ABSTRACT
Presentamos el caso de un paciente varón de 37años con cuadro compatible con conjuntivitis adenovírica de 5días de evolución. Se pautaron corticoides tópicos, lubricantes y retirada de pseudomembranas. El análisis mediante PCR del exudado conjuntival resultó positivo para Monkeypox virus. Durante el seguimiento presentó úlceras corneales de evolución tórpida, por lo que precisó ingreso para instaurar tratamiento con tecovirimat. La afectación ocular por Monkeypox virus suele ser leve y autolimitada. Se han descrito casos con afectación visual severa cuando hay daño corneal, tal y como se ejemplifica en este caso. Tras el ingreso hospitalario para tratamiento sistémico, presentó una evolución favorable. (AU)
We present the case of a 37-year-old male patient with symptoms compatible with adenoviral conjunctivitis of 5days evolution. Topical corticosteroids, lubricants and removal of pseudomembranes were prescribed. PCR analysis of conjunctival exudate was positive for Monkeypox virus. During follow-up, the patient developed corneal ulcers with a torpid course, requiring admission for treatment with tecovirimat. Ocular involvement by Monkeypox virus is usually mild and self-limiting. Cases with severe visual involvement have been described when there is corneal damage, as exemplified in this case. After admission to hospital for systemic treatment, the patient progressed favourably. (AU)
Subject(s)
Humans , Male , Adult , Conjunctivitis/diagnosis , Corneal Ulcer , Glucocorticoids , Monkeypox virusABSTRACT
We present the case of a 37-year-old male patient with symptoms compatible with adenoviral conjunctivitis of 5 days' evolution. Topical corticosteroids, lubricants and removal of pseudomembranes were prescribed. PCR analysis of conjunctival exudate was positive for Monkeypox virus. During follow-up, the patient developed corneal ulcers with a torpid course, requiring admission for treatment with Tecovirimat. Ocular involvement by Monkeypox virus is usually mild and self-limiting. Cases with severe visual involvement have been described when there is corneal damage, as exemplified in this case. After admission to hospital for systemic treatment, the patient progressed favourably.
Subject(s)
Conjunctivitis , Corneal Ulcer , Mpox (monkeypox) , Male , Humans , Adult , Monkeypox virus , Conjunctivitis/diagnosis , GlucocorticoidsABSTRACT
PURPOSE: To evaluate the relation between dry eye severity and quality of life. METHODS: 40 participants (19 with dry eye and 21 normal controls) underwent slit-lamp examination and Schirmer test to evaluate dry eye severity. Quality of life was evaluated with OSDI (Ocular Surface Disease Index) and VFQ-25 (Visual Function Questionnaire-25). RESULTS: The OSDI total score was significantly greater in patients suffering dry eye. However, BUT (break-up time) and VFQ-25 total score were significantly lower than in control subjects. In dry eye patients several statistically significant correlations (p<0.05) were found: OSDI with VFQ-25 total score (r=-0.62), BUT with corneal staining (r=-0.50) and Schirmer (0.66), BUT with OSDI total score, OSDI-symptoms and OSDI-triggers (r=-0.56, -0.56, -0.60); corneal staining with OSDI total score and OSDI-symptoms (r=0.55, 0.54), BUT with VFQ-25 total score, VFQ-25 ocular pain, mental function and role function. (r=0.56, 0.51, 0.63, 0.56); corneal staining with VFQ-25 total score, VFQ-25 ocular pain and near vision (r=-0.57, -0.49, -0.62). CONCLUSION: Quality of life is decreased in patients with dry eye. OSDI and VFQ-25 questionnaires are valid instruments for measuring the impact of dry eye disease. BUT and corneal staining provide an indirect measurement of quality of life.
Subject(s)
Dry Eye Syndromes/psychology , Adult , Aged , Case-Control Studies , Dry Eye Syndromes/complications , Dry Eye Syndromes/diagnosis , Dry Eye Syndromes/epidemiology , Female , Humans , Male , Middle Aged , Quality of Life , Rose Bengal , Severity of Illness Index , Staining and Labeling , Surveys and Questionnaires , Tears/chemistry , Tears/metabolism , Vision Disorders/etiology , Vision Disorders/psychologyABSTRACT
Objetivos: Evaluar la relación entre la severidad deojo seco y la calidad de vida.Material y métodos: 19 pacientes diagnosticadosde ojo seco y 21 sin ojo seco fueron explorados conlámpara de hendidura y se les realizó el test deSchirmer, para evaluar el grado de severidad de ojoseco. La calidad de vida fue valorada con los cuestionariosOSDI (Ocular Surface Disease Index) andVFQ-25 (Visual Function Questionnaire-25).Resultados: La puntuación total del OSDI era significativamentemayor en los pacientes con ojoseco, mientras que el BUT y la puntuación total delVFQ-25 era significativamente menor que en lossanos. En los casos, se encontraron las siguientescorrelaciones estadísticamente significativas(p<0,05): Puntuación total del OSDI con la puntuacióntotal del VFQ-25 (r=-0,62), BUT con la tincióncorneal (r=-0,50) y con el Schirmer (r=0,66), BUTcon la puntuación total del OSDI, los síntomas y losdesencadenantes del OSDI (r=-0,56, -0,56, -0,60);tinción corneal con la puntuación total del OSDI ylos síntomas del OSDI (r=0,55, 0,54); BUT con lapuntuación total del VFQ-25, la ausencia de dolorocular, la función mental y la función laboral delVFQ-25 (r=0,56, 0,51, 0,63, 0,56); la tinción cornealcon la puntuación total del VFQ-25, la ausenciade dolor ocular y la visión cercana del VFQ-25 (r=-0,57, -0,49, -0,62).Conclusión: Los pacientes con ojo seco tienen unapeor de calidad de vida. Tanto el OSDI como elVFQ-25 son métodos adecuados de evaluación. ElBUT y la tinción corneal proporcionan una medidaindirecta de la calidad de vida (AU)
Purpose: To evaluate the relation between dry eyeseverity and quality of life.Methods: 40 participants (19 with dry eye and 21normal controls) underwent slit-lamp examinationand Schirmer test to evaluate dry eye severity. Qualityof life was evaluated with OSDI (Ocular SurfaceDisease Index) and VFQ-25 (Visual FunctionQuestionnaire-25).Results: The OSDI total score was significantlygreater in patients suffering dry eye. However, BUT(break-up time) and VFQ-25 total score were significantlylower than in control subjects.In dry eye patients several statistically significantcorrelations (p<0.05) were found:OSDI with VFQ-25 total score (r=-0.62), BUT withcorneal staining (r=-0.50) and Schirmer (0.66),BUT with OSDI total score, OSDI-symptoms andOSDI-triggers (r=-0.56, -0.56, -0.60); corneal stainingwith OSDI total score and OSDI-symptoms(r=0.55, 0.54), BUT with VFQ-25 total score,VFQ-25 ocular pain, mental function and role function.(r=0.56, 0.51, 0.63, 0.56); corneal stainingwith VFQ-25 total score, VFQ-25 ocular pain andnear vision (r=-0.57, -0.49, -0.62).Conclusion: Quality of life is decreased in patientswith dry eye. OSDI and VFQ-25 questionnaires arevalid instruments for measuring the impact of dryeye disease. BUT and corneal staining provide an tinción corneal.indirect measurement of quality of life (AU)
