[Velo-cardio-facial syndrome at the psychiatry consulting-liaison service in a general hospital]. / El síndrome velocardiofacial en la interconsulta psiquiátrica en un hospital general.

Psychotic syndromes secondary to genomic disorders have low prevalence and may easily go unnoticed in the daily clinical practice. The velo-cardio-facial syndrome or DiGeorge syndrome (VCFS/DGS) is the genomic disorder most frequently associated to an interstitial deletion of the 22q11 region, with an incidence of one per every 4,000 newborns. Clinical manifestations constitute a constellation of cardiac, facial, urogenital and psychiatric disorders, among which schizophrenia or schizophreniform disorder stand out with an incidence of about 30% over the lifetime. In the following, we present the case of a 21 year old female patient who was admitted to the hematology service of our hospital due to pancytopenia secondary to metimazole, who had non-specified psychiatric background and who received antipsychotic treatment.

El síndrome velocardiofacial en la interconsulta psiquiátrica en un hospital general / Velo-Cardio-Facial syndrome at the psychiatry consulting-liaison service in a general hospital

Los síndromes psicóticos secundarios a alteraciones genómicas tienen una baja prevalencia y pueden pasar fácilmente inadvertidos en la práctica clínica diaria. El síndrome velocardiofacial o síndrome de DiGeorge (SVCF/SDG) es el trastorno genómico más frecuentemente asociado a una deleción intersticial de la región 22q11, con una incidencia de 1 por cada 4.000 recién nacidos. Las manifestaciones clínicas constituyen una pléyade de alteraciones cardíacas, faciales, urogenitales y psiquiátricas, entre las que destaca la esquizofrenia o el trastorno esquizofreniforme con una incidencia de cerca del 30 % a lo largo de la vida. A continuación presentamos el caso de una paciente de 21 años de edad que ingresó en el servicio de hematología de nuestro hospital por una pancitopenia secundaria a metimazol y que presentaba antecedentes psiquiátricos no bien filiados y realizaba tratamiento antipsicótico

Psychotic syndromes secondary to genomic disorders have low prevalence and may easily go unnoticed in the daily clinical practice. The velo-cardio-facial syndrome or DiGeorge syndrome (VCFS/DGS) is the genomic disorder most frequently associated to an interstitial deletion of the 22q11 region, with an incidence of one per every 4,000 newborns. Clinical manifestations constitute a constellation of cardiac, facial, urogenital and psychiatric disorders, among which schizophrenia or schizophreniform disorder stand out with an incidence of about 30 % over the lifetime. In the following, we present the case of a 21 year old female patient who was admitted to the hematology service of our hospital due to pancytopenia secondary to metimazole, who had non-specified psychiatric background and who received antipsychotic treatment