Changes of some biochemical markers and cardiac function in New Zealand rabbits with chronic heart failure / 中国应用生理学杂志

OBJECTIVE@#This article investigated the changes of some biochemical markers and cardiac function in chronic heart failure (CHF), and provided the basis for the diagnosis of CHF.@*METHODS@#New Zealand rabbit CHF model was established using adriamycin (ADR). Twenty New Zealand rabbits were randomly divided into model group (=15) and control group (=5), injected with ADR and saline solution the ear vein respectively, 2 times a week, lasting for 8 weeks. After that, myocardial enzymes, carotid artery pressure, echocardiogram (ECG) and phonocardiogram (PCG) of all New Zealand rabbits were detected and recorded.@*RESULTS@#Compared with control group, all parameters of the model group were changed significantly (<0.05).@*CONCLUSIONS@#CHF leads to myocardial damage in New Zealand rabbits, decreased systolic and diastolic function, cardiac reserve index can be used to assess cardiac function.

Research on a new method and index for evaluating cardiac function of the athletes / 中国应用生理学杂志

<p><b>OBJECTIVE</b>To explore the new indexes and new methods for the noninvasive measuring and evaluating cardiac function detection of the athletes.</p><p><b>METHODS</b>Heart sound signals were sampled randomly from 81 students in physical education department (experiment group) and 41 students in general departments (control group) after completing designed workload during step-climbing exercise, the contrast study on heart rate, D/S ratio as well as the S1/S2 ratio of students from physical education and general department has been conducted.</p><p><b>RESULTS</b>In the resting state, the physical education department students' heart rate and D/S ratio was 66 +/- 8.7 and 2.04 +/- 0.33 respectively; general department students' heart rate and D/S ratio was 71 +/- 8.0 and 1.82 +/- 0.27 respectively. In the whole exercise, the physical education department students S1/S2 ratio was 7.34 +/- 4.04; general department students S1/S2 ratio was 5.22 +/- 2.38.</p><p><b>CONCLUSION</b>Students from physical education department have higher level of cardiac reserve than that of students from general department. The method can evaluate cardiac reserve for athletes and general persons, and provide a new quantity evaluation index for selecting athletes and evaluating cardiac function of general persons.</p>