Central Photoreceptor Viability and Prediction of Visual Outcome in Patients with Idiopathic Macular Holes

PURPOSE: To identify the correlation between preoperative optical coherence tomography (OCT) features and postoperative visual outcomes in eyes with idiopathic macular holes (MHs). METHODS: Data from 55 eyes with idiopathic MHs which had been sealed by vitrectomy were retrospectively reviewed. Correlation analysis was conducted between postoperative visual acuity (V(postop), logarithm of the minimum angle of resolution [logMAR]) and preoperative factors, including four OCT parameters: the anticipated length (A) devoid of photoreceptors after hole closure, MH height (B), MH size (C), and the grading (D) of the viability of detached photoreceptors. Additionally, the formula for the prediction of visual outcome was deduced. RESULTS: V(postop) was determined to be significantly correlated with the preoperative visual acuity (V(preop)) and OCT parameters A, C, and D (p<0.001). Based on the correlation, the formula for the prediction of V(postop) was derived from the most accurate regression analysis: V(postop)=0.248xV(preop)+1.1x10(-6)xA(2)-0.121xD+0.19. CONCLUSIONS: The length and viability of detached photoreceptors are significant preoperative OCT features for predicting visual prognosis. This suggests that, regardless of the MH size and symptom duration, active surgical intervention should be encouraged, particularly if the MH exhibits good viability in the detached photoreceptor layer.

The Surgical Outcome of Partially Accommodative Esotropia with a Large Angle of Deviation

PURPOSE: To investigate the surgical outcome of patients with partially accommodative esotropia with a large angle of deviation. METHODS: Twenty-one patients with partially accommodative esotropia that had angles of deviation of at least 40 prism diopters without correction, were retrospectively studied. They underwent standard surgery, for which the amount of recession was based on the average of the distance and near deviation with correction. The angle of deviation were evaluated at postoperative 3 months and at the last follow-up, and the Titmus test and Worth 4-dot test were performed after surgery. RESULTS: The mean angle of deviation without correction at the first examination was 57.0PD, and the mean age of correction with glasses was 2.6 years. The mean angle of deviation with correction was 31.4PD. The mean age at surgery was 4.4 years. The mean follow-up period was 5.4 years. At 3 months postoperatively, 66.7%, 28.6%, and 4.8% of patients showed acceptable correction, undercorrection, and overcorrection, respectively. At the last visit, undercorrection decreased while overcorrection increased (66.7%, 23.8%, 9.5%). Titmus stereotest showed in positive results with more than 800 seconds of arc in 9 of 16 patients. A Worth 4-dot test resulted in a fusion response at far or at near in 4 of 17 patients. CONCLUSIONS: In partially accommodative esotropia with a large angle of deviation (at least 40PD without correction), the results of conventional surgery were relatively fair, while the prognosis of sensory function was poor.

Monocanalicular Silicone Stent Insertion in Children with Nasolacrimal Duct Obstruction

PURPOSE: To determine the efficacy of Mini Monoka silicone stent insertion in treating nasolacrimal duct obstruction in children. METHODS: In 67 eyes of 61 children with nasolacrimal duct obstruction, the Mini Monoka silicone stent was inserted after probing under general anesthesia. The duration of epiphora or discharge, the age at the time of surgery, and probing history were recorded. The surgical results and postoperative complications were analyzed for the cases herein of Mini Monoka silicone stent insertion. RESULTS: The technical success rate of Mini Monoka silicone stent insertion was 91% in children with nasolacrimal duct obstruction, and the success rate for children without probing history was much higher than for those with probing history (81.5 : 97.5%, p=0.035). Postoperatively, the symptoms were resolved in 54 of 61 eyes (88.5%). The duration of preoperative symptoms was shorter in the successful group than in the failed group (15.9+/-7.1 : 21.9+/-8.8 months, p=0.044). Mini Monoka silicone tube was easily removed at 5.6 months after insertion in the clinic. Dacryocystitis was found to be a complication in two eyes yet was resolved without recurrence. Of the seven eyes with spontaneous extrusion of the stent, symptoms subsided in five eyes. CONCLUSIONS: Mini Monoka silicone stent insertion is an effective and relatively easy method, with a low risk of complication, to treatment children with nasolacrimal duct obstruction.

Monocanalicular Silicone Stent Insertion in Children with Nasolacrimal Duct Obstruction

PURPOSE: To determine the efficacy of Mini Monoka silicone stent insertion in treating nasolacrimal duct obstruction in children. METHODS: In 67 eyes of 61 children with nasolacrimal duct obstruction, the Mini Monoka silicone stent was inserted after probing under general anesthesia. The duration of epiphora or discharge, the age at the time of surgery, and probing history were recorded. The surgical results and postoperative complications were analyzed for the cases herein of Mini Monoka silicone stent insertion. RESULTS: The technical success rate of Mini Monoka silicone stent insertion was 91% in children with nasolacrimal duct obstruction, and the success rate for children without probing history was much higher than for those with probing history (81.5 : 97.5%, p=0.035). Postoperatively, the symptoms were resolved in 54 of 61 eyes (88.5%). The duration of preoperative symptoms was shorter in the successful group than in the failed group (15.9+/-7.1 : 21.9+/-8.8 months, p=0.044). Mini Monoka silicone tube was easily removed at 5.6 months after insertion in the clinic. Dacryocystitis was found to be a complication in two eyes yet was resolved without recurrence. Of the seven eyes with spontaneous extrusion of the stent, symptoms subsided in five eyes. CONCLUSIONS: Mini Monoka silicone stent insertion is an effective and relatively easy method, with a low risk of complication, to treatment children with nasolacrimal duct obstruction.

Needle Revision with and without Mitomycin C for the Teatment of Failed Filtering Blebs after Trabeculectomy

PURPOSE: To evaluate the effects of needle revision (NR) with and without mitomycin C (MMC) for failed filtering blebs after trabeculectomy, and to identify risk factors for failure. METHODS: Thirty-one eyes whose intraocular pressure (IOP) did not decrease after cutting of scleral flap sutures were recruited. NR was performed with a 26-gauge needle under a slit-lamp. Immediately following NR, 15 eyes received subconjunctival injection of 0.002 mg (0.02 mg/ml) MMC at the adjacent conjunctiva. RESULTS: First NR was done at 1.3+/-1.2 months (range, 0.2~6.5 months) after trabeculectomy, and a mean of 1.6+/-1.6 NRs per patient were done. The follow-up period was 24.4+/-20.4 months (range, 6.0~87.4 months) after the last NR. Pre-NR mean IOP was 27.9+/-11.6 mm Hg and post-NR final IOP was 18.8+/-13.0 mm Hg (p=0.005). The success rate, defined as IOP 25 mm Hg showed a higher failure rate, though with no statistical significance (p=0.141 and p=0.173, respectively). CONCLUSIONS: NR followed by subconjunctival injection of MMC is an effective and safe method for the treatment of the failed filtering blebs after trabeculectomy. Trabeculectomy without adjunctive MMC and pre-NR IOP higher than 25 mmHg were risk factors for failure of NR.

The Effect of Myectomy on the Grading of Overaction of the Inferior Oblique Muscle

PURPOSE: This study assesses the surgical results of inferior oblique myectomy on the degree of overaction in patients with overaction greater than +2 of the inferior oblique muscle. METHODS: Seventy eyes of 54 patients underwent an inferior oblique myectomy and at least 6 months of follow-up. Patients with contracture of the superior rectus muscle or dissociated vertical deviation were excluded. The chief complaints, preoperative and postoperative degrees of overaction of the inferior oblique muscle, the angle of hypertropia, and head tilt were analyzed. RESULTS: Deviation of the eyeball (38.9%) and head tilt (25.9%) were the most common complaints. Overall, the success rate was 91.4%, and the likelihood of success decreased with increasing severity of overaction of the inferior oblique muscle. The angle of hypertropia reduced from 11.9 (Prism diopters, PD) preoperatively to 2.2PD postoperatively (p=0.000). Preoperative head tilting was seen in 20 patients (37%) and all saw postoperative improvement. CONCLUSIONS: Inferior oblique myectomy is effective in treating the overaction of the inferior oblique muscle without contracture of the superior rectus muscle or dissociated vertical deviation, especially in patients with greater than +2 overaction of the inferior oblique muscle.

Clinical Characteristics of Strabismic Children with A History of Pseudoesotropia

PURPOSE: The epicanthal fold in Korean children is a common cause of pseudoesotropia. Therefore, the present study was undertaken to evaluate the clinical characteristics of strabismus in children diagnosed with pseudoesotropia. METHODS: We reviewed the charts of children diagnosed with strabismus from February 2004 to January 2005. Strabismic children with a history of pseudoesotropia were included in this study. We recorded the age and chief complaints at the time of pseudoesotropia diagnosis as well as the type of strabismus, the visual acuity, chief complaints, and refractive error at the time of strabismus diagnosis. RESULTS: One hundred and two of 734 children with strabismus (13.9%) had a history of pseudoesotropia. The mean age at the time of pseudoesotropia diagnosis was 2.9 years. The mean age at the time of strabismus diagnosis was 4.4 years. The type of strabismus was exotropia in 58 (56.9%) and esotropia in 39 (38.2%) cases. Refractive accommodative esotropia was seen in 89.7% of esotropia cases and the basic type was seen in 86.2% of exotropia cases. The concurrence rate between chief complaints of pseudoesotropia and the type of strabismus diagnosed was lower in exotropia than in esotropia. There was hyperopia in all the esotropia cases, and the distribution of refractive error was variable in exotropia. The frequency of amblyopia was 19.6%. CONCLUSIONS: The incidence of strabismus is high in the case of children diagnosed with pseodoesotropia. Therefore, regular examinations for strabismus, refractive error and amblyopia may be necessary.

A Case of cutaneous Metastasis Originating from Prostatic Carcinoma / 대한피부과학회지

Cutaneous metastasis from internal malignacy is recognized but infrequently occuring manifestation. The prostatic carcinoma rarely acts as a primary source for cutaneous metastasis. We report a case of cutaneous metstasis from prostatic carcinoma. A 82-year-old male presents multiple painless erythematous nodules on suprapubic area, having an episode of surgical removal of prostate carcinoma two years ago. Histologic finding shows atypical anaplastic cell infiltration at the dermis and subcutaneous tissue, forming dermal tumor island, and have features similar to primary prostatic carcinoma. Immunohistochemical staining for prostate specific antigen shows positive reaction within cells, can assist in localization of the metatatic adenocarcinoma to a prostate origin.

A Case of cutaneous Metastasis Originating from Prostatic Carcinoma / 대한피부과학회지

Cutaneous metastasis from internal malignacy is recognized but infrequently occuring manifestation. The prostatic carcinoma rarely acts as a primary source for cutaneous metastasis. We report a case of cutaneous metstasis from prostatic carcinoma. A 82-year-old male presents multiple painless erythematous nodules on suprapubic area, having an episode of surgical removal of prostate carcinoma two years ago. Histologic finding shows atypical anaplastic cell infiltration at the dermis and subcutaneous tissue, forming dermal tumor island, and have features similar to primary prostatic carcinoma. Immunohistochemical staining for prostate specific antigen shows positive reaction within cells, can assist in localization of the metatatic adenocarcinoma to a prostate origin.