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BACKGROUND & OBJECTIVE: Pancreatic cancer is an uncommon type of cancer worldwide. Nonetheless, even with early diagnosis, mortality rates are high. This study aims to perform an epidemiologic profile of pancreatic cancer in Puerto Rico (PR) from 1987-2010. METHODS: Using data from the Puerto Rico Central Cancer Registry, age-standardized incidence and mortality rates of pancreatic cancer in PR were compared with Hispanics, non-Hispanic Whites, and non-Hispanic Blacks in the United States of America (USA). Incidence and mortality trends of pancreatic cancer were estimated, and survival analyses were also performed. RESULTS: In 2005-2010, 5.8 per 100,000 persons were diagnosed with pancreatic cancer in PR and mortality rates were similar. Pancreatic cancer was more frequent in men (6.5 per 100,000 men) than women (5.2 per 100,000 women), and in persons older than 65 years (32.0 per 100,000 persons). Moreover, the median survival for the people diagnosed with pancreatic cancer in PR during 2006-2007 was 4 months and at the end of the third year after diagnosis, only 13% of the patients survived. Incidence trends of pancreatic cancer showed an increase for men (APC=13.0%, p<0.05) from 2006 to 2010, but not for women (APC=-0.4, p>0.05). However, mortality trends showed a slight decrease for men (APC=-1.0%, p<0.05), but not for women (APC=1.4, p>0.05) in the period of 1987 to 2010. Meanwhile, Puerto Ricans in comparison to other racial/ethnic groups living in the USA showed a lower risk for being diagnosed and of dying from pancreatic cancer. CONCLUSION: Our results highlight the need for additional research in pancreatic cancer, in order to have an impact in disease survival in PR.
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Se realizó un estudio descriptivo retrospectivo de seis años de trabajo del departamento de Imagenología del Hospital Universitario Camilo Cienfuegos de Sancti Spíritus desde julio de 1998 hasta junio del 2004, para correlacionar los resultados de la sialografía y la ultrasonografía con el diagnóstico anatomopatológico de las lesiones que afectan las glándulas salivares mayores. Se conformó una serie de 70 pacientes con los requisitos para el estudio, 45 masculinos y 25 femeninos, con un rango de edades entre 15 y 82 años. La muestra la constituyeron 36 masas intraglandulares, 22 procesos inflamatorios crónicos no obstructivos, 10 procesos inflamatorios crónicos obstructivos y 2 abscesos simples, los que se clasificaron mediante la observación y análisis de las imágenes en 5 patrones sialográficos y 9 ultrasonográficos que permitieron agrupar las afecciones obtenidas en la muestra. En los resultados obtenidos se encontró asociación de los patrones sialográficos II y ultrasonográfico F en el 50 por ciento de los tumores, de los patrones sialográficos III y ultrasonográfico B en alrededor del 70 por ciento de los procesos inflamatorios crónicos no obstructivos y de los patrones sialográficos V y ultrasonográfico I en el 80 por ciento de las sialolitiasis, por lo que el estudio orienta que ambas técnicas se complementan(AU)
A retrospective/descriptive study of six years of work at the Imagenology Department of the Camilo Cienfuegos University Hospital of Sancti Spíritus from July of 1998 to June of 2004 was carried out to correlate the results of a sialography and an ultrasonography with the anatomopathological diagnosis of lesions that affect the major salivary glands. A series of 70 patients with the requirements for the study, 45 males and 25 females was made up, with an age range between 15 and 82 years. The sample was made up of 36 intraglandular masses , 22 chronic non-obstructive inflammatory processes, 10 chronic obstructive inflammatory processes and 2 simple abscesses, which were classified by observing and analyzing images in 5 sialographic and 9 ultrasonographic patterns that allowed to group the affections obtained in the sample. In the results obtained, an association was found of the sialographic II and ultrasonographic F patterns in 50 percent of the tumors, of the sialographic III and ultrasonographic B patterns in around 70 percent of the chronic non-obstructive inflammatory processes, and of the sialographic V and ultrasonographic I patterns in 80 percent of the sialolithiases, therefore the study indicates that both techniques complement each othe(AU)
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Humanos , Doenças das Glândulas Salivares/radioterapia , Doenças das Glândulas Salivares , Epidemiologia Descritiva , Epidemiologia DescritivaRESUMO
El carcinoma del pulmón fue descrito a mediados del siglo XIX como una neoplasia poco frecuente, pero en los últimos años ha adquirido una frecuencia alarmante, asociado esto principalmente al consumo del tabaco, por lo que se hace necesario revisar los aspectos sociales, económicos, políticos, jurídicos, psicológicos y bioéticos entre otros, para así poder brindar una atención integral a los pacientes con esta enfermedad(AU)
Lung carcinoma was described in the middle of the XIX century as a not very frequent neoplasia, but in the last few years it has acquired an alarming frequency, associated mainly to tobacco use. Therefore, it becomes necessary to review the social, economic, political, juridical, psychological and bioethical aspects among others, so as to provide in this way an integral attention to patients with this disease(AU)
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Neoplasias Pulmonares/psicologia , Bioética , Condições SociaisRESUMO
La anatomía del Túnel del Carpo se dice que es única. El nervio mediano ocupa una situación superficial con respecto a los tendones flexores por debajo del tenso ligamento carpiano transverso y como literalmente se expresa es un túnel por donde transita una estructura tan sensible como el nervio mediano. El síndrome del Túnel del Carpo es quizás la más estudiada y mejor definida neuropatía por atropamiento, casi siempre afecta el sexo femenino más que el masculino(3:1) y una edad comprendida entre 40 años y 60 años. Esta casuística la componen 102 casos, operados en un período de 2 años (1997-1999) en el Hospital Camilo Cienfuegos entre los Servicio de Neurocirugía y Ortopedia. De este total 77 (75 por ciento) fueron del sexo femenino, correspondiendo este dato con la literatura internacional que habla de la alta incidencia femenina. Desde el inicio de la posibilidad quirúrgica han existido grupos clasificatorios para tratar de hablar del futuro posquirúrgico y hacer posible el diagnóstico de esta enfermedad. La más acertada es la de D. Dawson y Colbs, en 1983.Se explicó la técnica de este proceder y los resultados obtenidos en estos 2 años, experiencia única en Cuba, y en el mundo, realizada en el Hospital Provincial Universitario de Sancti Spíritus. Se analizaron parámetros como: edad de casos operados en un espacio de 2 años (1997-1999)), clasificación internacional por grupos, síntomas con velocidad de conducción nerviosa y cambios microquirúrgicos(AU)
The anatomy of the carpus tunnel is said to be unique. The medium nerve ocuppies a superficial situation with regard to the flexor tendons, below the tense transverse carpal ligament, and, as literally expressed, it is a tunnel along which such a sensitive structure as the medium nerve traverses. The syndrome of the carpus tunnel is maybe the more studied and better defined neuropathy by grouping?(atropamiento). It almost always affects the female sex more than the male one(3:1) and an age between 40 years and 60 years. This statistics is composed by 102 cases, operated in a 2 year period (1997-1999) at the Camilo Cienfuegos Hospital between the Service of Neurosurgery and Orthopedics. Of this total, 77 (75 percent) were of the female sex, with this fact coinciding with the international literature that shows a high female incidence. Since the beginning of the surgical possibility, classification groups have existed to try to speak of the postsurgical future, and to make possible the diagnosis of this disease. The most correct is that of D. Dawson and Colbs, in 1983. The technique of this procedure and the results obtained in these 2 years were explained, in a unique experience in Cuba, and in the world, carried out at the Provincial University Hospital of Sancti Spíritus. An analysis was made of parameters such as: age of cases operated in a 2 year period (1997-1999)),international classification by groups, microsurgical symptoms. with speed of nervous conduction and changes(AU)
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/cirurgia , MicrocirurgiaRESUMO
En Cuba el cáncer de mama es la localización más frecuente entre las neoplasias malignas en la mujer y el segundo lugar entre las diez localizaciones más frecuentes de cáncer en ambos sexos, representando el primer lugar entre las causas de mortalidad por el cáncer para el sexo femenino.
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Humanos , Feminino , Neoplasias da Mama , Programas Nacionais de SaúdeRESUMO
The taxonomic position of Agromyces fucosus subsp. hippuratus is revised on the basis of molecular and phenotypic data. Phylogenetic analysis based on 16S rRNA gene sequences, DNA-DNA relatedness values and differences from other species in phenotypic traits revealed in this and earlier studies suggested reclassification of A. fucosus subsp. hippuratus as a separate species, Agromyces hippuratus sp. nov., comb. nov. The type strain is VKM Ac-1352T (= JCM 9087T). An emended description of Agromyces fucosus is given.
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Actinomycetales/classificação , Actinomycetales/genética , Parede Celular/química , DNA Bacteriano/química , DNA Bacteriano/isolamento & purificação , DNA Ribossômico/química , DNA Ribossômico/isolamento & purificação , Ácidos Graxos/análise , Ácidos Graxos/isolamento & purificação , Genes de RNAr , Dados de Sequência Molecular , Hibridização de Ácido Nucleico , Filogenia , RNA Bacteriano/genética , RNA Ribossômico 16S/genética , Análise de Sequência de DNA , Ácidos Teicoicos/químicaRESUMO
We propose a strategy for the efficient screening of large libraries of amplified 16S rRNA genes from complex environmental samples. It consists of processing sets of multiple clones simultaneously. This strategy saves up to 90% of the costs and labor spent in the process of screening a 16S rDNA library.
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Impressões Digitais de DNA/métodos , DNA Bacteriano/análise , Microbiologia Ambiental , Biblioteca Gênica , RNA Ribossômico 16S/análise , DNA Bacteriano/química , DNA Bacteriano/genética , Reação em Cadeia da Polimerase , RNA Ribossômico 16S/química , RNA Ribossômico 16S/genéticaRESUMO
The holy water fonts from the churches of Seville, Spain have a strong bacterial contamination. Coliforms, Enterobacteriaceae and other pathogenic bacteria are widely represented in the fonts investigated. Thirty out of the 37 different species isolated from holy waters are known human pathogens. The high bacterial contamination is related to human skin transmission and, probably, to misuse of the water.
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Bactérias/isolamento & purificação , Catolicismo , Microbiologia da Água , Cloreto de Sódio/químicaRESUMO
Lindane (gamma-HCH), a multipurpose organochlorine pesticide, was administered to Rattus norvegicus at acute and subchronic dosages. The dosage given was half that corresponding to LD50 (half the lethal dose). For rats, this is 60 mg/kg of body weight. The acute dose was administered on a single occasion, while the subchronic dosage was administered on 10 occasions over a 30-day period. Six types of behavior pattern based on the neurotoxic register were established for the acute dosage. Significant decreases in the levels of the neurotransmitter dopamine were also found, in similar proportions for both types of dose. The difference between single dose intoxication and poisoning by overlapping doses must be underlined, as the second type may produce the same effects without giving rise to clear symptoms.
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Comportamento Animal/efeitos dos fármacos , Dopamina/metabolismo , Hexaclorocicloexano/intoxicação , Sistema Nervoso/efeitos dos fármacos , Administração Oral , Animais , Diencéfalo/química , Feminino , Hexaclorocicloexano/administração & dosagem , Masculino , Fenômenos Fisiológicos do Sistema Nervoso , Ratos , Ratos WistarRESUMO
Se hace una revisión sobre el tratamiento de las malformaciones arteriovenosas cerebrales: cirugía, terapia endovascular(Embolización), tratamiento conservador y radiocirugía.(AU)
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Humanos , Malformações Arteriovenosas/terapiaRESUMO
Se hace una revisión sobre el tratamiento de las malformaciones arteriovenosas cerebrales: cirugía, terapia endovascular(Embolización), tratamiento conservador y radiocirugía.(AU)
