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1.
Acta gastroenterol. latinoam ; 33(1): 13-21, 2003. tab
Article in Spanish | LILACS | ID: lil-356925

ABSTRACT

The role of Helicobacter pylori (Hp) in Non Ulcer Dyspepsia (NUD) has been a controversial issue. OBJECTIVES: 1) To determine the frequency of Upper Gastrointestinal Endoscopy (UGE) in patients suffering NUD in whom endoscopy was indicated in our Service, 2) To determine the prevalence of infection by Hp in patients with NUD in whom endoscopy was done, 3) To find an association of clinical and historical facts among patients with and without Hp infection. POPULATION AND SAMPLE: 91 consecutive patients, free of esophageal or gastro-intestinal organic disease by endoscopic criteria from a total of 132, in a period of six months. 47 men (X age: 50.4 years, SE 2.6, SD 17.3) and 44 women (X age 49.7 years, SE 2.5, SD 16.8), Levene's Test p = 0.91. Descriptive, comparative and correlation, transverse simple-blind. METHODS: 1) two endoscopic biopsies for Hp (antrum and corpus), Rapid Hp Urease Test (modified Christensen protocol) with immediate and 6-hours later readings; 2) two samples for histopathologic diagnosis of Hp (antrum and corpus) with H&E, Giemsa or Warthin-Starring. STATISTICS: Levene Test for homogeneity of variance, descriptive statistic tests, ANOVA, chisquare, contingency coefficient, Pearson's r, Run Tests. Alpha level = 0.05. RESULTS: 91 out 132 patients were included (69.9 per cent). Prevalence was greater in men (p = 0.04). Run Tests for variables between 0.34 and 0.76, 45 patients were positives (+) for one or two methods (49.5 per cent). There were significative differences between the means for variable age for the groups (+) and (-) at the moment of the study (+, mean age 45 years old, SE 2.4; negative tests, mean age 55 years old, SE 2.5, p = 0.005). Wide data dispersion (Coefficient of Pearson = 34.5 per cent). There was association between age symptoms onset and positive tests (mean 40.4 years old, SE 2.6, Coefficient of Pearson 43 per cent) and negative tests (mean 48.9 years old, SE 2.6, Coefficient of Pearson 36 per cent) (p = 0.02). There were also association between age and + tests (p = 0.005). Non statistically significant differences were found between time of evolution of symptoms (p = 0.49), prevalence between sexes of symptoms (although nearly significant, p = 0.06), presence of unespecific pain (p = 0.16), ulcer-like pain (p = 0.46), plenty sensation, distension, satiety (p = 0.64) and differences by sex and age in symptoms (p = 0.55).


Subject(s)
Adolescent , Humans , Male , Female , Adult , Middle Aged , Dyspepsia , Helicobacter Infections , Helicobacter pylori , Aged, 80 and over , Cross-Sectional Studies , Gastroscopy
2.
Acta gastroenterol. latinoam ; 33(2): 79-92, 2003. tab
Article in Spanish | LILACS | ID: lil-420386

ABSTRACT

OBJECTIVES: 1) To determine differences between sexes; 2) To determine differences by sex and age groups in symptom onset, time of evolution, clinical forms and probable associated causes. POPULATION AND SAMPLE: 83 consecutive patients with diagnosed PCP (X age = 50.9 SE 2.21). 25 males (30.1% x 51.2 years-old, SE 4.1) and 58 females (69.9%, X 50.8 years-old, SE 2.2). Patients with organic colon-rectum pathology (with the exception of hemorrhoidal pathology, proctologic surgery and active anus fissure) had been excluded. METHODS: ...


Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Middle Aged , Constipation/etiology , Pelvic Floor/physiopathology , Stress, Physiological , Age Distribution , Age of Onset , Argentina/epidemiology , Constipation/diagnosis , Constipation/epidemiology , Prevalence , Prospective Studies , Sex Distribution , Single-Blind Method
3.
Acta gastroenterol. latinoam ; 30(3): 159-64, jul. 2000. tab
Article in Spanish | LILACS | ID: lil-269919

ABSTRACT

After being ingested, food and liquids suffer a thermal regulation process, which adapts them immediately to the body temperature by means of the mucosa diffusion. We have not found bibliographical information about this matter yet. OBJECTIVES: 1) To describe the reaction of the oropharynx area and the esophagus by heat and coldness. 2) To compare both areas reaction. STUDY POPULATIONS: Six patients (three men, three women, Age: mean 42 years old, SD 11.8), healthy individuals without both gastrointestinal and systemic disease that could after microcirculation. MATERIALS & METHODS: Temperature measurement of liquid at mouth entrance and at 24 cm and 38 cm from dentary superior arcade using two thermocouples. Deglution of 40 ml of hot water (X 60 degrees C at entrance) or cold water (X 4 degrees C) in two draughts. Temperature measurement at both thermocouples at the end of deglution (time = 0 (zero)) and every 10 seconds. Random sequences every 30 minutes. RESULTS: Using water at 60 degrees C, the temperature descended to 42 degrees C in the distal end. The oropharynx region dissipated 45 per cent of the initial temperature while the esophagus completed the other 55 per cent.The esophagus itself dissipated 65.6 per cent of the 12.2 degrees C in time = 0 (zero). After 40 seconds the temperature reached the normal body temperature. In the case of the iced water (4 degrees C), the total work consisted on increasing temperature 33.6 degrees C to the normal corporal temperature. The 68.45 per cent of the difference between the initial and the final temperature was obtained by the oropharynx region and the rest by the esophagus. In time = 0 (zero) the temperature increased up to 30 degrees C and the esophagus only contributed with 28.3 per cent of the total work. The normal corporal temperature was reached after 40 seconds. It was observed a significant difference in the heating capacity between the oropharynx region and esophagus (p > 0.001)...


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Body Temperature Regulation , Esophagus/blood supply , Oropharynx/blood supply , Vasodilation , Cold Temperature , Heating , Prospective Studies
4.
Acta gastroenterol. latinoam ; 30(1): 15-25, mar. 2000. tab
Article in Spanish | LILACS | ID: lil-262233

ABSTRACT

Objetivos: 1) Describir y comparar las características históricas del sintoma de pirosis con prueba de perfusión ácida positiva en el grupo total y según sexos; 2) describir los resultados de los estudios (clearance ácido estánder, número de episodios de reflujo en tiempos cortos de observación, tiempo de aparición de la pirosis durante la perfusión ácida, tiempo de desapacición del síntoma y pH del esófago en el momento de la desaparición); comparación por sexos; 3) comparar las diferencias de depuraniones estándar y de episodios de reflujo entre controles y pacientes; 4) correlacionar de factores condicionantes; 5) realizar las mismas evaluaciones descriptivas y comparativas en los subgrupos con hernia hiatal (H.H.) y sin ella. Trabajo prospectivo, descriptivo y comparativo, experimental, longitudinal, ciego simple, con muestra de control. Población y muestra: 15 pacientes de control (9 hombres, mujeres) y 50 pacientes con pirosis (23 hombres, 27 mujeres). Mayores de 18 años. Con H.H. o sin ella. Equiparables (diderencias en edad y sexo, p=NS). Consecutivos. Material y metodologia: Registro de datos históricos, endoscopia alta, 3 (tres) biopsias como mínimo, número de episodios de reflujo en 30 minutos de observación, clearance ácido estánder, medición de tiempo de perfusión, tiempo de desaparición del síntoma evocado y pH en que desaparece el síntoma...


Subject(s)
Male , Female , Adult , Middle Aged , Esophagus/physiopathology , Heartburn/etiology , Hydrogen-Ion Concentration , Hyperalgesia/diagnosis , Aged, 80 and over , Analysis of Variance , Biopsy , Case-Control Studies , Endoscopy, Gastrointestinal , Gastric Acidity Determination , Gastroesophageal Reflux/complications , Gastroesophageal Reflux/physiopathology , Heartburn/physiopathology , Hernia, Hiatal/complications , Hydrogen-Ion Concentration , Hyperalgesia/physiopathology , Longitudinal Studies , Prospective Studies , Severity of Illness Index , Single-Blind Method , Time Factors
5.
Acta gastroenterol. latinoam ; 29(3): 125-33, 1999.
Article in Spanish | LILACS | ID: lil-245903

ABSTRACT

La relación médico-paciente representa un vínculo particular que transciende lo formol y se proyecta en el tiempo, el espacio y la emocionalidad. Se produce en un contexto cultural, social, psicológico, científico y técnico, condicionado por variables locales, regionales, nacionales y supranacionales y en el que la entidad, la estraficación social, las creencias religiosas y los valores éticos y morales juegan un rol pivotal. Los avances en los últimos 40 años han mostrado una curva exponencial últimos 40 años han mostrado una curva exponencial de la mano de profundos cambios que abarcan desde lo filosófico hasta lo estrictamente técnico. Ello ha afectado profundamente la relación entre el médico y el paciente. Las consecuencias han sido desafortunadas tanto para el médico como, y en particular, para el paciente. Estos cambios aparecem o se intensifican significativamente en el período de postguerra de la Segunda Guerra Mundial, y la tecnificación es el aspecto más aparente. Se exteriorizan por replanteos a nivel filosófico, desarrollo del liberalismo y neo-liberalismo económicos, replanteo en el concepto de ciencia, priorización del desarrollo tecnológico, cambios en las escalas de valores ético-morales y cambios en las hegemonías del poder político y económico. Los grandes relato de la filosofía han justificado los cambios sociales. El fin de los metadiscursos modernos (iluminismo, idealismo y marxismo) ha dado lugar al discurso liberal y, finalmente, al neoliberalismo. El "saber" ha sido afectado tanto en la investigación como en la enseñanza, y el nuevo metadiscurso pasa ahora por la performance. La conjugación orgánica de la técnica con la ganancia precede a su unión con la ciencia. La retirada del Estado en muchos países de los grandes problemas sociales, la globalización y la concentración del capital han redefinido el poder. Ni el paciente ni la medicina escapan a esta nueva realidad. La resultante final son generaciones de médicos bastante bien informados pero incapaces de enfrentar y resolver las problemáticas mínimas de un paciente, con el agravante de sentirse frustrados y resentidos. Se piensa y actúa a través de la técnica...


Subject(s)
Humans , History, 20th Century , Physician-Patient Relations
6.
Acta gastroenterol. latinoam ; 27(1): 7-14, mar. 1997.
Article in Spanish | LILACS | ID: lil-196657

ABSTRACT

The aim to study the alterations in mechanosensitivity gastric emptying, and electrogastrography (E.G.G.) in a population of patients suffering from N.O.D. eighteen controls (9 males, 9 females, mean age 49.33 years old0.01). Twenty porcent of controls showed isolated tachygastria, but dominant frecuencies never were higher than 6 c.p.m and never last more than 8 percent of the total recording time. Sixty eight point seventy five porcent of N.O.D. showed arrhytmias, 48 percent of tachygastrias were in the range 30-60 percent of total recording time. No differences in gastric emptying between patient presenting pain with=<700ml. and <700ml. of balloon inflation were seen. Patients with sensorial treshold=<700ml. showeed less frequent tachigastria (0.01

Subject(s)
Adult , Middle Aged , Female , Humans , Adolescent , Dyspepsia/physiopathology , Electromyography/methods , Gastric Emptying/physiology , Gastrointestinal Motility/physiology , Stomach Volvulus , Stomach/physiopathology , Aged, 80 and over , Prospective Studies
7.
Acta gastroenterol. latinoam ; 26(3): 143-7, 1996. tab, graf
Article in Spanish | LILACS | ID: lil-186202

ABSTRACT

Patients with non ulcer dyspepsia (NUD) and lowered mechano sensitivity tresholds in stomach may have lowered mechano sensitivity treholds in oesophagus also. The aim was to check this hypothesis. Methods: 39 patients with NUD (11 men and 24 women, mean age 57 years, SEM 3.72, range 17-86) and 20 controls (10 men, 10 women, mean age 49.3 years, SEM 3.72, range (31-66) were studied. Organis diseases were discarded. Gastric mechano sensitivity was studied with a latex ballon of low compliance, 8 cm lenght, conected to a manometer. Ballon was inflated "in ramp"at 10 ml/sec. and "first sensation", disconfort", and "pain" were registered. At 900 ml inflation was stopped if pain was not evoked. Oesophageal mechano sensitivity was studied with another latex ballon of low compliance which, after inflated with 15 ml. of air, was 3.5 cm. in diameter. Esophageal ballon was inflated "in ramp" (1 ml/sec) up 15 ml. and deflated in 2 cm step from 36 to 22 cm from SDA. Infaltion was stopped whrn symptoms (pain or disconfort were evoked. Oesophageal acid perfusion test was performed. Results: 83.4 per cent of controls completed up 700 ml. of gastric distension vs. 35.9 per cent of patients with NUD (p>0.001). No significatives differences in intra-ballon pressure slope were observed between both groups. 79.2 per cent of NUD patients had chest pain with oesophageal ballon distension =<7 ml. vs. 5 per cent in controls (p>0.001). Mean volumes were 7.03 ml. (NUD) and 11.9 per cent (controls) (p=0.001). 63 per cent of dyspeptic patients with lowered gastric sensitivity tresholds (< 700 ml) had oesophagic symptoms with inflation volumes =< 7 ml. There was a positive correlation is stomach and oesophageal mechano sensiticities variations (r= 0.75 +/-0.58, p>0.01). Whem analyzed with that results, oesophageal acid perfusion test showed 38.5 per cent of "mixed sensitivities" (both mechano-and chemo-), 30.7 per cent of "mechano sensorials" (negative acid test, positive ballon test), and 10.3 per cent of schemo sensorials" (positive acid test only). In 20.5 per cent both tests were normal at the moment they were done. These results agreed with our previous experiences in oesophagus. Conclusions: It was concluded that a significative proportion of NUD patients had lowered tresholds for mechano stimulation of stomach and oesophagus at the time that both tests were done. Such alterations support the hypothesis that a more general mechano-sensitivity alteration in present in patients with NUD.


Subject(s)
Female , Humans , Adult , Middle Aged , Adolescent , Dyspepsia/physiopathology , Esophagus/physiopathology , Stomach/physiopathology , Aged, 80 and over , Biomechanical Phenomena , Insufflation , Manometry , Pain Measurement , Prospective Studies
8.
Acta gastroenterol. latinoam ; 25(5): 291-4, 1995. ilus
Article in Spanish | LILACS | ID: lil-164078

ABSTRACT

Se presentan dos pacientes con derrame pleural masivo asociado a cirrosis, sin evidencias clínicas de ascitis, y en el primero de los casos sin ascitis visible en la T.A.C. Se descartan otras patologías causales y se analiza su respuesta terapéutica. Se analizan los mecanismos de producción del síndrome y se postula al Neumoperitoneo como rpocedimiento diagnóstico fácil y de bajo costo.


Subject(s)
Humans , Male , Female , Middle Aged , Liver Cirrhosis/complications , Pleural Effusion/etiology , Ascites/diagnosis , Methylene Blue , Pleural Effusion/diagnosis , Pleural Effusion/pathology , Punctures , Tomography, X-Ray Computed
11.
Acta gastroenterol. latinoam ; 24(4): 219-32, 1994. tab, ilus, graf
Article in Spanish | LILACS | ID: lil-141996

ABSTRACT

Se investigó la mecano y quimio-sensibilidad del esófago en 20 sujetos control y en 73 pacientes con purisus, D.T.N.C. y la combinación simultánea de dolor y pirosis. Se utilizó la prueba de distensión de un balón hasta 15 ml., en escalas de 2 cm. desde los 38 hasta los 22 cm. de la A.D.S. Se registró el número de pacientes que respondieron, volúmenes de distensión necesarios para evocar el sintoma, sitio de aparición y propagación del mismo. Las zonas de propagación fueron ubicadas en 13 zonas frontales y 10 dorsales. Se consideró como número de respuestas a la suma de las zonas de propagación para cada nivel estimulado (9 en total). En la misma sesión se realizó la prueba de perfusión ácida y el clearance ácido de es£fago. Se consideró como prueba positivo cuando se reprodujo el síntoma espontáneo. Se realizó endoscopía previa en todos los pacintes. RESULTADOS: La prueba de balón reprodujo el síntoma dolor en el 77.5 por ciento, cifra alcanzada estimulando los 9 niveles. De haberse estimulado un solo nivel la proporción no hubiera superado el 51 por ciento. Existen zonas "mudas" con relativa frecuencia. El 66.6 por ciento respondió con volúmenes < de 7 ml. La endoscopía fue normal en todos ellos. El test de perfusión ácida reprodujo la pirosis en el 62.5 por ciento. La presencia de esofagitis determinó una tendencia a aumentar la probabilidad de prueba positiva. Los pacientes con la combinación pirosis-dolor respondieron por separado ante cada prueba en el 60 por ciento. La perfusión ácida reprodujo el D.T.N.C. en el 6 por ciento. La prueba del balón reprodujo la pirosis en el 6.1 por ciento. CONCLUSIONES: 1) La prueba del balón sería la más útil en el estudio de la mecano-sensibilidad con altos porcentajes de reproducción cuando se estimulan al menos 9 niveles. 2) el test de perfusión sería útil para investigar quimio-sensibilida. La esofagitis aumentaria la posibilidad de test positivo. 3) Los pacientes con síntomas combinados se comportarían ante los tests de provocación como una disfunción sensorial mixta . 4) Una subpoblación de pacientes mostraría comportamientos atípicos ante los tests de...


Subject(s)
Adult , Middle Aged , Humans , Male , Female , Chest Pain/etiology , Esophagus/physiopathology , Heartburn/etiology , Case-Control Studies , Gastric Balloon , Perfusion , Prospective Studies
12.
Acta gastroenterol. latinoam ; 24(1): 15-21, 1994. ilus, tab
Article in Spanish | LILACS | ID: lil-131825

ABSTRACT

El esófago es origen de varias formas de sensibilidad dolorosa. La sensorialidad sigue las leyes de la sensibilidad visceral general con algunas variantes individuales. Se estudiaron las áreas de proyección del dolor despertado por la distensión progresiva de un balón a intervalos de c cm., desde los 38 a los 22 cmn. de la A.D.S. Se registró el número de respuestas en cada una de las 13 zonas frontales y 10 dorsales en que se dividió arbitrariamente el tórax, e incluyendo al epigastrio y la base del cuello. Se consideró la primera respuesta a la distinsión, o hasta un máximo de 15 ml. de aire (diámetro del balón=3.2 cm). Se estudiaron 101 pacientes (controles y con síntomas esofágicos no orgánicos, con excepción de la esofagopatía por reflujo). Se obtuvieron 1153 respuestas en total en los 9 niveles estimulados, de las cuales el 93.8 por ciento se presentaron en las zonas frontales, y de ellas el 82.4 por ciento en las áreas mediales (epigastrio a base del cuello). No se encontraron diferencias entre los sexos. El esófago inferior fue significativamente menos sensible que el superior. El número de proyecciones hacia el tórax superior fue proporcionalmente mayor que su inversa. Se encontraron modelos individuales que resultarían útiles frente a un paciente en particular. Conclusiones: a) el esófago no es igualmente sensible a toda su extensión; b) la proyección metamérica es múltiple y predomina ampliamente en el plano frontal; c) la existencia de "zonas de gatillo" puntuales obliga a estudiar toda la extension del esófago cuando se utiliza la prueba como test diagnóstico


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Catheterization , Esophagus , Pain/etiology , Chest Pain/etiology , Insufflation , Mechanoreceptors , Prospective Studies
14.
Acta gastroenterol. latinoam ; 24(4): 219-32, 1994.
Article in Spanish | LILACS-Express | LILACS, BINACIS | ID: biblio-1157273

ABSTRACT

Mechano--and chemo--sensitivity were studied in 20 normal control patients and 73 patients suffering from pirosis, chest pain or both symptoms. Upper endoscopy, balloon and acid perfussion tests were performed. Balloon was inflated up to 15 ml. and deflated, in 2 cm. steps from 38 to 22 cm. from S.D.A. The number of patients with response, volume of balloon distension that evoked symptoms, place and irradiation of pain or discomfort were registered and plotted on 13 frontal and 10 dorsal zones. The total number of areas involved in pain irradiation was considered as [quot ]number of responses[quot ]. Nine levels were stimulated. Acid perfusion and clearance tests were performed at the same session. Test positivity was accepted when some test evoked spontaneous patient’s symptoms. RESULTS: When 9 levels were stimulated, balloon reproduced symptoms in 77.5


. If only one level was considered, the maximal rate was 51


, responses with volumes of + < 7 ml. were obtained. In all patients with chest pain upper endoscopy was normal. In 70


of the total group and in 62.5


of patients with pirosis the acid perfusion test was [quot ]positive[quot ]. Esophagitis increased the probability of a positive test. In sixty per cent, patients with combined pirosis and chest pain responded separately with each test. In 6


balloon evoked pirosis. CONCLUSION: 1) Balloon test could be considered the most useful test in mechano-sensitivity investigation. 2) acid perfussion was useful for chemo-sensitivity investigation. As esophagitis increases chemosensitivity, it could be a conditionant factor in some patients. 3) Patients with combined symptoms responded as a mixed sensorial dysfunction with each test. 4) sub-population of patients had atypical responses to the provocative tests.

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