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2.
Arch Mal Coeur Vaiss ; 100(8): 649-53, 2007 Aug.
Article in French | MEDLINE | ID: mdl-17928769

ABSTRACT

OBJECTIVE: To study the metabolic syndrome (MS) components in Caribbean non diabetic individuals and to determine the magnitude of hypertension (HT) in those with and without MS. RESEARCH METHODS: We conducted a cross-sectional study, of 966 consecutive subjects aged 18-74 years. The MS was identified according to the NCEP/ATpiiI definition. Age, gender, body mass index and the MS components (blood pressure, waist circumference, fasting blood glucose, triglycerides, HDL cholesterol) were taken into account. The Principal component analysis (PCA) was used to understand correlations between these continuous variables within the data base, and to identify principal factors (combinations of variables) and the magnitude of HT in these combinations. RESULTS: In the overall study population, mean age was 38 years and there were 60.1% of women. HT was more frequently found in men than in women (52.2% vs. 41.3%; p=0.001). Prevalence of MS was 11.3%. With PCA, in the complete sample of men, the first factor, explained 31.5% of the total variance in the original variables and was dominated by blood pressure, clustered with age and fasting blood glucose (FBG). In the women's sample, the first factor (31.1% of the variance) was dominated by obesity combined with FBG and lipids. In subjects with the metabolic syndrome the principal factors were dominated by blood pressure in both genders with higher loadings in men than in women. CONCLUSION: In this non diabetic population study the prevailing obese women profile clustering with fasting glucose and lipid disturbances might explain the higher prevalence of type 2 diabetes among women, observed in this Caribbean region.


Subject(s)
Hypertension/epidemiology , Metabolic Syndrome/epidemiology , Adolescent , Adult , Age Factors , Aged , Cross-Sectional Studies , Female , Guadeloupe/epidemiology , Humans , Male , Middle Aged , Obesity/epidemiology , Prevalence , Principal Component Analysis , Sex Factors
3.
Methods Inf Med ; 40(1): 12-7, 2001 Mar.
Article in English | MEDLINE | ID: mdl-11310154

ABSTRACT

Mutual information between a survival variable and covariables provides a new tool for selecting covariables with a high predictive value whenever there is no reasonable parametric model with respect to the observed phenomena. The information rate carried out by covariables can be tested by means of a decomposition similar to the analysis of variance. Moreover, a method based on information conservation can be used for aggregating survival curves corresponding to different modalities of the same selected predictor which increases the prediction efficiency. These results are applied to survival data from 1304 patients with breast cancer followed over a period of ten years.


Subject(s)
Breast Neoplasms/diagnosis , Information Theory , Models, Statistical , Breast Neoplasms/mortality , Entropy , Female , Humans , Prognosis , Statistics, Nonparametric , Survival Analysis
4.
ABCD (São Paulo, Impr.) ; 5(1): 8-11, jan.-fev. 1990. tab
Article in English | LILACS | ID: lil-106022

ABSTRACT

Estudo multicentrico, prospectivo, efetuado por cirurgioes de seis diferentes hospitais de Paris. Os criterios de selecao foram: doenca litiasica sintomatica, vesicula funcionante e presenca de um a cinco calculos de diametro superior a 30 mm. O aparelho utilizado foi o "French Sonolith 3000" e foi respeitado o limite de 2500 choques por sessao. Foram realizadas mais de quatro sessoes. Foram analisados 153 pacientes. Depois das sessoes, 31 tiveram dor no quadrante superior direito do abdome, dois colica biliar, dois febre e tres hematuria transitoria. Apos a ultima sessao, 26 por cento dos doentes nao tinham calculos residuais ou fragmentos de menos de 2 mm (bons resultados), 39 por cento apresentaram fragmentos de mais de 5 mm e 20 por cento nao haviam tido fragmentacao dos calculos. Bons resultados foram observados em: 1) 27 por cento dos calculos radiolucentos e 24 por cento dos calcificados; 2) 33 por cento dos casos de calculo unico, 13 porcento dos de dois calculos e 21 por cento dos de tres a cinco calculos; 3) 29 por cento dos doentes de calculos de menos de 10 mm, 27 por cento dos que tinham calculos de 10 a 20 mm e 18 por cento naqueles cujo diametro era de 20 a 30 mm. Dois enfermos necessitaram de esfincterotomia endoscopica logo depois de litotripsia para retirada de fragmentos coledocianos;...


Subject(s)
Lithotripsy , Cholelithiasis/therapy , Lithotripsy/adverse effects , Cholecystectomy , Cholecystography , Gallstones
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