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1.
J Mot Behav ; : 1-11, 2024 May 29.
Article in English | MEDLINE | ID: mdl-38811009

ABSTRACT

Attention Deficit Hyperactivity Disorder (ADHD) is characterized by inappropriate levels of activity, impulsivity, and inattention. Developmental Coordination Disorder (DCD) is a condition involving challenges in acquiring and executing motor skills. This cross-sectional study aimed to distinguish motor symptoms between ADHD and ADHD/DCD. A total of 283 children from two elementary schools underwent screening, leading to the identification of 27 children with ADHD. The assessment encompassed the Swanson, Nolan, and Pelham-IV Questionnaire (SNAP-IV), the Movement Assessment Battery for Children (MABC-2), and the Motor Development Scale (MDS). The groups consisted of ADHD (14) and ADHD/DCD (13). Statistical analysis revealed significant differences in general motor age means between groups (p = 0.016), indicating inferior performance in the ADHD/DCD group. The coexistence of DCD significantly influenced the motor performance of children with ADHD, particularly in fine motor skills (p = 0.018) and balance (p = 0.033). Both groups exhibited mild to moderate risk of motor development delay. It is suggested that ADHD is associated with motor problems, even when DCD is not co-occurring. Specific domain-based analysis could demonstrate how the co-occurrence with DCD affects the motor performance of children with ADHD, with statistically significant differences observed in fine motor skills and balance.

2.
Pediatr Phys Ther ; 35(2): 202-210, 2023 04 01.
Article in English | MEDLINE | ID: mdl-36867588

ABSTRACT

PURPOSE: To summarize and update the current knowledge on the effectiveness of hippotherapy on postural control in children with cerebral palsy. METHODS: Using a systematic review methodology, the electronic databases PubMed, Virtual Health Library, PEDro, Scielo, Embase, and Web of Science were searched for eligible articles from 2011 up to September 2021. Quality assessment of eligible studies was performed using the PEDro scale. RESULTS: There were 239 identified studies. Eight clinical trials were selected. The total sample consisted of 264 individuals, with 134 allocated to the experimental group (hippotherapy) and 130 individuals to the control group (conventional therapy). Most studies had moderate to high methodological quality. CONCLUSIONS: Hippotherapy can be an effective intervention to improve several aspects related to postural control, such as static balance (especially in the sitting posture), dynamic balance, and alignment (body posture) in children aged 3 to 16 years, particularly with spastic hemiplegia or diplegia. WHAT THIS ADDS TO THE EVIDENCE: This review summarizes studies that explore potential effects of hippotherapy on postural control in children with cerebral palsy.


Subject(s)
Cerebral Palsy , Equine-Assisted Therapy , Humans , Child , Cerebral Palsy/rehabilitation , Equine-Assisted Therapy/methods , Posture , Sitting Position , Postural Balance
3.
Chest ; 159(5): e299-e302, 2021 05.
Article in English | MEDLINE | ID: mdl-33965152

ABSTRACT

High spinal cord injured patients (SCI) are susceptible to respiratory muscle impairments. Transcranial direct current stimulation (tDCS) and peripheral electrical stimulation (PES) may influence the diaphragm's central control, but until now they are not described as a therapeutic resource for difficult weaning. We present two case reports of SCI patients (P1 and P2) with long-term tracheostomy (>40 days) and hospital stay (>50 days). In association with respiratory exercise, P1 received a combined application of anodal tDCS over the supplementary motor area plus sensory PES in the thoracic-abdominal muscles, and P2 received isolated excitatory PES in the abdominal muscles, applied daily except on weekends. Maximum inspiratory/expiratory pressure, peak cough flow, diaphragm excursion, and thickening fraction were measured in the first and last days of the protocol. Both patients had improvements, with clinical impact such as cough effectiveness, decannulated after 15 applications of stimulation. Augmentation of neural respiratory drive and corticospinal excitability is suggested.


Subject(s)
Electric Stimulation Therapy/methods , Spinal Cord Injuries/physiopathology , Spinal Cord Injuries/therapy , Tracheostomy , Transcranial Direct Current Stimulation , Adult , Breathing Exercises , Cervical Vertebrae/injuries , Cough , Humans , Length of Stay/statistics & numerical data , Male
4.
Rev. Pesqui. Fisioter ; 11(2): 427-434, Maio 2021. ilus, tab
Article in English, Portuguese | LILACS | ID: biblio-1254009

ABSTRACT

INTRODUÇÃO: As ataxias cerebelares são um extenso grupo de doenças que causam diversos distúrbios na marcha e no equilíbrio, e que comprometem seriamente a qualidade de vida, sem opções de tratamento eficazes. A cinesioterapia é a base de programas multifacetados que incorporam mais de um enfoque, como o treinamento de coordenação e equilíbrio. Recentemente, a estimulação transcraniana por corrente contínua (tDCS) sobre o cerebelo surgiu como uma intervenção para melhorar os distúrbios do equilíbrio. OBJETIVO: Descrever a aplicação simultânea de tDCS anódica cerebelar e cinesioterapia, em sessões múltiplas diárias para reabilitação da ataxia cerebelar. MATERIAIS E MÉTODOS: Este relato de caso incluiu um paciente do sexo masculino, de 34 anos, com história de ataxia espinocerebelar há 10 anos. Seus principais objetivos eram melhorar a marcha e o equilíbrio. Ele apresentava ataxia axial e apendicular, dificuldades na marcha e no equilíbrio. O protocolo de estimulação do cerebelo consistiu na aplicação de tDCS por 20 minutos, 2mA, diariamente, durante duas semanas, com ânodo posicionado sobre o ínion e cátodo sobre o músculo deltóide direito. A cinesioterapia simultânea incluiu exercícios funcionais progressivos com objetivo principal de treinamento de equilíbrio. RESULTADOS: A melhora clínica foi particularmente evidenciada por uma redução de 4 pontos na Escala para Avaliação e Graduação da Ataxia após 10 sessões, enquanto a literatura recomenda a eficácia de uma nova terapia que retardaria a progressão da ataxia em 1 ponto por ano. CONCLUSÃO: Nossos resultados sugerem que a associação entre tDCS e cinesioterapia foi eficaz neste paciente; as sessões de tDCS foram seguras e bem toleradas e podem ter desempenhado um papel na melhora nos testes funcionais. Novos estudos controlados envolvendo um número maior de pacientes são necessários para analisar os benefícios destas técnicas combinadas para maximizar a reabilitação motora nesta população.


INTRODUCTION: Cerebellar ataxias are an extensive group of diseases, which cause many disorders in gait and balance that seriously impair quality of life, and without effective treatment options. Kinesiotherapy is the basis of multifaceted programs that incorporate more than one focus, such as coordination and balance training. Recently, transcranial direct current stimulation (tDCS) over the cerebellum has emerged as an intervention to improve balance disorders. OBJECTIVE: To describe a daily multiple session's simultaneous application of anodal cerebellar tDCS to kinesiotherapy for rehabilitation in cerebellar ataxia. MATERIALS AND METHODS: This case report included a 34-year-old male patient with a 10-year history of spinocerebellar ataxia. His main goals were to improve his walking ability and balance. He presented with axial and appendicular ataxia, impaired gait, and balance. The protocol used to stimulate the cerebellum consisted of twenty-minute tDCS, 2mA, daily applied, over two weeks, with anode positioned over the inion and cathode over the right deltoid muscle. Simultaneous kinesiotherapy included progressive functional exercises with the main objective of balance training. RESULTS: Clinical improvement was particularly evidenced by a 4-point reduction in the Scale for the Assessment and Rating of Ataxia after ten sessions, while literature recommends efficacy of a new therapy that would retard ataxia progression by 1 point per year. CONCLUSION: Our results suggest that the association between tDCS and kinesiotherapy was effective in this patient; tDCS sessions were safe and well-tolerated and may have played a role in improving functional tests. Further controlled studies involving a larger number of patients are needed to analyze the benefits of these combined techniques to maximize motor rehabilitation in this population.


Subject(s)
Cerebellar Ataxia , Rehabilitation , Transcranial Direct Current Stimulation
5.
Photobiomodul Photomed Laser Surg ; 39(1): 30-37, 2021 Jan.
Article in English | MEDLINE | ID: mdl-33332202

ABSTRACT

Objective: To evaluate the effect of photobiomodulation (PBM) on cell viability, synthesis of nitric oxide (NO), and interleukin (IL)-6 inflammatory cytokine production in myoblasts cultured in the presence of lipopolysaccharides (LPSs). Methods: C2C12 myoblasts were treated with LPS and PBM using different parameters (wavelength: 780 nm; beam spot: 0.04 cm2; power output: 10 or 40 mW; energy density: 5 or 20 J/cm2; and 20-sec exposure time). Nonirradiated cells were used to the control group. Results: An increase in cell viability was found in both LPS groups in comparison with the control. PBM with the higher power output (40 mW) induced a reduction in cell viability. PBM also modulated the synthesis of NO in the myoblasts, but did not alter the expression of IL-6. Conclusions: Based on these findings, PBM is capable of modulating the cell viability and the production of NO in LPS-treated myoblasts and it is, therefore, a possible tool for the treatment of muscle injury caused by infection.


Subject(s)
Lipopolysaccharides , Low-Level Light Therapy , Myoblasts , Cell Survival , Gene Expression , Lipopolysaccharides/pharmacology
6.
Front Neurol ; 11: 573718, 2020.
Article in English | MEDLINE | ID: mdl-33324324

ABSTRACT

Background: Novel coronavirus disease (COVID-19) morbidity is not restricted to the respiratory system, but also affects the nervous system. Non-invasive neuromodulation may be useful in the treatment of the disorders associated with COVID-19. Objective: To describe the rationale and empirical basis of the use of non-invasive neuromodulation in the management of patients with COVID-10 and related disorders. Methods: We summarize COVID-19 pathophysiology with emphasis of direct neuroinvasiveness, neuroimmune response and inflammation, autonomic balance and neurological, musculoskeletal and neuropsychiatric sequela. This supports the development of a framework for advancing applications of non-invasive neuromodulation in the management COVID-19 and related disorders. Results: Non-invasive neuromodulation may manage disorders associated with COVID-19 through four pathways: (1) Direct infection mitigation through the stimulation of regions involved in the regulation of systemic anti-inflammatory responses and/or autonomic responses and prevention of neuroinflammation and recovery of respiration; (2) Amelioration of COVID-19 symptoms of musculoskeletal pain and systemic fatigue; (3) Augmenting cognitive and physical rehabilitation following critical illness; and (4) Treating outbreak-related mental distress including neurological and psychiatric disorders exacerbated by surrounding psychosocial stressors related to COVID-19. The selection of the appropriate techniques will depend on the identified target treatment pathway. Conclusion: COVID-19 infection results in a myriad of acute and chronic symptoms, both directly associated with respiratory distress (e.g., rehabilitation) or of yet-to-be-determined etiology (e.g., fatigue). Non-invasive neuromodulation is a toolbox of techniques that based on targeted pathways and empirical evidence (largely in non-COVID-19 patients) can be investigated in the management of patients with COVID-19.

7.
J Clin Neurosci ; 76: 208-210, 2020 Jun.
Article in English | MEDLINE | ID: mdl-32284289

ABSTRACT

Dystonia is a disabling movement disorder characterized by co-contraction of antagonist and agonist muscles, leading to abnormal sustained postures and impaired motor control. Cervical Dystonia (CD) and Hand Focal Dystonia (HFD) have been the most common forms of focal dystonia (FD). Do Non-Invasive Brain Neuromodulation (NIBS) such as Transcranial Direct Current Stimulation (tDCS) and repetitive Transcranial Magnetic Stimulation (rTMS) modulate the excitability of the connections between the motor cortical areas and may represent a therapeutic alternative for focal dystonia? Herein, we reported three cases of focal dystonia, two of them with cervical dystonia (CD) and one with hand focal dystonia (HFD), treated with NIBS combined to kinesiotherapy. The patients were daily submitted to 15 sessions of NIBS combined simultaneously with kinesiotherapy. CD patients were treated with tDCS (2 mA, 20 min, over the primary motor cortex), and HFD patient with rTMS (1 Hz, 1200 pulses, 80% of resting motor threshold, over the premotor cortex). For the CD patient's assessment, the Modified Toronto Scale for Cervical Dystonia Assessment (MTS), quiet balance test, and visual postural assessment were applied to observe the therapeutic effects. Quality handwriting analysis, tremor acceleration amplitudes, and the Wrinter's Cramp Rating Scale (WCRS) were used to assess the NIBS effect on HFD symptoms. Patients were evaluated before (pretest), immediately after (posttest), and three months after treatment (retention). NIBS associated with kinesiotherapy produced a long-term improvement of dystonia symptoms in all three patients. rTMS and tDCS associated with kinesiotherapy showed to be useful and safe to relief the dystonia symptoms in individuals with different types of focal dystonia with distinct functional disorders. SIGNIFICANCE: The combined use of these intervention strategies seems to optimize and anticipate satisfactory clinical results in these neurological conditions, characterized by its difficult clinical management.


Subject(s)
Dystonic Disorders/therapy , Transcranial Direct Current Stimulation , Transcranial Magnetic Stimulation , Aged , Female , Humans , Male , Middle Aged , Motor Cortex/physiopathology , Stereotaxic Techniques , Torticollis
9.
Res Dev Disabil ; 84: 122-130, 2019 Jan.
Article in English | MEDLINE | ID: mdl-30087016

ABSTRACT

AIM: The Animal Fun program, a universal early intervention program that aims to promote the motor skills and social-emotional development of young children, has shown to improve overall motor proficiency and social and behavioural outcomes. The aim of the current study was to evaluate the program's impact on children's aiming and catching, and balance skills. METHODS: A cluster randomised control trial was employed, with six intervention and six control (following normal curriculum) schools. A total sample of 511 children (257 boys and 254 girls), aged 4-6 years presented at pre-test. Children were tested across three time points, pre-test, post intervention (six months later) and follow-up (18 months after pre-test), using the Movement Assessment Battery for Children-2 Aiming and Catching, and Balance tasks. The study also tested for potential moderators including pre-test motor proficiency, age, gender, and cognitive performance. RESULTS: Participation in Animal Fun improved children's one leg balance at post-test and follow-up compared to control children, regardless of pre-test motor proficiency, age, gender, or pre-test cognitive performance. Participation in Animal Fun also improved throwing skills for those children with poorer motor proficiency compared to the controls with poorer motor performance. Interestingly, it was found that the control group's catching skills improved more than the intervention group at follow up. CONCLUSIONS: The study provides some promising results regarding the efficacy of the Animal Fun program in improving one-leg balance for all children, and throwing skills for those children with poorer motor proficiency, while also suggesting potential confounding factors, such as maturational issues and other individual factors (e.g., a child's participation in extracurricular activity).


Subject(s)
Early Intervention, Educational/methods , Motor Skills , Postural Balance , Child , Child, Preschool , Female , Humans , Imitative Behavior , Male , Schools
10.
J Bras Pneumol ; 44(3): 184-189, 2018.
Article in English, Portuguese | MEDLINE | ID: mdl-30043883

ABSTRACT

OBJECTIVE: To determine whether 24-h availability of physiotherapy services decreases ICU costs in comparison with the standard 12 h/day availability among patients admitted to the ICU for the first time. METHODS: This was an observational prevalence study involving 815 patients ≥ 18 years of age who had been on invasive mechanical ventilation (IMV) for ≥ 24 h and were discharged from an ICU to a ward at a tertiary teaching hospital in Brazil. The patients were divided into two groups according to h/day availability of physiotherapy services in the ICU: 24 h (PT-24; n = 332); and 12 h (PT-12; n = 483). The data collected included the reasons for hospital and ICU admissions; Acute Physiology and Chronic Health Evaluation II (APACHE II) score; IMV duration, ICU length of stay (ICU-LOS); and Omega score. RESULTS: The severity of illness was similar in both groups. Round-the-clock availability of physiotherapy services was associated with shorter IMV durations and ICU-LOS, as well as with lower total, medical, and staff costs, in comparison with the standard 12 h/day availability. CONCLUSIONS: In the population studied, total costs and staff costs were lower in the PT-24 group than in the PT-12 group. The h/day availability of physiotherapy services was found to be a significant predictor of ICU costs.


Subject(s)
Exercise Therapy/economics , Health Services Accessibility/economics , Intensive Care Units/economics , APACHE , Adult , Aged , Brazil , Exercise Therapy/statistics & numerical data , Female , Health Care Costs , Health Services Accessibility/statistics & numerical data , Humans , Intensive Care Units/statistics & numerical data , Length of Stay/economics , Length of Stay/statistics & numerical data , Linear Models , Male , Middle Aged , Respiration, Artificial/economics , Respiration, Artificial/statistics & numerical data , Severity of Illness Index , Statistics, Nonparametric , Time Factors
11.
Rev. Pesqui. Fisioter ; 8(2): 230-238, maio, 2018. tab
Article in English, Portuguese | LILACS | ID: biblio-915681

ABSTRACT

INTRODUÇÃO: Todos os anos, milhões de dólares são gastos para equipar e manter os centros de esterilização hospitalar no mundo. Materiais de terapia respiratória são essenciais para o suporte de vida e têm um grande impacto nas complicações clínicas. Fornecer materiais de terapia respiratória com higiene apropriada em um hospital é um desafio para os gestores devido ao impacto clínico e de custos. OBJETIVO: Comparar os custos de diferentes métodos de abastecimento de materiais de fisioterapia respiratória em um hospital geral, de porte extra, terciário e público. MÉTODOS: Consistiu em um estudo observacional, baseado em revisão documental e análise crítica de indicadores de gestão hospitalar, e analisou materiais utilizados em fisioterapia respiratória, classificados como semicríticos, incluindo ressuscitador manual, nebulizador, kit para pressão positiva contínua nas vias aéreas, circuito ventilatório para ventilação mecânica não invasiva e invasiva. RESULTADOS: Comparado ao processo de aquisição de materiais descartáveis, o processo de abastecimento no Centro de Material e Esterilização (CME) institucional gera uma economia anual com valores calculados em US$ 289.679,26; em comparação com o CME terceirizado, o processo de suprimento no CME institucional economiza um montante de US$ 257.041,11 por ano. CONCLUSÃO: Este foi o primeiro estudo brasileiro a realizar uma análise de custos nesse contexto. O processo de abastecimento com a higienização de materiais de fisioterapia respiratória na CME-INST mostrou-se mais vantajoso com menores custos quando comparado ao processo de abastecimento com higienização na CME-EXT ou custo de aquisição de MD. A economia anual estimada considerando o consumo médio mensal neste estudo ultrapassou US$ 250.000,00. A análise de custos detalhada fornece informações cruciais e pode permitir uma melhor gestão financeira. [AU]


INTRODUCTION: Every year millions of dollars are expended to equip and maintain the hospital sterilization centers in the world. Respiratory therapy materials are essential to life support, and have a major impact on clinical complications. To provide respiratory therapy materials with appropriate hygiene in a hospital is a challenge for manager due to clinical and costs impact. OBJECTIVE: To compare costs of different methods of providing respiratory therapy materials in a general, extra, tertiary and public hospital. METHODS: It consisted of an observational study, based on document review and critical analysis of hospital management indicators, and analyzed materials used in respiratory therapy, classified as semi-critical products, including manual resuscitator, nebulizer, kit for Continuous Positive Airway Pressure (CPAP), ventilatory circuit for non-invasive and invasive mechanical ventilation. RESULTS: Compared to the supply process of disposable materials acquisition, the supply process in the Institutional Central Sterilization Supply Department generates an annual savings with values calculated at US$ 289,679.26; while compared to the Outsourced Central Sterilization Supply Department the supply process in the Institutional Central Sterilization Supply Department saves an amount of US$ 257,041.11 annually. CONCLUSION: This was the first Brazilian study to conduct a cost analysis in this context. The supply process with the cleaning of respiratory physiotherapy materials in the Institutional Central Sterilization Supply Department was more advantageous with lower costs when compared to the Outsourced Central Sterilization Supply Department or cost of acquisition of disposable materials. The annual savings estimated considering the average monthly consumption in this study exceeded US $ 250,000.00. Detailed cost analysis provides crucial information and can enable better financial management. [AU]


Subject(s)
Hospital Administration , Hospital Costs , Sterilization
12.
J. bras. pneumol ; 44(3): 184-189, May-June 2018. tab, graf
Article in English | LILACS | ID: biblio-954558

ABSTRACT

ABSTRACT Objective: To determine whether 24-h availability of physiotherapy services decreases ICU costs in comparison with the standard 12 h/day availability among patients admitted to the ICU for the first time. Methods: This was an observational prevalence study involving 815 patients ≥ 18 years of age who had been on invasive mechanical ventilation (IMV) for ≥ 24 h and were discharged from an ICU to a ward at a tertiary teaching hospital in Brazil. The patients were divided into two groups according to h/day availability of physiotherapy services in the ICU: 24 h (PT-24; n = 332); and 12 h (PT-12; n = 483). The data collected included the reasons for hospital and ICU admissions; Acute Physiology and Chronic Health Evaluation II (APACHE II) score; IMV duration, ICU length of stay (ICU-LOS); and Omega score. Results: The severity of illness was similar in both groups. Round-the-clock availability of physiotherapy services was associated with shorter IMV durations and ICU-LOS, as well as with lower total, medical, and staff costs, in comparison with the standard 12 h/day availability. Conclusions: In the population studied, total costs and staff costs were lower in the PT-24 group than in the PT-12 group. The h/day availability of physiotherapy services was found to be a significant predictor of ICU costs.


RESUMO Objetivo: Determinar se a disponibilidade de serviços de fisioterapia 24 h/dia reduz os custos de UTI comparada à disponibilidade padrão de 12 h/dia entre pacientes admitidos pela primeira vez na UTI. Métodos: Estudo de prevalência observacional, envolvendo 815 pacientes ≥ 18 anos de idade que estavam em ventilação mecânica invasiva (VMI) por ≥ 24 h e que tiveram alta de uma UTI para uma enfermaria em um hospital universitário terciário no Brasil. Os pacientes foram divididos em dois grupos de acordo com a disponibilidade de serviços de fisioterapia na UTI em h/dia: 24 h (PT-24; n = 332); e 12 h (PT-12; n = 483). Os dados coletados incluíram os motivos das internações hospitalares e das admissões na UTI; a pontuação Acute Physiology and Chronic Health Evaluation II (APACHE II); a duração da VMI; o tempo de permanência na UTI (TP-UTI); e o escore Ômega. Resultados: A gravidade da doença foi similar em ambos os grupos. A disponibilidade ininterrupta de serviços de fisioterapia foi associada a tempos menores de VMI e TP-UTI, bem como a menores custos (totais, médicos e com pessoal), comparada à disponibilidade padrão de 12 h/dia. Conclusões: Na população estudada, os custos totais e os custos com pessoal foram menores no grupo PT-24 do que no grupo PT-12. A disponibilidade em h/dia dos serviços de fisioterapia mostrou ser um preditor significativo dos custos de UTI.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Exercise Therapy/economics , Health Services Accessibility/economics , Intensive Care Units/economics , Respiration, Artificial/economics , Respiration, Artificial/statistics & numerical data , Time Factors , Severity of Illness Index , Brazil , Linear Models , Health Care Costs , Statistics, Nonparametric , APACHE , Exercise Therapy/statistics & numerical data , Health Services Accessibility/statistics & numerical data , Intensive Care Units/statistics & numerical data , Length of Stay/economics , Length of Stay/statistics & numerical data
13.
J Atten Disord ; 22(8): 796-805, 2018 06.
Article in English | MEDLINE | ID: mdl-25862650

ABSTRACT

OBJECTIVE: This study investigated the relationship between motor performance; attentional, hyperactive, and impulsive symptoms; and social problems. Correlations between parents' versus teachers' ratings of social problems and ADHD symptomatology were also examined. METHOD: A total of 129 children aged 9 to 12 years were included. ADHD symptoms and social problems were identified based on Conners' Rating Scales-Revised: L, and the McCarron Assessment of Neuromuscular Development was used to assess motor skills. RESULTS: After controlling for ADHD symptomatology, motor skills remained a significant predictor of social problems in the teacher model but not in the parent model. After controlling for motor skills, inattentive (not hyperactive-impulsive) symptoms were a significant predictor of social problems in the parent model, whereas hyperactive-impulsive (not inattentive) symptoms were a significant predictor of social problems in the teacher model. CONCLUSION: The findings suggested that intervention strategies should consider the interaction between symptoms and environmental contexts.


Subject(s)
Attention Deficit Disorder with Hyperactivity/psychology , Motor Skills/physiology , Social Skills , Attention/physiology , Child , Female , Humans , Impulsive Behavior/physiology , Male , Parents , Social Problems/psychology
14.
Lasers Med Sci ; 33(3): 513-521, 2018 Apr.
Article in English | MEDLINE | ID: mdl-29181641

ABSTRACT

The purpose of this study was to evaluate the effects of low-level laser therapy (LLLT) on morphological aspects, IL-6 and IL-1ß expressions, as well as the distribution and organization of collagen in the tibialis anterior (TA) muscle of elderly rats submitted to cryoinjury. Histological photomicrographs were taken of TA muscles stained with HE and picrosirius red. Immunohistochemistry was used for the evaluation of IL-6 and IL-1ß. Male Wistar rats, aged 20 months, were distributed into three groups: (1) control animals not injured or treated with LLLT (n = 5), (2) cryoinjury without LLLT treatment (n = 15), and (3) cryoinjury treated with infrared LLLT (n = 15). LLLT was applied to the TA 2 h after of the injury induction and consisted of daily applications until the sacrifice (1, 3, and 7 days). The following parameters were used: λ = 780 nm, power density 1 W/cm2, output power 40 mW, 10 s per point, 8 points, and 3.2 J of total energy. In the histomorphological analysis, the treated group exhibited a significant decrease in inflammatory infiltrate (p < 0.001) as well as an increase immature fibers and new blood vessels at 7 days compared to the untreated group (p < 0.05). Furthermore, treatment induced a better collagen distribution and organization at 7 days in comparison to the untreated group (p < 0.05). In conclusion, LLLT demonstrated a modulatory effect on the muscle repair process in elderly animals with regard to the collagen remodeling and morphological aspects of muscle tissue.


Subject(s)
Aging/physiology , Connective Tissue/radiation effects , Low-Level Light Therapy , Muscle, Skeletal/physiology , Muscle, Skeletal/radiation effects , Regeneration/radiation effects , Animals , Fibrillar Collagens/metabolism , Interleukin-1beta/metabolism , Interleukin-6/metabolism , Male , Muscle, Skeletal/metabolism , Rats, Wistar
16.
Percept Mot Skills ; 124(2): 425-440, 2017 Apr.
Article in English | MEDLINE | ID: mdl-28361657

ABSTRACT

Attention deficit hyperactivity disorder (ADHD) is the most common neurobehavioral disorder during childhood, affecting approximately 3-6% of school-aged children; its cardinal symptoms of high activity, impulsivity, and behavioral distractibility might be assumed to have close relationships to interferences with motor skills. A separate body of literature attests to ways that motor problems can severely impact children's daily lives, as motor problems may occur in 30-50% of children with ADHD. This article critically reviews research on motor impairment in children with ADHD, notable differences in motor performance of individuals with ADHD compared with age-matched controls, and possible neural underpinnings of this impairment. We discuss the highly prevalent link between ADHD and developmental coordination disorder (DCD) and the lack of a clear research consensus about motor difficulties in ADHD. Despite increasing evidence and diagnostic classifications that define DCD by motor impairment, the role of ADHD symptoms in DCD has not been delineated. Similarly, while ADHD may predispose children to motor problems, it is unclear whether any such motor difficulties observed in this population are inherent to ADHD or are mediated by comorbid DCD. Future research should address the exact nature and long-term consequences of motor impairment in children with ADHD and elucidate effective treatment strategies for these disorders together and apart.


Subject(s)
Attention Deficit Disorder with Hyperactivity/physiopathology , Child Development/physiology , Comorbidity , Motor Skills Disorders/physiopathology , Motor Skills/physiology , Attention Deficit Disorder with Hyperactivity/epidemiology , Child , Humans , Motor Skills Disorders/epidemiology
17.
Res Dev Disabil ; 55: 279-86, 2016 Aug.
Article in English | MEDLINE | ID: mdl-27214681

ABSTRACT

BACKGROUND: Research has suggested an important association between motor proficiency and overweight/obesity. Many children with motor difficulties experience ADHD symptoms which have also been linked with overweight/obesity. Previous research has not considered both ADHD and motor performance when investigating their relationship with overweight/obesity. AIMS: To investigate the relationships between motor performance, ADHD symptoms, and overweight/obesity in children. METHODS AND PROCEDURES: A cross-sectional study was conducted involving189 children aged six to 10 years. Symptoms of ADHD were identified using the SNAP-IV rating scale. Motor impairment (MI) was identified using the Movement Battery Assessment for Children-2. Body composition was estimated from the Body Mass Index (BMI) based on World Health Organization child growth standards. OUTCOMES AND RESULTS: Balance was the only motor skill associated with BMI even after controlling for gender and ADHD. Group comparisons revealed that the proportion of overweight ADHD children was significantly less than the proportion of overweight control children and overweight MI children; the proportion of underweight ADHD children was significantly greater than the proportion of underweight MI children. CONCLUSIONS AND IMPLICATIONS: The results highlight the importance of taking into consideration both ADHD symptoms and motor difficulties in the assessment and intervention of physical health outcomes in children with ADHD and/or movement problems.


Subject(s)
Attention Deficit Disorder with Hyperactivity/epidemiology , Motor Skills Disorders/epidemiology , Motor Skills , Obesity/epidemiology , Postural Balance , Thinness/epidemiology , Attention Deficit Disorder with Hyperactivity/psychology , Body Mass Index , Body Weight , Brazil/epidemiology , Child , Cross-Sectional Studies , Female , Humans , Male , Motor Skills Disorders/physiopathology , Overweight/epidemiology
18.
Braz J Psychiatry ; 37(3): 228-34, 2015.
Article in English | MEDLINE | ID: mdl-26376053

ABSTRACT

OBJECTIVE: To compare both global and specific domains of motor development of children with attention deficit hyperactivity disorder (ADHD) with that of typically developing children. METHODS: Two hundred children (50 children with clinical diagnoses of ADHD, according to the DSM-IV-TR and 150 typically developing controls), aged 5 to 10 years, participated in this cross-sectional study. The Motor Development Scale was used to assess fine and global motricity, balance, body schema, and spatial and temporal organization. RESULTS: Between-group testing revealed statistically significant differences between the ADHD and control groups for all domains. The results also revealed a deficit of nearly two years in the motor development of children with ADHD compared with the normative sample. CONCLUSION: The current study shows that ADHD is associated with a delay in motor development when compared to typically developing children. The results also suggested difficulties in certain motor areas for those with ADHD. These results may point to plausible mechanisms underlying the relationship between ADHD and motor difficulties.


Subject(s)
Attention Deficit Disorder with Hyperactivity/physiopathology , Child Development/physiology , Motor Skills/physiology , Age Factors , Body Image , Case-Control Studies , Child , Cross-Sectional Studies , Disability Evaluation , Female , Humans , Male , Postural Balance/physiology , Psychiatric Status Rating Scales , Spatial Behavior/physiology , Statistics, Nonparametric
19.
Braz. J. Psychiatry (São Paulo, 1999, Impr.) ; 37(3): 228-234, July-Sept. 2015. tab
Article in English | LILACS | ID: lil-759425

ABSTRACT

Objective:To compare both global and specific domains of motor development of children with attention deficit hyperactivity disorder (ADHD) with that of typically developing children.Methods:Two hundred children (50 children with clinical diagnoses of ADHD, according to the DSM-IV-TR and 150 typically developing controls), aged 5 to 10 years, participated in this cross-sectional study. The Motor Development Scale was used to assess fine and global motricity, balance, body schema, and spatial and temporal organization.Results:Between-group testing revealed statistically significant differences between the ADHD and control groups for all domains. The results also revealed a deficit of nearly two years in the motor development of children with ADHD compared with the normative sample.Conclusion:The current study shows that ADHD is associated with a delay in motor development when compared to typically developing children. The results also suggested difficulties in certain motor areas for those with ADHD. These results may point to plausible mechanisms underlying the relationship between ADHD and motor difficulties.


Subject(s)
Child , Female , Humans , Male , Attention Deficit Disorder with Hyperactivity/physiopathology , Child Development/physiology , Motor Skills/physiology , Age Factors , Body Image , Case-Control Studies , Cross-Sectional Studies , Disability Evaluation , Postural Balance/physiology , Psychiatric Status Rating Scales , Spatial Behavior/physiology , Statistics, Nonparametric
20.
Behav Brain Res ; 292: 484-92, 2015 Oct 01.
Article in English | MEDLINE | ID: mdl-26168770

ABSTRACT

Attention deficit hyperactivity disorder (ADHD) has been described as the most prevalent behavioral disorder in children. Developmental coordination disorder (DCD) is one of the most prevalent childhood movement disorders. The overlap between the two conditions is estimated to be around 50%, with both substantially interfering with functioning and development, and leading to poorer psychosocial outcomes. This review provides an overview of the relationship between ADHD and DCD, discussing the common presenting features, etiology, neural basis, as well as associated deficits in motor functioning, attention and executive functioning. It is currently unclear which specific motor and cognitive difficulties are intrinsic to each disorder as many studies of ADHD have not been screened for DCD and vice-versa. The evidence supporting common brain underpinnings is still very limited, but studies using well defined samples have pointed to non-shared underpinnings for ADHD and DCD. The current paper suggests that ADHD and DCD are separate disorders that may require different treatment approaches.


Subject(s)
Attention Deficit Disorder with Hyperactivity/etiology , Attention Deficit Disorder with Hyperactivity/physiopathology , Brain/physiopathology , Motor Skills Disorders/etiology , Motor Skills Disorders/physiopathology , Attention/physiology , Child , Executive Function/physiology , Female , Humans , Male
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