ABSTRACT
Los medicamentos antiinflamatorios no esteroideos (AI-NEs) se encuentran entre los medicamentos más consu-midos mundialmente. Esto hace necesario realizar unasíntesis amplia de la evidencia disponible sobre la pres-cripción segura y adecuada de AINEs en pacientes conenfermedad cardiovascular, enfermedad renal crónica,hipertensión, insuficiencia cardíaca o cirrosis hepáticay en población general. Para ello se ha realizado unarevisión de revisiones sistemáticas. El uso de AINEs seasoció a una probabilidad significativamente mayor dehepatotoxicidad y daño renal y un mayor riesgo de exa-cerbación de la insuficiencia cardíaca. Teniendo en cuen-ta el aumento del riesgo cardiovascular, hepático y renal,la prescripción de AINEs debe realizarse con cautela,considerando la duración del tratamiento y la situacióndel paciente. Por ello, se debe informar a los pacientessobre sus posibles consecuencias para la salud así comogarantizar un seguimiento adecuado de los mismos.(AU)
Non-steroidal anti-inflammatory drugs (NSAIDs) areamong the most widely used drugs worldwide. Thismakes it necessary to carry out a comprehensivesynthesis of the available evidence on the safe andadequate prescription of NSAIDs in patients with car-diovascular disease, chronic kidney disease, hyper-tension, heart failure or liver cirrhosis and in generalpopulation. For this, a review of systematic reviewswas carried out. The use of NSAIDs is associated witha significantly higher probability of hepatotoxicity andkidney damage, as well as increased risk of exacerba-tion of heart failure. Taking into account the increasedcardiovascular, liver and kidney risk, the prescription ofNSAIDs should be carried out with caution, consideringthe treatment duration and the patients situation. Forthis reason, patients should be informed about theirpossible health consequences as well as ensuring ade-quate monitoring of them.(AU)
Subject(s)
Humans , Anti-Inflammatory Agents, Non-Steroidal , Drug Prescriptions , Inappropriate Prescribing , Cardiovascular Diseases , Renal Insufficiency, Chronic , Hypertension , Public Health , Health SystemsABSTRACT
AIMS: To identify health Websites in Spanish on adolescence and youth and to assess the adequacy of their codes of conduct. METHODS: Cross sectional study of the adequacy of codes of conduct, identified in the same way as young people tend to look on the Internet (search engines). Websites have been independently assessed using a questionnaire by 3 evaluators. Dimensions: 1) accountability, 2) transparency and honesty, 3) author, 4) editorial policy, 5) protection of personal data, 6) updating of information and accessibility. A descriptive analysis was performed and the kappa coefficient was estimated to assess the correlation between evaluators. RESULTS: A total of 66.7% of Websites had Spanish suppliers. There were 13 Websites (30.9%) with high compliance: Information for adolescents from the Spanish Association of Pediatrics (Spain), Health Center Manuel Merino Alcala de Henares (Spain), State Family Planning Federation (Spain), Webteens of the Generalitat Catalonia (Spain), Young Information Institutes Health (USA), Information on Female teenagers (USA), Information doctors and educators on type I diabetes (Spain), occupational asthma Portal (10 countries), teenage Information Puleva Group (Spain), Information bulimia and anorexia of the Community of Madrid (Spain), Health of adolescence PulsoMed, SA (Spain), American Association of Family Physicians (USA) and Information for young people from the Mapfre Health Fund (Spain). The worst dimension was updating of information (57.1% with low fullfilment) and protection of personal data, 21% with low fullfilment. The level of concordance between observers was considerable. CONCLUSIONS: A list was obtained of websites with health information on adolescence and youth, with variability in adequacy in codes of conduct.
