ABSTRACT
No disponible
Subject(s)
Humans , Child , Adolescent , Food Hypersensitivity/diet therapy , Food Hypersensitivity/drug therapy , Food Hypersensitivity/prevention & control , Schools , Anaphylaxis , Spain , BullyingABSTRACT
Background and objectives Based on previous studies revealing acid-suppression medication as a risk factor for food allergy tolerance induction, we aimed to establish the importance of those findings in patients undergoing oral immunotherapy (OIT). Materials and methods, results We describe a case series of four patients who underwent milk OIT with a concomitant use of proton pump inhibitor (PPI) medication and who developed anaphylaxis after a known, previously tolerated dose of milk. Conclusions PPIs may act as a cofactor in patients undergoing OIT, triggering adverse reactions, irrespective of the PPI used or the dosage. It would be necessary to separate the administration of drug from food intake. Since OIT is a new form of treatment, long-term adverse events arising from PPI treatment and other possible triggers are still uncertain. Consequently, monitoring of patient must be prolonged over time. Additional investigations on the influence of different drugs in OIT maintenance phase are required (AU)
Subject(s)
Humans , Male , Female , Child , Anaphylaxis/etiology , Desensitization, Immunologic/methods , Eosinophilic Esophagitis/therapy , Food Hypersensitivity/therapy , Gastritis/therapy , Proton Pump Inhibitors/adverse effectsSubject(s)
Nut Hypersensitivity/immunology , Nut Hypersensitivity/prevention & control , Nuts/immunology , Allergens/immunology , Dermatitis, Atopic/epidemiology , Dermatitis, Atopic/immunology , Disease Management , Humans , Immunization , Nut Hypersensitivity/epidemiology , Nuts/adverse effects , Nuts/classification , Peanut Hypersensitivity/epidemiology , Peanut Hypersensitivity/immunology , Peanut Hypersensitivity/prevention & controlSubject(s)
Dietary Proteins/adverse effects , Enterocolitis/epidemiology , Food Hypersensitivity/epidemiology , Child, Preschool , Dietary Proteins/administration & dosage , Enterocolitis/chemically induced , Enterocolitis/immunology , Female , Food Hypersensitivity/immunology , Humans , Infant , Infant, Newborn , Longitudinal Studies , Male , Prevalence , Prospective StudiesABSTRACT
Vaccinations are one of the main public health tools for the control of vaccine-preventable diseases. If a child is identified as having had an allergic reaction to a vaccine, subsequent immunisations will probably be suspended - with the risks such a decision implies. The incidence of severe allergic reactions is very low, ranging between 0.5 and 1 cases/100,000 doses. Rather than the vaccine antigens as such, the causes of allergic reactions to vaccines are often residual protein components of the manufacturing process such as gelatine or egg, and less commonly yeasts or latex. Most vaccine reactions are mild and circumscribed to the injection site; although in some cases severe anaphylactic reactions can be observed. If an immediate-type allergic reaction is suspected at vaccination, or if a child with allergy to some of the vaccine components is scheduled for vaccination, a correct diagnosis of the possible allergic process must be made. The usual vaccine components must be known in order to determine whether vaccination can be safely performed
No disponible
Subject(s)
Humans , Male , Female , Child , Hypersensitivity/complications , Hypersensitivity/immunology , Vaccines/adverse effects , Vaccines/immunology , Diagnosis, Differential , Immunization/trends , Immunization , Immunoglobulin G/immunology , Skin Tests/instrumentation , Skin Tests/methods , Vaccines/classification , Hypersensitivity/epidemiology , Hypersensitivity/prevention & control , Vaccination/methods , Vaccination , Surveys and Questionnaires , Medical History Taking/methodsABSTRACT
Vaccinations are one of the main public health tools for the control of vaccine-preventable diseases. If a child is identified as having had an allergic reaction to a vaccine, subsequent immunisations will probably be suspended - with the risks such a decision implies. The incidence of severe allergic reactions is very low, ranging between 0.5 and 1 cases/100,000 doses. Rather than the vaccine antigens as such, the causes of allergic reactions to vaccines are often residual protein components of the manufacturing process such as gelatine or egg, and less commonly yeasts or latex. Most vaccine reactions are mild and circumscribed to the injection site; although in some cases severe anaphylactic reactions can be observed. If an immediate-type allergic reaction is suspected at vaccination, or if a child with allergy to some of the vaccine components is scheduled for vaccination, a correct diagnosis of the possible allergic process must be made. The usual vaccine components must be known in order to determine whether vaccination can be safely performed.