ABSTRACT
No disponible
Subject(s)
Humans , Male , Female , Antiviral Agents/therapeutic use , Surveys and Questionnaires/standards , Surveys and Questionnaires , Patient Compliance , Bacterial Adhesion , Immune Adherence Reaction/trendsSubject(s)
HIV Infections/complications , Sleep Wake Disorders/etiology , Adult , Female , HIV Infections/physiopathology , Humans , Male , Middle Aged , Young AdultABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Pneumonia/complications , Pneumonia/diagnosis , Bacteremia/complications , Discitis/complications , Discitis/diagnosis , Dyspnea/complications , Fluid Therapy/methods , Prednisone/therapeutic use , Cloxacillin/therapeutic use , Oxygen/therapeutic use , Staphylococcus aureus/isolation & purification , Staphylococcus aureus/pathogenicity , Respiratory Sounds/diagnosis , Respiratory Sounds/physiopathology , Radiography, Thoracic/methods , Adrenal Cortex Hormones/therapeutic use , Ofloxacin/therapeutic use , Norepinephrine/therapeutic use , Bronchial Spasm/complicationsABSTRACT
No disponible
Subject(s)
Internal Medicine/education , Education, Medical/trends , Medicine/trendsABSTRACT
Creutzfeldt-Jakob disease is a prion spongiform encephalopathy that causes a rapidly progressive dementia whose neuropathological features are neuronal loss, proliferation of glial cells, and the presence of small vacuoles, which produces a spongiform appearance. Two cases detected in the year 2005 in the <
Subject(s)
Creutzfeldt-Jakob Syndrome/diagnosis , Aged , Female , Humans , Male , Middle Aged , SpainABSTRACT
No disponible
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Sleep/physiology , Acquired Immunodeficiency Syndrome/complications , Acquired Immunodeficiency Syndrome/diagnosis , Quality of Life , Apnea/complications , Sleep Wake Disorders/complications , Sleep Wake Disorders/diagnosis , Heart Failure/complications , Cardiovascular Diseases/complications , Hypertension/complicationsABSTRACT
La enfermedad de Creutzfeldt-Jakob (ECJ) es una encefalopatía espongiforme producida por priones que provoca una demencia progresiva cuyas características neuropatológicas son la pérdida neuronal, la proliferación de células gliales y las vacuolas, lo que origina el aspecto de esponja. Se presentan dos casos detectados en el año 2005 en el Hospital Nuestra Señora del Prado. El primero es el de un hombre que comenzó con intensa astenia y cuadro constitucional, desarrollando una demencia en 4 meses; y el segundo caso es el de una mujer que comenzó con diplopía, cefalea y alteraciones de la marcha, desarrollando un deterioro neurológico con demencia en tres meses. En ambos casos la proteína 14.3.3 del líquido cefalorraquídeo fue positiva y el electroencefalograma mostró un patrón característico. Los estudios genéticos fueron negativos, y ambos presentaban polimorfismo del codón 129, siendo homocigotos para la metionina. Nos ha sorprendido la aparición de dos casos en menos de un año en Talavera de la Reina y nos ha hecho aumentar la vigilancia
Creutzfeldt-Jakob disease is a prion spongiform encephalopathy that causes a rapidly progressive dementia whose neuropathological features are neuronal loss, proliferation of glial cells, and the presence of small vacuoles, which produces a spongiform appearance. Two cases detected in the year 2005 in the «Nuestra Señora del Prado» Hospital are presented. The first one is the case of a man who presented with intense malaise and weight loss, developing dementia in 4 months. The second one was a woman who presented with diplopia, headache and gait disturbances who developed severe neurological impairment with dementia in three months. In both cases the 14.3.3 protein in the cerebrospinal fluid was positive and the EEG showed a characteristic pattern. The genetic studies were negative and both were homozygous for methionine at codon 129. Given that the incidence of this disease in Castilla la Mancha is 0.6 cases/100000 inhabitants/year, the detection of 2 cases in less than a year in Talavera de la Reina (whose population is 150,000) surprised us, leading us to intensify surveillance
Subject(s)
Humans , Male , Female , Middle Aged , Aged , Creutzfeldt-Jakob Syndrome/diagnosis , Creutzfeldt-Jakob Syndrome/physiopathology , Prion Diseases/physiopathology , Methionine/genetics , Myoclonus/etiologyABSTRACT
No disponible
Subject(s)
Humans , Biomarkers, Tumor , Neoplasms/diagnosis , Sensitivity and SpecificityABSTRACT
Four cases of malaria in patients who had travelled to Equatorial Guinea the previous weeks and had not received prophylaxis are presented. There were three men and one woman, two natives of Equatorial Guinea who had been living in Spain for a long time and the other two Spanish. Following a 15-30 day trip in Equatorial Guinea they all presented with fever, shivering, headache and diarrhea( two cases) five to ten days after their return. Only one patient presented splenomegaly. The thick blood smear showed plasmodia in all patients and P. falciparum was identified in only two patients. All of them were treated with doxycycline and quinine sulfate with a favourable outcome. Only one of the patients needed hospitalization. Following some aspects of the epidemiology, symptoms, diagnosis and treatment of this emerging disease are presented.
Subject(s)
Malaria , Travel , Adult , Female , Humans , Malaria/diagnosis , Malaria/drug therapy , Malaria/epidemiology , Male , Middle AgedABSTRACT
A case of a 30-year-old man is presented. He had a past medical history of asthma and presented with cough, shortness of breath, fever and chest pain. The chest X-ray showed cardiomegaly and a interstitial pattern. The echocardiogram revealed a severe pericardial effusion that required performing a pericardiocentesis. A CT scan showed mediastinal adenopathies and reticulonodular interstitial pattern. A bronchoscopy could not be completed because of non-tolerance. Finally a lung biopsy allowed us to reach a final diagnosis of lung adenocarcinoma. Following, some aspects of lung cancer in young people are commented, especially its incidence, histology, symptoms and a prognosis. A few aspects of the interstitial lung disease are also addressed and the differential diagnosis with lymphangitic carcinomatosis.
Subject(s)
Adenocarcinoma, Papillary/diagnosis , Lung Diseases, Interstitial/diagnosis , Lung Neoplasms/diagnosis , Adenocarcinoma, Papillary/complications , Adenocarcinoma, Papillary/diagnostic imaging , Adenocarcinoma, Papillary/drug therapy , Adenocarcinoma, Papillary/secondary , Adult , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Cardiac Tamponade/etiology , Cardiac Tamponade/surgery , Cardiomegaly/etiology , Cisplatin/administration & dosage , Deoxycytidine/administration & dosage , Deoxycytidine/analogs & derivatives , Dyspnea/etiology , Fibrosis , Humans , Lung Neoplasms/complications , Lung Neoplasms/diagnostic imaging , Lung Neoplasms/drug therapy , Lung Neoplasms/pathology , Lymphatic Metastasis , Male , Radiography , GemcitabineSubject(s)
Hospital Units/standards , Patient Satisfaction , Surveys and Questionnaires , Humans , SpainABSTRACT
No disponible
