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1.
Neurocirugia (Astur) ; 14(5): 385-91, 2003 Oct.
Article in Spanish | MEDLINE | ID: mdl-14603385

ABSTRACT

INTRODUCTION: Surgical treatment of multiple intracranial aneurysms is always a complex task. OBJECTIVE: To analyze aneurysms characteristics, therapeutic possibilities and surgical outcomes in a series of patients with multiple intracranial aneurysms. PATIENTS AND METHOD: Among 514 patients with intracranial aneurysms, there were 113 with multiple aneurysms (21.5%) and 256 sacs: 244 located at the carotid system and 12 in the vertebrobasilar system. Patients were classified in three groups according to Orz criteria. Surgical treatment was performed in one or two stage operations. Patients were at I or II Grades of the World Federation Scale. The Glasgow Outcome Scale was used for evaluating surgical results. RESULTS: Patients sacs rate was 2.3. The location of aneurysms was high in the posterior communicating artery and very low at the middle cerebral artery. 100% of the lesions in Orz group 1, 82% in group 2 and 33% in group 3 were operated on in one stage operation. Postoperative follow-up showed that 79 % of the patients made a completely recovery. Mortality rate was 4.4%. CONCLUSIONS: Results were determined by the peculiar characteristics of this series, good preoperative condition and high proportion of one-stage operations.


Subject(s)
Intracranial Aneurysm/surgery , Adolescent , Adult , Aged , Female , Humans , Intracranial Aneurysm/complications , Intracranial Aneurysm/pathology , Male , Middle Aged
2.
Rev Neurol ; 37(8): 711-6, 2003.
Article in Spanish | MEDLINE | ID: mdl-14593626

ABSTRACT

INTRODUCTION: Petrous and petroclival lesions may be surgically treated with combinations of suprainfratentorial presigmoideo approach and microsurgical techniques. OBJECTIVE: To demonstrate the utility and to present our surgical experiences with this approach. PATIENTS AND METHODS: Thirteen patients with lesions of the clival, petrous region and of the cerebellopontine angle with extension toward the anterior portion of brainstem were taken to the operative room. There were nine women and four men. Eleven were adults and two children. The main clinical manifestations were headache (100%), dysfunction of cranial nerves (90%), ataxia (90%) hemiparesis (75%). There was papiledema in 45%. Petroclival meningiomas and schwannomas were the more frequent lesions. There were three patients with intraxial brainstem tumors and two arteriovenous malformations. There were not aneurysms. We performed nine retrolaberintic, three translaberintic and one transcochlear approach. RESULTS: There was not severe incapacity, vegetative or dead patients. The surgical complications were facial nerve paresis (31%), cerebrospinal fluid leak (23%), decreased gag reflex (15%), abducens nerve paresis, hemiparesis and Claude Bernard Horner syndrome (8%). 50% of these complications disappeared three months later. CONCLUSIONS: The suprainfratentorial presigmoidal approach and their surgical variations could be utilized to obtaining a low morbimortality, in the treatment of different neoplasm and vascular diseases of the petrous and petroclival region.


Subject(s)
Brain Neoplasms , Cerebellopontine Angle , Cranial Fossa, Posterior , Craniotomy/methods , Petrous Bone , Skull Base Neoplasms , Adult , Brain Neoplasms/pathology , Brain Neoplasms/surgery , Brain Stem/pathology , Brain Stem/surgery , Cerebellopontine Angle/pathology , Cerebellopontine Angle/surgery , Child , Cranial Fossa, Posterior/pathology , Cranial Fossa, Posterior/surgery , Female , Humans , Male , Petrous Bone/pathology , Petrous Bone/surgery , Skull Base Neoplasms/pathology , Skull Base Neoplasms/surgery , Treatment Outcome
3.
Rev. neurol. (Ed. impr.) ; 37(8): 711-716, 16 oct., 2003. ilus, tab
Article in Es | IBECS | ID: ibc-28215

ABSTRACT

Introducción. Las lesiones de la región petrosa y clival pueden intervenirse quirúrgicamente con la combinación del abordaje suprainfratentorial presigmoideo (ASITPS) y de las actuales técnicas microquirúrgicas. Objetivos. Demostrar la utilidad y presentar nuestras experiencias con este abordaje . Pacientes y métodos. Se llevaron al quirófano 13 pacientes con lesiones de la región clival, petrosa y del ángulo pontocerebeloso con extensión hacia la porción anterior del tronco. Hubo nueve mujeres y cuatro hombres; 11 eran adultos y dos niños. Las principales manifestaciones clínicas fueron la cefalea (100 por ciento), la disfunción de nervios craneales (90 por ciento), la ataxia (90 por ciento) y los déficit motores (75 por ciento). Hubo papiledema en el 45 por ciento. Los meningiomas petroclivales y los schwannomas fueron las lesiones más frecuentes. Hubo tres pacientes con neoplasias intraaxiales de tronco cerebral y dos malformaciones arteriovenosas. No hubo lesiones aneurismáticas. Realizamos nueve abordajes retrolaberínticos, tres translaberínticos y uno transcoclear. Resultados. No hubo pacientes gravemente incapacitados, vegetativos o fallecidos. Las complicaciones quirúrgicas fueron paresia facial periférica (31 por ciento), fístula de LCR (23 por ciento), reducción del reflejo de deglución (15 por ciento), paresia del nervio abducens (8 por ciento), hemiparesia y síndrome de Claude Bernard Horner (8 por ciento). El 50 por ciento de estas complicaciones desaparecieron en menos de tres meses. Conclusiones. El ASITPS y sus variantes quirúrgicas pueden utilizarse en el tratamiento quirúrgico de enfermedades tumorales y vasculares diversas de esa región y obtener una morbimortalidad baja (AU)


Introduction. Petrous and petroclival lesions may be surgically treated with combinations of suprainfratentorial presigmoideo approach and microsurgical techniques. Objectives, To demonstrate the utility and to present our surgical experiences with this approach. Patients and methods. Thirteen patients with lesions of the clival, petrous region and of the cerebellopontine angle with extension toward the anterior portion of brainsteam were taken to the operative room. There were nine women and four men. Eleven were adults and two children. The main clinical manifestations were headache (100%), dysfunction of cranial nerves (90%), ataxia (90%) hemiparesis (75%). There was papiledema in 45%. Petroclival meningiomas and schwannomas were the more frequent lesions. There were three patients with intraxial brainsteam tumors and two arteriovenous malformations. There were not aneurysms. We performed nine retrolaberintic, three translaberintic and one transcochlear approach. Results. There was not severe incapacity, vegetative or dead patients. The surgical complications were facial nerve paresis (31%), cerebrospinal fluid leak (23%), decreased gag reflex (15%), abducens nerve paresis, hemiparesis and Claude Bernard Horner syndrome (8%). 50% of these complications disappeared three months later. Conclusions. The suprainfratentorial presigmoidal approach and their surgical variations could be utilized to obtaining a low morbimortality, in the treatment of different neoplasm and vascular diseases of the petrous and petroclival region (AU


Subject(s)
Child , Adult , Male , Female , Humans , Petrous Bone , Cranial Fossa, Posterior , Skull Base Neoplasms , Brain Neoplasms , Cerebellopontine Angle , Treatment Outcome , Brain Stem , Craniotomy
4.
Neurocir. - Soc. Luso-Esp. Neurocir ; 14(5): 385-391, oct. 2003.
Article in Es | IBECS | ID: ibc-26433

ABSTRACT

Introducción: El tratamiento quirúrgico de los aneurismas intracraneales múltiples sigue siendo un problema complejo. Objetivos: Analizar las características de los aneurismas múltiples, las posibilidades terapéuticas y los resultados del tratamiento quirúrgico. Pacientes y Método: De un total de 514 pacientes con aneurismas intracraneales hubo 113 con aneurismas múltiples (21.5 por ciento) y 256 sacos: 244 del sistema carotídeo y 12 del sistema vertebrobasilar. Los pacientes fueron clasificados en tres grupos siguiendo los criterios de Orz. El método de tratamiento fue la intervención quirúrgica en uno o dos tiempos. Los pacientes se encontraban en grado I y II de la Escala de la Federación Mundial. Los resultados se evaluaron con la Escala de Pronósticos de Glasgow. Resultados: El promedio fue de 2.3 sacos por paciente. Fue elevada la proporción de lesiones en la región de la comunicante posterior y baja en la arteria cerebral media. El 54 por ciento de los pacientes correspondió al grupo 1 de Orz, el 35 por ciento al grupo 2 y el 11 por ciento al grupo 3. El 100 por ciento de las lesiones del grupo 1, el 82 por ciento de las lesiones del grupo 2 y el 33 por ciento de las lesiones del grupo 3 se intervinieron en un solo tiempo quirúrgico. El 79 por ciento de los pacientes obtuvieron una recuperación completa. La mortalidad quirúrgica fue del 4.4 por ciento. Conclusiones: Las características particulares de las lesiones aneurismáticas encontradas en esta serie, el buen estado clínico preoperatorio y la elevada proporción de pacientes intervenidos en un solo abordaje determinaron estos resultados (AU)


Subject(s)
Middle Aged , Adolescent , Adult , Aged , Male , Female , Humans , Intracranial Aneurysm
5.
Neurocirugia (Astur) ; 14(4): 302-8, 2003 Sep.
Article in Spanish | MEDLINE | ID: mdl-14506553

ABSTRACT

INTRODUCTION: Distal anterior cerebral artery is the portion of the anterior cerebral artery located distal to the anterior communicating artery. Aneurysms of that territory represent 0.35 - 4.5% of all intracranial aneurysms. MATERIAL AND METHODS: 524 patients with intracranial aneurysms were operated on between January 1981 and April 2002. We treated 20 patients with distal anterior cerebral artery aneurysms. They were classified as infracallosa, located at the genu of the corpus callosum and supracallosal. Specialized anesthetic methods, Sugita head holder, and microsurgical techniques were utilized. Approaches were modified regarding aneurysm localization and multiplicity. Patients were evaluated six months after surgery. Glasgow Outcome Scale was applied. RESULTS: Thirteen patients (65%) were between 31 and 45 years of age. All were operated on at Grade I or II of the World Federation Neurological Surgeon Scale. There were multiple aneurysms in 35% of the cases. All of the aneurysms were 11 mm long or less in diameter. The segment of the distal anterior cerebral artery next to the genu of the corpus callosum was the most commonly involved (65%). 16 (80%) patients made a complete postoperative recovery of. There were not deaths. CONCLUSION: Distal anterior, cerebral artery aneurysms were not frequent and they needed special management. Their high tendency to multiplicity and early bleeding were two main characteristics. As they are midline located, they permit to perform small size craniotomy. Cerebral retractors were avoided to reduce postoperative morbidity.


Subject(s)
Intracranial Aneurysm/surgery , Adolescent , Adult , Female , Humans , Male , Middle Aged , Neurosurgical Procedures/methods
6.
Neurocir. - Soc. Luso-Esp. Neurocir ; 14(4): 302-308, sept. 2003.
Article in Es | IBECS | ID: ibc-26421

ABSTRACT

Introducción. La arteria cerebral anterior distal es el segmento de la arteria cerebral anterior más allá de la comunicante anterior. Los aneurismas de este territorio representan el 0.35 - 4.5 por ciento de todos los aneurismas intracraneales. Material y Métodos. De un total de 524 pacientes con aneurismas intracraneales, operados entre Enero de 1981 y Abril de 2002, hubo 20 pacientes con aneurismas de la arteria cerebral anterior distal. Los aneurismas se clasificaron en infracallosos, de la rodilla del cuerpo calloso, y supracallosos. Se utilizó manejo anestésico especializado, soporte craneal de Sugita y técnicas microneuroquirúrgicas. El abordaje utilizado varió con la localización del saco y la multiplicidad. El seguimiento postoperatorio se desarrolló en Terapia Intensiva. Los pacientes fueron evaluados seis meses después de la intervención quirúrgica. Resultados. Trece pacientes (65 por ciento) se encontraban entre los 31 y 45 años. Todos fueron intervenidos en grado I o II de la Federación Mundial. El 35 por ciento tenía sacos múltiples. Todos los aneurismas tenían 11 mm o menos de diámetro mayor. En el segmento de la arteria cerebral anterior, próximo a la rodilla del cuerpo calloso, fue donde se encontraron más sacos aneurismáticos (65 por ciento). En 16 pacientes (80 por ciento) hubo recuperación postoperatorio completa y no hubo fallecidos. Conclusiones. Los aneurismas de la arteria cerebral anterior distal son infrecuentes y requieren de un manejo especial. Tienen tendencia a la multiplicidad y al sangrado precoz. Son sacos localizados en la línea media, en el espacio interhemisférico, lo que permite utilizar craneotomías pequeñas. Debe evitarse el uso de espátulas cerebrales (AU)


Subject(s)
Middle Aged , Adult , Adolescent , Male , Female , Humans , Neurosurgical Procedures , Intracranial Aneurysm
7.
Rev Neurol ; 37(2): 112-7, 2003.
Article in Spanish | MEDLINE | ID: mdl-12938068

ABSTRACT

INTRODUCTION: It is considered multiple intracranial aneurysms when a patient harbors two or more intracranial aneurysms. OBJECTIVE: To analyze clinical characteristic and microneurosurgical results of patients with multiple intracranial aneurysms attended in Camagüey. PATIENTS AND METHODS: Between 524 patients operated on to clip aneurysms, we searched 113 patients with multiple intracranial aneurysms. Patients were operated on by microneurosurgical methods and specialized neuroanesthesia. We performed one or two stage operations. Patients were evaluated three month later with Glasgow Outcome scale. RESULTS: There were 21.5% of multiple aneurysms. Age average was 46 years. There were 85 (75%) women and 28 (25%) men. Associated diseases were high blood pressure, carotid fibromuscular dysplasia and familiar aneurysms. There were 264 aneurysms: 252 at the carotid system and 12 at the vertebrobasilar circulation. Sacs average per patients was 2.3. There were 36% of bilateral aneurysms and 30% of symmetric or mirror sacs. Nehls algorithm permitted to localize symptomatic lesions at: posterior communicating region, anterior cerebral anterior communicating artery, basilar bifurcation, ophthalmic region, and middle cerebral artery. We utilized 128 surgical procedures and two stage operations were applied in 15 patients. 90% of aneurysms were clipped. Ninety patients (79%) obtained complete recuperation, 15 (12%) partial incapacity; 3 (4%) severe incapacity and there were not vegetative patients. Five patients died and the mortality rate was 4.4%. CONCLUSION: Multiple intracranial aneurysms are complex lesions but each one has a similar behavior to sporadic aneurysms. Association to different medical conditions is frequent and microneurosurgery offers good results.


Subject(s)
Intracranial Aneurysm/epidemiology , Adult , Aged , Aged, 80 and over , Aneurysm, Ruptured/complications , Aneurysm, Ruptured/epidemiology , Aneurysm, Ruptured/surgery , Comorbidity , Cuba/epidemiology , Female , Glasgow Coma Scale , Humans , Intracranial Aneurysm/complications , Intracranial Aneurysm/surgery , Intracranial Hemorrhages/epidemiology , Intracranial Hemorrhages/etiology , Male , Microsurgery , Middle Aged , Neurosurgical Procedures , Treatment Outcome
8.
Rev. neurol. (Ed. impr.) ; 37(2): 112-117, 16 jul., 2003. tab
Article in Es | IBECS | ID: ibc-27849

ABSTRACT

Introducción. Se utiliza la expresión aneurismas intracraneales múltiples (AICM) cuando existen dos o más aneurismas en un mismo paciente. Objetivos. Analizar las características de los AICM y los resultados del tratamiento microneuroquirúrgico. Pacientes y métodos. De un total de 524 pacientes con aneurismas intracraneales (AIC), analizamos 113 con aneurismas múltiples (AM). Los pacientes fueron intervenidos por métodos microneuroquirúrgicos, en uno o dos abordajes, y se evaluaron tres meses después con la escala de pronóstico de Glasgow. Resultados. Hubo un 21,5 por ciento de AM. La edad media fue de 46 años; 85 (75 por ciento) fueron mujeres y 28 (25 por ciento) hombres. Las enfermedades asociadas fueron la hipertensión arterial, la displasia fibromuscular de las carótidas y los aneurismas familiares. Hubo un total de 264 aneurismas: 252 del sistema carotídeo y 12 del sistema vertebrobasilar. El promedio de sacos por paciente fue de 2,3. Encontramos lesiones bilaterales en el 36 por ciento y simétricas o `en espejo' en el 30 por ciento. Las localizaciones más frecuentes fueron: la región de la comunicante posterior y la cerebral anterior-comunicante anterior, bifurcación basilar, región de la arteria oftálmica y arteria cerebral media.Se utilizaron 128 procedimientos quirúrgicos, y en l5 pacientes se realizaron dos. En el 90 por ciento de las lesiones se colocaron grapas; 90 pacientes (79 por ciento) lograron una recuperación completa, 15 (12 por ciento) una incapacidad parcial, tres (4 por ciento) una incapacidad grave y no hubo pacientes en estado vegetativo. Hubo una mortalidad quirúrgica del 4,4 por ciento. Conclusión. Los AICM son lesiones complejas, cada una de las cuales tiene un comportamiento individual, similar a las lesiones únicas del territorio carotídeo o vertebrobasilar. Las técnicas microneuroquirúrgicas ofrecen buenos resultados (AU)


Introduction. It is considered multiple intracranial aneurysms when a patient harbors two or more intracranial aneurysms. Objective. To analyze clinical characteristic and microneurosurgical results of patients with multiple intracranial aneurysms attended in Camagüey. Patients and methods. Between 524 patients operated on to clip aneurysms, we searched 113 patients with multiple intracranial aneurysms. Patients were operated on by microneurosurgical methods and specialized neuroanesthesia. We performed one or two stage operations. Patients were evaluated three month later with Glasgow Outcome scale. Results. There were 21.5% of multiple aneurysms. Age average was 46 years. There were 85 (75%) women and 28 (25%) men. Associated diseases were high blood pressure, carotid fibromuscular dysplasia and familiar aneurysms. There were 264 aneurysms: 252 at the carotid system and 12 at the vertebrobasilar circulation. Sacs average per patients was 2.3. There were 36% of bilateral aneurysms and 30% of symmetric or ‘mirror’ sacs. Nehls algorithm permitted to localize symptomatic lesions at: posterior communicating region, anterior cerebral-anterior communicating artery, basilar bifurcation, ophthalmic region, and middle cerebral artery. We utilized 128 surgical procedures and two stage operations were applied in 15 patients. 90% of aneurysms were clipped. Ninety patients (79%) obtained complete recuperation, 15 (12%) partial incapacity; 3 (4%) severe incapacity and there were not vegetative patients. Five patients died and the mortality rate was 4.4%. Conclusion. Multiple intracranial aneurysms are complex lesions but each one has a similar behavior to sporadic aneurysms. Association to different medical conditions is frequent and microneurosurgery offers good results (AU)


Subject(s)
Middle Aged , Adult , Aged, 80 and over , Aged , Male , Female , Humans , Risk Factors , Vascular Diseases , Vestibular Nuclei , Vestibular Diseases , Comorbidity , Glasgow Coma Scale , Lupus Coagulation Inhibitor , Antibodies, Anticardiolipin , Aneurysm, Ruptured , Neurosurgical Procedures , Antibodies, Antiphospholipid , Treatment Outcome , Microsurgery , Intracranial Hemorrhages , Intracranial Aneurysm , Cuba , Magnetic Resonance Imaging
9.
Neurocirugia (Astur) ; 14(1): 16-24, 2003 Feb.
Article in Spanish | MEDLINE | ID: mdl-12655380

ABSTRACT

INTRODUCTION: Giant intracranial aneurysms represent 2 to 5% of all aneurysms. They are well characterized from the anatomical and clinical point of view. Their natural history shows its potential lethality. Surgical treatment of giant aneurysms is a challenge for neurosurgeons. MATERIAL AND METHODS: Twenty-two patients were operated on through pterional craniotomy, specialized neuroanesthesia and microneurosurgical technics. Auxiliary methods like transitory clipping and retrograde decompression-suction technique were applied. Patients were followed at intensive care units and they were evaluated three months after the operation. Nineteen patients were in the fourth and sixth decade of life. Seventeen were females. Aneurysms were located at middle cerebral artery bifurcation; paraclinoidal carotid artery; proximal anterior cerebral artery and carotid bifurcation. Ninety one percent of aneurysms were clipped. Retrograde decompression-suction technique was performed in thirteen cases. RESULTS: Seventeen patients had good outcome and one patient died (4.5%). There were 6 postoperative complications and in four disappeared three months later. CONCLUSIONS: Giant aneurysms were operated on following main neurosurgical rules helped by auxiliar procedures to reduce aneurysms size and wall, aneurysms tension. New knowledge about giants aneurysms and the development of new techniques will permit better results.


Subject(s)
Intracranial Aneurysm/pathology , Intracranial Aneurysm/surgery , Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Postoperative Complications/epidemiology
10.
Rev Neurol ; 36(3): 218-23, 2003.
Article in Spanish | MEDLINE | ID: mdl-12599150

ABSTRACT

INTRODUCTION: Genetic etiology in suggested in intracranial aneurysms. Such hypothesis is supported on familial aggregation, ocurrence in identical twins or associated to genetic diseases like adult polycystic renal disease. OBJECTIVE: To identify biological features in familial aneurysms different to sporadic ones. PATIENTS AND METHODS: Camag ey province is one of the most ancient in Cuba. Motionless population at the beginning had its sources in Spanish and African people. It has 800,000 inhabitants. 497 patients with intracranial aneurysms were operated at Manuel Ascunce Domenech Hospital between January 1982 and August 2001. We identified 15 families with intracranial aneurysms. RESULTS: 31 patients were operated on of 42 intracranial sacs at the carotid territory. There were 34% of multiplicity ant three mirror aneurysms. Three patients (9.7 %) have adult polycystic renal disease. 87 % of patients present aneurysms rupture and mortality was 32 %. This last figure was related to poor admission clinical grade. CONCLUSIONS: Frequency of familial aneurysms was 6.2% Familial aggregation, aneurysms between twins associated with genetic linked disease, early age rupture, high frequency between women, posterior communicating and middle cerebral artery bifurcation preference, mirror aneurysms and high general mortality associated to massive intracranial bleeding identified this clusters of familial aneurysms and would justify imaginological screening of high risk patients before the rupture.


Subject(s)
Intracranial Aneurysm/epidemiology , Intracranial Aneurysm/genetics , Adolescent , Adult , Cuba/epidemiology , Female , Humans , Intracranial Aneurysm/physiopathology , Intracranial Aneurysm/surgery , Male , Middle Aged , Polycystic Kidney Diseases/physiopathology , Risk Factors , Treatment Outcome
11.
Rev. neurol. (Ed. impr.) ; 36(3): 218-223, 1 feb., 2003. tab
Article in Es | IBECS | ID: ibc-19748

ABSTRACT

Introducción. Se sugiere una posible etiología genética en los aneurismas intracraneales (AIC). Esta hipótesis se apoya en la aparición de varios pacientes en una misma familia, en gemelos idénticos o en personas con enfermedades genéticas asociadas, como la enfermedad renal poliquística del adulto (ERPQA). Objetivo. Identificar las características biológicas de los aneurismas familiares (AF) que lo diferencian de los esporádicos. Pacientes y métodos. La provincia de Camagüey es una de las más antiguas de Cuba. Su población, inmóvil en los inicios, es de origen español y africano.Tiene unos 800.000 habitantes. Un total de 497 pacientes con AIC fueron operados en el quirófano del Hospital Manuel Ascunce Doménech en el período de enero de 1982 a agosto de 2001. Se identificaron en ellos 15 familias con pacientes con AIC. Resultados. Se intervinieron quirúrgicamente 31 pacientes de 15 familias, los cuales tenían 42 aneurismas del territorio carotídeo. Hubo un 34 por ciento de multiplicidad, y en tres pacientes las lesiones eran en `espejo'. Tres pacientes (9,7 por ciento) tenían ERPQA. El 87 por ciento de los aneurismas se manifestaron como hemorragias intracraneales. La mortalidad fue del 32 por ciento debido al pobre estado clínico de los pacientes al ingreso. Conclusiones. La frecuencia de AF fue del 6,2 por ciento. La agrupación familiar, la aparición en hermanos gemelos, la asociación a enfermedades genéticas, la tendencia a la ruptura en edades tempranas, la mayor frecuencia en mujeres, la localización predominante en la región de la comunicación posterior y la bifurcación de la arteria cerebral media o en sacos en `espejo' y la elevada mortalidad, caracterizan a este grupo de aneurismas. Esto justifica el estudio de familiares con riesgo elevado antes de que ocurra el sangrado (AU)


Introduction. Genetic etiology in suggested in intracranial aneurysms. Such hypothesis is supported on familial aggregation, ocurrence in identical twins or associated to genetic diseases like adult polycystic renal disease. Objective. To identify biological features in familial aneurysms different to sporadic ones. Patients and methods. Camagüey province is one of the most ancient in Cuba. Motionless population at the beginning had its sources in Spanish and African people. It has 800,000 inhabitants. 497 patients with intracranial aneurysms were operated at Manuel Ascunce Domenech Hospital between January 1982 and August 2001. We identified 15 families with intracranial aneurysms. Results. 31 patients were operated on of 42 intracranial sacs at the carotid territory. There were 34% of multiplicity ant three ‘mirror’ aneurysms. Three patients (9.7 %) have adult polycystic renal disease. 87 % of patients present aneurysms rupture and mortality was 32 %. This last figure was related to poor admission clinical grade. Conclusions. Frequency of familial aneurysms was 6.2% Familial aggregation, aneurysms between twins associated with genetic linked disease, early age rupture, high frequency between women, posterior communicating and middle cerebral artery bifurcation preference, ‘mirror’ aneurysms and high general mortality associated to massive intracranial bleeding identified this clusters of familial aneurysms and would justify imaginological screening of high risk patients before the rupture (AU)


Subject(s)
Middle Aged , Adolescent , Adult , Male , Female , Humans , Risk Factors , Treatment Outcome , Intracranial Aneurysm , Cuba , Polycystic Kidney Diseases
12.
Neurocir. - Soc. Luso-Esp. Neurocir ; 14(1): 16-24, feb. 2003.
Article in Es | IBECS | ID: ibc-20327

ABSTRACT

Introducción. Los aneurismas intracraneales supra-tentoriales gigantes (AISG) representan del 2 al 5 por ciento de todos los aneurismas. Ellos están bien caracterizados desde el punto de vista clínico y en los estudios de imagen. Su presentación clínica demuestra su potencial letalidad. El tratamiento quirúrgico de estas lesiones constituye un reto para el neurocirujano. Material y métodos. Un total de 22 pacientes con aneurismas supratentoriales gigantes fueron sometidos a craneotomía pterional, neuroanestesia especializada y técnicas microneuroquirúrgicas. Se aplicaron métodos auxiliares como el clipaje transitorio o la técnica de descompresión-succión retrógrada en los sacos paraclinoideos. El postoperatorio se desarrolló en Terapia Intensiva y los pacientes fueron evaluados a los 3 meses de operados. Diecinueve pacientes estaban entre la cuarta y la sexta década de la vida y 17 eran del sexo femenino. Las lesiones se ubicaban en la bifur-cación de la arteria cerebral media, región carotídea paraclinoidea, cerebral anterior proximal y bifurcación carotídea. El clipaje se logró en el 91 por ciento de las lesiones. En 13 pacientes se realizó la técnica de descompresión-succión retrógrada. Resultados. En 17 (77 por ciento) pacientes hubo recuperación completa y un enfermo falleció (4.5 por ciento). Las complicaciones postoperatorias fueron seis; pero cuatro se resolvieron antes de los tres meses. Conclusiones. Los aneurismas gigantes supratentoriales pueden ser tratados siguiendo los principios básicos del manejo neuroquirúrgico de los aneurismas y con procederes auxiliares que disminuyan el tamaño y la tensión en la pared de los sacos, para poder lograr el clipaje. El mayor conocimiento sobre estas lesiones y el desarrollo de nuevas técnicas permitirá obtener mejores resultados (AU)


Subject(s)
Middle Aged , Adolescent , Adult , Aged , Male , Female , Humans , Postoperative Complications , Intracranial Aneurysm
13.
Neurocirugia (Astur) ; 13(5): 371-7, 2002 Oct.
Article in Spanish | MEDLINE | ID: mdl-12444408

ABSTRACT

Elderly patients are a growing population group in developing countries because of optimal health care. 13% of Cuba population is older than sixty years and it is expected to grow to 20% in 2005. Subarachnoid hemorrhage secondary to ruptured aneurysms in geriatric patients carries a high mortality but a few patients are selected for surgical treatment. Manuel Ascunce Domenech Hospital attended 1112 patients older than 60 years between January 1994 and December 2001. Of these there were 96 patients with symptomatic intracranial aneurysms and we selected 30 for surgical treatment. They were all in clinical grades I and II of the WFNS scale. They had good health to face surgery and familiar consent. The size and location of the aneurysms were not considered among the exclusion criteria. Aneurysms were mainly localized at posterior communicating and middle cerebral arteries. There were two deaths, one due to a medical cause an the other to the surgical procedure. 74% of the patients obtained satisfactory outcome six month after the operation. The clue is to not consider age as a negative point for surgery. Surgical procedures can be performed in patients with good clinical grade (WFNS). New technical advances, stroke units, accurately selected patients and minimal invasive surgical methods will help to obtain good results.


Subject(s)
Intracranial Aneurysm/surgery , Neurosurgical Procedures/methods , Age Factors , Aged , Aged, 80 and over , Female , Humans , Intracranial Aneurysm/complications , Male , Middle Aged , Severity of Illness Index , Subarachnoid Hemorrhage/etiology , Subarachnoid Hemorrhage/surgery
14.
Rev Neurol ; 35(6): 512-6, 2002.
Article in Spanish | MEDLINE | ID: mdl-12389165

ABSTRACT

INTRODUCTION AND OBJECTIVE: Hemangioblastomas of the central nervous system are the most frequent vascular tumours. They are 1 2% of primary nervous system tumours and 8 12% of the posterior fossa neoplasms. The objective is to analize clinical behaviour and long term results of sporadic and Von Hippel Lindau linked hemangioblastomas. PATIENTS AND METHODS: It was searched the vacular Neurosurgical Data Bank at Manuel Ascunce Dom nech Hospital between January 1981 and January 2001 to select patients harvoring central nervous system hemangioblastomas histological confirmed. Melmo and Rosen criteria were utilized in Von Hippel Lindau syndrome. We performed a twenty years follow up of this patients. RESULTS: There were 12 patients with central nervous system hemangioblastomas. Average age of presentation was 41 years old. The first case had twenty years since the operation and the last, eight months. 83% were cystic and 17% were solids. There was not surgical mortality. One patient died of renal carcinoma 15 years after the operation on craneal fossa. CONCLUSION: Central nervous system hemangioblastomas are a cluster of challenge tumours. They are intraxial benign tumours with potential good outcome. We observed sporadic and Von Hippel Lindau linked hemangioblastomas. Patients with this syndrome need clinico imagenological screening to identify new associated lesions.


Subject(s)
Central Nervous System Neoplasms/epidemiology , Hemangioblastoma/epidemiology , von Hippel-Lindau Disease/epidemiology , Adult , Cuba/epidemiology , Female , Humans , Male , Middle Aged
15.
Rev. neurol. (Ed. impr.) ; 35(6): 512-516, 16 sept., 2002.
Article in Es | IBECS | ID: ibc-22213

ABSTRACT

Introducción y objetivos. Los hemangioblastomas del sistema nervioso central son la neoplasia de origen vascular más frecuente. Constituyen del 1 al 2 por ciento de todas las neoplasias primarias del sistema nervioso y del 8 al 12 por ciento de los tumores de la fosa posterior. El objetivo de este trabajo es analizar el comportamiento de los hemangioblastomas esporádicos ligados a la enfermedad de Von Hippel-Lindau y los resultados a largo plazo. Pacientes y métodos. Se seleccionaron los pacientes con hemangioblastomas confirmados mediante un estudio histológico. En los pacientes con síndrome de Von Hippel-Lindau se utilizaron los criterios de Melmo y Rosen. A todos los pacientes se les intervino con métodos microneuroquirúrgicos y magnificación óptica. Se realizó un seguimiento de todos estos casos en los últimos 20 años. Resultados. Hubo 12 pacientes con hemangioblastomas. La edad promedio de presentación fue de 41 años. El primer paciente fue intervenido hace 20 años, y el último, ocho meses. El 83 por ciento eran lesiones únicas, y el 17 por ciento, múltiples ligadas al síndrome de Von Hippel-Lindau. La localización más frecuente fue el cerebelo. No se produjo ninguna mortalidad quirúrgica, si bien un paciente falleció por carcinoma renal 15 años después de la intervención de fosa craneal. Conclusión. Los hemangioblastomas del sistema nervioso constituyen un subgrupo de tumores vasculares que son un reto, además de lesiones benignas esporádicas y asociadas al síndrome de Von Hippel-Lindau. Este último subgrupo requiere de seguimiento clínico imaginológico periódico para identificar nuevas lesiones asociadas (AU)


Subject(s)
Middle Aged , Adult , Male , Female , Humans , Hemangioblastoma , Cuba , von Hippel-Lindau Disease , Central Nervous System Neoplasms
16.
Article in Es | IBECS | ID: ibc-26301

ABSTRACT

Las personas mayores de 60 años representan un grupo poblacional que crece en países desarrollados con servicios de salud óptimos. Este grupo representa en Cuba el 13 por ciento del total y se espera que alcance el 20 por ciento para el 2005. La hemorragia subaracnoidea por aneurisma intracraneal en pacientes ancianos tiene una elevada mortalidad; pero pocos son los seleccionados para cirugía. El hospital Manuel Ascunce Doménech de Camagüey, Cuba atendió 1112 pacientes mayores de 60 años en el periodo de enero de 1994 a febrero del 2001. Dentro de ellos 96, el 8,6 por ciento ingresaron por aneurismas intracraneales sintomáticos y fueron seleccionados para cirugía 30, el 31,3 por ciento Se utilizaron como criterios de inclusión los pacientes con un estado clínico grado I o grado 11 de la Federación Mundial de Neurocirujanos, la existencia de enfermedades intercurrentes controladas o cuando la familia y el paciente lo autorizaron. Se utilizaron métodos microneuroquirúrgicos, magnificación óptica y soporte craneal de Sugita. Fueron intervenidos entre el cuarto y el décimo día. Los pacientes fueron atendidos en el postoperatorio en la sala de terapia intensiva. Las localizaciones más frecuentes fueron la comunicante posterior y la bifurcación de la arteria cerebral media. Hubo 22 aneurismas pequeños y 10 grandes. No hubo gigantes. Hubo dos fallecidos (-6 por ciento) uno por causa médica y otro quirúrgica. El 74 por ciento obtuvo recuperación clínica completa, seis meses después de la intervención. La edad no es un elemento que contraindique la cirugía. El tratamiento quirúrgico de los aneurismas intracraneales puede realizarse en pacientes con buen estado clínico, posibilidad de actividad independiente después de la cirugía y con buen estado de salud para enfrentar la operación. Nuevos avances científico-técnicos, las unidades de ictus, una mejor selección de los casos y métodos quirúrgicos mínimamente invasivos ayudarán a obtener mejores resultados. (AU)


Subject(s)
Middle Aged , Aged , Aged, 80 and over , Male , Female , Humans , Subarachnoid Hemorrhage , Neurosurgical Procedures , Intracranial Aneurysm , Age Factors , Severity of Illness Index
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