Factors related to muscle strength in postmenopausal women aged younger than 65 years with normal vitamin D status.

Objective: The study aimed to determine the impact of age, age at menopause, body mass index (BMI), and lumbar and hip bone mineral density (BMD) on muscle strength in young postmenopausal women with normal vitamin D levels. Methods: This was a cross-sectional study performed in 392 postmenopausal women aged <65 years with normal serum 25-hydroxyvitamin D levels (≥30 ng/ml) and no physical disabilities. The following variables were recorded: age, age at menopause, BMI, BMD (measured by dual-energy X-ray absorptiometry [DXA] scanning and expressed as lumbar and hip T-scores), and dominant hand grip strength (measured with a digital dynamometer). Results are reported as mean ± standard deviation or odds ratio (OR) and 95% confidence interval (CI) as appropriate. Results: The mean age of the whole sample was 57.30 ± 3.69 years with a mean age at menopause of 50.46 ± 2.16 years and a mean BMI of 24.93 ± 3.78. Mean DXA results were lumbar T-score of -1.16 ± 1.18 and hip T-score of -0.98 ± 0.93. The mean dominant hand grip force was 24.10 kg. A total of 12.2% (48/392) of women were diagnosed with dynapenia using a cut-off value of <20 kg. A weak but significant inverse correlation was found between grip strength in the dominant hand and age (r = -0.131, p = 0.009). Multivariable logistic regression analysis determined that earlier age at menopause (50 years or younger) was significantly associated with a higher risk of dynapenia (OR 2.741, 95% CI 1.23-6.11, p = 0.014). No other significant association was found with the other variables. Conclusions: A total of 12.2% of the studied young postmenopausal women with normal vitamin D status had dynapenia. There was a weak inverse correlation between grip strength and age, and earlier age at menopause was associated with an increased dynapenia risk.

Biological and pathological features in pregnancy-associated breast cancer: a matched case-control study.

BACKGROUND: The prognosis for breast cancer has been considered to be worsened by the coexistence of pregnancy. However, to date, significant controversy still exists regarding the pathological tumor features and prognosis of patients diagnosed with pregnancy-associated breast cancer (PABC). The aim of the present study was to analyze the different prognostic factors and outcome in PABC subset versus a non-PABC control group matched for age and year of diagnosis. MATERIALS AND METHODS: A total of 56 PABC cases were diagnosed from 1990 to 2008, for whom 73 non-PABC patients were identified. Pathological characteristics, immunohistochemical fea- tures, and differences in overall and disease-free survival were compared between both groups. RESULTS: Compared to non-PABC controls, PABC patients presented more advanced disease (31% vs 13%, p = 0.024) and greater lymph node involvement (53% vs 34%, p = 0.034). Pathological and tumor features tended to present poorer prognostic factors in the PABC subset. Survival was poorer in the PABC patients (five-year DFS 68% in PABC vs 86% in non-PABC, p = 0.12). However, analysing survival adjusted for stage and age, the authors did not find significant differences between both groups. CONCLUSIONS: PABC patients tended to be diagnosed in advanced breast disease and presented tumors with adverse pathological prognostic factors. While the authors found a poorer outcome in PABC group, no significant differences were observed with stage-matched analysis. The present results may suggest that the poorer prognosis observed within PABC women could not be due to pregnancy itself, but with a delay in diagnosis and tumor subtype pathological features.

Impact of Surgery on the Evolution of Uterine Sarcomas.

STUDY OBJECTIVE: To identify the characteristics of uterine sarcomas and assess the impact of morcellation on prognosis. DESIGN: Case-control study. (Canadian Task Force classification II-2). SETTING: Hospital Quiron-Dexeus, an academic hospital. PATIENTS: Patients with uterine sarcoma histologically diagnosed and treated in our center between 1987 and 2013. INTERVENTION: All descriptive data, including type of surgery and clinical and pathological data, were reviewed. Survival analysis was performed comparing patients with hysterectomy/myomectomy without any type of morcellation and patients with morcellation during surgery. MEASUREMENTS AND MAIN RESULTS: A total of 37 sarcomas were diagnosed during the study period. The most common symptom was metrorrhagia (50%). The indication for surgery was related to myoma growth in 40% of cases and to metrorrhagia in 37.1% of cases. Open surgery was performed in 23 patients (62.2%), and laparoscopy was performed in 9 (24.3%). Myomectomy was performed in 14 patients (37.8%), and 23 patients (62.1%) underwent hysterectomy as initial surgery. Morcellation for tumor extraction was done in 8 cases (21.6%). Survival analysis by surgical approach showed increased disease-free survival (DFS) in the laparotomy group compared with the laparoscopy group (median, 70.3 months vs 10.4 months; p = .018). Median DFS according to type of surgery was 6.3 months in morcellation cases, 11.9 months in vaginal fragmentation cases, and 149.9 months in nonmorcellated cases (p < .002). The median time to progression was shorter in morcellated cases (laparocopic and vaginal) compared with nonmorcellated cases (11.9 vs 14.9 months; p < .001). No statistically significant differences in prognosis were related to myomectomy versus hysterectomy; however, there were significants difference between morcellation and nonmorcellation cases. CONCLUSION: Taking into account the negative impact of morcellation in sarcomas, the use of this technique should be reconsidered in cases of myoma with atypical clinical presentation or symptomatology. Patients must be informed about the possibility of a nonidentified sarcoma and the possible impact on prognosis resulting from its morcellation.

Hormone receptor and HER2 status: The only predictive factors of response to neoadjuvant chemotherapy in breast cancer.

We report our experience in neoadjuvant breast cancer chemotherapy in a single centre between 2000 and 2011. We looked for predictive factors for response to neoadjuvant chemotherapy in the present study. A total of 110 consecutive breast cancer patients were treated with neoadjuvant chemotherapy in our centre. Pathological response was achieved in 24 HR+/HER2- (38.7%), 25 HER2+ (67.6%) and five triple-negative (45.5%) (p = 0.02) patients. No statistically significant differences were found in pathological tumour response according to T stage. The multivariate analysis revealed tumour subtype was the only associated factor for pathological response, with HER2 + tumours the best responders, OR 3.9 (1.5-9.9): 5-year DFS was 40% HER2+/no response; 78% HER2+/response; 65% HR+/HER2-/no response; 82% HR+/HER2-/response; 25% triple-negative/no response and 100% triple-negative/response. HR and HER2 status were the only prognostic factors for pathological response. pCR was correlated with survival in all tumour subtypes.

Crecimiento de novo de un hemangioma capilar conjuntival / De novo growth of a capillary hemangioma of the conjunctiva

CASO CLÍNICO: Mujer de 22 años, diagnosticada previamente de quiste de inclusión conjuntival en el sector nasal del ojo izquierdo y tratada mediante dos drenajes incisionales, que acude a nuestra consulta con hiposfagma universal acompañado de intenso dolor. Tras realizar una biopsia escisional, fue diagnosticada de hemangioma capilar conjuntival. DISCUSIÓN: El hemangioma capilar conjuntival es una lesión mayoritariamente benigna, asintomática y congénita, siendo rara pero posible su evolución o su aparición de novo en edades adultas

CLINICAL CASE: A 22-year-old woman patient, diagnosed with an inclusion cyst of the conjunctiva in the nasal sector of the left eye, who after 2 shot/needle injections in the lesion came to our clinic with a dense subconjunctival hemorrhage in four quadrants and with severe pain. After excision biopsy, a capillary hemangioma of the conjunctiva was diagnosed. DISCUSSION: Conjunctival capillary hemangioma is mainly a benign lesion, asymptomatic and mostly congenital in origin, its progression or de novo growth is rare in adulthood

[De novo growth of a capillary hemangioma of the conjunctiva]. / Crecimiento de novo de un hemangioma capilar conjuntival.

CLINICAL CASE: A 22-year-old woman patient, diagnosed with an inclusion cyst of the conjunctiva in the nasal sector of the left eye, who after 2 shot/needle injections in the lesion came to our clinic with a dense subconjunctival hemorrhage in four quadrants and with severe pain. After excision biopsy, a capillary hemangioma of the conjunctiva was diagnosed. DISCUSSION: Conjunctival capillary hemangioma is mainly a benign lesion, asymptomatic and mostly congenital in origin, its progression or de novo growth is rare in adulthood.

Atypical ultrasonographic presentation of ovarian vein thrombosis.

Ovarian vein trombosis (OVT) is a pathologic entity classically considered as a postpartum complication and only rarely associated with other diseases. Due to its vague symptoms, it is usually underdiagnosed. However its consequences can be fatal. We report a case of an incidental finding of ovarian thrombosis in an asymptomatic 45-year-old woman who underwent surgery due to the ultrasonographic finding of a para-ovarian cyst.

Role of lymphadenectomy in endometrioid endometrial cancer.

OBJECTIVE: To assess the risk factors associated with node involvement. STUDY DESIGN: In the period 1990-2008 a total of 265 endometrial cancers were treated in the Institut Universitari Dexeus. We analysed the rate of myometrial invasion, tumour grade, histological type and node involvement. RESULTS: Overall, 86% of tumours were endometrioid, 5.3% papillary serous, 4.9% mixed and 2.6% endometrial stroma sarcoma. Among those with endometrioid histology, lymphadenectomy was not performed (NL) in 85 cases (37.2%), whereas pelvic lymphadenectomy (PL) or pelvic and aortic lymphadenectomy (PAL) was carried out in 84 (36.84%) and 59 patients (25.87%), respectively. In NL patients the overall disease-free survival (DFS) rate at five years was 92.8%. In the PL group, node involvement was observed in 2.4% of cases and the five-year DFS rate was 92.3%. Among PAL patients, 18.6% showed node involvement (72.7% positive pelvic nodes and 63.6% aortic). Aortic involvement was present in 5.9% of cases when there was no pelvic disease, whereas in the presence of positive pelvic nodes the rate of aortic involvement was 50%. The DFS rate at five years was 93.6%. Referring to the risk factors, when infiltration was > 50% of the myometrium, lymph node involvement occurred in 37% of cases and G3 tumors in 45.5%. CONCLUSIONS: Node involvement is more commonly observed in cases with > 50% myometrial invasion and G3, accounting for 25% of cases that can be considered as at-risk patients. When node involvement is present it is equally distributed between the pelvic and aortic levels. As node involvement is a predictive factor for distant metastasis, the 25% of patients considered to be at risk should undergo pelvic and aortic lymphadenectomy

Utilidad de la elastografía como técnica complementaria de la ecografía convencional en lesiones mamarias BI-RADS 3 / No disponible

Objetivo: Analizar la aportación de la elastografía como técnica complementaria de la ecografía convencional en el manejo de las lesiones mamarias BI-RADS 3 (probablemente benignas). Pacientes y métodos: Se revisaron de forma retrospectiva 45 lesiones mamarias clasificadas como BI-RADS 3 (American College of Radiology, Breast Imaging Reporting and Data System) examinadas con ecografía en modo B y posteriormente con elastografía. El grado de elasticidad de las lesiones se puntuó del 1 al 5 según la escala de Ueno (1-3: benignas; 4-5: malignas). El estándar de referencia fue el diagnóstico citológico en combinación con el seguimiento y/o el resultado histológico de la biopsia con aguja gruesa o biopsia quirúrgica. Resultados: La elastografía presentó una sensibilidad de 50%, especificidad de 90,7%, valor predictivo positivo de 20% y valor predictivo negativo de 97,5%. Cuarenta y tres de las 45 lesiones fueron citológica y/o histológicamente benignas. Treinta y nueve de las 43 lesiones benignas presentaban una puntuación elastográfica benigna (entre 1 y 3) y las 4 restantes tenían puntuación 4 (falsos positivos elastográficos). Todas las lesiones con puntuación elastográfica entre 1 y 3 fueron cito/histológicamente benignas excepto un caso, con diagnóstico histológico de carcinoma ductal infiltrante (falso negativo ecográfico y elastográfico). Conclusión: La elastografía puede ser de utilidad como técnica complementaria de la ecografía convencional en lesiones mamarias BI-RADS 3. La alta concordancia entre elastografía y cito/histología en el diagnóstico de estas lesiones podría disminuir el número de biopsias innecesarias y permitiría orientar a estas pacientes de bajo riesgo hacia un seguimiento(AU)

Objective: To analyze the contribution of elastography as a complementary technique of conventional ultrasound in the management of BI-RADS 3 breast lesions (probably benign). Patients and methods: 45 breast lesions classified as BIRADS 3 (American College of Radiology, Breast Imaging Reporting and Data System) have been retrospectively reviewed, all of them studied with conventional ultrasound and immediately after with real-time elastography. Elastographic images were classified according to Ueno’s five-score system. Scores 1-3 were considered benign and 4-5 malignant. Cytological diagnosis in combination with follow-up and/or histopathological result of a core-needle biopsy or surgical biopsy were used as the reference standard. Results: Elastography had a sensitivity of 50%, specificity of 90.7%, positive predictive value of 20% and negative predictive value of 97.5%. Forty-three of the 45 BI-RADS 3 lesions were cytologically and/or histologically benign. Thirtynine of the 43 benign lesions had a benign elastographic score (between 1 and 3) and the remaining 4 had score 4 (elastographic false positives). All lesions with benign elastographic score were benign except one case with histological diagnosis of infiltrating ductal carcinoma (false negative case). Conclusion: Elastography may be useful as a complementary technique of conventional ultrasound in BI-RADS 3 breast lesions. The high degree of concordance between elastography and cyto/histopathology in the diagnosis of these lesions could reduce the number of unnecessary biopsies and would allow for management of these low risk patients with follow-up(AU)

Three-dimensional power Doppler color ultrasonographic features of a minimal deviation adenocarcinoma of the uterine cervix.

A case of minimal deviation adenocarcinoma of the cervix in a 34-year-old female is presented. The ultrasonographic and three-dimensional power Doppler color studies revealed a nodular cervical lesion with vascularization more prominent in the center of the nodule but also present at the periphery. The imaging diagnosis was suggestive of a myoma but with more vascularization than a conventional one.

Biopsia con aguja gruesa de las lesiones mamarias bajo guía ecográfica / No disponible

Objetivo: Valorar la exactitud diagnostica de la biopsia con aguja gruesa bajo guía ecográfica según morfología, tamaño y clasificación BI-RADS de la lesión. Pacientes y métodos: Entre septiembre de 2007 y marzo de 2009 se realizaron 150 biopsias a 142 pacientes consecutivas con aguja gruesa de calibre 14G guiadas por ecografía. Fueron intervenidas 103 pacientes y 29 casos benignos se controlaron en 12-24 meses. 18 casos fueron excluidos por falta de seguimiento o traducción ecográfica. Resultados: Se biopsiaron 114 nódulos (86%) y 18 distorsiones (14%) en 130 pacientes con edad media de 49 años (rango 28-82). La sensibilidad, especificidad, VPP y VPN en nódulos fue: 92, 100; 100 y 86,7% y en distorsiones 92,9, 100, 100 y 80%. El tamaño medio fue de 15,7 mm (rango 3- 42 mm), con sensibilidad, especificidad, VPP y VPN de 84,2, 100, 100 y 81,3% en lesiones menores de 10 mm, 91,1, 100, 100 y 86,7% en lesiones entre 11 y 20 mm, y en lesiones mayores de 20 mm 100, 100, 100 y 100%. La sensibilidad, especificidad, VPP y VPN para BI-RADS 3 (n = 38, 29%) fue 88,9, 100, 100, 96,7; para BI-RADS 4 (n = 60, 45%) 87,2, 100, 100 y 68,4%, y para BI-RADS 5 (n = 34, 26%) 100, 100, 100 y 100%. 82 lesiones fueron malignas, 48 benignas y 2 lesiones de alto riesgo. Hubo 6 falsos negativos y tres infravaloraciones. Conclusión: La biopsia con aguja gruesa bajo guía ecográfica es una técnica fiable para el diagnóstico de lesiones mamarias independientemente de su morfología, variando el resultado según tamaño y categoría BI-RADS(AU)

Purpose: To determine the accuracy of ultrasound-guided breast core-needle biopsy related to lesion morphology, size and BI-RADS classification. Patients and methods: Between September 2007 and March 2009 150 ultrasound-guided 14G core needle biopsies were performed to 142 consecutive patients. 103 patients were surgically treated and 29 benign cases were followed up for 12-24 months. 18 cases were lost to follow-up or lacked sonographic correlation and were thus excluded. Results: 114 nodules (86%) and 18 distortions (14%) were biopsied in 130 patients (ages 28-82 years, mean 49 years). Sensitivity, specificity, PPV and PNV was 92, 100, 100 and 86,7% for nodules and 92.9, 100, 100% and 80% for distortions. Mean size of the lesions was 15.7 mm (range 3-42 mm), with sensitivity, specificity, PPV and PNV 84,2, 100, 100 y 81,3% for lesions less than 10 mm, 91,1, 100, 100 and 86,7% for lesions between 11 and 20 mm, and 100, 100, 100 and 100% for lesions larger than 20 mm. Sensitivity, specificity, PPV and PNV for BI-RADS 3 lesions (n = 38, 29%) was 88.9, 100, 100, 96.7%; for BI-RADS 4 (n = 60, 45%) 87.2, 100, 100 y 68.4%, and for BI-RADS 5 (n = 34, 26%) 100, 100, 100 y 100%. 82 lesions were malignant, 48 benign y 2 high risk lesions. 6 false negatives and three underestimation were found. Conclusion: Core needle biopsy under ultrasound guidance is an effective technique to diagnose breast lesions, independently of its morphology but depending on lesion size and BIRADS category(AU)

Tumor de células granulares de la mama / No disponible

El tumor de células granulares es una lesión poco frecuente y que ocasionalmente puede afectar a la glándula mamaria. Se presenta el caso de una mujer de 31 años con un nódulo en la mama derecha, mamográficamente benigno y ecográficamente sospechosa. La punción citológica y el estudio histológico demostraron un tumor de células granulares de la mama. Su extirpación completa fue curativa(AU)

Granular cell tumor is an infrequent lesion that can occur in the breast. Herein is presented a case of a 31-year-old female with a mammographically benign nodule but ultrasonographically suspicious in the right breast. Fine needle aspiration and histologic study revealed a granular cell tumor of the breast. The complete excision was curative(AU)

Hiperplasia intraductal atípica o carcinoma intraductal grado 1 vs. DIN1c / No disponible

Objetivo: La clasificación DIN incluye en el DIN1c la hiperplasiaintraductal atípica (HIA) y el carcinoma intraductal grado1 (CID1). El objetivo de este estudio es ver si esta agrupacióndiagnóstica, con las consecuencias terapéuticas que elloconlleva, implica o no un sobretratamiento de la HIA.Pacientes y métodos: Se ha revisado el tratamiento y laevolución de los casos de HIA y CID1 diagnosticados en nuestrocentro desde 1999 hasta 2008. Se han utilizado los mismoscriterios diagnósticos que utiliza la clasificación DIN paradiferenciar la HIA y el CID1.Resultados: De 117 casos, 49 fueron HIA y 68 CID1. Eltratamiento quirúrgico fue tumorectomía, independientementedel estado del margen, en 47 (96%) HIA y en 53 (78%) CID1consiguiendo siempre un margen libre. En 42 (62%) casos deCID1 el tratamiento se complementó con radioterapia. Uncaso de HIA y otro de CID1 recidivaron tras 24 y 39 mesesen forma de carcinoma ductal infiltrante.Conclusiones: La clasificación DIN simplifica el diagnóstico,no obstante agrupar alguna de estas lesiones puede conllevarsu sobretratamiento. En nuestra serie la simple extirpaciónde una HIA independientemente del estado del margen hasido curativa en la mayoría de casos(AU)

Objective: DIN classification includes into DIN1c the atypicalintraductal hyperplasia (AIH) and intraductal carcinomagrade 1 (IDC1). The aim of this study is to see if this grouping,with its therapeuthical consequences, implies an overtreatmentof AIH.Patients and methods: Treatment and follow-up of allthose cases diagnosed of AIH and IDC1 between 1999 and2008 at our centre have been revised. The diagnostic criteriato differentiate AIH and IDC1 were the same used in DIN classification.Results: Of the 117 studied cases, 49 were diagnosed asAIH and 68 as IDC1. Lumpectomy, independently of the statusof the margin was performed in 47 (96%) AIH, and 53(78%) IDC1 with adequate resection margin. In 42 (62%) casesof IDC1 adjuvant radiotherapy was given. One case of AIHand one case of IDC1 recurred as invasive ductal carcinoma,24 and 39 months later respectively.Conclusions: DIN classification simplifies the diagnosis butgrouping these lesions can result into an overtreatment. In ourserie the surgical excision of AIH independently of the statusof the margin was curative in the majority of the cases(AU)

Carcinoma oculto de la mama metastásico en ganglio intramamario / No disponible

Se presenta un caso de una mujer de 63 años con un nóduloen los cuadrantes externos de la mama derecha con característicasmamográficas y ecográficas de benignidad, en la queel estudio citológico evidencia un carcinoma, el cual histológicamentecorresponde a un ganglio linfático intramamario metastásicocon un primario en la glándula mamaria no detectado

A case of a 63-year old woman with a nodular lesion in theexternal quadrants of the right breast. The lesion was mammographicallyand ultrasonographically benign, but fine needleaspiration showed a carcinoma. Pathologic examinationrevealed a metastatic intramammary lymph node, but the primarycarcinoma in the breast could not be detected

Consideraciones a tener en cuenta al redactar un trabajo médico / No disponible

Siguiendo al título se desarrollara un resumen estructuradodel contenido del trabajo. Su extensión es variable enfunción de las normas de cada revista pero en general oscilaentre las 150-200 palabras. Se estructurará de forma que seexpliquen los objetivos del trabajo, los procedimientos básicosutilizados, los principales hallazgos y las conclusionesmás importantes(AU)

Lesiones hiperplásicas y preinvasivas precursoras del cáncer de mama: desde la epiteliosis hasta la neoplasia ductal intraepitelial / No disponible

No disponible

Carcinoma micropapilar infiltrante de la mama y biopsia del ganglio centinela / Infiltrating micropapillary carcinoma of the breast and sentinel lymph node biopsy

Objetivo: Las características histopatológicas del tumorpueden hacer que no sea posible la práctica de la biopsia delganglio centinela (BGC). El propósito de este estudio es evaluarla aplicación y los resultados de esta técnica en pacientescon carcinoma micropapilar infiltrante (CMI) de la mama.Pacientes y método: Durante los últimos siete años ennuestro centro se ha efectuado la BGC en 294 pacientes y sehan diagnosticado 37 CMI. Se trata de un estudio retrospectivode la técnica utilizada para la estadificación ganglionar enestas pacientes. Los resultados de la BGC en pacientes conCMI se comparan con los resultados de esta técnica en pacientescon otros tipos histológicos de cáncer de mama.Resultados: La BGC sólo pudo efectuarse en 8 (22%) delas pacientes con CMI. Cuatro presentaron metástasis, unamicrometástasis y dos células tumorales aisladas (CTA). Ensólo una de las pacientes se detectaron más ganglios afectadosen el resto de la linfadenectomía. En aquellas pacientes en lasque no se pudo realizar la BGC, las principales contraindicacionesfueron: el diagnóstico prequirúrgico de afectación ganglionarmediante punción aspiración con aguja fina guiadaecográficamente y la multifocalidad.Conclusiones: La BGC puede realizarse en pocas ocasionesen pacientes con CMI. Cuando esta puede efectuarse, elporcentaje de metástasis es alto aunque con frecuencia el centinelaes el único ganglio afectado

Objective: Hystopatologic tumor characteristics can carryfailure in the practice of sentinel lymph node (SLN) biopsy.The aim of this study is to evaluate the application and the resultsof this technique in patients with infiltrating micropapillarycarcinoma (IMPC) of the breast.Patients and method: During the last seven years in ourcenter SLN biopsy has been performed in 294 patients and37 IMPC have been diagnosed. This is a retrospective study ofthe technique used for nodal staging in these patients. The resultsof SLN biopsy in those patients with IMPC were comparedwith the results of this technique in patients with other histologicaltypes of breast cancer.Results: SLN biopsy could be done in only 8 (22%) patientswith IMPC. Four had metastases, one micrometastasisand two isolated tumor cells. Only one patient showed morelymph nodes involved in the axilla. In those patients in whomthe SLN biopsy could not be done, positive fine needle aspirationunder ulltrasonographic guidance and multifocal breast involvementwere the main contraindications.Conclusions: SLN biopsy is infrequently indicated in thosepatients with IMPC and, when performed, the percentageof lymph node metastasis is high but mostly limited to SLN

Condrolipoma de la mama detectado por microcalcificaciones mamográficas / Chondrolipoma of the breast detected by microcalcifications on mammography

Se presenta el caso de una paciente de 50 años de edad, con unas microcalcificaciones mamográficas de nueva aparición y sospechosas de malignidad. La lesión se extirpó quirúrgicamente y el examen microscópico evidenció una lesión constituida por islotes maduros de tejido adiposo y cartilaginoso con focos de calcificación y osificación. El condrolipoma es un tumor benigno del que hay pocos casos descritos en la bibliografía. Se presentan los aspectos clínicos e histológicos y se discuten los diagnósticos diferenciales y la etiopatogenia del tumor

The case of a 50-year-old woman with recently developed microcalcifications on mammogram which were suspicious for malignancy is presented. The lesion was surgically removed and histological examination revealed islands of mature adipose and cartilaginous tissues with calcifications and focal ossification. Chondrolipoma is a benign tumor and only a few cases have been reported in the literature. The clinical and histological features are described, and the differential diagnosis and etiopathogenesis are discussed