ABSTRACT
"Atherosclerosis is known to be related to hypercholesterolemia and ""ABO"" blood group in non African adults. This study was undertaken to determine if such a correlation between high lipid fractions and ABO blood groups also exists in African population. Two hundred and two subjects were used in this study: 36.5 per cent of them belonged to the A blood group.; 14.8 per cent to the B blood group; 2 per to the AB blood group and 46.7 per cent to the O blood group. Blood group A subjects were found to be having high total cholesterol and ApoB level and a slight increase of LDL.C Level. Analysis of the variance showed that the cholesterol level of blood group A persons was significantly different from blood group B. ApoB level of blood group A subjects was significantly different from blood B or O. When separated into two sexes; there was no significant difference between the cholestrerol level of A blood group female and male; and between their ApoB level. Elevated level of cholesterol associated in blood group A persons with high ApoB level and high ApoB/ApoA1 ratio over 0.65 enable the authors to conclude that these persons belonged to a high cardiovascular risk group; and this disease could be prevented by an early diet management"