Assuntos
Dietilcarbamazina/efeitos adversos , Encefalite/induzido quimicamente , Infecções Oculares Parasitárias/tratamento farmacológico , Filaricidas/efeitos adversos , Loíase/tratamento farmacológico , Adulto , Encefalite/diagnóstico por imagem , Eosinofilia/parasitologia , Infecções Oculares Parasitárias/diagnóstico , Feminino , Humanos , Loíase/diagnóstico , ViagemAssuntos
Pan-Uveíte/patologia , Vasculite Retiniana/patologia , Tuberculose Ocular/patologia , Adulto , Diagnóstico Diferencial , Hemianopsia/microbiologia , Hemianopsia/patologia , Humanos , Isquemia/microbiologia , Isquemia/patologia , Masculino , Pan-Uveíte/microbiologia , Vasculite Retiniana/microbiologia , Tuberculose Ocular/complicaçõesRESUMO
Ocular syphilis is a resurgent clinical condition due to unsafe sexual practices. It has been reported in both immunocompromised and immunocompetent patients, but in HIV positive patients, it is more likely to exhibit a more aggressive course and adopt atypical clinical patterns such as optic nerve involvement. Herein we report an atypical case of optic neuritis secondary to syphilis in an HIV negative patient. This case highlights the importance of considering syphilis in the differential diagnosis of ocular inflammation and of obtaining HIV serology, since both diseases share common risk factors.
Assuntos
Infecções Oculares Bacterianas/patologia , Doenças do Nervo Óptico/microbiologia , Sífilis/complicações , Soronegatividade para HIV , Humanos , Masculino , Pessoa de Meia-Idade , Doenças do Nervo Óptico/patologia , Sífilis/patologiaRESUMO
CASO CLÍNICO: Mujer de 24 años con rash maculopapular, aftas orales y genitales, dolor abdominal, disnea leve y disminución de la agudeza visual en ambos ojos. La funduscopia reveló una vasculitis oclusiva bilateral que incluía los vasos centrales. Se inició tratamiento con bolos de metilprednisolona (1 g/24 h) e infliximab 5 mg/kg/día (0-2-6 semanas y cada 8 semanas). El tratamiento indujo una rápida remisión. La agudeza visual mejoró. Tras un año de seguimiento no ha presentado ningún nuevo brote. DISCUSIÓN: Un tratamiento de inicio con infliximab debe considerarse en brotes graves de enfermedad de Behçet como una vasculitis oclusiva bilateral con isquemia
CASE REPORT: A 24 year old woman who complained of maculo-papulo rash, genital and bucal aphthous ulcers, abdominal pain, minor dyspnea and visual loss in both eyes. Funduscopy revealed a bilateral occlusive vasculitis including central vessels. Treatment was initiated with a methylprednisolone bolus (1 g/24 h) and infliximab 5 mg/kg/day (0-2-6 weeks and every 8 weeks). The treatment prescribed induced a fast remission. Visual acuity improved. The patient did not suffer any other relapse after one year of follow-up. DISCUSSION: An initial treatment with Infliximab should be considered in Behçet disease for serious outbreaks, such as macular occlusive vasculitis with ischemia
Assuntos
Feminino , Humanos , Vasculite/congênito , Vasculite/metabolismo , Estomatite Aftosa/complicações , Estomatite Aftosa/enfermagem , Dispneia/complicações , Dispneia/fisiopatologia , Acuidade Visual/genética , Vasculite/complicações , Vasculite/fisiopatologia , Estomatite Aftosa/metabolismo , Estomatite Aftosa/patologia , Dispneia/diagnóstico , Dispneia/enfermagem , Acuidade Visual/fisiologiaAssuntos
Cegueira/história , Educação de Pessoas com Deficiência Visual/história , Leitura , Auxiliares Sensoriais/história , Acidentes de Trabalho , Cegueira/etiologia , Educação de Pessoas com Deficiência Visual/métodos , Traumatismos Oculares/complicações , Docentes , História do Século XIX , Humanos , Masculino , Oftalmia Simpática/etiologia , Paris , Ensino/históriaRESUMO
No disponible
Assuntos
Humanos , Masculino , Feminino , Criança , Oftalmologia/classificação , Hamartoma/complicações , Hamartoma/diagnóstico , Esclerose Tuberosa/diagnóstico , Esclerose Tuberosa/genética , Esclerose Tuberosa/metabolismo , Neurofibromatose 1/complicações , Neurofibromatose 1/metabolismo , Tomografia , Oftalmologia/instrumentação , Hamartoma/genética , Hamartoma/prevenção & controle , Esclerose Tuberosa/complicações , Neurofibromatose 1 , Tomografia/instrumentaçãoRESUMO
CASE REPORT: A 24 year old woman who complained of maculo-papulo rash, genital and bucal aphthous ulcers, abdominal pain, minor dyspnea and visual loss in both eyes. Funduscopy revealed a bilateral occlusive vasculitis including central vessels. Treatment was initiated with a methylprednisolone bolus (1 g/24h) and infliximab 5mg/kg/day (0-2-6 weeks and every 8 weeks). The treatment prescribed induced a fast remission. Visual acuity improved. The patient did not suffer any other relapse after one year of follow-up. DISCUSSION: An initial treatment with Infliximab should be considered in Behçet disease for serious outbreaks, such as macular occlusive vasculitis with ischemia.
Assuntos
Síndrome de Behçet/diagnóstico , Imunossupressores/uso terapêutico , Infliximab/uso terapêutico , Metilprednisolona/uso terapêutico , Vasculite/tratamento farmacológico , Síndrome de Behçet/complicações , Feminino , Angiofluoresceinografia , Humanos , Oftalmoscopia , Indução de Remissão , Tomografia de Coerência Óptica , Vasculite/diagnóstico por imagem , Vasculite/etiologia , Adulto JovemRESUMO
OBJETIVO: Comparar los valores de presión intraocular (PIO) del nuevo tonómetro de no contacto Corvis ST (CST) con la tonometría de aplanación de Goldmann (GAT) y la tonometría de rebote Icare Pro (PRO). MATERIAL Y MÉTODOS: Se seleccionaron 178 ojos de 178 voluntarios sanos a los que se les midió la PIO de manera aleatorizada con CST, PRO y GAT. Se midió el espesor corneal central (GCC) con paquimetría ultrasónica. Para cada variable, se tomaron 3 medidas y la media de las 3 fue introducida en el análisis estadístico. La concordancia entre los tonómetros se determinó mediante las gráficas de Bland-Altmann. RESULTADOS: La PIO medias obtenidas con los 3 tonómetros fueron de 15,5 ± 2,8 mmHg para GAT, 14,6 ± 2,3 mmHg para PRO y 15,4 ± 2,8 mmHg para CST. La diferencia media entre pares de tonómetros fue: GAT-PRO = 0,9 ± 1,7 mmHg (p < 0,001); GAT-CST: 0,1 ± 2,2 (p = 0,398) y PRO-CST: −0,8 ± −0,7 mmHg, p < 0,001. En los 3 casos se encontró una correlación significativa con el GCC: GAT: r = 0,325, p < 0,001; PRO: r = 0,385, p < 0,001 y CST: r = 0,428; p < 0,001. CONCLUSIONES: Las diferencias encontradas entre el PRO y el GAT son significativamente mayores que entre el CST y el GAT, sin diferencias significativas entre las medidas de estos 2. Las medidas de los 3 tonómetros se ven afectadas por el GCC
PURPOSE: To compare intraocular pressure (IOP) between the new non-contact tonometer Corvis ST (CST), the Goldmann applanation tonometry (GAT) and Icare Pro rebound tonometer (PRO). METHODS: A total of 178 eyes of 178 healthy subjects were selected for the study. Measurements of IOP were made in a random order with GAT, PRO and CST. Central corneal thickness (CCT) was determined by ultrasound pachymetry. The mean of three valid measurements of each variable was used in the statistical analysis. The relationship between the tonometers was established using Bland-Altman plots. RESULTS: Mean IOP was 15.5±2.8 mmHg for GAT, 15.4±2.8 mmHg for CST, and 14.6±2.3 mmHg for PRO. The mean differences between pairs of tonometers were: GATPRO= 0.9±1.7 mmHg (P<0.001), GAT-CST: 0.1±2.2 (P=0.398), and PRO-CST: −0.8±−0.7 mmHg,p < 0.001. A positive relationship was detected between CCT and the three tonometers: GAT:r = 0.325, P<0.001; PRO: r = 0.385, P<0.001, and CST: r = 0.428; P<0.001. CONCLUSIONS: The differences found between PRO and GAT were significantly higher than those found between CST and GAT, which showed non-significant differences. The measurements of the three tonometers were affected by the CCT
Assuntos
Humanos , Tonometria Ocular/métodos , Pressão Intraocular , Determinação da Pressão Arterial/métodos , Reprodutibilidade dos TestesRESUMO
PURPOSE: To compare intraocular pressure (IOP) between the new non-contact tonometer Corvis ST (CST), the Goldmann applanation tonometry (GAT) and Icare Pro rebound tonometer (PRO). METHODS: A total of 178 eyes of 178 healthy subjects were selected for the study. Measurements of IOP were made in a random order with GAT, PRO and CST. Central corneal thickness (CCT) was determined by ultrasound pachymetry. The mean of three valid measurements of each variable was used in the statistical analysis. The relationship between the tonometers was established using Bland-Altman plots. RESULTS: Mean IOP was 15.5 ± 2.8 mmHg for GAT, 15.4 ± 2.8 mmHg for CST, and 14.6 ± 2.3 mmHg for PRO. The mean differences between pairs of tonometers were: GAT-PRO=0.9 ± 1.7 mmHg (P<.001), GAT-CST: 0.1 ± 2.2 (P=.398), and PRO-CST: -0.8 ±-0.7 mmHg, p<0.001. A positive relationship was detected between CCT and the three tonometers: GAT: r=0.325, P<.001; PRO: r = 0.385, P<.001, and CST: r = 0.428; P<.001. CONCLUSIONS: The differences found between PRO and GAT were significantly higher than those found between CST and GAT, which showed non-significant differences. The measurements of the three tonometers were affected by the CCT.