Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 2 de 2
Filter
Add more filters










Language
Publication year range
1.
Rev. esp. enferm. dig ; 115(12): 724-725, Dic. 2023. ilus
Article in English | IBECS | ID: ibc-228715

ABSTRACT

We are writing to make endoscopists aware of the paramount of a prompt diagnosis of gastrointestinal Kaposi sarcoma (GI-KS). Patients with GI involvement have a two to five times higher risk of death and will benefit from chemotherapy to improve their survival. However, current evidence found that one out of three patients might have a false negative result even with HHV-8 since other entities such as gastrointestinal stromal tumors, angiosarcoma, and lymphoma shared macroscopic and histopathological characteristics. These cause a delay in treatment and significantly worsen the prognosis. We observed a trend for a positive diagnosis from ulcers and nodules. To our knowledge, this is the largest cohort of patients with GI-KS in the world. Our study suggests that in cases where a complete immunochemistry panel for KS is not available, HHV-8 remains as a bare minimum. However, other gastrointestinal lesions shared histopathological characteristics. Therefore, we suggest taking biopsies from nodular and ulcer-type lesions to increase the probability to establish a histopathological diagnosis.(AU)


Subject(s)
Humans , Sarcoma, Kaposi/diagnosis , Herpesvirus 8, Human , Endoscopy, Gastrointestinal , Gastrointestinal Stromal Tumors , Hematoxylin/administration & dosage , Eosine Yellowish-(YS)/administration & dosage , Gastrointestinal Diseases , Inpatients , Physical Examination
2.
Rev Esp Enferm Dig ; 115(12): 724-725, 2023 Dec.
Article in English | MEDLINE | ID: mdl-36866841

ABSTRACT

We are writing to make endoscopists aware of the paramount of a prompt diagnosis of gastrointestinal Kaposi sarcoma (GI-KS). Patients with GI involvement have a two to five times higher risk of death and will benefit from chemotherapy to improve their survival. However, current evidence found that one out of three patients might have a false negative result even with HHV-8 since other entities such as gastrointestinal stromal tumors, angiosarcoma, and lymphoma shared macroscopic and histopathological characteristics. These cause a delay in treatment and significantly worsen the prognosis. We observed a trend for a positive diagnosis from ulcers and nodules. To our knowledge, this is the largest cohort of patients with GI-KS in the world. Our study suggests that in cases where a complete immunochemistry panel for KS is not available, HHV-8 remains as a bare minimum. However, other gastrointestinal lesions shared histopathological characteristics. Therefore, we suggest taking biopsies from nodular and ulcer-type lesions to increase the probability to establish a histopathological diagnosis.


Subject(s)
Gastrointestinal Stromal Tumors , Herpesvirus 8, Human , Sarcoma, Kaposi , Humans , Sarcoma, Kaposi/diagnosis , Sarcoma, Kaposi/pathology , Endoscopy, Gastrointestinal , Prognosis
SELECTION OF CITATIONS
SEARCH DETAIL
...