Climate impacts on reproductive performance of Romanov sheep in the moderate climate

This study aimed to investigate the climatological impacts of air temperature, sunshine duration, and rain precipitation, in a moderate climate, on the reproductive performance of Romanov sheep in the continental part of Croatia, during two consecutive years (2019-2020). Our study included 549 matings with 520 successful conceptions at 5 Romanov sheep farms, and the fertility rate was 94.72%. The percentage of lambs delivered in winter was 53.27% (n = 277), in spring 20.19% (n = 105), in summer 14.23% (n = 74) and 12.31% in autumn (n = 64). According to percentile ranks and classification ratings, thermal conditions have been described as very warm (during 2019-2020), while precipitation conditions, expressed in percentiles, were wet (during 2019) but dry (during 2020) for this region. The peak of sexual activity was from mid-August until October in 2019 and from the end of August to November in 2020 for Romanov sheep in northwestern (NW) Croatia. A Kruskal-Wallis test showed a statistically significant difference in the number of pregnant ewes during the different mating seasons in the year (p < 0.001). Therefore, we can assume that air temperature, precipitation volume, and sunshine duration during the different seasons could impact the reproductive performance of Romanov sheep in a moderate climate.

Protective effect of L-carnitine on myocardial injury in rats with heatstroke

Purpose: To investigate the protective effect of L-carnitine on myocardial injury in rats with heatstroke. Methods: orty-eight rats were randomly divided into control, heatstroke and 25, 50 and 100 mg/kg L-carnitine groups. The last three groups were treated with 25, 50 and 100 mg/kg L-carnitine, respectively, for seven successive days. Then, except for the control group, the other four groups were transferred into the environment with ambient temperature of (39.5 ± 0.4 °C) and relative humidity of (13.5 ± 2.1%) for 2 h. The core temperature (Tc), mean arterial pressure (MAP), heart rate (HR) and serum and myocardial indexes were detected. Results: Compared with the heatstroke group, in the 100 mg/kg L-carnitine group, the Tc was significantly decreased, the MAP and HR were significantly increased, the serum creatine kinase, lactate dehydrogenase, alkaline phosphatase, aspartate aminotransferase, tumor necrosis factor and interleukin 1 levels were significantly decreased, the myocardial superoxide dismutase and glutathione peroxidase levels were significantly increased, the myocardial malondialdehyde level was significantly decreased and the cardiomyocyte apoptosis index and myocardial caspase-3 protein expression level were remarkably decreased (p 0.05). Conclusions: The L-carnitine pretreatment can alleviate the myocardial injury in heatstroke rats through reducing the inflammatory response, oxidative stress and cardiomyocyte apoptosis.(AU)

Intermação em cães: revisão de literatura / Heatstroke in dogs: a review / El golpe de calor en los perros: revision de la Literatura

Quando o mecanismo de termorregulação do animal não consegue compensar a produção de calor ocorre a hipertermia. Sua ocorrência varia de animal para animal de acordo com condicionamento físico, hidratação, idade, obesidade, doença cardiopulmonar, hipertireoidismo e predisposição racial. Dentre as alterações provocadas pela injúria térmica, estão necrose celular, hipóxia, desnaturação proteica e sepse. A instituição rápida de um tratamento emergencial minimiza os danos causados pela hipertermia e suas consequências. O presente trabalho tem por objetivo auxiliar a identificação das manifestações clínicas e o tratamento desta síndrome.(AU)

When the animal's thermoregulatory mechanisms can not compensate for the heat production occurs hyperthermia. This occurrence varies from animal to animal according to fitness, hydration, age, obesity, cardiopulmonary disease, hyperthyroidism and racial predisposition. Among the changes caused by thermal injuryare cellular necrosis, hypoxia, protein denaturation and sepsis. The institution of a rapid emergency treatment minimizes damage caused by hyperthermia and its consequences.(AU)

Cuando los mecanismos de termorregulación de los animales no pueden compensar el calor hipertermia ocurre. Su aparición varía de un animal a otro de acuerdo a la aptitud, la hidratación, la edad, la obesidad, enfermedades cardiopulmonares, el hipertiroidismo y la predisposición racial. Entre los cambios causados por la lesión térmica son la necrosis celular, la hipoxia, la desnaturalización de la proteína y la sepsis. El rápido establecimiento de un tratamiento de emergencia reduce al mínimo los danos causados por la hipertermia y sus consecuencias. Este trabajo tiene como objetivo ayudar a identificar las manifestaciones clínicas y el tratamiento de este síndrome.(AU)

Intermação em cães: revisão de literatura / Heatstroke in dogs: a review / El golpe de calor en los perros: revision de la Literatura

Quando o mecanismo de termorregulação do animal não consegue compensar a produção de calor ocorre a hipertermia. Sua ocorrência varia de animal para animal de acordo com condicionamento físico, hidratação, idade, obesidade, doença cardiopulmonar, hipertireoidismo e predisposição racial. Dentre as alterações provocadas pela injúria térmica, estão necrose celular, hipóxia, desnaturação proteica e sepse. A instituição rápida de um tratamento emergencial minimiza os danos causados pela hipertermia e suas consequências. O presente trabalho tem por objetivo auxiliar a identificação das manifestações clínicas e o tratamento desta síndrome.

When the animal's thermoregulatory mechanisms can not compensate for the heat production occurs hyperthermia. This occurrence varies from animal to animal according to fitness, hydration, age, obesity, cardiopulmonary disease, hyperthyroidism and racial predisposition. Among the changes caused by thermal injuryare cellular necrosis, hypoxia, protein denaturation and sepsis. The institution of a rapid emergency treatment minimizes damage caused by hyperthermia and its consequences.

Cuando los mecanismos de termorregulación de los animales no pueden compensar el calor hipertermia ocurre. Su aparición varía de un animal a otro de acuerdo a la aptitud, la hidratación, la edad, la obesidad, enfermedades cardiopulmonares, el hipertiroidismo y la predisposición racial. Entre los cambios causados por la lesión térmica son la necrosis celular, la hipoxia, la desnaturalización de la proteína y la sepsis. El rápido establecimiento de un tratamiento de emergencia reduce al mínimo los danos causados por la hipertermia y sus consecuencias. Este trabajo tiene como objetivo ayudar a identificar las manifestaciones clínicas y el tratamiento de este síndrome.

Intermação: uma síndrome emergencial: revisão de literatura / Heat Stroke: a emergency syndrome: a review

Os distúrbios relacionados à homeostasia térmica são freqüentes na clínica de pequenos animais, sendo sua etiologia principalmente relacionada a processos infecciosos e inflamatórios. No entanto, há uma forma de hipertermia conhecida por intermação, onde o ponto referencial de temperatura no hipotálamo encontra-se normal e a termorregulação é perdida, devido à deficiência dos mecanismos responsáveis pela dissipação de calor. O excesso de calor produzido é responsável por elevações da temperatura corporal central que podem atingir 43ºC ou mais, resultando em lesão celular, morte celular, disfunções orgânicas e morte do animal, requerendo, dessa forma, intervenção emergencial

Disorders related to thermal homeostasis are common in the small animal clinical, whose etiology is mainly related to infectious and inflammatory processes. However, there is a form of hyperthermia known Heat stroke where the reference point of the hypothalamic temperature is normal and thermoregulation is lost due to deficiency of the mechanisms responsible for heat dissipation. Excess heat is responsible for elevations in core body temperature that can reach 43 degrees or more, resulting in cell damage, cell death, organ dysfunction and death of the animal, requiring thus emergency intervention

Intermação: uma síndrome emergencial: revisão de literatura / Heat Stroke: a emergency syndrome: a review

Os distúrbios relacionados à homeostasia térmica são freqüentes na clínica de pequenos animais, sendo sua etiologia principalmente relacionada a processos infecciosos e inflamatórios. No entanto, há uma forma de hipertermia conhecida por intermação, onde o ponto referencial de temperatura no hipotálamo encontra-se normal e a termorregulação é perdida, devido à deficiência dos mecanismos responsáveis pela dissipação de calor. O excesso de calor produzido é responsável por elevações da temperatura corporal central que podem atingir 43ºC ou mais, resultando em lesão celular, morte celular, disfunções orgânicas e morte do animal, requerendo, dessa forma, intervenção emergencial(AU)

Disorders related to thermal homeostasis are common in the small animal clinical, whose etiology is mainly related to infectious and inflammatory processes. However, there is a form of hyperthermia known Heat stroke where the reference point of the hypothalamic temperature is normal and thermoregulation is lost due to deficiency of the mechanisms responsible for heat dissipation. Excess heat is responsible for elevations in core body temperature that can reach 43 degrees or more, resulting in cell damage, cell death, organ dysfunction and death of the animal, requiring thus emergency intervention(AU)