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1.
EMHJ-Eastern Mediterranean Health Journal. 2006; 12 (5): 582-589
in English | IMEMR | ID: emr-156915

ABSTRACT

Our prospective hospital- based study examined frequency, clinical presentation and serological indicators of coeliac disease that correlated with intestinal biopsy among high- risk Sudanese children. From July 2001 to July 2002, 80 children aged 15 months- 18 years presented with poor appetite, weight loss, pallor and proximal muscle wasting. We diagnosed coeliac disease in 18 [22.5%]. Antigliadin antibodies [AGA- IgG, AGA- IgA or both] were high in 44; endomysial antibody retest was high in 30. Guardians of 12 children refused consent for biopsy. The other 18 were biopsied: 5 had total villous atrophy, 8 subtotal and 5 partial. All improved with gluten- free diet. Degree of villous atrophy did not correlate with diarrhoea duration or severity, anaemia severity or serological titres


Subject(s)
Adolescent , Child , Child, Preschool , Humans , Infant, Newborn , Celiac Disease/immunology , Celiac Disease/diagnosis , Gliadin/immunology , Immunoglobulin A , Intestinal Mucosa/pathology
2.
Alexandria Dental Journal. 1996; 21 (2): 1-13
in English | IMEMR | ID: emr-40233

ABSTRACT

Oral HEs are exceedingly rare tumors. Six cases were included in the present study. All Patients were females and the tumors arise mostly from the gingiva, appeared as a large epulides; misdiagnosed as pyogenic granuloma or peripheral giant cell granuloma. No radiolucencies were observed except in three cases which recurred after surgical removal. These recurred three cases showed malignant criteria of pleomorphism, hyperchromatism and brisk mitotic figures more than the other three cases. All the patients were serologically positive to EBV, denoting previous infection. Biopsies were taken from all cases and stained for histochemical and histopathological examination. Immunohistochemical analysis was done using monoclonal antibodies for the demonstration of [1] Factor VIII related antigen,[2] Epstein -Barr virus [EBV]. Histological examination showed that three of the haemangioendotheliomas were of the epithelioid type, while the other three cases were of the spindle-cell type. All cases showed positive linear reaction to Gomori's stain surrounding the endothelidal cells and differentiating HE from haemangiopericytoma. The six cases showed the miniature luminae present intracytoplasmically by factore VIII R-AG, excluding epitheleoid haemangioma and squamous cell carcinoma. Expression of EBV in five cases out of the six immunoanalyzed cases, was detected for the first time in the literature


Subject(s)
Hemangioendothelioma/etiology , Immunohistochemistry , Herpesvirus 4, Human
3.
Rev. Fac. Med. (Caracas) ; 12(1): 48-60, ene.-jun. 1989. ilus
Article in Spanish | LILACS | ID: lil-86787

ABSTRACT

Este es un informe de seis pacientes con lesiones de la columna vertebral dorsal, anteriormente situadas y de tratamiento con descompresión a través de la ruta anterior y lateral transcavitaria; en el mismo tiempo quirúrgico se redujo y estabilizó la columna vertebral mediante instrumentación posterior con Tallos de Harrington. Esta serie incluyó dos casos de mal de Pott, tres de traumatismos raquimedulares severos y uno de condroma vertebral. Las indicaciones principales para la intervención quirúrgica fueron: compresión anterior de la médula espinal dorsal por masas, huesos o cartílagos, dolor rebelde al tratamiento convencional y cifosis. Los resultados del tratamiento quirúrgico fueron evaluados en términos de descompresión adecuada reducción quirúrgica y estabilización bajo visión directa; todo esto sin complicaciones de significación, a pesar de haber practicado toracotomía en cinco casos. En relación clínica, mejoría del déficit neurológico preoperatorio fue informada en cuatro pacientes, el dolor desapareció en los otros dos casos y el tiempo de estada, antes de empesar la rehabilitación, estuvo comprendido entre 10 y 15 días. En ninguno de los pacientes el déficit neurológico empeoró como resultado de la intervención quirúrgica, esto a pesar de la sección de al menos dos pedículos segmentarios intercostales. La revisión de la literatura y los resultados satisfactorios obtenidos en esta pequeña serie refuerzan la necesidad de renovar el entusiasmo de los neurocirujanos hacia este tipo de abordaje, en aquellos casos de lesiones anteriormente situadas y que compriman la médula espinal a nivel dorsal


Subject(s)
Adolescent , Adult , Middle Aged , Humans , Surgical Procedures, Operative , Spinal Cord Injuries/surgery
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