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1.
Zhongguo Zhong Yao Za Zhi ; 18(4): 212-4, 253-4, 1993 Apr.
Article in Chinese | MEDLINE | ID: mdl-8216784

ABSTRACT

Experimental results showed that the original contents of chemical constituents in the new processed products were higher than those in the old one, while the content of assistant alum in the new products was lower than that of the old one. It is thus confirmed that the new processing technology is reasonable.


Subject(s)
Amino Acids/analysis , Drugs, Chinese Herbal/chemistry , Oleic Acids/analysis , Sitosterols/analysis , Hot Temperature , Technology, Pharmaceutical
2.
Zhongguo Yao Li Xue Bao ; 10(6): 554-6, 1989 Nov.
Article in Chinese | MEDLINE | ID: mdl-2534936

ABSTRACT

Seminiferous epithelial cells of mouse testis were treated with hematoporphyrin derivative (HPD)-light in vitro. After HPD-light treatment, the changes within cells in early stage of prophase were observed. Examination with EM showed that 30 min after HPD-light treatment, the mitochondria were aggregated and vesiculated, the nucleus showed an irregular outline and a sign of chromatolysis; the other organelles showed no significant changes at this time. The results suggest that both mitochondria and nucleus are susceptible to HPD-light treatment. Three hours after HPD-light treatment, many of multi-nucleated spermatids appeared and they all contained deformed nuclei. This fact suggests that cytokinesis was inhibited by this treatment, and the chromatin of metaphase were also damage.


Subject(s)
Hematoporphyrin Photoradiation , Hematoporphyrins/pharmacology , Photochemotherapy , Radiation-Sensitizing Agents/pharmacology , Seminiferous Epithelium/drug effects , Testis/drug effects , Animals , Cell Nucleus/ultrastructure , Hematoporphyrin Derivative , Male , Mice , Microscopy, Electron , Mitochondria/ultrastructure , Organelles/ultrastructure , Seminiferous Epithelium/cytology
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