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1.
Br J Dev Psychol ; 34(2): 169-80, 2016 06.
Article in English | MEDLINE | ID: mdl-26568283

ABSTRACT

This study examines children's comprehension of non-essential counting features (conventional rules). The objective of the study was to determine whether the presence or absence of cardinal values in pseudoerrors and the type of conventional rule violated affects children's performance. A detection task with pseudoerrors was presented through a computer game to 146 primary school children in grades 2 through 4. The same pseudoerrors were presented both with and without cardinal values; the pseudoerrors violated conventional rules of spatial adjacency, temporal adjacency, spatial-temporal adjacency, and left-to-right direction. Half of the participants within each age group were randomly assigned to an experimental condition that included pseudoerrors with a cardinal value, and the other half were assigned to a condition that included pseudoerrors without a cardinal value. The results show that when presented with a cardinal value, children more easily recognize the optional nature of non-essential counting features. Likewise, the type of conventional rule transgressed significantly affected the children's acceptance of pseudoerrors as valid counts. Participants penalized breaches of temporal and spatial-temporal adjacency to a greater degree than breaches of spatial adjacency and left-to-right direction.


Subject(s)
Child Development/physiology , Executive Function/physiology , Mathematical Concepts , Visual Perception/physiology , Child , Female , Humans , Male
2.
Rev Esp Enferm Dig ; 105(1): 13-7, 2013 Jan.
Article in English | MEDLINE | ID: mdl-23548006

ABSTRACT

BACKGROUND: symptoms attributed to the lactose intolerance are an important public health issue because of their prevalence and social relevance. Also because they may cause undue rejection of dairy products consume with potential health consequences. Transit time is a putative factor implied in the severity of symptoms associated with lactose. OBJECTIVES: to elucidate the relation between orocecal transit time (OCTT) and lactose intolerance symptoms. METHODS: observational study in patients referred to a lactose hydrogen breath test who showed an increase in breath H2 excretion higher than 25 ppm. OCTT was measured with the breath test and symptoms of lactose tolerance with a validated scale. Symptoms were measured twice: before receiving the lactose, inquiring about self perceived symptoms when patients consumed dairy products at home ("home symptoms"), and again after completing the lactose breath test ("test symptoms"). RESULTS: 161 patients were included. There was no correlation between OCTT and home symptoms (r = -0.1). When OCTT was faster than 60 minutes, intensity of "test symptoms" was similar to "home symptoms". However, in patients with normal or slow OCTT, the "home symptoms" were more intense than the "test symptoms" (p < 0.05). At home, symptoms were independent of OCTT but with the lactose test load the symptoms were proportionately more intense with faster OCTT. CONCLUSIONS: in lactose maldigesters, selfreported symptoms of lactose intolerance are more pronounced at home than after a high lactose challenge. Intolerance symptoms that patients attributed to lactose consume at home are due to factors other than fast OCTT.


Subject(s)
Gastrointestinal Transit/physiology , Lactose Intolerance/diagnosis , Lactose Intolerance/physiopathology , Adult , Breath Tests , Cecum , Diagnostic Self Evaluation , Female , Humans , Male , Mouth , Surveys and Questionnaires , Time Factors
3.
Rev. esp. enferm. dig ; 105(1): 13-18, ene. 2013. tab, ilus
Article in Spanish | IBECS | ID: ibc-112268

ABSTRACT

Antecedentes: los síntomas atribuidos a la intolerancia a la lactosa son un importante problema de salud pública. El tiempo de tránsito es un factor implicado en la severidad de los síntomas asociados al consumo de lactosa. Objetivos: elucidar la relación entre el tiempo de tránsito orocecal (TTOC) y los síntomas de intolerancia a la lactosa. Métodos: estudio observacional en pacientes con un test del aliento de hidrógeno con lactosa patológico (excreción de hidrógeno superior a 25 ppm). El TTOC se midió mediante el test del aliento y los síntomas mediante una escala previamente validada. Los síntomas se determinaron dos veces: antes de recibir la lactosa, preguntando acerca de los síntomas en casa cuando se consumen lácteos (“síntomas en casa”), y de nuevo después de completar el test del aliento con lactosa (“síntomas test”). Resultados: se han incluido 161 pacientes. No se observa correlación entre el TTOC y los síntomas en casa (r = -0,1). Cuando el TTOC fue más rápido de 60 minutos, la intensidad de los “síntomas test” fue parecida a la de los “síntomas en casa”. Sin embargo, en los pacientes con TTOC normal o lento, los “síntomas en casa” fueron más intensos que los “síntomas test” (p < 0,05). En casa los síntomas fueron independientes del TTOC mientras que después de la sobrecarga de lactosa los síntomas fueron más intensos cuanto más rápido el TTOC. Conclusiones: los síntomas que refieren las personas con malabsorción de lactosa son más pronunciados en casa que tras una sobrecarga de lactosa. Los síntomas de intolerancia que los pacientes atribuyen al consumo de lactosa en casa no son debidos a un TTOC rápido(AU)


Background: symptoms attributed to the lactose intolerance are an important public health issue because of their prevalence and social relevance. Also because they may cause undue rejection of dairy products consume with potential health consequences. Transit time is a putative factor implied in the severity of symptoms associated with lactose. Objectives: to elucidate the relation between orocecal transit time (OCTT) and lactose intolerance symptoms. Methods: observational study in patients referred to a lactose hydrogen breath test who showed an increase in breath H2 excretion higher than 25 ppm. OCTT was measured with the breath test and symptoms of lactose tolerance with a validated scale. Symptoms were measured twice: before receiving the lactose, inquiring about self perceived symptoms when patients consumed dairy products at home (“home symptoms”), and again after completing the lactose breath test (“test symptoms”). Results: 161 patients were included. There was no correlation between OCTT and home symptoms (r = -0.1). When OCTT was faster than 60 minutes, intensity of “test symptoms” was similar to “home symptoms”. However, in patients with normal or slow OCTT, the “home symptoms” were more intense than the “test symptoms” (p < 0.05). At home, symptoms were independent of OCTT but with the lactose test load the symptoms were proportionately more intense with faster OCTT. Conclusions: in lactose maldigesters, selfreported symptoms of lactose intolerance are more pronounced at home than after a high lactose challenge. Intolerance symptoms that patients attributed to lactose consume at home are due to factors other than fast OCTT(AU)


Subject(s)
Humans , Male , Female , Adult , Gastrointestinal Transit/physiology , Lactose Intolerance/diagnosis , Lactose Intolerance/therapy , Malabsorption Syndromes/complications , Malabsorption Syndromes/diagnosis , Propantheline/therapeutic use , Lactose Tolerance Test/instrumentation , Lactose Tolerance Test/methods , Lactose Intolerance/physiopathology , Public Health/trends , Hydrogen , Surveys and Questionnaires , Predictive Value of Tests , Lactose Tolerance Test/standards , Lactose Tolerance Test/trends , Lactose Tolerance Test
4.
J Exp Child Psychol ; 114(1): 35-46, 2013 Jan.
Article in English | MEDLINE | ID: mdl-23063094

ABSTRACT

In this study, the development of comprehension of essential and nonessential aspects of counting is examined in children ranging from 5 to 8 years of age. Essential aspects, such as logical rules, and nonessential aspects, including conventional rules, were studied. To address this, we created a computer program in which children watched counting errors (abstraction and order irrelevance errors) and pseudoerrors (with and without cardinal value errors) occurring during a detection task. The children judged whether the characters had counted the items correctly and were asked to justify their responses. In general, our data show that performance improved substantially with age in terms of both error and pseudoerror detection; furthermore, performance was better with regard to errors than to pseudoerrors as well as on pseudoerror tasks with cardinal values versus those without cardinal values. In addition, the children's justifications, for both the errors and pseudoerrors, made possible the identification of conventional rules underlying the incorrect responses. A particularly relevant trend was that children seem to progressively ignore these rules as they grow older. Nevertheless, this process does not end at 8 years of age given that the conventional rules of temporal and spatial adjacency were present in their judgments and were primarily responsible for the incorrect responses.


Subject(s)
Comprehension/physiology , Judgment/physiology , Mathematical Concepts , Age Factors , Child , Child Development/physiology , Child, Preschool , Cognition/physiology , Female , Humans , Male , Task Performance and Analysis
5.
An. psicol ; 27(3): 631-638, oct.-dic. 2011. tab, graf
Article in English | IBECS | ID: ibc-94300

ABSTRACT

La mayoría de las investigaciones sobre la conciencia étnica y el prejuicio en niños se ha basado en estudios transversales, por lo que tenemos poca información sobre los cambios intraindividuales que ocurren en esta área de desarrollo. ¿Hay una secuencia de desarrollo estable de los diferentes componentes de la conciencia étnica? ¿La preferencia por el endogrupo precede al rechazo del exogrupo, como sugieren los estudios transversales? ¿Y mantienen los niños la misma orientación afectiva hacia diferentes exogrupos? En este artículo se presenta un estudio longitudinal con 50 niños españoles de 4 a 5 años (primera medida) y de 5 a 6 años (segunda medida) en el que se evaluaron varios aspectos de su conciencia étnica y de sus actitudes hacia cuatro grupos (españoles, latinoamericanos, africanos y asiáticos), en un contexto de juego de ordenador. Los resulta-dos mostraron una significativa positividad hacia el endogrupo, pero ausencia de negatividad hacia los exogrupos, tanto en el primer tiempo de medida como en el segundo. De hecho, no hubo diferencias en las atribuciones negativas de los niños al endogrupo y a los exogrupos. Por otra parte, los análisis longitudinales mostraron que la mayoría de los niños no cambió la intensidad de su orientación afectiva hacia cada grupo étnico, un tema que ha recibido poca atención en estudios previos (AU)


Most previous research on children’s ethnic awareness and prejudice has been based on cross-sectional studies; hence we have little in-formation on the intra-individual changes that occur in this area of development. Is there a stable developmental sequence of the different components of ethnic awareness? Does in-group preference precede out-group rejection, as cross-sectional studies do suggest? And do children maintain the same affective orientation toward different out-groups? We con-ducted a longitudinal study with 50 Spanish children aged 4 to 5 years (first measure) and 5 to 6 years (second measure). We assessed several aspects of their ethnic awareness and attitudes toward four groups (Spaniards, Latin Americans, Africans and Asians), within a computer-game context. Results showed a significant in-group positivity but a lack of out-group negativity, both at time 1 and 2. In fact, children’s negative attributions to the in-group and to the out-groups did not differ. On the other hand, the longitudinal analyses revealed that most children did not change the intensity of their affective orientation to each group, an issue that has received little attention in previous studies (AU)


Subject(s)
Humans , Male , Female , Child, Preschool , Child , 35172 , Attitude/ethnology , Child , Child Guidance/education , Child Guidance/ethics , Ethnicity/education , Ethnicity/psychology , Prejudice , Child Guidance/statistics & numerical data , Child Guidance/standards , Child Guidance/trends , Hispanic or Latino/classification , Hispanic or Latino/ethnology , Asian/classification , Black or African American/classification
6.
An. psicol ; 27(3): 670-678, oct.-dic. 2011. tab, graf
Article in Spanish | IBECS | ID: ibc-94305

ABSTRACT

En este trabajo analizamos las actitudes de 600 niños españoles de 6 a 12 años hacia 8 potenciales compañeros que diferían entre sí en dos características físicas relevantes en nuestra cultura: el color de la piel y la complexión física. Con este fin, diseñamos una prueba con diversas tareas que nos permitió conocer sus preferencias para realizar distintas actividades, así como los patrones de atribución de adjetivos (estereotipos) dirigidos hacia los distintos tipos de compañeros. Los resultados mostraron un fuerte efecto de la complexión física en todas las medidas actitudinales consideradas. Por su parte, el color de piel también determinó las respuestas de los participantes, pero en menor medida que el peso. Además, ambos tipos de prejuicios siguieron cursos evolutivos muy diferentes a lo largo de toda la Educación Primaria: los sesgos relacionados con el color de la piel se atenuaron significativamente conforme la edad de los participantes aumentaba, en concordancia con la mayoría de los estudios previos en esta área. En cambio, los sesgos relacionados con el sobrepeso se mantuvieron relativamente constantes en estas edades en una de las medidas e incluso, en la otra, se incrementaron. Los resultados nos indican en qué medida el sobrepeso puede ser fuente de discriminación y rechazo desde los primeros años de escolarización formal (AU)


This paper analyzes the attitudes of 600 Spanish children from 6 to 12 years to 8 potential mates that differed in two important physical characteristics in our culture: the color of the skin and physique. To this end, we designed a test with various tasks that allowed us know your preferences for different activities, and attribution patterns of adjectives (stereotypes) directed toward different types of peers. The results showed a strong effect of physique in all attitudinal measures considered. For its part, the skin color also determined the responses of the participants, but less so than weight. Furthermore, both types of prejudice followed very different developmental courses throughout Primary Education: biases associated with skin color has faded significantly as the age of participants increased, in line with most previous studies on this area. Instead, biases related to being overweight remained relatively constant at these ages in one of the measures and even, on the other, increased. The results indicate the extent to which being overweight can be a source of discrimination and rejection from the first years of formal schooling (AU)


Subject(s)
Humans , Male , Female , Child , Ethnicity/education , Ethnicity/ethnology , Black People/education , Black People/ethnology , Prejudice , Stereotyping , Race Relations/psychology , Ethnicity/psychology , Ethnicity/statistics & numerical data , Black People/statistics & numerical data , Race Relations/history , Race Relations/trends
7.
Br J Dev Psychol ; 29(Pt 3): 593-611, 2011 Sep.
Article in English | MEDLINE | ID: mdl-21848748

ABSTRACT

The general purpose of this study was to analyse the developmental relations between the early forms of ethnic attitudes, and the classification abilities of the young child. We designed new cognitive tasks within a detection paradigm adapted to preschoolers and attitudinal tasks that were presented as games in a computer screen. Participants were 75 majority-group children of 3, 4, and 5 years of age. Children's preferences and positive/negative attitudes towards the in-group (Spaniards) and three out-groups (Latin-Americans, Africans, and Asians) were measured. The results showed a remarkable preference and positivity for the in-group, but not out-group derogation. Children's cognitive performance, to a greater extent than their age, was positively associated with in-group favouritism and positivity. On the other hand, we found some interesting differences and developmental changes in children's positive orientation to the out-groups that are discussed in the last section.


Subject(s)
Attitude , Cognition , Ethnicity/psychology , Social Identification , Child, Preschool , Choice Behavior , Female , Humans , Judgment , Male , Pattern Recognition, Visual , Play and Playthings , Semantics , Social Desirability , Spain
8.
Clin Gastroenterol Hepatol ; 8(7): 581-6, 2010 Jul.
Article in English | MEDLINE | ID: mdl-20385250

ABSTRACT

BACKGROUND & AIMS: Symptomatic lactose intolerance is common; however, abdominal symptoms that patients experience after ingestion of lactose-containing foods can have causes beyond lactose malabsorption. We aimed to determine whether symptoms that patients usually attribute to lactose intolerance are comparable to symptoms provoked by a controlled lactose challenge and whether these symptoms are related to lactose absorption capacity. METHODS: We performed an observational, prospective, transverse study of 353 patients referred for a lactose hydrogen breath test (HBT). Patients completed a validated questionnaire about symptoms associated with consumption of dairy products at home (home symptoms). After a 50-g lactose breath test, they completed the same questionnaire again (lactose challenge symptoms). Patients were assigned to groups of absorbers or malabsorbers according to HBT results and tolerants or intolerants according to the results of the questionnaire. RESULTS: The total symptom score was significantly higher for home symptoms than for the lactose challenge (16 vs 8, P < .01). Symptoms perceived at home were reported to be more intense than those that followed the lactose challenge for lactose absorbers compared with malabsorbers (16 vs 4, P < .01) and lactose tolerants compared with intolerants (12 vs 2, P < .05). Overperception of lactose intolerance at home was similar in men and women. CONCLUSIONS: Daily life symptoms that patients associate with lactose intolerance are often unrelated to lactose malabsorption. Even among true lactose malabsorbers, symptom recall tends to be amplified by the patient. Thus, conventional anamnesis is a highly unreliable tool to establish symptomatic lactose malabsorption.


Subject(s)
Lactose Intolerance/diagnosis , Lactose Intolerance/psychology , Lactose/metabolism , Perception , Adult , Breath Tests , Cross-Over Studies , Female , Humans , Lactose Intolerance/pathology , Male , Prospective Studies , Surveys and Questionnaires
9.
An. psicol ; 24(2): 201-212, dic. 2008. tab
Article in Es | IBECS | ID: ibc-69410

ABSTRACT

Los problemas de división con resto son especialmente complejos, como han mostrado numerosos estudios. El objetivo de esta investigación era establecer si las dificultades de los estudiantes procedían de una representación inicial inapropiada o de una interpretación inadecuada de las respuestas numéricas. También queríamos determinar si los tipos de resto se podían agrupar en dos bloques, dependiendo de que la respuesta correspondiese directamente a los términos de la división o no. Evaluamos 49 estudiantes de secundaria con una edad media de 12 años;10 meses. Los participantes resolvieron problemas de Grupos Iguales Partitivos y de Medida con cuatro Tipos de Resto: Resto-no-Divisible, Resto-Divisible, Resto-Resultado y Reajustar-Cociente-Incrementándolo-Parcialmente. Nuestros datos mostraron que: (a) la elección de la división como procedimien-to de resolución fue muy elevada en ambos Modelos de División, aunque los problemas Partitivos fueron más fáciles que los de Medida; (b) el porcentaje de interpretaciones correctas fue superior a los encontrados en otras investigaciones; y (c) cuando la respuesta consistía en el cociente o el resto el éxito fue superior que cuando había que Reajustar-Cociente-Incrementándolo-Parcialmente. Para finalizar, la principal dificultad de los estudiantes al resolver estos problemas parece girar en torno a la representación inicial deficitaria del problema


Division-With-Remainder problems are particularly complex as suggested in many works. The aim of the present research was to establish whether students’ difficulties in these problems came from an inadequate initial representation or from an inadequate final interpretation of the numerical answers. We also wanted to determine whether types of remainders could be grouped into two blocks depending on whether the answer was directly matched to one of the terms of the division or not. To this end, we tested forty-nine secondary students with a mean age of 12 years and 10 months. The participants solved Partitive and Quotitive Equal-Groups problems involving four Types of Remainder: Remainder-Not-Divisible, Remainder-Divisible, Remainder-as-the-Result, and Readjusted-Quotient-by-Partial-Increments. Our data showed that: (a) although the selection of division as the resolution procedure was very high in both Models of Division, Partitive problems were easier than Quotitive ones; (b) the percentage of correct interpretations was higher than the percentages reported in other researches; and (c) success in problems whose answers were the quotient or the remainder was higher than in Readjusted-Quotient-by-Partial-Increments problems. To conclude, the main difficulty of students when solving Division-With-Remainder problems seems to be in the inadequate initial representation of the problem


Subject(s)
Humans , Male , Female , Child , Adolescent , Mathematics , Psychology, Educational/classification , Psychology, Educational/methods , Teaching/methods , Problem-Based Learning/methods , Students/psychology , Analysis of Variance , Comprehension , Psychology, Adolescent/methods , Psychology, Adolescent/standards , Psychology, Educational/instrumentation , Psychology, Educational/organization & administration , Psychology, Educational/standards
10.
An. psicol ; 24(2): 240-252, dic. 2008. ilus, tab
Article in Es | IBECS | ID: ibc-69413

ABSTRACT

Los niños pequeños tienen un conjunto de habilidades matemáticas que les permite enfrentarse con éxito a problemas con estructura aditiva y multiplicativa. Con objeto de determinar el alcance de esta afirmación, hemos evaluado a los mismos niños en dos ocasiones (i.e., cuando tenían 4-5 años y posteriormente a los 5-6 años) en problemas de Cambio y Grupos Iguales, usando objetos para facilitar el proceso de representación de las cantidades. Los resultados mostraron que: (1) el nivel de rendimiento de los niños, independientemente del momento de medición, era muy elevado en todos los problemas; (2) tan sólo se observó un cierto retroceso en el rendimiento en los problemas de sustracción; (3) en todos los problemas los procedimientos de resolución se basaban en general en la representación directa de las cantidades; (4) las estrategias de conteo aparecían exclusivamente en los problemas de adición y sustracción y las de conocimientos derivados, principalmente, en los de multiplicación y división; (5) la variabilidad de las estrategias dependía del tipo de operación y momento de medición y finalmente, (6) el cambio de estrategias era gradual y no abrupto


Young children posses a wide range of arithmetical abilities that enable them to successfully face word problem, with additive and multiplicative structures. To test this, we have assessed the participants twice (i.e., when they were 4 to 5 years old and when they were 5 to 6 years old) with Change and Equal Groups problems, where objects were available to ease the representation of the quantities of the problems. The result showed that: (1) the level of children’s success was very high, regardless the moment of assessment and the kind of problem; (2) only the subtraction problems registered a decrease during the second assessment; (3) the procedures of resolution were mainly based on the direct representation of the quantities for all kind of problems; (4) the counting strategies were used only in the additive and subtractive problems, while the derived fact strategies were mainly applied in the multiplication and division problems; (5) the variability in the use of the strategies was affected by the kind of operation involved in the problem and the moment of the assessment; and finally (6) strategy change seemed to be gradual rather than abrupt


Subject(s)
Humans , Male , Female , Child , Child, Preschool , Health Strategies , Competency-Based Education/organization & administration , Competency-Based Education/standards , Psychology, Educational/methods , Efficiency , Adaptation, Psychological/physiology , Analysis of Variance , Competency-Based Education/classification , Competency-Based Education/methods , Competency-Based Education/trends , Psychology, Educational/organization & administration , Psychology, Educational/standards , Social Adjustment
11.
Gac Sanit ; 21(1): 84-7, 2007.
Article in Spanish | MEDLINE | ID: mdl-17306193

ABSTRACT

We describe the design and the response indicators in a cross sectional study to estimate several factors associated with cardiovascular risk in the population of Castile and Leon. A sample of 4,950 individuals aged 15 years and above was obtained in two stages: in the first stage, 198 primary care physicians were selected and in the second stage a sample of 25 persons from each primary care physician's list was obtained. The response rate was 98% among primary care physicians and 80% among the population. Statistically significant differences were found in age distribution between the frame sample and the definitive sample. After applying design adjustments, only the group aged 35-64 years was significantly overdimensioned. Access to the general population in primary health care is a feasible and effective procedure. A high response rate contributes to the validity of the information.


Subject(s)
Cardiovascular Diseases/epidemiology , Epidemiologic Research Design , Primary Health Care/organization & administration , Adolescent , Adult , Age Distribution , Aged , Aged, 80 and over , Cross-Sectional Studies , Feasibility Studies , Female , Humans , Male , Middle Aged , Risk Factors , Sampling Studies , Spain/epidemiology
12.
Gac. sanit. (Barc., Ed. impr.) ; 21(1): 84-87, ene. 2007. tab
Article in Es | IBECS | ID: ibc-053939

ABSTRACT

Se describe el diseño y los indicadores de respuesta de un estudio transversal para estimar diferentes parámetros del riesgo cardiovascular en la población de Castilla y León. Se obtuvo una muestra de 4.950 personas de 15 y más años de edad en dos etapas: en la primera etapa se eligieron 198 médicos de atención primaria, y en la segunda se seleccionó una muestra de 25 personas del cupo de cada médico. Las tasas de respuesta de los médicos alcanzaron el 98%, y las de la población superaron el 80%. Se encontraron diferencias estadísticamente significativas en la distribución por edad del marco muestral y la muestra definitiva. Después de realizar las ponderaciones derivadas del diseño, sólo el grupo de edad de 35-64 años se encuentra significativamente sobredimensionado. El acceso a la población general en atención primaria es un procedimiento factible y eficaz. La alta tasa de respuesta contribuye a la validez de la información


We describe the design and the response indicators in a cross sectional study to estimate several factors associated with cardiovascular risk in the population of Castile and Leon. A sample of 4,950 individuals aged 15 years and above was obtained in two stages: in the first stage, 198 primary care physicians were selected and in the second stage a sample of 25 persons from each primary care physician's list was obtained. The response rate was 98% among primary care physicians and 80% among the population. Statistically significant differences were found in age distribution between the frame sample and the definitive sample. After applying design adjustments, only the group aged 35-64 years was significantly overdimensioned. Access to the general population in primary health care is a feasible and effective procedure. A high response rate contributes to the validity of the information


Subject(s)
Male , Female , Adolescent , Adult , Middle Aged , Aged , Humans , Cardiovascular Diseases/epidemiology , Epidemiologic Research Design , Primary Health Care/organization & administration , Age Distribution , Cross-Sectional Studies , Feasibility Studies , Risk Factors , Sampling Studies , Spain/epidemiology
13.
Int J Antimicrob Agents ; 23(5): 487-93, 2004 May.
Article in English | MEDLINE | ID: mdl-15120728

ABSTRACT

The Acinetobacter calcoaceticus-Acinetobacter baumannii complex includes some of the most clinically relevant species of the genus Acinetobacter due to their capacity to cause epidemic nosocomial outbreaks as well as their increasing resistance to antibiotics. Susceptibility of Acinetobacter strains varies greatly depending on origin, thus highlighting the importance of local analyses of susceptibility profiles. Two hundred twenty-one strains of the A. calcoaceticus-A. baumannii complex were identified using biochemical tests and were biotyped. Strain susceptibility to imipenem, meropenem, colistin and sulbactam was studied using agar dilution. Eight different biotypes were found, type 1 accounting for 69.2% of the strains. MIC(50) and MIC(90) to imipenem, meropenem, colistin and sulbactam were 4 and 8 mg/l, 16 and 32 mg/l, 0.5 and 1mg/l, and 8 and 16 mg/l, with susceptibility rates of 64.3, 22.6, 98.2 and 73.8%, respectively. Biotype 1 was the most resistant. A statistically significant difference was observed for the mean MIC of the four predominant biotypes to imipenem, meropenem and sulbactam but not to colistin.


Subject(s)
Acinetobacter/drug effects , Colistin/pharmacology , Imipenem/pharmacology , Sulbactam/pharmacology , Thienamycins/pharmacology , Acinetobacter/classification , Acinetobacter/isolation & purification , Acinetobacter Infections/microbiology , Acinetobacter baumannii/classification , Acinetobacter baumannii/drug effects , Acinetobacter baumannii/isolation & purification , Acinetobacter calcoaceticus/classification , Acinetobacter calcoaceticus/drug effects , Acinetobacter calcoaceticus/isolation & purification , Anti-Bacterial Agents/pharmacology , Bacterial Typing Techniques , Drug Resistance, Microbial , Humans , Meropenem , Microbial Sensitivity Tests
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