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Biochem Mol Biol Int ; 33(5): 1001-10, 1994 Aug.
Article in English | MEDLINE | ID: mdl-7987247

ABSTRACT

Antarctic Krill is considered as a valuable protein resource for animal and human nutrition. Due to the high content of long chain polyunsaturated fatty acids of the n-3 family, Krill consumption could be also interesting in cardiovascular diseases. In the search for the demonstration of the absence of toxicity of Krill, we studied the effect of Krill oil, as compared to fish and corn oil, on the rat intestinal fucosylation process at weaning, a very sensitive model of the influence of nutritional factors. Krill oil containing diets were very well tolerated as compared to other currently used oils and induced only slight modification in fucose and mannose proportions in intestinal glycoprotein sugars. These modifications were not reflected in the enzymatic activities involved in the fucosylation pathway. These results confirm the harmlessness of Krill derived products and their possible use in human nutrition.


Subject(s)
Corn Oil/pharmacology , Crustacea/chemistry , Dietary Fats, Unsaturated/pharmacology , Fish Oils/pharmacology , Intestinal Mucosa/metabolism , Animals , Body Weight , Corn Oil/chemistry , Diet , Fatty Acids/analysis , Glycoproteins/chemistry , Glycosylation/drug effects , Glycosyltransferases/metabolism , Hexoses/analysis , Intestines/enzymology , Intestines/growth & development , Male , Organ Size , Rats , Rats, Sprague-Dawley
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