Coumarins with antiviral and cytotoxic activity from Egyptian panunculus asiaticus L

Three coumarins were isolated from the CHCl3 extract of the aerial parts of Ranunculus asiaticus L. [Ranunculaceae]. They were identified as aesculetin dimethyl ether [6,7-dimethoxy-coumarin] [I], isoscopoietin [II] and scopoietin [III], based on their spectral and physical data. The cytotoxic and antiviral activities of I and III were evaluated

Constituents of convolvulus lanatus vahl with antiviral and cytotoxic activity

Three coumarins; namely, scopoietin [I], umbelliferone [II] and esculetin [III] as well as caffeic acid [IV] and a flavone glycoside, isoquercitrin [V] were isolated from EtOAc extract of the aerial parts of Convolvulus lanatus Vahl. [Convolvulaceae]. The identification was based on spectral and physical data of the isolated compounds. The cytotoxic and antiviral activities of compounds I, IV and V were evaluated

Antimicrobial evaluation of extracts from some Yemeni plants

Extracts of 23 Yemeni higher plants were screened for their antibacterial and antifungal activity by the agar diffusion technique. The extracts that exhibited the highest activities were further evaluated by measuring their minimum inhibitory concentrations [MICs]. Three organisms; namely, Staphylococcus aureus [ATTC 29523], Escherichia coli [HP 101] and C and ida albicans [NCTC 2708], were used

Cytotoxic antiviral activities of marine plants and lower animals from Yemen

Ethanolic extracts of 31 marine plants and lower marine animals, collected from different areas on the coasts of Yemen, were screened for cytotoxic and antiviral activities. Cytotoxic activity was compared in a normal and oncogenically transformed mammalian cell line, and in a proliferating and non-proliferating non-transformed mammalian cell line. Two out of 31 extracts exhibited potent cytotoxic activity, arbitrarily defined as an IC50 [defined as the concentration of extract which gives approximately 50% inhibition of cell proliferation] of 10 mug/ml or less against NIH3T3 cells. Antiviral assays were performed against a DNA virus, herpes simplex type 1, and an RNA virus, vesicular stomatitis virus. Only one extract showed antiviral activity against herpes simplex type 1

Effect of hormone sequential supplement on plant regeneration by somatic embryogenesis from hypocotyl cultures of foeniculum vularge

Callus was obtained from seedling hypocotyls on an agar solidified Murashige revised tobacco [MS] medium containing 1 mg/L. 2,4-dichlorophenoxyacetic acid [2,4-D 1]. Suspension cultures were initiated from callus using a series of the following liquid media: 2,4-dichlorophenoxyacetic acid 0.5 mg/L [2,4-D 0.5], 2,4- dichlorophenoxyacetic acid 0 mg/L [2,4-D 0], benzyladenine 0.5 mg/L [BA 0.5], benzyladenine 1 mg/L [BA 1] and benzyladenine 5 mg/L [BA 5]. Compact cells of meristematic nodules were obtained at periphery of callus aggregates that developed into globular, heart and torpedo stages of somatic embryos. Plant regeneration has been achieved by culturing the embryos on solid MS medium deprived of growth regulators