1.
Journal of Leukemia & Lymphoma
; (12): 374-377, 2022.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-953973
RESUMO
Chronic myeloid leukemia (CML) is a malignant tumor formed by clonal proliferation of bone marrow hematopoietic stem cells. With the improvement of disease awareness and the introduction of new drugs, more than 90% of CML patients can achieve long-term survival. However, a few patients still show drug resistance. This article reviews the mechanism of drug resistance in CML patients treated with tyrosine kinase inhibitor (TKI) and the characteristics of ABL kinase region mutation.