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1.
Cir Pediatr ; 36(2): 90-92, 2023 Apr 01.
Article in English, Spanish | MEDLINE | ID: mdl-37093119

ABSTRACT

INTRODUCTION: The extensor digitorum brevis manus (EDBM) is an accessory muscle of the dorsum of the hand that may appear as a painful mass. It is treated surgically, usually by excision of the muscle. CASE REPORT: 14-year-old male with bilateral painful masses on the dorsal aspect of his hands. Ultrasound confirmed the diagnosis of EDBM. Due to the associated symptoms, decision was made to conduct surgical treatment with resection of both muscle masses. DISCUSSION: EDBM is an infrequent cause of wrist pain, especially in children and adolescents. Surgical treatment has proven to have a significant impact on the improvement of the symptoms suffered by these patients.


INTRODUCCION: El extensor digitorum brevis manus (EDBM) es un músculo accesorio del dorso de la mano que puede presentarse como una masa dolorosa. Su tratamiento es quirúrgico, generalmente consiste en la extirpación del mismo. CASO CLINICO: Varón de 14 años que presenta tumoraciones dolorosas bilaterales en la cara dorsal de las manos. La ecografía confirma el diagnóstico de EDBM. Debido a la sintomatología asociada, se decide tratamiento quirúrgico, con resección de ambas masas musculares. COMENTARIOS: El EDBM constituye una causa poco frecuente de dolor a nivel de la muñeca, especialmente en población infanto-juvenil. El tratamiento quirúrgico ha demostrado un impacto significativo en la mejoría de la sintomatología que presentan estos pacientes.


Subject(s)
Hand , Muscle, Skeletal , Male , Adolescent , Child , Humans , Muscle, Skeletal/surgery , Hand/surgery , Pain/etiology
2.
Cir. pediátr ; 36(2): 90-92, Abr. 2023. ilus, tab
Article in Spanish | IBECS | ID: ibc-218880

ABSTRACT

Introducción: El extensor digitorum brevis manus (EDBM) es unmúsculo accesorio del dorso de la mano que puede presentarse comouna masa dolorosa. Su tratamiento es quirúrgico, generalmente consisteen la extirpación del mismo. Caso clínico: Varón de 14 años que presenta tumoraciones dolorosas bilaterales en la cara dorsal de las manos. La ecografía confirma eldiagnóstico de EDBM. Debido a la sintomatología asociada, se decidetratamiento quirúrgico, con resección de ambas masas musculares. Comentarios: El EDBM constituye una causa poco frecuente dedolor a nivel de la muñeca, especialmente en población infanto-juvenil.El tratamiento quirúrgico ha demostrado un impacto significativo en lamejoría de la sintomatología que presentan estos pacientes.(AU)


Introduction: The extensor digitorum brevis manus (EDBM) isan accessory muscle of the dorsum of the hand that may appear as apainful mass. It is treated surgically, usually by excision of the muscle. Clinical case: 14-year-old male with bilateral painful masses onthe dorsal aspect of his hands. Ultrasound confirmed the diagnosis ofEDBM. Due to the associated symptoms, decision was made to conductsurgical treatment with resection of both muscle masses. Discussion: EDBM is an infrequent cause of wrist pain, especiallyin children and adolescents. Surgical treatment has proven to have asignificant impact on the improvement of the symptoms suffered bythese patients.(AU)


Subject(s)
Humans , Male , Adolescent , Wrist Injuries , Muscles , Wrist/anatomy & histology , Wrist/abnormalities , Wrist/surgery , Musculoskeletal Abnormalities , Pediatrics
3.
Cir Pediatr ; 35(4): 207-211, 2022 Oct 01.
Article in English, Spanish | MEDLINE | ID: mdl-36217792

ABSTRACT

OBJECTIVES: The treatment of keloid scars is based on multiple lines of therapy, with varying levels of efficacy(1), and there is currently no single treatment that guarantees cure and prevents recurrence. In the pediatric population, the treatments used are not standardized, and there is insufficient evidence to support efficacy and complications. The objective of this study was to analyze the patients who required brachytherapy as an adjuvant to surgical resection in recurrent keloid scars. MATERIALS AND METHODS: A retrospective analysis of patients diagnosed with keloids and undergoing adjuvant brachytherapy in our institution was carried out, while assessing efficacy and implementation in our treatment protocol for keloid scarring. RESULTS: After various therapeutic lines, 4 patients aged 9-17 years old with recurrent keloid scars around the ear and eligible for adjuvant brachytherapy - administered after surgical resection, in two sessions - were studied and followed up for up to 18-21 months. CONCLUSIONS: Despite our limited experience in the use of adjuvant brachytherapy, the results obtained to date support its efficacy, as reported in the literature. We therefore consider its inclusion in the treatment of keloid scars that have recurred after other treatments to be appropriate.


OBJETIVOS: El tratamiento de las cicatrices queloideas se basa en múltiples líneas terapéuticas, con diferentes niveles de eficacia(1), sin existir actualmente un tratamiento que garantice su curación y prevenga su recurrencia. En la población pediátrica los tratamientos empleados no están estandarizados y no hay evidencia suficiente que avale su eficacia y sus complicaciones. Este trabajo tiene como objetivo analizar los pacientes que han precisado braquiterapia coadyuvante a la resección quirúrgica en cicatrices queloideas recidivantes. MATERIAL Y METODOS: Análisis retrospectivo de los pacientes diagnosticados en nuestro centro de cicatriz queloidea, en los que se realizó braquiterapia coadyuvante, valorando su eficacia y su implementación en nuestro protocolo de tratamiento de la cicatriz queloidea. RESULTADOS: Se estudiaron 4 pacientes entre 9-17 años con cicatrices queloideas a nivel auricular, recidivantes a varias líneas terapéuticas, que fueron candidatos para el uso de braquiterapia coadyuvante, administrada posterior a la resección quirúrgica, en dos sesiones, se realizó seguimiento hasta 18-21 meses. CONCLUSIONES: A pesar de nuestra limitada experiencia en el uso de la braquiterapia coadyuvante, los resultados obtenidos hasta la fecha avalan su eficacia, de acuerdo con lo publicado en la literatura. Consideramos adecuada su inclusión en el tratamiento de cicatrices queloideas recidivantes a otros tratamientos.


Subject(s)
Brachytherapy , Keloid , Adolescent , Brachytherapy/methods , Child , Humans , Keloid/complications , Keloid/radiotherapy , Keloid/surgery , Recurrence , Retrospective Studies , Treatment Outcome
4.
Cir. pediátr ; 35(4): 207-211, Oct. 2022. ilus, tab
Article in Spanish | IBECS | ID: ibc-210864

ABSTRACT

Objetivos: El tratamiento de las cicatrices queloideas se basa enmúltiples líneas terapéuticas, con diferentes niveles de eficacia (1) , sinexistir actualmente un tratamiento que garantice su curación y prevengasu recurrencia. En la población pediátrica los tratamientos empleados noestán estandarizados y no hay evidencia suficiente que avale su eficaciay sus complicaciones. Este trabajo tiene como objetivo analizar lospacientes que han precisado braquiterapia coadyuvante a la resecciónquirúrgica en cicatrices queloideas recidivantes.Material y métodos: Análisis retrospectivo de los pacientesdiagnosticados en nuestro centro de cicatriz queloidea, en los quese realizó braquiterapia coadyuvante, valorando su eficacia y suimplementación en nuestro protocolo de tratamiento de la cicatrizqueloidea. Resultados: Se estudiaron 4 pacientes entre 9-17 años con cicatricesqueloideas a nivel auricular, recidivantes a varias líneas terapéuticas,que fueron candidatos para el uso de braquiterapia coadyuvante, admi-nistrada posterior a la resección quirúrgica, en dos sesiones, se realizóseguimiento hasta 18-21 meses.Conclusiones: A pesar de nuestra limitada experiencia en el usode la braquiterapia coadyuvante, los resultados obtenidos hasta la fechaavalan su eficacia, de acuerdo con lo publicado en la literatura. Conside-ramos adecuada su inclusión en el tratamiento de cicatrices queloideasrecidivantes a otros tratamientos.(AU)


Objectives: The treatment of keloid scars is based on multiple linesof therapy, with varying levels of efficacy (1) , and there is currently nosingle treatment that guarantees cure and prevents recurrence. In thepediatric population, the treatments used are not standardized, and thereis insufficient evidence to support efficacy and complications. The objective of this study was to analyze the patients who required brachytherapyas an adjuvant to surgical resection in recurrent keloid scars.Materials and methods. A retrospective analysis of patients diagnosed with keloids and undergoing adjuvant brachytherapy in ourinstitution was carried out, while assessing efficacy and implementationin our treatment protocol for keloid scarring.Results: After various therapeutic lines, 4 patients aged 9-17 yearsold with recurrent keloid scars around the ear and eligible for adjuvantbrachytherapy – administered after surgical resection, in two sessions– were studied and followed up for up to 18-21 months.Conclusions: Despite our limited experience in the use of adjuvant brachytherapy, the results obtained to date support its efficacy,as reported in the literature. We therefore consider its inclusion in thetreatment of keloid scars that have recurred after other treatments tobe appropriate.(AU)


Subject(s)
Humans , Male , Female , Child , Adolescent , Cicatrix , Brachytherapy , Clinical Protocols , Treatment Outcome , Keloid/complications , Keloid/diagnostic imaging , Keloid/surgery , General Surgery , Pediatrics , Health Systems , Retrospective Studies
5.
Arch. esp. urol. (Ed. impr.) ; 75(6): 532-538, Aug. 28, 2022. tab, ilus
Article in Spanish | IBECS | ID: ibc-209633

ABSTRACT

Purpose: The diuretic renal scan (MAG3) continues being the gold standard to test the improvement of the urinary drainage after pyeloplasty. Recent researches suggest that there are certain parameters of ultrasound (US) that may indicate an adequate urinary drainage during the follow-up. Our aim is to prove if the measurement of the anteroposterior diameter (APD) of renal pelvis by USS after the pyeloplasty may be a valid screening method to select those patients who also require a MAG3. Methods: We retrospectively study the patients who underwent pyeloplasty between 2010 and 2019. The sample was divided in two groups depending of the increase or non-increase in the pelvic APD on postoperative US. The results of the MAG3 and the US of both groups were compared in relation to the presence or absence of obstruction and the need for repyeloplasty. Results: We included a total of 124 pyeloplasty, with a median age of 6 months (IQR 4–36); 12 patients showed an increase in pelvic APD, of those 5 had an obstructive MAG3 and renal function >10%, requiring reoperation. Of the 112 patients in whom the pelvic APD did not increase, only one patient needed reoperation due to obstruction in the MAG3, showing the same pre and postoperative pelvic APD. The sensitivity (S) of the US was 83.33% and the specificity (E) was 94.07%. Conclusion: A decrease of the renal pelvic APD between US before and after surgery appears to be enough to exclude those patients who will not to develop a recurrence of ureteropelvic junction obstruction (UPJO). In the rest of the patients, it would be necessary study the urinary drainage using MAG3, avoiding its inherent drawbacks in all patients undergoing pyeloplasty (AU)


Introducción: El renograma diurético (MAG3) continúa siendo la prueba principal para determinar la mejoradel drenaje urinario tras la pieloplastia. Trabajos recientessugieren que ciertos parámetros de la ecografía pueden indicar un adecuado drenaje urinario en el seguimiento. Nuestro objetivo es determinar si la medición del diámetro antero posterior (DAP) de la pelvis renal por ecografía trasla pieloplastia puede ser un método de cribado válido paraseleccionar a aquellos pacientes que requieren además unMAG3.Material y Métodos: Se llevó a cabo un estudio retrospectivo de los pacientes intervenidos mediante pieloplastiaentre los años 2010 y 2019. En todos se realizó ecografíay MAG3 pre y postoperatorio recogiendo diferentes datos.La muestra se dividió en dos grupos en relación al aumentoo no aumento del DAP de la pelvis en la ecografía postoperatoria. Los resultados de la ecografía y MAG3 de ambosgrupos se compararon en relación a la presencia o ausenciade obstrucción y la necesidad de reintervención. A su vezse calcularon la sensibilidad y especificidad de la ecografíaen relación al aumento del DAP de la pelvis.Resultados: Se incluyeron un total de 124 pieloplastias, con una mediana de edad de 6 meses (RIQ 4–36); 12pacientes mostraron un aumento del DAP de la pelvis, delos cuales el MAG3 fue obstructivo y con función renal>10% en 5, siendo necesario reintervención. De los 112pacientes en los que el DAP de la pelvis no aumentó, soloun paciente necesitó reintervención al tener obstrucción enel MAG3, mostrando un DAP de la pelvis pre y postoperatorio con el mismo valor. La sensibilidad de la ecografíafue de 83.33% y la especificidad de 94.07%.Conclusión: Una disminución en el DAP de la pelvisrenal entre la ecografía pre y postquirúrgica parece suficiente para descartar aquellos pacientes que no van a desarrollar una reestenosis de la unión ureteropélvica... (AU)


Subject(s)
Humans , Infant , Child, Preschool , Urologic Surgical Procedures/methods , Ureteral Obstruction/surgery , Hydronephrosis/surgery , Retrospective Studies , Treatment Outcome , Diuretics/therapeutic use , Follow-Up Studies
6.
Arch Virol ; 167(11): 2287-2292, 2022 Nov.
Article in English | MEDLINE | ID: mdl-35857148

ABSTRACT

Carrot virome analysis using high-throughput sequencing revealed the presence of two RNA molecules with properties of satellite RNAs that are homologous to the satellite RNA of cereal yellow dwarf virus-RPV (CYDV-RPV). Satellite 1 is 298 nt long, while satellite 2 is 368 nt long. Their positive and negative genome strands contain hammerhead ribozymes similar to those found in other self-cleaving satellite RNAs. While both satellites were detected in Spanish carrot populations, only satellite 2 was found in French carrot populations. The most likely helper virus for these two satellites is carrot red leaf virus (CtRLV), which, like CYDV-RPV, is a polerovirus.


Subject(s)
Daucus carota , Luteoviridae , RNA, Catalytic , Base Sequence , Luteoviridae/genetics , RNA, Catalytic/chemistry , RNA, Catalytic/genetics , RNA, Catalytic/metabolism , RNA, Satellite/genetics , RNA, Viral/chemistry , RNA, Viral/genetics , Virome
7.
Cir. pediátr ; 34(2): 183-187, Abr. 2021. ilus, tab
Article in Spanish | IBECS | ID: ibc-216661

ABSTRACT

Objetivos: El uso del inhibidor mTOR sirolimus ha supuesto unavance en el tratamiento de pacientes con anomalías vasculares complicadas. El objetivo de este estudio es presentar nuestra serie de pacientespediátricos con anomalías vasculares tratados con sirolimus oral y haceruna revisión de la literatura al respecto. Material y métodos: Se realizó un análisis retrospectivo de lospacientes con anomalías vasculares complicadas tratados con sirolimusoral en nuestro centro desde el año 2016. La dosis inicial utilizada fuede 0,8 mg/m2 cada 12 horas y el rango terapéutico de 5-15 ng/ml. Todos los pacientes recibieron profilaxis con trimetoprim-sulfametoxazol. Resultados: Se incluyeron seis niños, tres varones y tres mujeres, con una edad media al inicio del tratamiento de 9,5 años. Trespresentaban una malformación linfática en cabeza y cuello, dos unamalformación venosa en miembro inferior y la última una malformación combinada linfática-venosa a nivel toracoabdominal. Todos habíanrecibido múltiples tratamientos previos sin mejoría. Tras el inicio desirolimus, cinco pacientes mejoraron clínicamente (tiempo medio 3,6meses) y cuatro radiológicamente (tiempo medio 6,6 meses). Se registraron efectos adversos leves y transitorios en tres casos. Actualmente,cinco pacientes continúan con el tratamiento. Conclusiones: El sirolimus oral es un tratamiento eficaz y seguroen pacientes con anomalías vasculares complicadas. Nuestros resultadosapoyan su uso en malformaciones linfáticas y venosas en las que hanfracasado otros tratamientos, presentando buenas respuestas sintomáticasy, en menor medida, radiológicas.(AU)


Objective: Sirolimus mTOR inhibitor represents a major advancein the treatment of patients with complicated vascular abnormalities.The objective of this study was to present our series of pediatric patientswith vascular abnormalities treated with oral sirolimus, and to conducta review of the relevant literature. Materials and methods: A retrospective analysis of patients withcomplicated vascular abnormalities treated with oral sirolimus in ourhealthcare facility from 2016 was carried out. Initial dosage was 0.8 mg/m 2 every 12 hours, and therapeutic range was 5-15 ng/ml. All patientsreceived trimethoprim-sulfamethoxazole prophylaxis. Results: 6 children –3 boys and 3 girls– with a mean age of 9.5years at treatment initiation were included. 3 of them had head and necklymphatic malformation, 2 had lower limb venous malformation, and 1had combined lymphatic-venous malformation at the thoracoabdominal level. They all had received multiple previous treatments withoutimprovement. Following sirolimus initiation, 5 patients had clinicalimprovement (mean time: 3.6 months) and 4 had radiological improvement (mean time: 6.6 months). Mild and transitory adverse effects werenoted in the 3 cases. Today, 5 patients remain under treatment. Conclusions: Oral sirolimus is an effective and safe treatment inpatients with complicated vascular abnormalities. Our results supportsirolimus use in lymphatic and venous malformations in which previoustreatments have failed, with a good symptomatic and, to a lesser extent,radiological response.(AU)


Subject(s)
Humans , Male , Female , Child , Sirolimus , Vascular System Injuries , Sirolimus/antagonists & inhibitors , Blood Vessels/abnormalities , Pediatrics , Retrospective Studies
8.
Actas urol. esp ; 44(10): 659-664, dic. 2020. tab, graf
Article in Spanish | IBECS | ID: ibc-195508

ABSTRACT

INTRODUCCIÓN Y OBJETIVO: La coronavirus disease 2019 (COVID-19) ha ocasionado una pandemia de repercusión mundial que obligó a tomar medidas sociopolíticas, como la declaración del estado de alarma en España. Paralelamente se llevó a cabo la reestructuración de las actividades e infraestructuras médico-quirúrgicas pediátricas, con la consecuente suspensión de la actividad quirúrgica no urgente de Urología Pediátrica. Analizamos la repercusión de la pandemia COVID-19 sobre la actividad quirúrgica en una sección de Urología Pediátrica, así como las complicaciones quirúrgicas, según la clasificación de Clavien-Dindo. MATERIALES Y MÉTODOS: Se procedió a la revisión sistemática de los datos epidemiológicos, clínicos y quirúrgicos, incluyendo las complicaciones y reingresos de todos los pacientes intervenidos en la sección de Urología Pediátrica desde la declaración del estado de alarma hasta el levantamiento del mismo. Para su estudio se procedió a la división en cinco bloques temporales acorde a las fases de desescalada. RESULTADOS: Se realizaron 49 intervenciones quirúrgicas en 45 pacientes (ocho previos a la implantación de las fases de desescalada). La patología con prioridad alta fue la más frecuente en las primeras fases, siendo la estenosis de la unión pieloureteral (EPU) la más prevalente. Se registraron cuatro complicaciones (8,8%), ninguna de ellas de origen respiratorio. CONCLUSIONES: Las recomendaciones de la EAU para la reanudación de la actividad quirúrgica han permitido una correcta, segura y gradual transición al ritmo quirúrgico habitual en Urología Pediátrica. La clasificación de Clavien-Dindo es útil y válida para su aplicación en esta sección. No se han registrados complicaciones respiratorias que pudiesen ser atribuibles a la situación pandémica


INTRODUCTION AND OBJECTIVE: The coronavirus disease 2019 (COVID-19) has caused a pandemic of global impact that forced social-political measures to be taken, such as the declaration of the state of alarm in Spain. At the same time, the reorganization of the pediatric medical-surgical activities and infrastructures was carried out, with the consequent suspension of the non-urgent surgical activity of Pediatric Urology. We analyzed the impact of the COVID-19 pandemic on surgical activity in a Pediatric Urology division, as well as surgical complications according to the Clavien-Dindo classification. MATERIALS AND METHODS: A systematic review of epidemiological, clinical and surgical data was carried out, including complications and readmissions of all patients operated on in the division of Pediatric Urology within the duration of the state of alarm. Five time periods have been created according to the de-escalation phases. RESULTS: Forty-nine surgical procedures were carried out on 45 patients (8 prior to the implementation of the de-escalation phases). High priority pathologies were the most frequent in the first phases, being the ureteropelvic junction (UPJ) obstruction the most prevalent. Four complications were recorded (8.8%), none of them were respiratory. CONCLUSIONS: The EAU recommendations for the resumption of surgical activity have allowed a correct, safe and gradual transition to the routine surgical activity in Pediatric Urology. The Clavien-Dindo classification is useful and valid for application in this division. No respiratory complications have been reported that could be attributable to the pandemic situation


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Coronavirus Infections/epidemiology , Pandemics , Postoperative Complications/classification , Betacoronavirus , Urologic Surgical Procedures/adverse effects , Patient Readmission , Postoperative Complications/epidemiology , Prostatic Neoplasms/surgery , Prune Belly Syndrome/surgery , Retrospective Studies , Rhabdomyosarcoma, Embryonal/surgery , Urinary Bladder Neoplasms/surgery , Urologic Surgical Procedures/statistics & numerical data , Urology Department, Hospital , Spain/epidemiology
9.
Actas Urol Esp (Engl Ed) ; 44(10): 659-664, 2020 Dec.
Article in English, Spanish | MEDLINE | ID: mdl-33069488

ABSTRACT

INTRODUCTION AND OBJECTIVE: The coronavirus disease 2019 (COVID-19) has caused a pandemic of global impact that forced social-political measures to be taken, such as the declaration of the state of alarm in Spain. At the same time, the reorganization of the pediatric medical-surgical activities and infrastructures was carried out, with the consequent suspension of the non-urgent surgical activity of Pediatric Urology. We analyzed the impact of the COVID-19 pandemic on surgical activity in a Pediatric Urology division, as well as surgical complications according to the Clavien-Dindo classification. MATERIALS AND METHODS: A systematic review of epidemiological, clinical and surgical data was carried out, including complications and readmissions of all patients operated on in the division of Pediatric Urology within the duration of the state of alarm. Five time periods have been created according to the de-escalation phases. RESULTS: Forty-nine surgical procedures were carried out on 45 patients (8 prior to the implementation of the de-escalation phases). High priority pathologies were the most frequent in the first phases, being the ureteropelvic junction (UPJ) obstruction the most prevalent. Four complications were recorded (8.8%), none of them were respiratory. CONCLUSIONS: The EAU recommendations for the resumption of surgical activity have allowed a correct, safe and gradual transition to the routine surgical activity in Pediatric Urology. The Clavien-Dindo classification is useful and valid for application in this division. No respiratory complications have been reported that could be attributable to the pandemic situation.


Subject(s)
COVID-19/epidemiology , Pandemics , Postoperative Complications/epidemiology , SARS-CoV-2 , Urologic Surgical Procedures/adverse effects , Child , Child, Preschool , Female , Humans , Infant , Male , Patient Readmission/statistics & numerical data , Postoperative Complications/classification , Prostatic Neoplasms/surgery , Prune Belly Syndrome/surgery , Retrospective Studies , Rhabdomyosarcoma, Embryonal/surgery , Urinary Bladder Neoplasms/surgery , Urologic Surgical Procedures/statistics & numerical data , Urology Department, Hospital
10.
Cir Pediatr ; 33(4): 183-187, 2020 Oct 01.
Article in English, Spanish | MEDLINE | ID: mdl-33016658

ABSTRACT

OBJECTIVE: Sirolimus mTOR inhibitor represents a major advance in the treatment of patients with complicated vascular abnormalities. The objective of this study was to present our series of pediatric patients with vascular abnormalities treated with oral sirolimus, and to conduct a review of the relevant literature. MATERIAL AND METHODS: A retrospective analysis of patients with complicated vascular abnormalities treated with oral sirolimus in our healthcare facility from 2016 was carried out. Initial dosage was 0.8 mg/m2 every 12 hours, and therapeutic range was 5-15 ng/ml. All patients received trimethoprim-sulfamethoxazole prophylaxis. RESULTS: 6 children -3 boys and 3 girls- with a mean age of 9.5 years at treatment initiation were included. 3 of them had head and neck lymphatic malformation, 2 had lower limb venous malformation, and 1 had combined lymphatic-venous malformation at the thoracoabdominal level. They all had received multiple previous treatments without improvement. Following sirolimus initiation, 5 patients had clinical improvement (mean time: 3.6 months) and 4 had radiological improvement (mean time: 6.6 months). Mild and transitory adverse effects were noted in the 3 cases. Today, 5 patients remain under treatment. CONCLUSIONS: Oral sirolimus is an effective and safe treatment in patients with complicated vascular abnormalities. Our results support sirolimus use in lymphatic and venous malformations in which previous treatments have failed, with a good symptomatic and, to a lesser extent, radiological response.


OBJETIVOS: El uso del inhibidor mTOR sirolimus ha supuesto un avance en el tratamiento de pacientes con anomalías vasculares complicadas. El objetivo de este estudio es presentar nuestra serie de pacientes pediátricos con anomalías vasculares tratados con sirolimus oral y hacer una revisión de la literatura al respecto. MATERIAL Y METODOS: Se realizó un análisis retrospectivo de los pacientes con anomalías vasculares complicadas tratados con sirolimus oral en nuestro centro desde el año 2016. La dosis inicial utilizada fue de 0,8 mg/m2 cada 12 horas y el rango terapéutico de 5-15 ng/ml. Todos los pacientes recibieron profilaxis con trimetoprim-sulfametoxazol. RESULTADOS: Se incluyeron seis niños, tres varones y tres mujeres, con una edad media al inicio del tratamiento de 9,5 años. Tres presentaban una malformación linfática en cabeza y cuello, dos una malformación venosa en miembro inferior y la última una malformación combinada linfática-venosa a nivel toracoabdominal. Todos habían recibido múltiples tratamientos previos sin mejoría. Tras el inicio de sirolimus, cinco pacientes mejoraron clínicamente (tiempo medio 3,6 meses) y cuatro radiológicamente (tiempo medio 6,6 meses). Se registraron efectos adversos leves y transitorios en tres casos. Actualmente, cinco pacientes continúan con el tratamiento. CONCLUSIONES: El sirolimus oral es un tratamiento eficaz y seguro en pacientes con anomalías vasculares complicadas. Nuestros resultados apoyan su uso en malformaciones linfáticas y venosas en las que han fracasado otros tratamientos, presentando buenas respuestas sintomáticas y, en menor medida, radiológicas.


Subject(s)
Lymphatic Abnormalities/drug therapy , Sirolimus/administration & dosage , Vascular Malformations/drug therapy , Administration, Oral , Adolescent , Child , Child, Preschool , Female , Humans , Lymphatic Abnormalities/physiopathology , Male , Retrospective Studies , Sirolimus/adverse effects , Treatment Outcome , Vascular Malformations/physiopathology
11.
Cir. pediátr ; 33(4): 183-187, oct. 2020. ilus, tab
Article in Spanish | IBECS | ID: ibc-195129

ABSTRACT

OBJETIVOS: El uso del inhibidor mTOR sirolimus ha supuesto un avance en el tratamiento de pacientes con anomalías vasculares complicadas. El objetivo de este estudio es presentar nuestra serie de pacientes pediátricos con anomalías vasculares tratados con sirolimus oral y hacer una revisión de la literatura al respecto. MATERIAL Y MÉTODOS: Se realizó un análisis retrospectivo de los pacientes con anomalías vasculares complicadas tratados con sirolimus oral en nuestro centro desde el año 2016. La dosis inicial utilizada fue de 0,8 mg/m2 cada 12 horas y el rango terapéutico de 5-15 ng/ml. Todos los pacientes recibieron profilaxis con trimetoprim-sulfametoxazol. RESULTADOS: Se incluyeron seis niños, tres varones y tres mujeres, con una edad media al inicio del tratamiento de 9,5 años. Tres presentaban una malformación linfática en cabeza y cuello, dos una malformación venosa en miembro inferior y la última una malformación combinada linfática-venosa a nivel toracoabdominal. Todos habían recibido múltiples tratamientos previos sin mejoría. Tras el inicio de sirolimus, cinco pacientes mejoraron clínicamente (tiempo medio 3,6 meses) y cuatro radiológicamente (tiempo medio 6,6 meses). Se registraron efectos adversos leves y transitorios en tres casos. Actualmente, cinco pacientes continúan con el tratamiento. CONCLUSIONES: El sirolimus oral es un tratamiento eficaz y seguro en pacientes con anomalías vasculares complicadas. Nuestros resultados apoyan su uso en malformaciones linfáticas y venosas en las que han fracasado otros tratamientos, presentando buenas respuestas sintomáticas y, en menor medida, radiológicas


OBJECTIVE: Sirolimus mTOR inhibitor represents a major advance in the treatment of patients with complicated vascular abnormalities. The objective of this study was to present our series of pediatric patients with vascular abnormalities treated with oral sirolimus, and to conduct a review of the relevant literature. MATERIALS AND METHODS: A retrospective analysis of patients with complicated vascular abnormalities treated with oral sirolimus in our healthcare facility from 2016 was carried out. Initial dosage was 0.8 mg/m2 every 12 hours, and therapeutic range was 5-15 ng/ml. All patients received trimethoprim-sulfamethoxazole prophylaxis. RESULTS: 6 children -3 boys and 3 girls- with a mean age of 9.5 years at treatment initiation were included. 3 of them had head and neck lymphatic malformation, 2 had lower limb venous malformation, and 1 had combined lymphatic-venous malformation at the thoracoabdominal level. They all had received multiple previous treatments without improvement. Following sirolimus initiation, 5 patients had clinical improvement (mean time: 3.6 months) and 4 had radiological improve-ment (mean time: 6.6 months). Mild and transitory adverse effects were noted in the 3 cases. Today, 5 patients remain under treatment. CONCLUSIONS: Oral sirolimus is an effective and safe treatment in patients with complicated vascular abnormalities. Our results support sirolimus use in lymphatic and venous malformations in which previous treatments have failed, with a good symptomatic and, to a lesser extent, radiological response


Subject(s)
Humans , Male , Female , Child, Preschool , Child , Lymphatic Abnormalities/drug therapy , Vascular Malformations/drug therapy , Sirolimus/administration & dosage , Lymphatic Abnormalities/diagnostic imaging , Vascular Malformations/diagnostic imaging , Head/abnormalities , Head/blood supply , Neck/abnormalities , Neck/blood supply , Retrospective Studies , Trimethoprim, Sulfamethoxazole Drug Combination/administration & dosage
12.
Actas urol. esp ; 44(7): 450-457, sept. 2020. tab
Article in Spanish | IBECS | ID: ibc-192541

ABSTRACT

La pandemia COVID-19 causada por el virus SARS-CoV-2 ha ocasionado decenas de miles de muertos en España y logrado colapsar los hospitales de la red sanitaria en la Comunidad de Madrid, debido en gran parte a su particular tendencia a causar neumonías graves con necesidad de soporte ventilatorio. Este hecho ha ocasionado el colapso de nuestro centro, llegando a tener una ocupación del 130% de sus camas por enfermos COVID-19, y causando por tanto el cese absoluto de actividad del servicio de urología, la práctica desaparición de la docencia de los residentes y la incorporación de buena parte de la plantilla de urología al grupo de personal médico que atiende a estos pacientes. Para la recuperación de esta elevada cantidad de actividad suspendida será necesaria una priorización de la patología en base a criterios puramente clínicos, para la cual se proponen tablas que recogen la relevancia de cada patología dentro de cada área de la urología. Herramientas brindadas por la tecnología como la formación online o los simuladores quirúrgicos podrán ser útiles para la necesaria restitución de la formación de residentes


The COVID-19 pandemic caused by the SARS-CoV-2 virus has caused tens of thousands of deaths in Spain and has managed to breakdown the healthcare system hospitals in the Community of Madrid, largely due to its tendency to cause severe pneumonia, requiring ventilatory support. This fact has caused our center to collapse, with 130% of its beds occupied by COVID-19 patients, thus causing the absolute cessation of activity of the urology service, the practical disappearance of resident training programs, and the incorporation of a good part of the urology staff into the group of medical personnel attending these patients. In order to recover from this extraordinary level of suspended activity, we will be obliged to prioritize pathologies based on purely clinical criteria, for which tables including the relevance of each pathology within each area of urology are being proposed. Technology tools such as online training courses or surgical simulators may be convenient for the necessary reestablishment of resident education


Subject(s)
Humans , Coronavirus Infections/epidemiology , Pneumonia, Viral/epidemiology , Betacoronavirus , Pandemics , Health Priorities , Triage , Urology Department, Hospital/organization & administration , Urology Department, Hospital/statistics & numerical data
13.
Actas Urol Esp (Engl Ed) ; 44(7): 450-457, 2020 Sep.
Article in Spanish | MEDLINE | ID: mdl-32456883

ABSTRACT

The COVID-19 pandemic caused by the SARS-CoV-2 virus has caused tens of thousands of deaths in Spain and has managed to breakdown the healthcare system hospitals in the Community of Madrid, largely due to its tendency to cause severe pneumonia, requiring ventilatory support. This fact has caused our center to collapse, with 130% of its beds occupied by COVID-19 patients, thus causing the absolute cessation of activity of the urology service, the practical disappearance of resident training programs, and the incorporation of a good part of the urology staff into the group of medical personnel attending these patients. In order to recover from this extraordinary level of suspended activity, we will be obliged to prioritize pathologies based on purely clinical criteria, for which tables including the relevance of each pathology within each area of urology are being proposed. Technology tools such as online training courses or surgical simulators may be convenient for the necessary reestablishment of resident education.


Subject(s)
Bed Occupancy/statistics & numerical data , Betacoronavirus , Coronavirus Infections/epidemiology , Pneumonia, Viral/epidemiology , Urology Department, Hospital/statistics & numerical data , Urology/statistics & numerical data , Ambulatory Care/statistics & numerical data , Bed Conversion/statistics & numerical data , COVID-19 , Coronavirus Infections/therapy , Humans , Internship and Residency , Pandemics , Patient Care Team/organization & administration , Patient Isolation , Pneumonia, Viral/therapy , SARS-CoV-2 , Spain/epidemiology , Urologic Surgical Procedures/statistics & numerical data , Urologists/supply & distribution , Urology/education , Urology/organization & administration , Urology Department, Hospital/organization & administration , Ventilators, Mechanical , Withholding Treatment/statistics & numerical data
14.
Acta pediatr. esp ; 78(3/4): e96-e100, mar.-abr. 2020. ilus, tab
Article in Spanish | IBECS | ID: ibc-202687

ABSTRACT

INTRODUCCIÓN: La invaginación intestinal representa la causa más frecuente de obstrucción intestinal entre los 6 meses y los 3 años, siendo secundaria en el 0,3-20% de los casos. El divertículo de Meckel es una causa común de invaginación secundaria y su tratamiento es fundamentalmente quirúrgico. MATERIAL Y MÉTODOS: Se revisaron retrospectivamente los casos codificados como invaginación intestinal en el Servicio de Urgencias Pediátricas del Hospital 12 de Octubre de Madrid entre 2013 y 2018. Se incluyeron 130 pacientes. RESULTADOS: En 10 de los 130 pacientes se identificó una causa subyacente: 5 linfomas intestinales, 4 divertículos de Meckel y 1 quiste de duplicación intestinal. Los casos secundarios fueron más frecuentes en varones (4:1), niños mayores de 3 años (60%) e invaginación ileocólica (90%). La invaginación por divertículo de Meckel afectó a 4 niños, 3 varones y 1 mujer, de entre 1 y 4 años. La ecografía diagnosticó la invaginación en los cuatro casos, pero sólo en uno sugirió divertículo de Meckel. En todos los casos, el tratamiento quirúrgico requerido incluyó reducción manual de la invaginación, seguida de diverticulectomía o resección intestinal más anastomosis. CONCLUSIONES: Las invaginaciones secundarias son más frecuentes en niños mayores de 3 años y en quienes fracasa el tratamiento conservador. El divertículo de Meckel es una de las causas más comunes de invaginación secundaria, sus manifestaciones clínicas son inespecíficas y su diagnóstico preoperatorio sigue suponiendo un reto en la actualidad. La utilidad del abordaje laparoscópico/laparoasistido en el tratamiento de las invaginaciones aún es limitada


INTRODUCTION: Intussusception is the most common cause of intestinal obstruction between 6 months and 3 years, having a pathological lead point in 0,3-20% of cases. Meckel's diverticulum is a frequent cause of secondary intussusception, which treatment is mostly surgical. METHODS: This work is a retrospective review of 130 patients diagnosed as intussusceptions. The samples were taken between 2013 and 2018, at the Department of Pediatric Emergency from the Hospital 12 de Octubre (Madrid). RESULTS: Pathological lead point was identified in ten cases (out of 130 patients): 5 intestinal lymphomas, 4 Meckel's diverticulums and 1 intestinal duplication cyst. Secondary intussusception was more common in males (4:1); children older than 3 years (60%); and patients with ileocolic intussusception (90%). Meckel's diverticulum affected 4 children between 1 to 4 years old, 3 males and 1 female. All were diagnosed for the intestinal invagination by ultrasound, but only in one case it suggested Meckel's diverticulum. Required surgical treatment always included manual reduction of intussusceptions, followed of diverticulectomy or intestinal resection plus anastomosis. CONCLUSIONS: Secondary intussusception is more common in children older than 3 years where conservative treatment fails. Meckel's diverticulum is one of the most common causes of secondary invagination, its clinical manifestations are not specific and, at present, its preoperative diagnosis is challenging. Currently, the use of the laparoscopic/laparoassisted approach is limited for the treatment of invaginations


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Meckel Diverticulum/complications , Intussusception/etiology , Meckel Diverticulum/surgery , Intussusception/surgery , Age Factors , Retrospective Studies
15.
Actas Urol Esp ; 44(7): 450-457, 2020 Sep.
Article in Spanish | MEDLINE | ID: mdl-38620218

ABSTRACT

The COVID-19 pandemic caused by the SARS-CoV-2 virus has caused tens of thousands of deaths in Spain and has managed to breakdown the healthcare system hospitals in the Community of Madrid, largely due to its tendency to cause severe pneumonia, requiring ventilatory support. This fact has caused our center to collapse, with 130% of its beds occupied by COVID-19 patients, thus causing the absolute cessation of activity of the urology service, the practical disappearance of resident training programs, and the incorporation of a good part of the urology staff into the group of medical personnel attending these patients. In order to recover from this extraordinary level of suspended activity, we will be obliged to prioritize pathologies based on purely clinical criteria, for which tables including the relevance of each pathology within each area of urology are being proposed. Technology tools such as online training courses or surgical simulators may be convenient for the necessary reestablishment of resident education.

16.
Actas urol. esp ; 44: 0-0, 2020. tab
Article in Spanish | IBECS | ID: ibc-187879

ABSTRACT

La pandemia COVID-19 causada por el virus SARS-CoV-2 ha causado decenas de miles de muertos en España y logrado colapsar los hospitales de la red sanitaria en la Comunidad de Madrid, debido en gran parte a su particular tendencia a causar neumonías graves con necesidad de soporte ventilatorio. Este hecho ha ocasionado el colapso de nuestro centro, llegando a tener una ocupación del 130% de sus camas por enfermos COVID-19, y causando por tanto el cese absoluto de actividad del servicio de urología, la práctica desaparición de la docencia de los residentes y la incorporación de buena parte de la plantilla de urología al grupo de personal médico que atiende a estos pacientes. Para la recuperación de esta elevada cantidad de actividad suspendida será necesaria una priorización de la patología en base a criterios puramente clínicos, para la cual se proponen tablas que recogen la relevancia de cada patología dentro de cada área de la urología. Herramientas brindadas por la tecnología como la formación online o los simuladores quirúrgicos podrán ser útiles para la necesaria restitución de la formación de residentes


The COVID-19 pandemic caused by the SARS-CoV-2 virus has caused tens of thousands of deaths in Spain and has managed to breakdown the healthcare system hospitals in the Community of Madrid, largely due to its tendency to cause severe pneumonia, requiring ventilatory support. This fact has caused our center to collapse, with 130% of its beds occupied by COVID-19 patients, thus causing the absolute cessation of activity of the urology service, the practical disappearance of resident training programs, and the incorporation of a good part of the urology staff into the group of medical personnel attending these patients. In order to recover from this extraordinary level of suspended activity, we will be obliged to prioritize pathologies based on purely clinical criteria, for which tables including the relevance of each pathology within each area of urology are being proposed. Technology tools such as online training courses or surgical simulators may be convenient for the necessary reestablishment of resident education


Subject(s)
Humans , Urology Department, Hospital/standards , Coronavirus Infections/epidemiology , Pneumonia, Viral/epidemiology , Pandemics , Tertiary Care Centers/standards , Urologic Surgical Procedures/statistics & numerical data , Health Services Needs and Demand/standards , Spain/epidemiology , Remote Consultation , Triage
17.
Actas urol. esp ; 43(7): 384-388, sept. 2019. ilus, graf
Article in Spanish | IBECS | ID: ibc-192176

ABSTRACT

Introducción: El abanico de indicaciones del tratamiento endoscópico del reflujo vesicoureteral (RVU) se abre cada vez más hasta incluir la corrección del reflujo secundario tras cirugía de reimplante ureteral. No obstante, este escenario supone un reto técnico debido a los cambios posquirúrgicos. El objetivo de este trabajo es presentar nuestra experiencia en el tratamiento endoscópico del RVU en unidades ureterales con reimplante tipo Cohen, con especial interés en las particularidades técnicas del procedimiento. Material y métodos: Se ha realizado un estudio retrospectivo de casos de RVU secundario tras cirugía de reimplante tratados mediante inyección subureteral. Técnica: Se coloca la aguja perpendicular al trayecto submucoso y se inyecta medial al orificio, formándose un habón en la cara anterior que ocluya el meato. Resultados: En el periodo comprendido entre 1993 y 2016 se realizaron 21 inyecciones sobre 15 unidades ureterales. La afección ureteral incluía el RVU primario (4), sistema dúplex con RVU al pielón inferior (4), megauréter (3) y ureterocele (2). La edad media de los pacientes fue de 5,7 años (rango: 2-12 años). El éxito se logró en 10 unidades ureterales (66,67%), disminución del grado de RVU en 4 (26,67%) y persistencia/no resolución en un caso (6,67%). Discusión: El mecanismo antirreflujo del reimplante depende de optimizar el trayecto submucoso. Este subgrupo de pacientes es pequeño y los estudios son escasos lo que dificulta el acuerdo sobre la técnica más adecuada. Conclusión: El tratamiento endoscópico del reflujo secundario tras cirugía de reimplante transtrigonal es un procedimiento con cierta particularidad técnica, pero seguro y eficaz que ofrece una alternativa previa a la reintervención quirúrgica


Introduction: The range of indications for endoscopic treatment of vesicoureteral reflux opens more and more until including correction of secondary reflux (VUR) after ureteral reimplantation. However these cases suppose a technical challenge due to postoperative changes. The aim of this work is to present our experience on endoscopic treatment for VUR in ureteral units with Cohen reimplantation surgery, with special interest in the technical peculiarities of the procedure. Material and methods: A retrospective study of cases of secondary VUR after reimplantation surgery treated by subureteral injection. Technique: We put the needle perpendicular to submucous tunnel and inject medially to hole forming a wheal on the anterior face that occludes the meatus. Results: During the 1993-2016 period 21 injections were performed in 15 ureteral units. The ureteral pathology included primary VUR (4), duplex system with lower pole reflux (4), megaureter (3) and ureterocele (2). Average patient age was 5.7 years old (2-12). Succesful outcome had been got in 10 ureteral units (66.67%), a decrease of VUR grade in 4 (26.67%) and perseverance/no resolution of grade IV VUR in 1 (6.67%). Discussion: The anti-reflux mechanism of reimplantation depends on optimizing the submucosous tunnel. This subgroup of pacients is small and there are few studies, hindering the agreement on the most appropiate technique. Conclusion: Endoscopic treatment of secondary reflux after reimplantation surgery is a procedure with certain technical feature, but safe and effective offering an alternative prior to surgical reoperation


Subject(s)
Humans , Male , Female , Child, Preschool , Child , Vesico-Ureteral Reflux/surgery , Treatment Outcome , Retrospective Studies , Endoscopy
18.
Actas Urol Esp (Engl Ed) ; 43(7): 384-388, 2019 Sep.
Article in English, Spanish | MEDLINE | ID: mdl-31103394

ABSTRACT

INTRODUCTION: The range of indications for endoscopic treatment of vesicoureteral reflux opens more and more until including correction of secondary reflux (VUR) after ureteral reimplantation. However these cases suppose a technical challenge due to postoperative changes. The aim of this work is to present our experience on endoscopic treatment for VUR in ureteral units with Cohen reimplantation surgery, with special interest in the technical peculiarities of the procedure. MATERIAL AND METHODS: A retrospective study of cases of secondary VUR after reimplantation surgery treated by subureteral injection. TECHNIQUE: We put the needle perpendicular to submucous tunnel and inject medially to hole forming a wheal on the anterior face that occludes the meatus RESULTS: During the 1993-2016 period 21 injections were performed in 15 ureteral units. The ureteral pathology included primary VUR (4), duplex system with lower pole reflux (4), megaureter (3) and ureterocele (2). Average patient age was 5.7 years old (2-12). Succesful outcome had been got in 10 ureteral units (66.67%), a decrease of VUR grade in 4 (26.67%) and perseverance/no resolution of grade IV VUR in 1 (6.67%) DISCUSSION: The anti-reflux mechanism of reimplantation depends on optimizing the submucosous tunnel. This subgroup of pacients is small and there are few studies, hindering the agreement on the most appropiate technique. CONCLUSION: Endoscopic treatment of secondary reflux after reimplantation surgery is a procedure with certain technical feature, but safe and effective offering an alternative prior to surgical reoperation.


Subject(s)
Replantation/methods , Ureter/surgery , Ureteroscopy , Vesico-Ureteral Reflux/surgery , Child , Child, Preschool , Female , Humans , Male , Retrospective Studies , Urologic Surgical Procedures/methods
19.
Acta pediatr. esp ; 76(11/12): e161-e163, nov.-dic. 2018. ilus
Article in Spanish | IBECS | ID: ibc-177428

ABSTRACT

Introducción: Los pólipos ureterales constituyen una causa poco frecuente de hidronefrosis en los niños. Presentamos un caso tratado en nuestro centro y realizamos una revisión de la literatura. Caso clínico: Varón de 5 años derivado a nuestra consulta por presentar episodios de dolor cólico en el flanco izquierdo. La ecografía mostró una hidronefrosis izquierda de grado II/IV, y el renograma con MAG-3 una curva de eliminación en la pelvis renal de tipo IIIb. Debido a la persistencia de la sintomatología, se decidió instaurar tratamiento quirúrgico, durante el cual se constató la presencia de pólipos fibroepiteliales en la pelvis renal que justificaban la sintomatología. Conclusión: El tratamiento de los pólipos ureterales en los niños presenta altas tasas de éxito; sin embargo, la inespecificidad de su presentación clínica, así como la dificultad de interpretación de las pruebas diagnósticas, pueden conllevar un importante retraso en el diagnóstico que afecte a la función renal


Introduction: Ureteral polyps are a strange cause of hydronephrosis in children. We report a case of a child treated in our hospital, and review of the related literature. Clinical case: A 5-year-old boy presented with severe, colicky, left lumbar pain. Renal ultrasound showed grade II/IV hydronephrosis, and the 99 m-Tc MAG-3 scan showed an obstructive drainage curve type IIIb. As the symptoms persisted, we decided surgical treatment, finding pyelic fibroepithelial polyps as the cause of the pain. Conclusion: Fibroepithelial polyp treatment in children is highly effective; nevertheless, the interpretation of diagnostic tests can be difficult, delaying the diagnosis and causing affectation of renal function


Subject(s)
Humans , Male , Child , Polyps/complications , Polyps/diagnosis , Hydronephrosis/etiology , Ureteral Obstruction/complications , Hydronephrosis/therapy , Urethra/diagnostic imaging , Urethra/pathology , Urethral Diseases/pathology , Pelvis/diagnostic imaging , Urography , Diagnosis, Differential
20.
Cir Pediatr ; 31(4): 171-175, 2018 Oct 17.
Article in Spanish | MEDLINE | ID: mdl-30371028

ABSTRACT

AIM OF STUDY: To describe our experience in the management of non-tuberculosis mycobacterial lymphadenitits (NTML). METHODS: Retrospective analysis of patients who underwent surgery for NTML in our centre during the period between 2010-2017. Demographic data, diagnostic tests, treatment and follow up information were recovered from medical records. RESULTS: 65 patients (26 male/39 female) with a mean age of 31 months (range 7 months-12 years) were intervened during the period of study. As diagnostic tests, chest X-ray was performed in 92.3% of patients with normal result in all cases, Mantoux test was positive in 20.3%, inconclusive in 12.5% and negative in 67.1%. Preoperative fine needle aspiration was positive for NTML (granulomatous necrotizing lymphadenitis) in 93.7% whereas culture for mycobacteria was only positive in 23.4% of cases, being Mycobacterium lentiflavum the most frequent agent found. Mean preoperative waiting time was 2.5 months with 7.7% of fistulization previous to surgery. Mean hospital stay was 1,1 days and there were no intraoperative complications. Mean follow up time was 5.5 months (range 1-24 months) during which 19 cases of temporal facial paralysis were noted, among which only 2 persisted after one year. CONCLUSIONS: NTML is a disease with a growing incidence in our country. It is important to make an early diagnosis and surgical treatment in order to avoid complications, as surgery has demonstrated to be safe and effective, with a low rate of complications. We believe the actual protocols should be revised/checked due to low effectiveness of diagnostic tests.


OBJETIVOS: Describir nuestra experiencia en el manejo de la linfadenitis por micobacterias no tuberculosas (LMNT). MATERIAL Y METODOS: Análisis retrospectivo de 65 pacientes (26 varones/ 39 mujeres) intervenidos en nuestro centro de LMNT durante los años 2010-2017. Se analizaron datos demográficos, pruebas complementarias realizadas y datos de seguimiento. RESULTADOS: La edad media fue de 31 meses (rango 7 meses-12 años). Para el diagnóstico la radiografía de tórax se realizó al 92,3% de pacientes, siendo en todos normal. El Mantoux fue positivo en 20,3%, dudoso en 12,5% y negativo en 67,1%. La PAAF preoperatoria fue diagnóstica (linfadenitis granulomatosa necrotizante) en 93,7% mientras que el cultivo para micobacterias fue positivo solo en 23,4%, siendo el Mycobacterium lentiflavum el patógeno más frecuentemente encontrado. El tiempo de espera preoperatorio fue de 2,5 meses con un porcentaje de fistulización previo a la cirugía de 7,7%. La estancia hospitalaria media fue 1,1 días y no hubo complicaciones perioperatorias. El tiempo medio de seguimiento fue 5,5 meses (rango 1-24 meses) observándose 19 casos de parálisis facial temporal, de los cuales 2 persistieron al cabo de 1 año. CONCLUSIONES: La LMNT es una enfermedad cada vez más frecuente en nuestro medio. Es importante realizar un diagnóstico y tratamiento precoz, puesto que el tratamiento quirúrgico ha demostrado ser seguro y eficaz asociando baja tasa de complicaciones. Creemos que los protocolos actuales se deben revisar, debido a la escasa rentabilidad de algunas pruebas complementarias.


Subject(s)
Lymphadenitis/surgery , Mycobacterium Infections, Nontuberculous/surgery , Nontuberculous Mycobacteria/isolation & purification , Biopsy, Fine-Needle/methods , Child , Child, Preschool , Facial Paralysis/epidemiology , Facial Paralysis/etiology , Female , Follow-Up Studies , Humans , Infant , Length of Stay , Lymphadenitis/diagnosis , Lymphadenitis/microbiology , Male , Mycobacterium Infections, Nontuberculous/diagnosis , Mycobacterium Infections, Nontuberculous/microbiology , Retrospective Studies , Time Factors
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