Clinical and laboratory characteristics of HIV-1 infection in Zimbabwe

To define the impact of human immunolodeficiency virus (HIV) infection in Africa; clinical and laboratory investigations were conducted on 265 HIV-seropositive outpatients in Zimbabwe. Twenty-four of the study subjects were asymptomatic (ASX); 124 had persistent generalized lympademopathy (PGL); and 117 had AIDS-related complex (ARC). HIV infection was assessed by commercial ELISA; Western blots; synthetic peptide ELISA; and measurement of p24 antigen. Serum immunoglobulins; lympocyte mitogen responses; and CD4+ cell numbers were obrtained in 54 sequential patients. Compared to seronegative subjects meab CD4+ cell numbers were decreased and serum immunoglobulins; particularly IgM and IgG; were increased in all groups of seropositive subjects. [abstract terminated]

Report on AIDS preventions and control activities

The report covers last quarter of 1988 and first quarter of 1989. The main thrust of the short term plan (STP) was on information and education for the general public; training of health workers in various aspects of HIV infection and AIDS; development of the National Public Health Laboratory to have the capacity to test for HIV and the expansion and decentralization os the Blood Transfusion Service