Susceptibilité d'appartenance à un groupe sanguin spécifique du système Abo des personnes atteintes de COVID-19 à l'Institut national de Santé Publique (INSP) en 2020 / Susceptibility of ABOS blood groups to COVID-19 at the National Institute of Public Health (INSP) Of Mali In 2020

Introduction: Plusieurs auteurs ont suggéré une association entre le système ABO (SABO) et le risque d'infection au SRAS CoV-2. La présente étude avait pour objectif d'identifier la susceptibilité des groupes sanguins du SABO au COVID-19à l'Institut National de Santé Publique (INSP) du Mali. Matériel et méthodes : Il s'agissait une étude cas-témoins non appariée. Les cas (402) étaient des patients COVID-19 et les témoins (5438) des pèlerins musulmans tous ayant fait le groupage sanguin ABO à l'INSP. Une régression logistique fut réalisée afin d'identifier les facteurs associés au statut infectieux à SRAS-CoV-2en utilisant le logiciel SPSS version25. Résultats: Les groupes sanguins avaient les fréquences suivantes : O(34%), B(30%), A(28%), AB(8%) pour les cas et O(42%), B(27%), A(25%), AB(6%) pour les témoins. Le statut COVID-19 positif n'était pas significativement associé aux groupes sanguins A(OR=1,17; IC95%[0,93-1,47]), B(OR=1,11; IC95%[0,89-1,39]) et AB(OR=1,41; IC95%[0,97-2,06]). Cependant, les sujets du groupe sanguin O étaient 28 fois moins susceptibles de faire la COVID-19 que les non O(OR=0,72; IC95%[0,58-0,89). Conclusion: Les résultats suggèrent que les personnes du groupe sanguin O étaient moins susceptibles de faire l'infection par le SRAS CoV-2 que les non O. Cela ne devrait pas influer sur l'utilisation des mesures barrières au sein des groupes SABO.

Introduction: Several authors have suggested an association between the ABO system (ABOS) and the risk of SARS CoV-2 infection. The objective of the present study was to identify the susceptibility of ABOS blood groups to COVID-19 at the National Institute of Public Health (INSP) of Mali. Material and methods: This was an unpaired case-control study. The cases (402) were COVID-19 patients, and the controls (5438) were Muslim pilgrims, all of whom had undergone ABO blood grouping at the INSP. Logistic regression was performed to identify factors associated with SARS-CoV-2 infection status using SPSS version25 software. Results: Blood types had the following frequencies: O(34%), B(30%), A(28%), AB(8%) for cases and O(42%), B(27%), A(25%), AB(6%) for controls. COVID-19 positive status was not significantly associated with blood groups A(OR=1.17; CI95%[0.93-1.47]), B(OR=1.11; CI95%[0.89-1.39]) and AB(OR=1.41; CI95%[0.97-2.06]). However, blood group O subjects were 28 times less likely to have COVID-19 than non-O(OR=0.72; CI95%[0.58-0.89). Conclusion: The results show that blood group O individuals were less likely to have SARS CoV-2 infection than non-O individuals. This should not affect the use of barrier measures in ABOS groups.

Association of COVID-19 severity with vitamin D and blood group

Abstract: Vitamin D is a hormone which plays a vital role in immune response regulation, including the prevention of inflammation and autoimmunity. Insufficient vitamin D may increase the risk of infection. Vitamin D deficiency is not the only factor linked to an elevated risk of COVID-19 infection. Recent studies have discovered a link between SARS-COV-2 infection risk and blood type. This study was aimed to examine the association of vitamin D and blood groups with the severity of COVID-19. A retrospective study was conducted on 224 confirmed COVID-19 patients, aged between 18 and 89 years old. Patients were divided into three groups (asymptomatic, moderate, and severe cases), and serum 25(OH)D concentration and blood group were analyzed for all the patients. Data of the severe cases were obtained from Souq Althalath Isolation Center, Tripoli, Libya, while moderate and asymptomatic cases were obtained from Abushusha Polyclinic and Aldahmani COVID Filtration Center, during 22nd February 2021 and 28th April 2021 and serum 25(OH)D concentration and blood group were statistically analyzed for all the patients. The percentages of males andfemales were found to be 47.3% and 52.7%, respectively. Disease severity was distributed as follows: 12.5% asymptomatic, 44.6 % moderate and 42.9% severe. Most of the severe cases had vitamin D deficiency (88.5%). Among the severely ill patients, 39.6% had blood group A and 09.4% had group O, while 22.9%, and 28.1% had blood group B and AB, respectively. In contrast, among the asymptomatic patients, only 7.1% had group A and 85.7% had group O. Overall, the difference in the distribution pattern of blood group in the three severity categories was highly significant (p < 0.001). The prevalence of Rh positivity among asymptomatic, moderate and severe cases was 78.6%, 76.0%, and 60.4%, respectively. This study concludes that insufficient vitamin D levels might influence the severity of COVID-19. COVID-19 patients with blood group A and those who are Rh-positive could be more vulnerable to developing COVID-19 severity

Fingerprint Patterns in Relation to Gender and Blood Group among Students of Delta State University; Abraka; Nigeria

Introduction: Fingerprint patterns are genotypically determined and remain unchanged from birth till death. Purpose of the study: The purpose of this study was to determine fingerprint patterns in relation to gender and blood group among students of Delta state University; Abraka; Nigeria. Materials and Methods: A total of 490 subjects; aged 17-30 years were drawn using the systematic random sampling technique. The blood group of each subject was obtained from the records in the medical laboratory register of the Health Centre of the University. Results: Fingerprints of each subject were obtained using endorsing ink and plain white paper. Female had higher percentage of loop and whorl while male had higher percentage of arch. There was no significant association between gender and finger print patterns. Within the respective ABO blood groups; loop had higher percentages compared to arch and whorl. There was no significant association between finger print patterns and ABO blood group. Within the respective Rhesus blood groups; loop had higher percentages compared to arch and whorl. There was significant association between finger print patterns and Rhesus blood group. Within the respective ABO-Rhesus blood groups; loop had higher percentages compared to arch and whorl; except in blood group O negative where whorl has higher percentage. There was significant association between finger print patterns and ABO-Rhesus blood group. Conclusion: The study showed that fingerprints; gender and ABO blood groups can only be used independently to identify an individual

The bactericidal Effect of Normal Human Serum Samples from Various Blood Groups against Local Isolates of Staphloccus aureus

"The sensitivity of staphylococcus aureus isolated in Ekpoma; Edo State; Nigeria; to the bactericidal activity of normal human sera from different blood groups (""A""; ""B""; ""AB""; ""O"") was determined using the microtitre plate method. Results obtained revealed that S. aureus was sensitive to pooled serum samples of blood groups ""B""; ""AB""; and ""O""; each accounting for 60.7 per cent; 50.5 per cent and 53.5 per cent respectively; but resistant to blood group ""A"" with a sensitivity value of 43.3 per cent. This finding which is of clinical importance shows the differences of serum batctericidal activity of normal human sera from different blood group against S. aureus."

"Hyperlipidemia in ""A"" blood group African subjects"

"Atherosclerosis is known to be related to hypercholesterolemia and ""ABO"" blood group in non African adults. This study was undertaken to determine if such a correlation between high lipid fractions and ABO blood groups also exists in African population. Two hundred and two subjects were used in this study: 36.5 per cent of them belonged to the A blood group.; 14.8 per cent to the B blood group; 2 per to the AB blood group and 46.7 per cent to the O blood group. Blood group A subjects were found to be having high total cholesterol and ApoB level and a slight increase of LDL.C Level. Analysis of the variance showed that the cholesterol level of blood group A persons was significantly different from blood group B. ApoB level of blood group A subjects was significantly different from blood B or O. When separated into two sexes; there was no significant difference between the cholestrerol level of A blood group female and male; and between their ApoB level. Elevated level of cholesterol associated in blood group A persons with high ApoB level and high ApoB/ApoA1 ratio over 0.65 enable the authors to conclude that these persons belonged to a high cardiovascular risk group; and this disease could be prevented by an early diet management"

Evaluation of the population - Genetics of Haemoglobin(s) in a rural population of Borno State

Laboratory studies were carried out on the blood samples of 2000 respondents drawn from thirty-two (32) indigenous ethnic groups in Konduga Local Government Area of Borno State; Nigeria. Of these respondents; 753 were females (37.65) and 1247 were males (62.53). The result of study showed haemoglobin electrophoretic patterns AA 79.50(1590); AS 20.10(402 and SS 0.40(8). The incidence of Hb. AS and Hb. SS vary significantly from the results observed in similar studies in Garki; Kano (1) (28.90respectively) and Ibadan (Hb. AS 24). It also significantly varies from the national average reference (2) (AA 651; AS 25; SS 2)