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1.
Acta ortop. mex ; 33(5): 289-291, sep.-oct. 2019. tab
Artigo em Espanhol | LILACS | ID: biblio-1284958

RESUMO

Resumen: Introducción: Las alteraciones de la huella plantar en el niño es causa de preocupación en los padres de familia. Objetivo: Determinar la frecuencia de alteraciones de la huella plantar en escolares. Determinar si existe relación entre el sobrepeso y la obesidad con la presencia de alteraciones de la huella plantar. Material y métodos: Estudio observacional, transversal y prospectivo. Se evaluaron 959 escolares de seis a 13 años de edad. Se registró peso, talla, índice de masa corporal para la edad. La huella plantar se catalogó en pie plano y pie cavo utilizando el índice del arco. Para el análisis y comparación estadística se utilizó el programa SPSS versión 24 con las pruebas χ2 y ANOVA. Resultados: Se revisaron 530 niños (55.3%) y 429 niñas (44.7%). La media de edad fue de 8.97 años. Se observaron 182 niños (19%) con alteración de la huella plantar, 42.3% con pie plano y 57.7% con pie cavo. Ninguno mostró sintomatología del pie. Ciento treinta y un niños tenían sobrepeso y 52 obesidad, sin influir en la presencia de alguna alteración de la huella plantar (p = 0.20). La relación de pie plano fue mayor en los hombres (2.5:1) y de pie cavo fue mayor en las mujeres (1.3:1). Conclusiones: En nuestro grupo de estudio se encontró mayor prevalencia del pie cavo en comparación con el pie plano. El peso corporal no influyó en las alteraciones de la huella plantar.


Abstract: Introduction: Alterations in the plantar footprint in the child are a cause for concern in parents. Objective: Determine the frequency of plantar footprint alterations in school children. Determine if there is a relationship between overweight and obesity with the presence of alterations of the plantar footprint. Material and methods: Observational, transversal and prospective study. 959 schoolchildren aged six to 13 were evaluated. Weight, size, body mass index for age were recorded. The plantar footprint was cataloged on flat foot and cavus foot using the arch index. For statistical analysis and comparison, the SPSS version 24 program was used with the χ2 and ANOVA tests. Results: 530 children (55.3%) and 429 girls (44.7%). The median age was 8.97 years. 182 children were found (19%) with alteration of the plantar footprint, 42.3% with flat foot and 57.7% with cavus foot. None of them had foot symptoms. 131 children were overweight and 52 obese, without influencing the presence of any alteration of the plantar footprint (p = 0.20). The flat-foot ratio was higher in men (2.5:1) and standing cavus major in women (1.3:1). Conclusions: In our study group we find a higher prevalence of the cavus foot compared to the flat foot. Body weight did not influence plantar footprint alterations.


Assuntos
Humanos , Masculino , Feminino , Criança , Peso Corporal , Pé Chato , Índice de Massa Corporal , Estudos Prospectivos , , México
2.
Cell Tissue Res ; 375(2): 507-529, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30259139

RESUMO

The subcommissural organ (SCO) is an ancient and conserved brain gland secreting into cerebrospinal fluid (CSF) glycoproteins that form the Reissner fiber (RF). The present investigation was designed to further investigate the dynamic of the biosynthetic process of RF glycoproteins prior and after their release into the CSF, to identify the RF proteome and N-glycome and to clarify the mechanism of assembly of RF glycoproteins. Various methodological approaches were used: biosynthetic labelling injecting 35S-cysteine and 3H-galactose into the CSF, injection of antibodies against galectin-1 into the cerebrospinal fluid, light and electron microscopical methods; isolated bovine RF was used for proteome analyses by mass spectrometry and glycome analysis by xCGE-LIF. The biosynthetic labelling study further supported that a small pool of SCO-spondin molecules rapidly enter the secretory pathways after its synthesis, while most of the SCO-spondin molecules are stored in the rough endoplasmic reticulum for hours or days before entering the secretory pathway and being released to assemble into RF. The proteomic analysis of RF revealed clusterin and galectin-1 as partners of SCO-spondin; the in vivo use of anti-galectin-1 showed that this lectin is essential for the assembly of RF. Galectin-1 is not secreted by the SCO but evidence was obtained that it would be secreted by multiciliated ependymal cells lying close to the SCO. Further, a surprising variety and complexity of glycan structures were identified in the RF N-glycome that further expands the potential functions of RF to a level not previously envisaged. A model of the macromolecular organization of Reissner fiber is proposed.


Assuntos
Glicoproteínas/metabolismo , Órgão Subcomissural/fisiologia , Animais , Bovinos , Cisteína/metabolismo , Citoplasma/metabolismo , Epêndima/citologia , Epêndima/metabolismo , Galactose/metabolismo , Galectina 1/metabolismo , Glicoproteínas/ultraestrutura , Glicosilação , Masculino , Polissacarídeos/química , Polissacarídeos/metabolismo , Ratos Sprague-Dawley , Via Secretória , Coloração e Rotulagem , Órgão Subcomissural/ultraestrutura , Radioisótopos de Enxofre/metabolismo , Trítio/metabolismo
3.
Acta odontol. venez ; 51(1)2013. tab
Artigo em Espanhol | LILACS | ID: lil-684724

RESUMO

La caries dental es una enfermedad crónica, infecciosa, transmisible y de etiología multifactorial que produce un efecto destructivo sobre el diente. Comparar la presencia de caries en primeros molares permanentes de los niños VIH (+) y VIH (-) todos hijos de madres VIH (+) que acudieron a el Centro de Atención a Pacientes con Enfermedades Infectocontagiosas de Facultad de Odontología de Universidad Central de Venezuela (CAPEI). Revisión retrospectiva durante el año 2006 de 52 historias clínicas de los niños que presentaban en boca el primer molar permanente de 26 niños VIH (+) y 26 niños VIH (-) hijos de madres VIH (+); durante el periodo 2006 la metodología estadística empleada fue la prueba de Pearson. Al comparar la presencia de caries en los niños VIH (+) se encontró un 57,6% de dientes afectados mientras que solo el 11,5% se observó en los VIH (-), al aplicar la prueba de Pearson arrojo un valor p=0,01 y or= 7.3* lo que representa un alta significancia estadística. Queda bien establecida la importancia del odontopediatra dentro del equipo interdisciplinario que maneja al niño VIH (+), sobre quien recaerá la responsabilidad de controlar los factores predisponentes de la caries extremando las medidas preventivas y educativas odontológicas y factores locales sistémicos consecuencia de la infección


Dental caries is a disease chronic, infectious and multifactorial etiology that produces a destructive effect on the tooth. Compare the presence of caries in permanent molars first HIV children and HIV (+) all children of mothers HIV (-) attended the service to patients with diseases Infectocontagiosas faculty dentistry Venezuela Central University Centre. review retrospective 52 records in children presented in mouth's first molar permanent 26 children HIV (+) and 26 children HIV (-) children of mothers HIV (+); the period 2006 la statistical methodology was proof of Pearson. when comparing the presence of caries in children HIV (+) found affected teeth 57,6 % while that only 11.5 % I note in the HIV (-), when you apply the Pearson test weeding a value p = 0, 01 and or = 7.3 * what represents a high statistical significance. Is well established the importance of the pediatric dentist in the interdisciplinary team that handles the HIV children, on who will bear responsibility for control of decay, predisposing factors, dental preventive and educational measures and systemic local factors result of the infection


Assuntos
Humanos , Masculino , Feminino , Criança , Cárie Dentária/imunologia , Dente Molar/imunologia , HIV , Soronegatividade para HIV , Soropositividade para HIV , Prevalência , Odontologia
4.
Acta odontol. venez ; 51(1)2013. tab
Artigo em Espanhol | LILACS | ID: lil-684725

RESUMO

La caries dental es una enfermedad crónica, infecciosa, transmisible y de etiología multifactorial que produce un efecto destructivo sobre el diente. Objetivo: Comparar la presencia de caries en primeros molares permanentes de los niños VIH (+) y VIH (-) todos hijos de madres VIH (+) que acudieron a el Centro de Atención a Pacientes con Enfermedades Infectocontagiosas de Facultad de Odontología de Universidad Central de Venezuela (CAPEI). Materiales y Métodos: Revisión retrospectiva durante el año 2006 de 52 historias clínicas de los niños que presentaban en boca el primer molar permanente de 26 niños VIH (+) y 26 niños VIH (-) hijos de madres VIH (+); durante el periodo 2006 la metodología estadística empleada fue la prueba de Pearson. Resultados: Al comparar la presencia de caries en los niños VIH (+) se encontró un 57,6% de dientes afectados mientras que solo el 11,5% se observó en los VIH (-), al aplicar la prueba de Pearson arrojo un valor p=0,01 y or= 7.3* lo que representa un alta significancia estadística. Conclusión: Queda bien establecida la importancia del odontopediatra dentro del equipo interdisciplinario que maneja al niño VIH (+), sobre quien recaerá la responsabilidad de controlar los factores predisponentes de la caries extremando las medidas preventivas y educativas odontológicas y factores locales sistémicos consecuencia de la infección


Dental caries is a disease chronic, infectious and multifactorial etiology that produces a destructive effect on the tooth. Objective: Compare the presence of caries in permanent molars first HIV children and HIV (+) all children of mothers HIV (-) attended the service to patients with diseases Infectocontagiosas faculty dentistry Venezuela Central University Centre. Materials and methods: review retrospective 52 records in children presented in mouth's first molar permanent 26 children HIV (+) and 26 children HIV (-) children of mothers HIV (+); the period 2006 la statistical methodology was proof of Pearson. Results: when comparing the presence of caries in children HIV (+) found affected teeth 57,6 % while that only 11.5 % I note in the HIV (-), when you apply the Pearson test weeding a value p = 0, 01 and or = 7.3 * what represents a high statistical significance. Conclusion: Is well established the importance of the pediatric dentist in the interdisciplinary team that handles the HIV children, on who will bear responsibility for control of decay, predisposing factors, dental preventive and educational measures and systemic local factors result of the infection


Assuntos
Humanos , Masculino , Feminino , Criança , Criança , Cárie Dentária/imunologia , Dente Molar/patologia , HIV , Doenças Transmissíveis , Odontologia
5.
Trop Anim Health Prod ; 42(3): 531-7, 2010 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-19779843

RESUMO

There is a paucity of quantitative data on the status of porcine cysticercosis in Venezuela, information which is essential for understanding the level of disease transmission. This study was, therefore, conducted in a typical small rural community in Yaracuy State, Venezuela, where previous cases of human Taenia solium taeniasis/cysticercosis had been reported and where the free-ranging pig management practices and the lack of rudimentary sanitary facilities indicated an obvious risk for transmission of the disease. Serum samples from 52 village pigs were screened by enzyme-linked immunosorbent assays for anti-cysticercal antibodies (Ab-ELISA), using T. solium cyst fluid as the antigen and the HP10, monoclonal antibody-based, antigen trapping ELISA for parasite antigen (HP10 Ag-ELISA). Significantly, a high proportion of the animals (65.4% for the Ab-ELISA and 42.3% for the HP10 Ag-ELISA) were sero-positive. Five of the pigs, which were selected on that basis of positive tongue palpation, were killed for autopsy, and large numbers of viable cysticerci were found in the carcases. This unequivocal documentation of porcine cysticercosis in Venezuelan pigs presents clear evidence that T. solium is actively transmitted in Venezuela. Further detailed studies and implementation of appropriate control measures are therefore indicated.


Assuntos
Cisticercose/veterinária , Doenças dos Suínos/transmissão , Criação de Animais Domésticos , Animais , Cisticercose/epidemiologia , Cisticercose/transmissão , Ensaio de Imunoadsorção Enzimática/veterinária , Estudos Soroepidemiológicos , Suínos , Doenças dos Suínos/epidemiologia , Doenças dos Suínos/parasitologia , Venezuela/epidemiologia
6.
Alimentaria ; (308): 29-33, dic. 1999. tab
Artigo em Espanhol | CUMED | ID: cum-16890

RESUMO

Se estudian lso metodos empleados para la conservacion de un prteparado antianemico a base de sangre. Se analizaron las caracteristicas fisicoquimicas, microbiologicas y sensoriales del producto. Debido a los obstaculos usados para su conservacion, el producto posee una alta calidad higienica, pero esta puede ser mejorada mediante el uso de la energia ionizante. Se aislo e identifico la microflora presente. Se realizo un estudio radiobiologico de las cepas aisladas y se determino la dosis de reduccion decimal del microorganismo mas resistente. Se aplicaron dosis de 1 kGy para eliminar 10 3 cel/g de la cepa. No se produjeron cambios en las caracteristicas fisicoquimicas de las muestras despues de su irradiacion. Se detectaron cambios en las propiedades sensoriales del producto irradiado, pero este no es rechazable. Las radiaciones gamma mejoran la calidad higienica del producto (AU)


Assuntos
Conservação de Alimentos/métodos , Preservação de Sangue/métodos , Anemia/terapia
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