0,001), la notificación de error, caída, daño o lesión (B = –6,097; p < 0,001), la notificación de cualquier otro IRSP (B = –2,742; p < 0,001), la transferencia protocolizada (B = 2,538; p = 0,001), el tipo de recurso asistencial (B = 1,157; p < 0,001), un diagnóstico final cardiológico (B = 0,726; p = 0,014) y un nivel de dolor intenso (B = 1,195; p = 0,003) influían en la escala ESP16. Conclusiones: La percepción de seguridad del paciente es muy alta, y está condicionada por el nivel de satisfacción, la notificación de IRSP, la transferencia protocolizada, el recurso asistencial, el diagnóstico final y el nivel de dolor. (AU)


Aim: To identify factors related to patients’ feeling of safety during prehospital emergencies. Methods: Descriptive, multicenter cross-sectional study in the context of “061” emergency response services of Andalusia, Spain. Data were collected from April 2021 to March 2022. Patients attended and transported by emergency responders were eligible for inclusion. Patients were excluded if they were minors or in an altered state of consciousness, or had cognitive impairment or any barrier to communication. We calculated that a minimum sample size of 644 patients would be required. The outcome variable was the score on a 16-item scale of patient-perceived safety (ESP16, as abbreviated in Spanish). Sociodemographic, emergency service response, patient, and hospital transfer variables were studied in relation to ESP16 score. We also collected patient safety incident reports.Multivariate linear regression was used to analyze associations between the independent variables and the dependent outcome variable. Guidelines for Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) were followed. Results: We received 1756 responses. The mean (SD) ESP16 score was 77.7 (5.6); the median score was 80. The b coefficients derived from the linear regression model were as follows for the variables associated with the ESP16 score: 2.799 (P < .001) for satisfaction; –6.097 (P < .001) for incident reports of errors, falls, harm, or injury; –2.742 (P < .001) for reports of any other incident during attendance; 2.538 (P = .001) for use of the transport protocol; 1.157 (P < .001) for type of emergency transport used; 0.726 (P = .014) for a cardiology diagnosis; and 1.195 (P = .003) for pain intensity. Conclusions: Patients’ perception of safety is very high, as reflected by level of satisfaction, incident reports, use of a transport protocol, means of transport used, diagnosis, and pain level. (AU)


Subject(s)
Humans , Male , Female , Young Adult , Adult , Middle Aged , Aged , Aged, 80 and over , Emergencies , Perception , Patient Safety , Cross-Sectional Studies , Epidemiology, Descriptive , Spain , Emergency Medical Services
14.
Healthcare (Basel) ; 11(19)2023 Sep 27.
Article in English | MEDLINE | ID: mdl-37830668

ABSTRACT

(1) Background: This study aimed to examine the relationship between Spanish physical therapists' perceptions of the ethical climate, their moral sensitivity (awareness of ethical issues), and job satisfaction. (2) Methods: the study analyzed descriptive correlational data on 104 physical therapists from three Spanish metropolitan hospitals. Respondents completed a demographic data form, an ethical climate questionnaire, a job satisfaction survey, and a moral sensitivity scale. This study complies with the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines. (3) Results: With a mean score of 4.2, physical therapists are typically content with their jobs. The mean scores for the moral sensitivity and ethical climate questionnaires are high, at 40.1 (SD 6.3) and 96.8 (SD 17.1), respectively. There is a significant positive correlation between job satisfaction and ethical climate (r between 0.59 and 0.79) but only a weak correlation between job satisfaction and moral sensibility (r between 0 and 0.32 for the three aspects measured). (4) Conclusions: Generally speaking, physical therapists reported that they had high job satisfaction, a positive workplace environment, and excellent management support. Despite a weak relationship with moral sensibility, there is a strong association between ethical behavior, hospital organization, and higher levels of job satisfaction. It is important to encourage the development of moral sensibilities to boost psychological well-being and therapeutic decision-making.

15.
Biomedicines ; 11(10)2023 Sep 22.
Article in English | MEDLINE | ID: mdl-37892976

ABSTRACT

Stroke-related sarcopenia has recently been defined as the muscle atrophy consequent to stroke and assessing it following the guidelines with simple clinical tools is crucial in chronic stroke survivors. The aim of this study was to determine the characteristics of patient-friendly instruments sarcopenia in a chronic stroke sample (SG) compared to non-stroke counterparts (CG). Each participant underwent a single assessment which consisted of: SARC-F questionnaire, assessment of muscle strength (hand grip and five-times sit-to-stand test, 5STS), the calf circumference (CC) of both legs, the short physical performance battery (SPPB), and the 10 m walk test. A total of 68 participants were included (SG, n = 34 and CG, n = 34). All variables showed statistical differences (p < 0.05) between the SG and the CG, except handgrip although it showed lower values for SG. The values of the 5STS (16.26 s) and the SPPB (7 points) were below to the cutoff values for the SG. The five-times sit-to-stand test, SPPB, and gait speed can lead clinicians to detect stroke-related sarcopenia. Maximum handgrip shows a trend of low values for men and women in the SG, however, CC did not detect sarcopenia in our sample.

17.
Clin. transl. oncol. (Print) ; 25(9): 2707-2717, sept. 2023. ilus, tab
Article in English | IBECS | ID: ibc-224135

ABSTRACT

Gastrointestinal stromal tumor (GIST) is the most common malignant neoplasm of mesenchymal origin, and a paradigmatic model for a successful rational development of targeted therapies in cancer. The introduction of tyrosine kinase inhibitors with activity against KIT/PDGFRA in both localized and advanced stages has remarkably improved the survival in a disease formerly deemed resistant to all systemic therapies. These guidelines are elaborated by the conjoint effort of the Spanish Society of Medical Oncology (SEOM) and the Spanish Sarcoma Research Group (GEIS) and provide a multidisciplinary and updated consensus for the diagnosis and treatment of GIST patients. We strongly encourage that the managing of these patients should be performed within multidisciplinary teams in reference centers (AU)


Subject(s)
Humans , Gastrointestinal Stromal Tumors/diagnosis , Gastrointestinal Stromal Tumors/therapy , Societies, Medical , Spain
19.
BMC Psychiatry ; 23(1): 579, 2023 08 10.
Article in English | MEDLINE | ID: mdl-37563600

ABSTRACT

BACKGROUND: The media portrayal of mental health is relevant in shaping the population's attitudes towards mental disorders. However, there is little information about the representation of young mental health issues in the Spanish-language press, especially in the context of the COVID-19 pandemic. The general objective of this study was to analyse the tone and content of Spanish newspaper articles about mental disorders in youth during the COVID-19 pandemic. METHODS: We collected media articles from the 10 most read news sources over a 6 month period (January-June 2021). These articles were coded for content using a standardised codebook, followed by an inductive thematic analysis. A total of 205 news items were evaluated. RESULTS: Results showed that the majority of the news items had an overall positive tone (68.3%), only 5.4% were stigmatising and only 7.3% were related to violence. However, few articles offered help seeking information (6%), adolescents were rarely quoted (14%) and children were never quoted. Substantial differences are described in terms of age, gender and disorder. The thematic analysis led to three emergent themes: (i) violence and victimisation; (ii) the COVID-19 pandemic; and (iii) technology and social media. CONCLUSIONS: The percentage of news in the Spanish media that refer to young people's mental health in a stigmatising way or in a way associated with violence is very low. Furthermore, the COVID-19 pandemic may have promoted more positive discussion about youth mental health. However, major challenges remain to be addressed, as patients are seldom quoted, very few articles offer help-seeking information, and a narrative of victimisation without appropriate discussion of resilience regularly occurs.


Subject(s)
COVID-19 , Mental Disorders , Social Media , Child , Humans , Adolescent , Mental Health , Mass Media , Pandemics , Mental Disorders/psychology
20.
Clin Genet ; 104(4): 427-433, 2023 10.
Article in English | MEDLINE | ID: mdl-37329267

ABSTRACT

Despite compelling evidence that some patients with a psychiatric diagnosis could benefit from genetic assessment, genetic testing for psychiatric patients is underutilized. Few studies have reported psychiatric genetics training for mental health specialists, and such research is especially lacking in Spain. We aimed to gather the opinions of Spanish mental health residents, including resident intern nurses (RINs), doctors (RIDs) and psychologists (RIPs). A short survey was prepared by an expert team and distributed to all mental health residency centers in Spain during the first semester of 2021. Of the 2028 residents, 18% responded. Participants were mainly females (71%), in their first year of residency (37%) and within the 27-31-year age range. While participants received little theoretical (13.4%) and practical (4.6%) training on average, RIDs had the most affirmative responses. Notably, RINs and RIDs were interested in genetics during residency (>40%) and strongly believed (85.0%) that genetics training using both theoretical and practical methodologies should be incorporated into residency training. However, RIPs were less interested (20%), and only 60% believed that genetics training should be incorporated. Spanish mental health residents, although interested in genetics in psychiatry, receive little training on this topic. They strongly believe that genetics training using theoretical and practical methodologies should be incorporated.


Subject(s)
Internship and Residency , Mental Disorders , Female , Humans , Male , Cross-Sectional Studies , Mental Health , Mental Disorders/genetics , Surveys and Questionnaires
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