The protective effect of wild mustard (Sinapis arvensis L) pollen seeds against the toxicity of a solvent (EGME) in Wistar rats

Environmental pollution is the unfavorable alteration of our environment, wholly or mainly as a by-product of human actions, by the direct or indirect effects of changes in energy patterns, radiation levels, the chemical and physical constitution, and the abundance of the organisms. Thus, the environment's pollution is one of the most severe problems humanity and other forms of life face today on our planet, and this population makes severe disruption. The xenobiotic substances responsible for this pollution are numerous and diverse due to multiple human activities that can be the source. However, attention mainly focuses on fertilizers, pesticides, heavy metals, and certain petrochemicals of significant consumption, such as solvents. The purpose of this study is to highlight the reprotoxic and hepatotoxic effects of Ethylene Glycol Monoethyl Ether (EGME) on male Wistar rats. Male Wistar rats were exposed to Ethylene Glycol Monomethyl Etheralone (EGME) (500 mg/kg), combined with the aqueous extract of the pollen grains of Sinapis arvensis (P-EGME) (300mg/kg), in addition to the control (T) and positive control (P) groups for a period of 4 weeks by gavage, to estimate the protective role of this plant against the intoxication of EGME. The results show that EGME can induce reprotoxic effects revealed by a reduction in testes and epididymis mass accompanied by decreased male fertility indicators (sperm concentration). The results also show that treatment with EGME caused a reduction in the red blood cell number, hemoglobin and hematocrit rate, white blood cells in the treated groups compared to the control groups. The present study revealed that treatment with Ethylene Glycol Monoethyl Ether (EGME) under the same experimental conditions could affect several biological markers, especially male fertility. Besides, the protective activity of the wild mustard (Sinapis arvensis) pollen in the face of cellular [...] (AU)

The protective effect of wild mustard (Sinapis arvensis L) pollen seeds against the toxicity of a solvent (EGME) in Wistar rats

Environmental pollution is the unfavorable alteration of our environment, wholly or mainly as a by-product of human actions, by the direct or indirect effects of changes in energy patterns, radiation levels, the chemical and physical constitution, and the abundance of the organisms. Thus, the environment's pollution is one of the most severe problems humanity and other forms of life face today on our planet, and this population makes severe disruption. The xenobiotic substances responsible for this pollution are numerous and diverse due to multiple human activities that can be the source. However, attention mainly focuses on fertilizers, pesticides, heavy metals, and certain petrochemicals of significant consumption, such as solvents. The purpose of this study is to highlight the reprotoxic and hepatotoxic effects of Ethylene Glycol Monoethyl Ether (EGME) on male Wistar rats. Male Wistar rats were exposed to Ethylene Glycol Monomethyl Etheralone (EGME) (500 mg/kg), combined with the aqueous extract of the pollen grains of Sinapis arvensis (P-EGME) (300mg/kg), in addition to the control (T) and positive control (P) groups for a period of 4 weeks by gavage, to estimate the protective role of this plant against the intoxication of EGME. The results show that EGME can induce reprotoxic effects revealed by a reduction in testes and epididymis mass accompanied by decreased male fertility indicators (sperm concentration). The results also show that treatment with EGME caused a reduction in the red blood cell number, hemoglobin and hematocrit rate, white blood cells in the treated groups compared to the control groups. The present study revealed that treatment with Ethylene Glycol Monoethyl Ether (EGME) under the same experimental conditions could affect several biological markers, especially male fertility. Besides, the protective activity of the wild mustard (Sinapis arvensis) pollen in the face of cellular [...]

Neurobehavioral and hepatic complications induced by acute inhalation exposure to abamectin in female rats of the Wistar strain treated with ginger (Zingiber officinale)

The study we conducted aimed to evaluate the acute toxicity of abamectin (ABM) (pesticide) on liver function and neurobehavioral by using the open field test. As a therapy, we have opted for a treatment based on natural antioxidants ginger extract (Zingiber officinale) mixed with olive oil to see the restorative effects during the experiment. The study was conducted on female Wistar rats. The latter was given an inhalation exposure of abamectin (ABM) at a dose CL50 > 5.04mg/L/1hr each morning for one week. The effects of this exposure showed a drop in body weight gain (g), a significant decrease in the relative and absolute weights liver (gm/100 gm body weight) accompanied by hepatic impairment indicating a significant disturbance of transaminases (AST/ALT), alkaline phosphatase (ALP) activity and significant behavioral changes. Administration of ginger (Zingiber officinale) extract at a dose of 3 ml mixed with olive oil at a dose of 1 ml/kg for 7 days orally (gavages) after inhalation indicates that ginger has a more remarkable and rapid effect on physical and mental health, it acts as a major means of defense and hepato-protective against toxicity.(AU)

Bio-ecological study of the water mites (Acari: Hydracarina) of the pond of El-Goureate in the National Park of El-Kala (North-East of Algeria)

This study aimed to present faunistic and ecological data on aquatic mites living in small permanent basins andselected lakes in the El-Kala National Park (Northeast of Algeria). Thus, this study shows the research of Hydracarina in the park comprehensively over the two years. We have identified the living Hydracarina species in the semi-temporary studysite at Goureate pond. The existence of an unknown and interesting Hydracarina fauna has been revealed. The collection of specimens revealed the presence of 9 species divided into 5 families. The identification required the study of ecological indices and the measurement of physicochemical parameters (temperature, humidity). The results of the univariate analysisof variance test fixed model, applied to each of the 9 physicochemical variables and a variable related to the number ofHydracarina, for two years. The results showed a very highly significant difference for water temperature and atmospheric temperature and a just significant difference for the number of Hydracarina, while no significant difference for pH, humidity, conductivity, NO-2, PO-4, NH+4 is registered, and the study of the abundance of the identified species in the four stations during the four seasons.(AU)

Neurobehavioral and hepatic complications induced by acute inhalation exposure to abamectin in female rats of the Wistar strain treated with ginger (Zingiber officinale)

The study we conducted aimed to evaluate the acute toxicity of abamectin (ABM) (pesticide) on liver function and neurobehavioral by using the open field test. As a therapy, we have opted for a treatment based on natural antioxidants ginger extract (Zingiber officinale) mixed with olive oil to see the restorative effects during the experiment. The study was conducted on female Wistar rats. The latter was given an inhalation exposure of abamectin (ABM) at a dose CL50 > 5.04mg/L/1hr each morning for one week. The effects of this exposure showed a drop in body weight gain (g), a significant decrease in the relative and absolute weights liver (gm/100 gm body weight) accompanied by hepatic impairment indicating a significant disturbance of transaminases (AST/ALT), alkaline phosphatase (ALP) activity and significant behavioral changes. Administration of ginger (Zingiber officinale) extract at a dose of 3 ml mixed with olive oil at a dose of 1 ml/kg for 7 days orally (gavages) after inhalation indicates that ginger has a more remarkable and rapid effect on physical and mental health, it acts as a major means of defense and hepato-protective against toxicity.(AU)

Bio-ecological study of the water mites (Acari: Hydracarina) of the pond of El-Goureate in the National Park of El-Kala (North-East of Algeria)

This study aimed to present faunistic and ecological data on aquatic mites living in small permanent basins andselected lakes in the El-Kala National Park (Northeast of Algeria). Thus, this study shows the research of Hydracarina in the park comprehensively over the two years. We have identified the living Hydracarina species in the semi-temporary studysite at Goureate pond. The existence of an unknown and interesting Hydracarina fauna has been revealed. The collection of specimens revealed the presence of 9 species divided into 5 families. The identification required the study of ecological indices and the measurement of physicochemical parameters (temperature, humidity). The results of the univariate analysisof variance test fixed model, applied to each of the 9 physicochemical variables and a variable related to the number ofHydracarina, for two years. The results showed a very highly significant difference for water temperature and atmospheric temperature and a just significant difference for the number of Hydracarina, while no significant difference for pH, humidity, conductivity, NO-2, PO-4, NH+4 is registered, and the study of the abundance of the identified species in the four stations during the four seasons.(AU)

Bio-ecological study of the water mites (Acari: Hydracarina) of the pond of El-Goureate in the National Park of El-Kala (North-East of Algeria)

This study aimed to present faunistic and ecological data on aquatic mites living in small permanent basins andselected lakes in the El-Kala National Park (Northeast of Algeria). Thus, this study shows the research of Hydracarina in the park comprehensively over the two years. We have identified the living Hydracarina species in the semi-temporary studysite at Goureate pond. The existence of an unknown and interesting Hydracarina fauna has been revealed. The collection of specimens revealed the presence of 9 species divided into 5 families. The identification required the study of ecological indices and the measurement of physicochemical parameters (temperature, humidity). The results of the univariate analysisof variance test fixed model, applied to each of the 9 physicochemical variables and a variable related to the number ofHydracarina, for two years. The results showed a very highly significant difference for water temperature and atmospheric temperature and a just significant difference for the number of Hydracarina, while no significant difference for pH, humidity, conductivity, NO-2, PO-4, NH+4 is registered, and the study of the abundance of the identified species in the four stations during the four seasons.

Neurobehavioral and hepatic complications induced by acute inhalation exposure to abamectin in female rats of the Wistar strain treated with ginger (Zingiber officinale)

The study we conducted aimed to evaluate the acute toxicity of abamectin (ABM) (pesticide) on liver function and neurobehavioral by using the open field test. As a therapy, we have opted for a treatment based on natural antioxidants ginger extract (Zingiber officinale) mixed with olive oil to see the restorative effects during the experiment. The study was conducted on female Wistar rats. The latter was given an inhalation exposure of abamectin (ABM) at a dose CL50 > 5.04mg/L/1hr each morning for one week. The effects of this exposure showed a drop in body weight gain (g), a significant decrease in the relative and absolute weights liver (gm/100 gm body weight) accompanied by hepatic impairment indicating a significant disturbance of transaminases (AST/ALT), alkaline phosphatase (ALP) activity and significant behavioral changes. Administration of ginger (Zingiber officinale) extract at a dose of 3 ml mixed with olive oil at a dose of 1 ml/kg for 7 days orally (gavages) after inhalation indicates that ginger has a more remarkable and rapid effect on physical and mental health, it acts as a major means of defense and hepato-protective against toxicity.

The effect of oral gavage (force-feeding) administration of fenugreek seeds (Trigonella foenum-graecum L. ) on biochemical and neurobehavioural parameters in male Wistar rats

This study aims to evaluate the effect of fenugreek on biochemical parameters, body weight, and the behavior of male Wistar rats. The purpose of administering the aqueous extract of fenugreek seeds (Trigonella foenum-graecum L) for 30 successive days by oral gavage (force-feeding) at a dose of 250g / l of water is intended to assess, on the one hand, the neurobehavioural effects and on the other hand its effect on some biochemical parameters (glycemia and lipid balance) as well as weight. The behavioral tests performed are the Light/Dark Box tests (LDB) and the Elevated Plus Maze test (EPM). This work indicated that the consumption of the aqueous extract of the seeds of fenugreek is beneficial to stimulate appetite and gain weight, thus decreasing the level of total cholesterol, triglycerides, LDL-C, and a significant increase in HDL-C, also a reduction in blood sugar and a decrease in anxiety.(AU)

The effect of oral gavage (force-feeding) administration of fenugreek seeds (Trigonella foenum-graecum L. ) on biochemical and neurobehavioural parameters in male Wistar rats

This study aims to evaluate the effect of fenugreek on biochemical parameters, body weight, and the behavior of male Wistar rats. The purpose of administering the aqueous extract of fenugreek seeds (Trigonella foenum-graecum L) for 30 successive days by oral gavage (force-feeding) at a dose of 250g / l of water is intended to assess, on the one hand, the neurobehavioural effects and on the other hand its effect on some biochemical parameters (glycemia and lipid balance) as well as weight. The behavioral tests performed are the Light/Dark Box tests (LDB) and the Elevated Plus Maze test (EPM). This work indicated that the consumption of the aqueous extract of the seeds of fenugreek is beneficial to stimulate appetite and gain weight, thus decreasing the level of total cholesterol, triglycerides, LDL-C, and a significant increase in HDL-C, also a reduction in blood sugar and a decrease in anxiety.

Hepatoprotective effect of Zinc and Magnesium against subchronicCadmium toxicity on biochemical, histopathological andneurobehavioral parameters in Wistar rats

The aim of this study was carried out to investigate the possible hepato protective effect of Zinc and Magnesium against subchronic cadmium toxicity on biochemical, histopathological and neurobehavioral parameters in Wistar rats during 90 days. Fourty Wistar rats, were randomly divided in four experimental group: 1, control only water; 2, water and oral administration (Cd); 3, (Cd+Mg) in water oral administration; 4, (Cd+Zn) in water oral administration. Zinc and Magnesium was used to reduce hepatoxicity and neurobehavioral disorders induced by Cadmium in Wistar rats. The Cd-Zn and Cd-Mg groups received 10 mg/kg of ZnCl2, 10 mg/kg of MgCl2 added to drinking water. The Cd group received 15mg / kg of CdCl2. Blood glucose level and body weight were measured every day. According to the results, which have been obtained. There was a reduction in body weight gain due to Cd group and an increase liver weight. The results indicated also changes in biochemical parameters, which are characterized by an increase in serum glucose, serum urea, serum creatinine, of animals contaminated with cadmium compared to the control animals. However, the supplementation of (Zn) and Mg combination improved some but not all the previous parameters. Moreover, the findings showed variation in hematological parameters of Cd treated animals. In other word, there was a rise in number of white cells, and reduction of red cells counts, hemoglobin concentration and hematocrit percentage, but all these parameters returned approximately to their normal values after combined Zn and Mg addition. The neurobehavioral test shows an increase in the number of cells crossed, the number of straightening in the test. Open field in the group exposed to Cd resulting in locomotors hyperactivity compared to the control and it is minimal in other groups treated with Zn and Mg...(AU)

Hepatoprotective effect of Zinc and Magnesium against subchronicCadmium toxicity on biochemical, histopathological andneurobehavioral parameters in Wistar rats

The aim of this study was carried out to investigate the possible hepato protective effect of Zinc and Magnesium against subchronic cadmium toxicity on biochemical, histopathological and neurobehavioral parameters in Wistar rats during 90 days. Fourty Wistar rats, were randomly divided in four experimental group: 1, control only water; 2, water and oral administration (Cd); 3, (Cd+Mg) in water oral administration; 4, (Cd+Zn) in water oral administration. Zinc and Magnesium was used to reduce hepatoxicity and neurobehavioral disorders induced by Cadmium in Wistar rats. The Cd-Zn and Cd-Mg groups received 10 mg/kg of ZnCl2, 10 mg/kg of MgCl2 added to drinking water. The Cd group received 15mg / kg of CdCl2. Blood glucose level and body weight were measured every day. According to the results, which have been obtained. There was a reduction in body weight gain due to Cd group and an increase liver weight. The results indicated also changes in biochemical parameters, which are characterized by an increase in serum glucose, serum urea, serum creatinine, of animals contaminated with cadmium compared to the control animals. However, the supplementation of (Zn) and Mg combination improved some but not all the previous parameters. Moreover, the findings showed variation in hematological parameters of Cd treated animals. In other word, there was a rise in number of white cells, and reduction of red cells counts, hemoglobin concentration and hematocrit percentage, but all these parameters returned approximately to their normal values after combined Zn and Mg addition. The neurobehavioral test shows an increase in the number of cells crossed, the number of straightening in the test. Open field in the group exposed to Cd resulting in locomotors hyperactivity compared to the control and it is minimal in other groups treated with Zn and Mg...