Mature Solid Teratoma of the Retroperitoneum Presenting as Sigmoid Colon Polyp with Lower Gastrointestinal Bleeding: A Case Report

Mature colonic teratomas are rare tumors and no case, to the best of our knowledge, has been reported from the African continent. In addition, some pedunculated teratomas in the colon have been treated by endoscopic polypectomy and classified as primary teratoma of the colon. We report a case of a distinct intra sigmoid pedunculated teratoma originating from the retroperitoneum of a 4-year-old African girl and we highlight the potential for misclassification of primary origin of endoscopically removed polypoid teratomas in the colon. CASE PRESENTATION: A 4-year-old black African female child who presented with abdominal pain and hematochezia. On clinical assessment, she was found to be anaemic and to have a sigmoid colon mass. At surgery, there was a mobile mass within the lumen of sigmoid colon and the mass was fixed to the retroperitoneum by a stalk of tissue. Pathologist's review of the resected sigmoid segment showed a pedunculated intra-sigmoid mass with the stalk traversing the wall of the colon. The mass was histologically proven a mature solid teratoma. CONCLUSION: This, to the best of our knowledge, is the first report of intra sigmoid teratoma from the African continent. It highlights the potential for misclassification of endoscopically resected colonic teratomas

Testicular tumours in prepubertal children: about eight cases

Background: To analyze the spectrum of testicular tumors in prepubertal children and the therapeutic resultants in an unselected population. Materials and Methods: Our hospital database was analyzed for testicular tumors from January 1995 to December 2010 concerning clinical presentation; treatment and therapeutic results. Results: Eight patients were operated on because of testicular tumors. In six cases (75) the tumor was benign: benign teratoma (four cases); epidermoid cyst (one case) and immature teratoma (one case). Two patients (25) had a malignant tumour: yolk-sac tumour (two cases). All this children underwent surgery. Radical inguinal orchidectomy was performed in six cases and conservative surgery was performed in two cases. One patient has received adjuvant chemotherapy. Follow-up was uneventfully three years after primary surgery. Conclusion: In prepubertal children; most testicular tumours are benign. If tumour markers were negative testis-preserving surgery can be proposed; complete excision of the tumour should be ascertained. In the case of testicular teratoma; the possibility of contralateral tumour should be considered in the follow-up

Pattern and Outcome of Childhood Teratoma: a 10-Year Review

Background: Teratomas are neoplasms which originate from pluripotent stem cells. They are composed of a wide variety of tissues foreign to the organ or anatomic site in which they arose. This study sought to determine the clinical manifestations and outcome of treatment of childhood teratomas. Method: A retrospective analysis of the case files of children treated for teratoma at the University of Benin Teaching Hospital Benin City; Nigeria between January 1999 and December 2008 was done. Results: Fifty-three children aged between 5 days and 16 years; comprising 15 males and 38 females with male:female ratio of 2:5 were treated for teratoma; gonadal 27(50.9) and extragonadal 26 (49.1). Ovarian; 23 (43.4) and sacrococcygeal; 17 (32.1) sites were frequently involved. Other sites included testicular; 4 (7.5); retroperitoneal; 4 (7.5) and renal; 2 (3.8); while posterior mediastinal; cervical and breast involvement were 1 (1.9) each. Despite late presentation; no frankly malignant primary teratoma was diagnosed. Benign cystic teratomas with malignant elements comprising yolk sac tumour and immature neuroepithelial elements (mixed germ cells tumour) were the major histological types. Complete tumour resection that included total coccygectomy; oophorectomy and orchidectomy; plus combination chemotherapy using vincristine; actinomycin; and cyclophosphamide was curative in 25 (47.2) children. Eighteen (34) cases of recurrence were all malignant. They presented very late with rapid disease progression that resulted in 10 (18.8) deaths during the five years of follow-up. Conclusion: Although all primary teratoma were benign; recurrent malignant tumours with rapid progression to carcinomatosis; multiple organs failure and deaths were common in childhood teratoma. We advocate close follow-up of all children with teratoma to detect and commence early treatment

Teratome intra pulmonaire. A propos d'un cas

La localisation intra pulmonaire des teratomes est inhabituelle. La forme maligne de cette pathologie constitue une eventualite rare et particuliere des cancers du poumon. Nous rapportons un cas de teratome intra pulmonaire de forme maligne chez une femme de 52 ans. Notre objectif; a travers ce cas; est de faire connaitre cette pathologie et de realiser une revue de litterature afin de soulever les aspects clinique; therapeutique et evolutif

Les teratomes sacro-coccygiens : etude retrospective a propos de 24 cas colliges dans le service de Chirurgie pediatrique du CHU de Treichville

Celle etude retrospective portant sur 24 dossiers de patients; a pour but d'analyser les resultats de la prise en charge des teratomes sacro-coccygiens au CHU de Treichville.De 1983 a 2003; nous avons traite 24 patients atteints de teratomes sacra-coccygiens.Resultat: il s'agissait de 20 filles et de 04 garcons. L'age des enfants variait entre I jour et 2 ans 6 mois.La tumeur avait un developpement endopelvien dans 02 cas et developpement exopelvien dans 21 cas soit 21;3pour cent.Selon la classification d'Altman; nous avons observe:*15 cas de type I;*4 casdeType lI*3 cas de type III;*2 cas de type IV.Le dosage du taux d'Alpha foto-proteine a ete faite chez tous nos patients avant et apres l'intervention. Le traitement a consiste en une exerese chirurgicale de la tumeur: 21 enfants ont beneficie d'une exerese chirurgicale. 01 enfant est sorti sans avis medical.La chimiotherapie notamment le protocole VAC a encadre la chirurgie dans les cas de teratomes avec metastase; Les enfants ont ete suivis avec un recul moyen de 10;5 ans.*15 enfants avaient un taux d'Alpha foto-proteine eleve;*01 seul enfant avait un teratome malin avec des metastases pulmonaire qui ont necessite une chimiotherapie pre-operatoire;* 02 types de complications ont ete observes;*03 cas d'infections parietales avec lachage de suture et 01 cas de stenose anale ayant necessite des dilatations anales.Le dosage du taux d'Alpha foeto-proteine post-operatoire a permis de noter les resultats suivants:-a 1 mois; taux normal dans 9 cas;-a 2 mois; taux normal chez tous les enfants suivis : 21 cas.Le taux de recidive est nul.Conclusion: Le TSC est une tumeur congenitale benigne dans la majorite des cas. Il a un potentiel de degenerescence maligne eleve; diagnostique et traite precocement; le pronostic est bon