[Premalignant lesions of the penis]. / Lesiones premalignas del pene.

The dermatological conditions that affect the penis are diverse, and may be typical of this area or be part of systemic diseases. The anamnesis and inspection are often sufficient for diagnosis, but other times, it is difficult to distinguish between benign dermatoses and premalignant lesions. The delay in consulting, due to fear, shame or the doctor's own ignorance, can cause the lesions to progress to malignancy and require aggressive treatments that can alter the quality of life and physical and mental health of the patient. We must suspect premalignancy or malignancy any lesion of the penis that is not modified with specific or empirical treatment and refer for biopsy. HPV infections are the origin of 50% of premalignant lesions. After treatment and due to possible relapses and progression to infiltrating carcinomas, a strict follow-up plan is necessary.

[Numb chin syndrome as a sign of tumour recurrence]. / Síndrome del mentón entumecido como manifestación de recidiva tumoral.

Numb chin syndrome is characterized by anaesthesia or paraesthesia in the areas supplied by the chin nerve. It is a rare symptom which tends to be underestimated. Far from being insignificant, it should be taken as an indication of hidden malignant disease. In patients previously diagnosed with neoplasia, it is frequently associated with ominous diagnosis indicating rapid progression of the disease. This paper reports the case of a patient diagnosed with breast cancer 20 years earlier who presents chin numbness. Further tests confirm the suspicion of metastatic disease (meningeal carcinomatosis and multiple bone and pulmonary metastases) leading to death two months after the initial consultation.

Síndrome del mentón entumecido como manifestación de recidiva tumoral / Numb chin syndrome as a sign of tumour recurrence

El síndrome del mentón entumecido se caracteriza por la hipo o anestesia de la región inervada por el nervio mentoniano. Es un síntoma poco frecuente y en gran medida subestimado. Lejos de considerarlo un síntoma banal, su presencia debe alertar al clínico como posible manifestación de una enfermedad maligna oculta. En pacientes previamente diagnosticados de una neoplasia, representa a menudo un síntoma ominoso que indica mal pronóstico por el rápido progreso de la enfermedad. Presentamos el caso de una paciente diagnosticada de cáncer de mama 20 años atrás, que consulta por adormecimiento del mentón. Los estudios complementarios confirman la sospecha de enfermedad metastásica (carcinomatosis meníngea y múltiples metástasis óseas y pulmonares) falleciendo a los 2 meses de haber consultado (AU)

Numb chin syndrome is characterized by anaesthesia or paraesthesia in the areas supplied by the chin nerve. It is a rare symptom which tends to be underestimated. Far from being insignificant, it should be taken as an indication of hidden malignant disease. In patients previously diagnosed with neoplasia, it is frequently associated with ominous diagnosis indicating rapid progression of the disease. This paper reports the case of a patient diagnosed with breast cancer 20 years earlier who presents chin numbness. Further tests confirm the suspicion of metastatic disease (meningeal carcinomatosis and multiple bone and pulmonary metastases) leading to death two months after the initial consultation (AU)

[Multiple familial osteochondromatosis: presentation of a case]. / Osteocondromatosis múltiple familiar: a propósito de un caso.

Enchondromas are benign cartilage tumours that grow slowly in the bone metaphysis. They may involve solitary or multiple lesions. Enchondromatoses include a heterogeneous group of hardly distinguishable syndromes characterised by the presence of multiple enchondromas that may cause musculoskeletal malformations (secondary to limb shortening), scoliosis, pathological fractures, or pseudoarthrosis. The most dreaded complication, osteochondrosarcoma, occurs in up to 25% of patients. We present the case of a 67-year-old male with no previous diagnosis, requiring attention due to the appearance of a painful tumour in his left hip which degenerated rapidly over the past year. Family history and clinical-radiological data confirmed the diagnosis of Multiple Familial Osteochondromatosis. Although clinical evolution and imaging led to suspect a malignant degeneration (osteochondrosarcoma), this was not confirmed by the histopathological study of the surgical sample.

Osteocondromatosis múltiple familiar: a propósito de un caso / Multiple familial osteochondromatosis: presentation of a case

Los encondromas son tumores benignos de cartílago que crecen de forma lenta en las metáfisis de los huesos. Pueden ser lesiones solitarias o múltiples. Las encondromatosis comprenden un grupo heterogéneo de síndromes, difíciles de diferenciar, caracterizados por la presencia de múltiples encondromas que pueden llegar a producir malformaciones musculoesqueléticas (secundarias al acortamiento de extremidades), escoliosis, fracturas patológicas o seudoartrosis. La complicación más temida, el osteocondrosarcoma, puede acontecer hasta en el 25% de los pacientes. Exponemos el caso de un varón de 67 años, sin diagnósticos previos conocidos, que consulta por la aparición en cadera izquierda de una tumoración dolorosa y rápidamente deformante en el último año. Los antecedentes familiares y los datos clínico-radiológicos confirmaron el diagnóstico de osteocondromatosis múltiple familiar. Aun cuando la evolución clínica y los estudios de imagen hicieron sospechar una degeneración maligna (osteocondrosarcoma), esta no se confirmó en el estudio histopatológico de la pieza quirúrgica (AU)

Enchondromas are benign cartilage tumours that grow slowly in the bone metaphysis. They may involve solitary or multiple lesions. Enchondromatoses include a heterogeneous group of hardly distinguishable syndromes characterised by the presence of multiple enchondromas that may cause musculoskeletal malformations (secondary to limb shortening), scoliosis, pathological fractures, or pseudoarthrosis. The most dreaded complication, osteochondrosarcoma, occurs in up to 25% of patients. We present the case of a 67-year-old male with no previous diagnosis, requiring attention due to the appearance of a painful tumour in his left hip which degenerated rapidly over the past year. Family history and clinical-radiological data confirmed the diagnosis of Multiple Familial Osteochondromatosis. Although clinical evolution and imaging led to suspect a malignant degeneration (osteochondrosarcoma), this was not confirmed by the histopathological study of the surgical sample (AU)