Values of biochemical markers: triglycerides, lipoproteins and apolipoproteins in the early pathogenesis of coronary arteries atherosclerosis

Blood lipid and lipoprotein values were analyzed in 42 male cadavers aged from 20-50 years old who died suddenly and unexpectedly without any cardiac history antecedent to death. All cases were selected from those who died and referred to the Morgue of Forensic Medicine Department, Criminal Evidence, Ministry of Interior, Kuwait, during the period between August 1999 and July 2000. A total number of 30 adult male subjects who died from non-cardiac causes were used as a control group. A statistical significant difference was found between the two studied groups as regards age, total cholesterol [T-Chol], triglycerides [TG], low density lipoprotein [LDL], high density lipoprotein [HDL], Apo A1, Apo A11 lipoproteins and Apo B lipoprotein. Also, a significant difference in the degree of narrowing of coronary arteries was found. Among the cardiac group, TG, HDL, LDL, Apo A1, Apo B parameters were found to be an effective biochemical markers when coronary arteries narrowing exceed 50%. Furthermore, using multiple logistic regression of significant risk factors that predict coronary atherosclerosis showed that high density lipoprotein [HDL] and Apo B were a significant risk predictor

Comparative study of the toxic and histopathological effects of domestic butane and town gases mice

This work aimed to study pathological changes in different parenchymatous organs of mice acutely exposed to different concentrations of butagas and town gas. It was conducted on 35 mice divided into seven groups of five mice each, one group acted as a control. The animals were decapitated and blood samples were taken to detect level of COHb. Brain, heart, lungs, liver and kidneys were studied histopathologically to detect different pathological changes. No significant morphological difference between both gases of the same concentration was detected. The changes were in the form of edema, hemorrhage and mild inflammatory infiltrate with sublethal doses; while with lethal doses, necrotic foci were detected in some organs

Histopathological and ultrastructural changes in opiate-related deaths

This study was carried out to highlight histopathological and ultrastructuralchanges in livers, kidneys and lungs of 35 opiate related fatalities. Thestudy also included a comparative study of ten accidental fatalities ofhealthy subjects served as controls. The study revealed that causes of deathin the selected series of autopsy were opiate intoxication [57%], violence[suicide, homicide or accidental, 17%] and medical complications [26%] aspneumonia and acute renal failure. The mean concentrations of morphine inblood were 20.5 +or- 3.7, 2.8 +or- 0.94 and 3.36 +or- 1.1 ug/dL in the threegroups, respectively. Light microscopic examination of the liver revealedcentrilobular sinusoidal dilatation with thickening of perisinusoidal wall andvenular wall in all cases of opiate abuse. However, in the lung, evidence ofpulmonary edema was observed in 86% of the cases with intraalveolar red bloodcells and birefringent materials and siderophages were present in 93% of thecases. Examination of renal tissue showed histologic signs of toxic acutetubular necrosis in 20% of the cases, while other cases showed evidences ofmembranoproliferative glomerulonephritis. Electron microscopic examination ofliver sections revealed that ultrastructural changes may occur as a result ofeither sinusoidal dilatation secondary to terminal hepatic vein damage or adirect cellular effect of the drug causing perisinusoidal fibrosis

qualitative technique for routine human identification by using lateral x-ray images of head

A qualitative identification technique was designed and performed on 200 adultmale cadavers. Lateral X-ray images were taken for the head in each case andthe unrequired spaces of the images were minimized. The X-ray images werethen photographed in group [6-10 cases in each picture]. The pictures werearranges in a file form [10 cases in each row of the page, making it possibleto group 100 cases in one page]. Contact tracing was then performed onfrontal sinus, forehead boundary, jaws and teeth. Zoom pictures were alsotaken for those compartment. The study revealed that the contrast of frontalsinus and its details were high in lateral X-ray film, and there were no twopersons identical in the appearance of this sinus. Examination and contracttracing of forehead boundaries and linear details of jaws, teeth and spacesbetween them showed also great variations in these details among persons. Thetechnique designed in this study is simple, reliable, and economic. It doesnot require high technical or professional procedures. It could be applied asan identification system in routine fields particularly in mass disasters aswell as in criminal identification