ABSTRACT
Introducción. El pancreatoblastoma (PB) es un tumor pancreático, embrionario, maligno. Debido a su rareza, no existe un criterio unánime con respecto al tratamiento. Presentamos un caso de diagnóstico prenatal. Caso clínico. Recién nacido con diagnóstico prenatal de tumoración epigástrica. Al ingreso, se palpa una masa en epigastrio que en ecografía presenta un aspecto quístico. Los marcadores tumorales BHCG, (ÏEA, CA, alfa-fetoproteína son: negativos, así como: TC, RM y mapa óseo. Mediante laparotomía, se extirpa una masa quística situada en la cola del páncreas. Estudios histopatológico: PB. Comentarios. Debido a su rareza, la mayoría de los Oncólogos no tienen experiencia en su tratamiento. No realizamos ninguna quimioterapia, debido a su resección completa y a que no hay un protocolo de quimioterapia establecido. Los pacientes con antecedente de PB presentan una mayor tendencia a desarrollar nuevos tumores. En nuestro paciente, después de 5 años, no hemos comprobado la aparición de ningún nuevo tumor (AU)
Introduction. Pancreatoblastoma (PB) is a pancreatic embryonic malignant tumor. Due to its rarity, there is no unanimous opinion regarding treatment. We present a case of prenatal diagnosis. Clinical case. A newborn with prenatal diagnosis of epigastric tumor. At admission, a palpable epigastric mass shows cystic appearance on echography: tumor markers BHCG, CEA, CA, and alpha-fetoprotein are negative, as well as CT, MR, bone map, 8C PET-CT. Through laparotomy, a cystic mass is excised from the tail of the pancreas. Histopathological studies: PB. Comments. Because of its clinical rarity, the majority of oncologists do not have experience of its treatment. We do not perform any chemotherapy, due to complete resection and also because of lack of established treatment protocol. Patients with a history of PB presents a greater tendency to develop new tumors. Alter 5 years we have not verified the emergence of any new tumor in our patient (AU)
Subject(s)
Humans , Male , Infant, Newborn , Pancreatic Neoplasms/complications , Pancreatic Neoplasms/surgery , Pancreatic Neoplasms , Prenatal Diagnosis/instrumentation , Prenatal Diagnosis/methods , Prenatal Diagnosis , alpha-Fetoproteins/analysis , Prenatal Diagnosis/standards , Prenatal Diagnosis/trends , Colon, Transverse/pathology , Colon, Transverse , Abdomen/pathology , AbdomenABSTRACT
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Subject(s)
Humans , Female , Child , Peliosis Hepatis , Magnetic Resonance Imaging/methods , Peliosis Hepatis/complications , Peliosis Hepatis/surgery , Abdomen/pathology , Abdomen , Shock, Hemorrhagic/complications , Shock, Hemorrhagic , Diagnosis, DifferentialABSTRACT
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Subject(s)
Humans , Female , Child , Osteomyelitis/complications , Osteomyelitis/diagnosis , Neoplasm Recurrence, Local/complications , Neoplasm Recurrence, Local/diagnosis , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Osteomyelitis/surgery , Osteomyelitis , Magnetic Resonance Imaging/methods , Clavicle/pathology , Clavicle , Physical Therapy Modalities/trendsABSTRACT
The hydatidosis is a frequent zoonosis in Spain, but isolated location in pancreas and their onset as acute abdomen is excepcional. We present a boy 14 years old, with abdominal pain and low-grade fever since 1 month. Hemogram shows eosinophilia, and echography an anechoic mass in tail of pancreas beside of free peritoneal liquid. At surgery procedure: a broken hydatid cyst is verified, surrounded of tissues inflammatory reaction that evolved to pancreatic fistula. The differents forms from clinical presentation of the pancreatic hydatid cyst, as well as the complications related to their location are analyzed.
Subject(s)
Abdomen, Acute/parasitology , Echinococcosis/complications , Abdomen, Acute/diagnostic imaging , Adolescent , Albendazole/therapeutic use , Anthelmintics/therapeutic use , Combined Modality Therapy , Echinococcosis/diagnostic imaging , Echinococcosis/therapy , Humans , Male , Pancreatic Diseases/complications , Pancreatic Diseases/diagnostic imaging , Pancreatic Diseases/therapy , Tomography, X-Ray Computed , UltrasonographyABSTRACT
La hidatidosis es una zoonosis frecuente en España; sin embargo, la localización única en páncreas y su aparición como abdomen agudo es excepcional. Presentamos un varón de 14 años de edad, con historia de dolor abdominal y febrícula de 1 mes de evolución. En el hemograma se observa una eosinofilia y en la ecografía se comprueba la existencia de una masa anecoica en cola de páncreas, además de líquido libre. Durante la intervención, se comprueba la existencia de un quiste hidatídico (QH) roto, con reacción inflamatoria de los tejidos de alrededor, que posteriormente hizo un pseudoquiste pancreático como consecuencia de una fístula pancreática. Se analizan las diferentes formas de presentación clínica de los QH pancreáticos, así como las complicaciones originadas por su localización (AU)
The hydatidosis is a frequent zoonosis in Spain, but isolated location in pancreas and their onset as acute abdomen is excepcional. We present a boy 14 years old, with abdominal pain and low-grade fever since 1 month. Hemogram shows eosinophilia, and echography an anechoic mass in tail of pancreas beside of free peritoneal liquid. At surgery procedure: a broken hydatid cyst is verified, surrounded of tissues inflammatory reaction that evolved to pancreatic fistula. The differents forms from clinical presentation of the pancreatic hydatid cyst, as well as the complications related to their location are analysed (AU)
Subject(s)
Male , Adult , Humans , Abdomen, Acute/parasitology , Echinococcosis/complications , Pancreatic Diseases/complications , Abdomen, Acute , Abdomen, Acute , Albendazole/therapeutic use , Anthelmintics/therapeutic use , Combined Modality Therapy , Echinococcosis/therapy , Echinococcosis , Pancreatic Diseases/therapy , Pancreatic Diseases , Tomography, X-Ray ComputedABSTRACT
INTRODUCTION: Miller-Dieker syndrome is characterized for type 1 lissencephaly associated with facial dysmorphism. In 90-95% of the cases, deletion of the distal fragment of chromosome 17 is seen. Nevertheless, this is difficult to confirm in about 50% of the cases, if we don't resort to special technics of molecular genetics. CLINICAL CASE: We show a 3 years old patient diagnosed of lissencephaly and with peculiar facial features in whom the cytogenetic study was normal, but by in situ hybridization deletion of 17p13.3 fragment was showed. CONCLUSION: We want to emphasize the ultrasonography findings and we want to suggest this easy imaging method and useful technic in the study of neuronal migrational disorders.
Subject(s)
Brain Diseases/diagnosis , Brain/abnormalities , Echoencephalography/methods , Anticonvulsants/therapeutic use , Brain Diseases/genetics , Child, Preschool , Chromosome Deletion , Chromosomes, Human, Pair 17/genetics , Epilepsy/diagnosis , Epilepsy/drug therapy , Female , Humans , Magnetic Resonance Imaging , SyndromeABSTRACT
Introducción. El síndrome de Miller-Dieker se caracteriza por la asociación de lisencefalia tipo I con dismorfia facial. En el 90-95 por ciento de los casos se observa deleción del fragmento distal del cromosoma 17; sin embargo, este hecho es difícil de comprobar en aproximadamente la mitad de los casos si no se recurre a técnicas especiales de genética molecular. Caso clínico. Presentamos una nueva observación en una paciente de 3 años diagnosticada de lisencefalia y con rasgos faciales peculiares, cuyo estudio citogenético resultó normal, pero por hibridación in situ pudo evidenciarse la deleción de la banda 17p13.3. Conclusión. Queremos destacar los hallazgos de ecografía transfontanelar y sugerir este método de imagen como técnica sencilla y útil en el estudio de los trastornos de la migración neuronal (AU)
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