Cytotoxic effects of the Arum Palaestinum in Vitro

A hot water-soluble extract was obtained from the leaves of the Arum palaestinum and was subjected to cytotoxic bioassay in vitro against three tumor cell lines; Hep-2 [Larynx carcinoma] rhabdomyosarcoma and Hela [cervix carcinoma] using the MTT-assay technique. A moderate cytotoxicity of the hot extract against the three cell lines [IC50 14-20 [micro]g/ml]. The activity of the extract was compared with those of the reference standards, the cisplatin, the carboplatin and the oxaliplatin [IC50 0.3-38.7 [micro]g/ml]. The significance of these results is discussed

Male sexual dysfunctions following abdomino-perennial resection of the rectum for cancer

Sexual potency involves the psychic desire for sexual inter course together with normal erection, ejaculation and orgasm. Of these four factors, ejaculation and erection are most often affected after surgery for renal carcinoma. The age of the patient and the extent of the disease seemed to be the two main factors concerned with sexual dysfunctions after such surgery. Incidence and management of sexual dysfunctions after abdomino-perineal resection were reported in 16 patients who were less than 50 years of age. Total number of patients with sexual dysfunctions was II [69%]. Seven cases [44%] were important. Four of them were successfully treated by Finney's hinged paired silicone penile prosthesis. Four cases [25%] reported no ejaculation with normal potency and sensation of orgasm. Of these 4 cases with no ejaculation, 2 proved to have retrograde ejaculation [12.5%] which responded to alpha-adrenergic drugs. This risk of sexual dysfunction an therapeutic modalities should be discussed with each patient preoperatively