Hipo. Actitud en otorrinolaringología en pacientes que consultan. Aproximación diagnóstica y terapéutica / Hiccups. Attitude in otorhinolaryngology towards consulting patients. A diagnostic and therapeutic approach

Introducción. Las crisis de hipo suelen ser autolimitadas y benignas, pero los episodios prolongados alteran la calidad de vida y requieren asistencia, ya que existen causas identificables que el otorrinolaringólogo debe conocer para su diagnóstico y tratamiento. Su manifestación última es un ruido glótico espasmódico con alteraciones cervicales características. Pacientes y métodos. Desde 1979 se revisaron todos los casos que consultaron por hipo persistente o recidivante, anotando cronobiología, patología concomitante, resultados de las exploraciones, tratamiento y respuestas al mismo. Resultados. Se asistieron 37 pacientes con una edad media de 45,5±13,5 años, de los cuales 30 eran varones; 23 pacientes (el 62%) presentaron hipo persistente. En 24 casos (el 65%) se evidenció una causa potencialmente asociable: enfermedades del esófago en 14 —la mayoría reflujo gastroesofágico— y en 8 se apreció o descubrió patología oncológica concomitante. Solo 3 casos fueron intervenidos como resultado de los hallazgos efectuados. Los protocolos de tratamiento incluyeron metoclopramida en 18 sujetos, clorpromazina en 17 y baclofeno en 13, pero también carbamazepina o haloperidol. Se empleó neuroestimulación del nervio frénico en 6 pacientes. El hipo desapareció en 32 casos. De los 22 sujetos en los que se pudo efectuar seguimiento, se constató recidiva en 5 —precisando por ello nuevas terapias— y 11 fallecieron. Conclusiones. El hipo crónico implica un reto multidisciplinar con potencial afectación en cabeza y cuello, una sistemática diagnóstica de descarte, frecuente patología de base esofágica y una incidencia de neoplasia maligna alta. Los agentes procinéticos y neurolépticos con efecto antidopaminérgico y anticolinérgico suponen la base del tratamiento (AU)

Introduction. Hiccup crises are generally benign and self-limiting, but longer episodes affect quality of life and must be treated. There are recognisable causes that otorhinolaryngologists must know and be aware for diagnosis and therapeutic alternatives. The main expression is a spasmodic glottic noise with characteristic neck alterations. Patients and methods. This was a retrospective study from 1979 with patients suffering persistent or recurrent hiccups. Chronobiology, comorbidity, findings from explorations, therapies and outcomes were noted. Thirty-seven patients were studied (mean age, 45.5±13.5 years; 30 males), with persistent hiccups in 23 (62%). Results. A potential associated aetiology was observed in 24 cases (65%): oesophageal disorders —mainly gastroesophageal reflux— were detected in 14 cases and concomitant oncological disease was found in 8. Only 3 cases were admitted for surgery due to these findings. Therapeutic strategies with metoclopramide were used in 18 subjects, chlorpromazine in 17 and baclofen in 13, while carbamazepine or haloperidol were used in a minority. Phrenic nerve stimulation was employed in 6 patients. Hiccups disappeared in 32 cases. Out of 22 cases for which follow-up was possible, the hiccups recurred in 5 subjects (the subjects requiring new therapies) and 11 patients died. Conclusions. Chronic hiccup represents a multidisciplinary challenge that includes potential head and neck affection, a diagnostic schedule for ruling out causes, frequent base oesophageal alterations and high incidence of malignant neoplasm. Prokinetic and neuroleptic agents with antidopaminergic and anticholinergic effects are the pillars of its treatment (AU)

Hiccups. Attitude in Otorhinolaryngology Towards Consulting Patients. A Diagnostic and Therapeutic Approach. / Hipo. Actitud en otorrinolaringología en pacientes que consultan. Aproximación diagnóstica y terapéutica.

INTRODUCTION: Hiccup crises are generally benign and self-limiting, but longer episodes affect quality of life and must be treated. There are recognisable causes that otorhinolaryngologists must know and be aware for diagnosis and therapeutic alternatives. The main expression is a spasmodic glottic noise with characteristic neck alterations. PATIENTS AND METHODS: This was a retrospective study from 1979 with patients suffering persistent or recurrent hiccups. Chronobiology, comorbidity, findings from explorations, therapies and outcomes were noted. Thirty-seven patients were studied (mean age, 45.5±13.5 years; 30 males), with persistent hiccups in 23 (62%). RESULTS: A potential associated aetiology was observed in 24 cases (65%): oesophageal disorders -mainly gastroesophageal reflux- were detected in 14 cases and concomitant oncological disease was found in 8. Only 3 cases were admitted for surgery due to these findings. Therapeutic strategies with metoclopramide were used in 18 subjects, chlorpromazine in 17 and baclofen in 13, while carbamazepine or haloperidol were used in a minority. Phrenic nerve stimulation was employed in 6 patients. Hiccups disappeared in 32 cases. Out of 22 cases for which follow-up was possible, the hiccups recurred in 5 subjects (the subjects requiring new therapies) and 11 patients died. CONCLUSIONS: Chronic hiccup represents a multidisciplinary challenge that includes potential head and neck affection, a diagnostic schedule for ruling out causes, frequent base oesophageal alterations and high incidence of malignant neoplasm. Prokinetic and neuroleptic agents with antidopaminergic and anticholinergic effects are the pillars of its treatment.

Factores relacionados al dolor postamigdalectomía en adultos / Factors related to post-tonsillectomy pain in adults

Objetivo: Valoración de factores relativos a la anatomía faríngea y a la técnica quirúrgica como posible causa de dolor postamigdalectomía. Material y métodos: Estudio longitudinal prospectivo sobre 42 pacientes amigdalectomizados mediante disección con bisturí frío y monopolar, cuantificando los tiempos quirúrgicos y de empleo de electrobisturí, tamaño amigdalar, el dolor postoperatorio mediante escala analógica visual (EAV) y test de 40 ítems (QoR-40) y sus secuelas en la tolerancia oral, pérdida de peso y la estancia hospitalaria. Las correlaciones entre variables cuantitativas se establecieron mediante coeficientes de regresión lineal. Resultados: La amigdalectomía duró 22,66 ± 7,07 minutos, retirando amígdalas con un volumen medio de 6.046,07 ± 3.866,20 mm3 y empleando electrocauterio 66,14 ± 37,77 segundos para aplicar 1.984,24± 1.133,32 julios por paciente. El Mallampatti más frecuente se estadió en los estadios 2 y 3, y el tamaño amigdalar fue mayoritariamente entre 2-3. La EAV se elevó y el índice QoR-40 descendió a las 24 horas y a los 7 días de forma estadísticamente no significativa. La cantidad de julios administrados fue la variable que mejor se correlacionó con el malestar medido en las escalas, los requerimientos de analgesia y corticoides, la pérdida de peso y la estancia hospitalaria. El dolor fue más acusado entre sujetos en los que existió manipulación quirúrgica de tejido periamigdalino. Conclusiones: La mejoría en el empleo de las técnicas de electrodisección con aplicaciones más limitadas y focalizadas de energía y la preservación de la mucosa periamigdalar son factores que podrían aliviar el nivel de dolor postamigdalectomía (AU)

Objective: Assessment of factors related to pharyngeal anatomy and surgical technique as possible causes of post-tonsillectomy pain. Materials and methods: This was a prospective observational study that included 42 patients undergoing tonsillectomy with cold and monopolar electric device dissection. We recorded duration of the entire operation, duration of electrocautery use, tonsil size and postoperative pain and discomfort assessed using a visual analogue scale (VS) and a 40-item questionnaire (QoR-40, Quality of Recovery), along with sequelae on returning to normal diet, weight loss and hospital stay. Correlations among quantitative variables were obtained by mean of lineal regression coefficients. Results: Duration of surgery was 22.66 ± 7.07 minutes, removing tonsils with a volume of 6046.07 ± 3866.20 mm3 and an electrocautery use time of 66.14 ± 37.77 seconds, applying 1984.24 ± 1133.32 joules per patient. The most frequently observed Mallampati classification and tonsil size scores were stages II and III. The VS score increased and QoR-40 decreased at 24 hours and 7 days, but differences were statistically non-significant. Joule amount used for electrocautery was the parameter that correlated the best with discomfort status as measured via assessment scores, analgesic and corticosteroid requirements, weight loss and hospital stay. Pain was higher in subjects submitted to peritonsillar surgical aggression. Conclusions: Improved use of electrodissection techniques, limiting and focusing the application of its energy, and preservation of peritonsillar mucosa are factors that may lower post-tonsillectomy pain levels (AU)

Factors related to post-tonsillectomy pain in adults.

OBJECTIVE: Assessment of factors related to pharyngeal anatomy and surgical technique as possible causes of post-tonsillectomy pain. MATERIALS AND METHODS: This was a prospective observational study that included 42 patients undergoing tonsillectomy with cold and monopolar electric device dissection. We recorded duration of the entire operation, duration of electrocautery use, tonsil size and postoperative pain and discomfort assessed using a visual analogue scale (VS) and a 40-item questionnaire (QoR-40, Quality of Recovery), along with sequelae on returning to normal diet, weight loss and hospital stay. Correlations among quantitative variables were obtained by mean of lineal regression coefficients. RESULTS: Duration of surgery was 22.66 ± 7.07 minutes, removing tonsils with a volume of 6046.07 ± 3866.20 mm(3) and an electrocautery use time of 66.14 ± 37.77 seconds, applying 1984.24 ± 1133.32 joules per patient. The most frequently observed Mallampati classification and tonsil size scores were stages II and III. The VS score increased and QoR-40 decreased at 24 hours and 7 days, but differences were statistically non-significant. Joule amount used for electrocautery was the parameter that correlated the best with discomfort status as measured via assessment scores, analgesic and corticosteroid requirements, weight loss and hospital stay. Pain was higher in subjects submitted to peritonsillar surgical aggression. CONCLUSIONS: Improved use of electrodissection techniques, limiting and focusing the application of its energy, and preservation of peritonsillar mucosa are factors that may lower post-tonsillectomy pain levels.

Un caso de leishmaniasis laríngea / Laryngeal leishmaniasis. A case report

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Linfadenitis cervical debida a granuloma de silicona tras implantes mamarios / Neck lymphadenitis due to silicone granuloma after mammary implants

Introducción: La reacción a cuerpo extraño producida por la silicona donde se infiltra o en los territorios donde migra se conoce como siliconoma. Su empleo en las técnicas de aumento de pecho puede generar esta reacción en niveles cervicales si la cápsula del implante se rompe. Métodos: Se han revisado los casos que consultaron por adenopatías cervicales de tamaño elevado en pacientes previamente sometidos a cirugía plástica de mama con geles cohesivos de silicona. Resultados: En 10 años han sido constatados 12 casos con adenopatías cervicales infiltradas por silicona, confirmados mediante punción-aspiración con aguja fina. Suponen el 3,5% de todos los pacientes atendidos para estudio de adenopatías cervicales. Fueron retiradas aquellas detectadas por exploración física y TC en 5 casos, bien por presentar características patológicas o por historial previo de malignidad. En 2 casos intervenidos los ganglios reaparecieron, mientras que en 2 de los 7 pacientes donde se decidió no actuar, el volumen de las adenopatías también aumentó. Tras retirar los implantes, solo se observaron fugas en 7 casos. Conclusiones: La silicona empleada en geles cohesivos para implantes mamarios es susceptible de generar como efecto secundario el aumento del volumen de los ganglios linfáticos del cuello debido a reacciones sistémicas frente a la misma cuando migra. Las alternativas quirúrgicas de las adenopatías afectadas no suelen ofrecer buenos resultados a largo plazo (AU)

Introduction: A foreign body reaction due to silicone where it is infiltrated or at the places to which it can migrate is known as siliconoma. The use of silicone in breast augmentation procedures can provoke this reaction at the neck level in cases of leakage from mammary implants. Methods: We reviewed the cases of patients with increased size neck lymph nodes who had previously undergone plastic surgery of the breast with highly cohesive silicone gel implants. Results: In a 10-year period, we identified 12 cases with silicone-infiltrated neck lymphadenopathies, histologically confirmed by fine needle aspiration. They represented 3.5% of patients attended for neck lymph node study. We removed those detected by physical examination and CT in 5 cases, due to pathological characteristics of the node or a previous malignant history. In 2 of these nodes recurred, and node size also increased in 2 of the other 7 non-operated cases. After implant removal, silicone leakage was observed in only 7 cases. Conclusions: Cohesive gel silicone used for mammary implants can generate increased neck lymphadenopathies as a secondary effect due to systemic reactions against the silicone when it migrates in cases of implant failure. Surgical options for involved nodes usually do not offer good long-term results (AU)

Neck lymphadenitis due to silicone granuloma after mammary implants.

INTRODUCTION: A foreign body reaction due to silicone where it is infiltrated or at the places to which it can migrate is known as siliconoma. The use of silicone in breast augmentation procedures can provoke this reaction at the neck level in cases of leakage from mammary implants. METHODS: We reviewed the cases of patients with increased size neck lymph nodes who had previously undergone plastic surgery of the breast with highly cohesive silicone gel implants. RESULTS: In a 10-year period, we identified 12 cases with silicone-infiltrated neck lymphadenopathies, histologically confirmed by fine needle aspiration. They represented 3.5% of patients attended for neck lymph node study. We removed those detected by physical examination and CT in 5 cases, due to pathological characteristics of the node or a previous malignant history. In 2 of these nodes recurred, and node size also increased in 2 of the other 7 non-operated cases. After implant removal, silicone leakage was observed in only 7 cases. CONCLUSIONS: Cohesive gel silicone used for mammary implants can generate increased neck lymphadenopathies as a secondary effect due to systemic reactions against the silicone when it migrates in cases of implant failure. Surgical options for involved nodes usually do not offer good long-term results.

Deformabilidad eritrocitaria patológica en pacientes con sordera súbita / Pathologic erythrocyte deformability in patients with sudden sensorineural hearing loss

Objetivos: Evaluar si las propiedades viscoelásticas de la sangre influyen en la posibilidad de padecer sordera súbita o en la capacidad de responder a un tratamiento específico. Pacientes y métodos: Fueron estudiados 85 oídos de pacientes con sordera súbita, midiéndose el porcentaje de hipoacusia al inicio y el grado de recuperación a los 6 meses tras un tratamiento con corticoides y piracetam. También se anotó la presencia de acúfeno o síntomas vestibulares y se determinó en sangre periférica la filtrabilidad en sangre total (FST) y el índice de rigidez eritrocitaria (IRE). Resultados: La pérdida media al inicio clínico fue del 30,3±19,7% y a los 6 meses del 25,8±39%. En 41 oídos se observó una recuperación auditiva superior al 75% pasado este tiempo. En este grupo -el 48% del total- la FST se elevó y el IRE descendió (p<0,001 en ambos). Los oídos sin acúfeno ni vértigo recuperaron más audición a los 6 meses y mostraron mejoría significativa en su FST y en el IRE. El grado de hipoacusia al inicio se correlacionó con la FST y el de recuperación con el IRE, pero de forma estadísticamente no significativa. Los antecedentes de hipertensión arterial, cardiopatías e hipercolesterolemia fueron los más comúnmente detectados. Hipertensión e hiperuricemia mostraron mayor capacidad de recuperación. Conclusiones: Los parámetros de viscosidad sanguínea FST e IRE se correlacionan bien con el riesgo de padecer sordera súbita y la capacidad de una adecuada recuperación de la misma con terapias reoactivas(AU)

Objective: To evaluate if viscoelastic properties of blood influence suffering sudden sensorineural hearing loss and the capacity to respond after a specific therapy. Patients and methods: A longitudinal prospective study included 85 ears bearing sudden deafness. In them, the mean hearing loss compared to the healthy ear and the recovery ratio were measured at the onset and 6 months after a treatment with corticoids and piracetam. In addition, tinnitus or vestibular symptoms, whole blood filterability (WBF) and erythrocyte deformability -by means of the erythrocyte rigidity index (ERI)- were determined and noted at the beginning and the end of the study. Results: Mean hearing loss was 30.3±19.7% at the onset, and 25.8±39% at the end. Forty-one ears showed a recovery of more than 75%. In these (48% of the entire study group), an increase in WBF and a decrease in ERI were observed (P<.001). Ears without tinnitus or vestibular crisis recovered more hearing at 6 months and showed a significant improvement in WBF and ERI, not detected among patients with these clinical findings. There were good correlations between mean hearing loss at onset and WBF, and between recovery and ERI at 6 months, but without statistical significance. Patients with arterial hypertension, cardiopathy and hypercholesterolemia were the most frequently detected, while hypertension and hyperuricaemia showed a better hearing recovery ratio. Conclusions: The blood viscosity parameters WBF and ERI offer useful information about the risk of suffering sudden deafness and the capacity to recover hearing with reactive therapies(AU)

Pathologic erythrocyte deformability in patients with sudden sensorineural hearing loss.

OBJECTIVE: To evaluate if viscoelastic properties of blood influence suffering sudden sensorineural hearing loss and the capacity to respond after a specific therapy. PATIENTS AND METHODS: A longitudinal prospective study included 85 ears bearing sudden deafness. In them, the mean hearing loss compared to the healthy ear and the recovery ratio were measured at the onset and 6 months after a treatment with corticoids and piracetam. In addition, tinnitus or vestibular symptoms, whole blood filterability (WBF) and erythrocyte deformability -by means of the erythrocyte rigidity index (ERI)- were determined and noted at the beginning and the end of the study. RESULTS: Mean hearing loss was 30.3±19.7% at the onset, and 25.8±39% at the end. Forty-one ears showed a recovery of more than 75%. In these (48% of the entire study group), an increase in WBF and a decrease in ERI were observed (P<.001). Ears without tinnitus or vestibular crisis recovered more hearing at 6 months and showed a significant improvement in WBF and ERI, not detected among patients with these clinical findings. There were good correlations between mean hearing loss at onset and WBF, and between recovery and ERI at 6 months, but without statistical significance. Patients with arterial hypertension, cardiopathy and hypercholesterolemia were the most frequently detected, while hypertension and hyperuricaemia showed a better hearing recovery ratio. CONCLUSIONS: The blood viscosity parameters WBF and ERI offer useful information about the risk of suffering sudden deafness and the capacity to recover hearing with reactive therapies.