Personal glucose meters coupled with signal amplification technologies for quantitative detection of non-glucose targets:Recent progress and challenges in food safety hazards analysis / 药物分析学报

Ensuring food safety is paramount worldwide.Developing effective detection methods to ensure food safety can be challenging owing to trace hazards,long detection time,and resource-poor sites,in addition to the matrix effects of food.Personal glucose meter(PGM),a classic point-of-care testing device,possesses unique application advantages,demonstrating promise in food safety.Currently,many studies have used PGM-based biosensors and signal amplification technologies to achieve sensitive and specific detection of food hazards.Signal amplification technologies have the potential to greatly improve the analytical performance and integration of PGMs with biosensors,which is crucial for solving the challenges associated with the use of PGMs for food safety analysis.This review introduces the basic detection principle of a PGM-based sensing strategy,which consists of three key factors:target recog-nition,signal transduction,and signal output.Representative studies of existing PGM-based sensing strategies combined with various signal amplification technologies(nanomaterial-loaded multienzyme labeling,nucleic acid reaction,DNAzyme catalysis,responsive nanomaterial encapsulation,and others)in the field of food safety detection are reviewed.Future perspectives and potential opportunities and challenges associated with PGMs in the field of food safety are discussed.Despite the need for complex sample preparation and the lack of standardization in the field,using PGMs in combination with signal amplification technology shows promise as a rapid and cost-effective method for food safety hazard analysis.

An innovative idea and design scheme of continuous arterial blood glucose monitoring equipment / 中华危重病急救医学

Hyperglycemia is a common complication of critical patients. Currently, clinical assessment of the changes in the blood glucose of critical patients is mainly based on the intermittent monitoring of peripheral blood glucose at a certain time point. This method cannot get the true blood glucose fluctuation, and it is more difficult to find asymptomatic hyperglycemia and hypoglycemia, so the guiding value of blood glucose control is limited. Arterial blood is the most accurate sample of blood glucose monitoring, so it is urgent to ensure the accuracy of arterial blood sample. A continuous arterial blood glucose monitoring equipment was independently developed by general surgical intensive care unit (ICU) of the First Affiliated Hospital of Nanjing Medical University, and National Utility Model Patent of China was obtained. It could greatly improve the efficiency of medical staff, and provide accurate and dynamic statistic data that would be an important basis for doctors' clinical decision-making. The continuous arterial blood glucose monitoring equipment was mainly composed of arterial pressure measuring monitor, program-controlled dynamic blood glucose meter, wire, electric switch, integrated collecting syringe, electric clip, rotary electric bracket, and blood glucose test strips, etc., which could be continuously and dynamically monitor patient blood glucose levels and perform various additional value-added functions such as automatic recording and alarming.

Evaluation on influence of interference factors HCT,vitamin C and galactose on three different portable blood glucose meters / 国际检验医学杂志

Objective To evaluate the influence of hematocrit(HCT),vitamin C(Vc)and galactose on three portable blood glucose meters to provide some reference for clinical selection of appropriate blood glucose me-ter.Methods 20 heparin anticoagulant venous blood samples in the clinical laboratory department of Nanfang Hospital were selected for verifying the accuracy of blood glucose meter.2 healthy volunteers were selected for collecting 5 w hole blood samples in interferent test.Referring to the detection results of Roche automatic bio-chemical analyzer,the Nova StatStrip Xpress glucometer,Bayer Contour Plus glucometer and Roche Accu-chek Performa blood glucose meter were performed the accuracy verification.The influence of HCT,Vc and galac-tose on the detection results of above three portable blood glucose meters were evaluated.Results The detec-tion accuracy of Nova StatStrip Xpress and the Roche Accu-Chek glucometers all conformed to the require-ments of ISO15197:2013 standards.The detection accuracy of Bayer Contour Plus glucometer only conformed to the requirements of ISO15197:2003 standards.Under the interference of different levels of HCT,Vc and galactose,the detection results of Nova StatStrip Xpress glucometer conformed to the requirements of ISO15197:2013 standards;w hen detecting low concentration of blood glucose,the Bayer Contour Plus glucom-eter was interfered by 10 mg/dL Vc,and other detection results conformed to the requirements of ISO15197:2003 standards;the anti-interference performance of Roche Accu-chek Performa glucometer conformed to the

Accuracy of blood glucose measurements using capillary and arterial line of extracorporeal circuit of hemodialysis among diabetic patients undergoing outpatient hemodialysis at The Medical City

Introduction@#Accurate and reliable glucose level measurements are essential for ensuring safe and effective glycemic control among diabetic patients undergoing hemodialysis (HD). Capillary blood glucose (CBG) monitoring is the standard of care of glycemic control assessment in patients with diabetes on maintenance HD. In the Philippines, glucose monitoring during HD involves either standard finger stick (CBG) or blood sample from the arterial line (AL) of extracorporeal circuit of HD machine. However, anecdotal observations noted over the years have shown discrepancies in the glucose values from the two sites. This study aimed to determine the accuracy of blood glucose measurements of capillary and AL of extracorporeal circuit of HD machine using point-of-care (POC) glucose meter in comparison to central laboratory venous plasma among diabetic patients undergoing outpatient HD in a private tertiary hospital in the Philippines. Determining the most accurate and reliable method of glucose level measurement is vital in helping patients attain glycemic control. To date, there is limited published data regarding the accuracy of blood glucose values obtained through CBG and AL of extracorporeal circuit of HD machine while patients are undergoing dialysis.@*Methods@#This is a prospective, cross-sectional, analytical study involving thirty patients. Forty blood samples from 30 patients obtained through CBG, AL and the peripheral venous plasma of the opposite arm were simultaneously analyzed. Specifically, StatStrip was utilized as the POC glucose meter. Accuracy of AL of extracorporeal circuit and CBG were determined and assessed in accordance with International Organization for Standardization (ISO) 15197:2013 minimum accuracy criteria for glucose meters. Regression analysis was used to determine whether AL and CBG significantly predict peripheral venous blood glucose levels.@*Results@#Analysis showed that there is a statistically significant difference in the glucose values obtained from AL and CBG (p-values 0.005 and <0.0001) when compared to venous plasma glucose. However, this may not pose clinical significance in routine practice. It is noteworthy that both AL (concordance rate (CR)=100%) and CBG (CR=96.5%) satisfied the revised ISO 15197:2013 accuracy criteria for glucose value greater than or equal to 100mg/dL.@*Conclusion@#Both CBG and AL blood glucose measurement significantly predict venous plasma blood glucose level. POC blood glucose value from both AL of extracorporeal circuit during HD and CBG satisfied the accuracy criteria set by ISO 15197: 2013 for glucose value greater than or equal to 100mg/dL. Thus, confirming the glucose level by CBG monitoring is not necessary in patients with arterial glucose value of greater than or equal to 100 mg/dL during HD.

Comparative analysis of GM260 portable blood glucose meter and AU5821 automatic biochemical analyzer / 医疗卫生装备

Objective To compare GM260 portable blood glucose meter and AU5821 automatic biochemical analyzer in order to prove the accuracy of GM260 and its applicability for clinical use.Methods Totally 20 pieces of EDTA-K2 anticoagulative specimens and 23 GM260 meters were numbered,and each specimen underwent examinations by both GM260 and AU5821,then the bias between the two kinds of devices was calculated.Results The maximal bias between GM260 and AU5821 was 0.47 mmol/L and all the meters had the bias between-0.83 and 0.83 mmol/L in case of 5 specimens with the glucose concentration less than 4.2 mmol/L;the maximal bias between GM260 and AU5821 was 18.07％ and all the meters had the bias between-20％ and 20％ in case of 15 specimens with the glucose concentration not less than 4.2 mmol/L;the examination results by GM260 all accorded with industrial standard.The results by GM260 were lower than those by AU5821,and the maximal negative deviation was-13.43％.Conclusion Portable blood glucose meter can only be used for screening,and automatic biochemical analyzer is the preferred device for diabetes diagnosis.

Application of informatized blood glucose management system to diabetes patient outside hospital / 医疗卫生装备

Objectivde To explore the efficacy of i-GMS applied to the diabetes patient outside the hospital.Methods Totally 80 type 2 diabetes mellitus patients were divided into an experiment group (Group A) and a control group (Group B).Group A executed blood glucose monitoring by Glucose Management App and intelligent blood glucose meter (personal version),and Group B completed monitoring by some portable blood glucose meter.Telephone follow-up was performed once a week,and the two groups were compared on glycated albumin (GA) value 3 weeks after discharging,values of HbA1c,FPG and PG2h 3 months after,the times of blood glucose monitoring and hypoglycaemia as well as the patient satisfaction over the glucose management.Results Group A had the values of GA,HbA1c,FPG and PG2h significantly lower than those of Group B (P＜ 0.05).The times of glucose monitoring and patient satisfaction in Group A were statistically higher than those of Group B,while the incidence rate of hypoglycaemia of the former was lower than that of the latter (P＜0.05).Conclusion I-GMS proves efficient when used for glucose self monitoring and management of the type 2 diabetes mellitus patient.

Implementación y evaluación de un programa de gestión de calidad para el monitoreo de glucómetros en un hospital universitario / Implementation and evaluation of a management program quality for monitoring glucometers in a hospital academic

Introducción: El uso de dispositivos portátiles para controlar la glucemia se ha extendido en los últimos años a las entidades hospitalarias, porque proporcionan un resultado rápido al realizarse al lado de la cama del paciente (point-of-care testing). Objetivo: Describir el proceso y los resultados de la implementación de un programa de gestión de calidad para el control de glucómetros hospitalarios. Materiales y Métodos: Se presenta la implementación de un programa de gestión de calidad para evaluar 50 glucómetros pertenecientes a siete áreas críticas del Hospital Italiano de Buenos Aires (Unidad Coronaria, Terapia Intensiva de Adultos y Pediátrica, Terapia Intermedia, Central de Emergencias de Adultos y Pediátrica, Unidad de Cuidados Intensivos Neonatológicos), desde el 1 de enero de 2014 hasta la actualidad, basado en tres estrategias: control diario, análisis mensual (precisión y exactitud) y control de muestras paralelas. Resultados: Luego de instaurar este programa y analizar los datos de los primeros 17 meses, se requirió un recambio total de 292 glucómetros: 150 debido al control de calidad diario, 119 por el análisis mensual y 23 por el control de muestras paralelas. Esto implicó retirar 17/50 glucómetros por mes. Conclusiones: Si bien estos dispositivos son útiles por su rápida respuesta, el 34,6% debió ser reemplazado por no haber superado alguno de los requisitos planteados en las estrategias de evaluación. La peor performance fue en los niveles de hipoglucemia, situación de interés para la rápida toma de decisiones. Es importante destacar la necesidad de aplicación de un plan de calidad para glucómetros sobre la base de un diseño propio y a medida de la institución para garantizar la seguridad del paciente.(AU)

Introduction: The use of portable devices for glycemic control has been extended in recent years to hospital entities, because they provide a rapid result when they are performed at or near the patient's bedside (point of care testing). Objective: To describe the process and results of the implementation of a quality management program to control of hospital glucometers. Materials and Methods: We present the implementation of a quality management program to evaluate 50 glucometers belonging to seven critical areas of Hospital Italiano de Buenos Aires (Coronary Unit, Adult and Pediatric Intensive Care Unit, Intermediate Therapy, Adult and Pediatric Emergency Center, Unit of Neonatal Intensive Care), from January 1, 2014 to the present, based on three strategies: Daily Control, Monthly Analysis and Control of Parallel Samples. Results: After implementing this program and analyzing the first 17 months, the substitution of 292 glucometers was required: 150 due to daily quality control, 119 per monthly analysis and 23 due to control parallel samples. This involved withdrawing 17/50 glucometers monthly. Conclusions: Although these devices are useful because of their rapid response, 34.6% had to be replaced because they exceeded the requirements presented in the evaluation strategies. The worst performance was in levels of hypoglycemia, a situation of interest for rapid decision-making. It is important to emphasize the need to apply a quality plan for glucometers based on an own design and suitable for the institution to guarantee the safety of the patient.(AU)

Factores de riesgo asociados a la hipoglicemia en neonatos de riesgo

Introducción: La hipoglicemia es común en el recién nacido (RN) pero si es persistente o muy profunda puede generar secuelas neurológicas. Los objetivos de esta investigación fueron describir los valores de glicemia capilar de los recién nacidos de riesgo y determinar los factores de riesgo de hipoglicemia de los neonatos de riesgo del Hospital Nacional (Itauguá, Paraguay). Materiales y Métodos: Se midió la glicemia capilar con glucómetro digital en los RN de riesgo Hospital Nacional (Itauguá, Paraguay) entre mayo 2015 y febrero 2016. Para determinar los factores de riesgo se aplicó luego un diseño de casos (RN con hipoglicemia) y controles (RN sin hipoglicemia). Las variables independientes fueron las patologías asociadas del RN, prematurez, restricción del crecimiento intrauterino, parto por cesárea, sexo del RN, hipertensión arterial y diabetes gestacional. Resultados: Se incluyeron 76 RN, 56,6% del sexo masculino, con edad gestacional media 36±3 semanas, con mediana de peso 2.569 g, nacidos por cesárea en 68,4%. Se encontraron 25 RN con hipoglicemia <47 mg/dL (casos) y 51 sin hipoglicemia (controles). Los factores de riesgo estadísticamente significativos asociados a la hipoglicemia neonatal fueron la prematurez y la presencia de patologías asociadas: dificultad respiratoria, sepsis y asfixia perinatal. Se halló considerable correlación entre glicemia capilar y glicemia plasmática (r +0,6). Conclusiones: Los factores de riesgo estadísticamente significativos asociados a la hipoglicemia neonatal fueron la presencia de patologías asociadas (dificultad respiratoria, sepsis y asfixia perinatal) y la prematurez. La correlación entre la glicemia capilar y la plasmática fue considerable (r+0,6).

Introduction: Hypoglycemia is common in the newborn (RN) but if it is persistent or too deep can cause neurological sequelae. The objectives of this study were to describe the values determined by capillary glycemia digital glucometer in the RN risk and analyze the risk factors associated with hypoglycemia. Materials and Methods: Capillary glucose was measured with digital glucometer in the risk RN National Hospital (Itauguá, Paraguay) between May 2015 and February 2016. To determine the risk factors design cases (RN with hypoglycemia) was then applied and controls (RN without hypoglycemia). The independent variables were associated pathologies RN, prematurity, intrauterine growth restriction, cesarean birth, sex RN, high blood pressure and gestational diabetes. Results: RN 76 were included, 56.6% male, mean age 36 ± 3 gestational weeks with median weight 2,569 g, born by Caesarean section at 68.4%. RN 25 were found with hypoglycemia <47 mg / dL (cases) and 51 without hypoglycemia (controls). Statistically significant risk factors associated with neonatal hypoglycemia were prematurity and the presence of associated diseases: respiratory distress, sepsis and perinatal asphyxia. It was found significant correlation between capillary glycemia and plasma glucose (r +0.6). Conclusions: Significant risk factors statistically associated with neonatal hypoglycemia were the presence of associated diseases (respiratory distress, sepsis and perinatal asphyxia) and prematurity. The correlation between capillary glucose and plasma was significant (r + 0.6).

The influence of hematocrit on the consistency between blood glucose meters and automatic biochemical analyzer for testing blood glucose of peripheral blood and venous blood / 中国医学装备

Objective:To study the influence of hematocrit on the consistency between blood glucose meters and automatic biochemical analyzer for testing blood glucose of peripheral blood and venous blood.Methods: 200 cases of diabetic and non-diabetic patients were selected in our hospital from January 2013 to September 2015, in which 124 cases were diabetics and 76 cases were non-diabetics. All the selected patients were treated with venous blood and peripheral blood glucose testing by the SIEMENS ADVIA1800 full automatic biochemical analyzer and three brand of blood glucose meters (Reiter GM300, Arkray GT-1920, Johnson & Johnson One Touch), comparing their consistency.Results: The hematocrit range was 35.1~51.6%, accounted for 91.0%(182), 25.0~35.0% of patients accounted for 9.0%(18), and average hematocrit was (42.3±4.2). When hematocrit was 35.1~51.6%, the correlation of automatic biochemical analyzer and Reiter GM300 blood glucose meter was high and stable, followed by Arkray GT-1920 and Johnson &Johnson One Touch. When hematocrit was 25.0~35.0%, the correlation of automatic biochemical analyzer and three blood glucose meters were high than hematocrit was 35.1~51.6%. There was no significant difference between SIEMENS ADVIA1800 automatic biochemical analyzer and Reiter GM300 about monitoring the blood glucose results, but there were significant differences between Johnson and Johnson One Touch and Arkray GT-1920.Conclusion: The automatic biochemical analyzer and three blood glucose meters have good correlation. When hematocrit is greater than 35%, the correlation is lower; when hematocrit is less than 35%, the correlation increases.

The impact of temperatures on the results tested with different blood glucose testing methods for critical patients in ICU / 中国实用护理杂志

Objective To compare the impact on the results tested with arterial blood gas analysis and peripheral blood with glucose meter for critical patients in ICU in different temperature states. Methods The samples of venous biochemical test, blood arterial blood gas analysis and peripheral blood of 196 cases of critical patients in ICU were collected synchronously, and measure the D-value, correlation and bias adjustment factor of glucose blood tested with a synchronous fasting blood glucose test and venous/biochemical analyzer in different temperature states and different blood glucose groups, and the results of blood glucose test were analyzed. Results In normal temperature state, hypoglycemia simultaneous rapid intravenous glucose monitoring blood glucose level results compared with the lowest positive rate 3.31%(5/151), while the pairwise comparison showed there was both statistical signifcance between hypoglycemia group and target group (χ2=38.469), hyperglycemia group and target group (χ2=15.504) when choosing a synchronous fasting blood glucose test and intravenous blood glucose test (P<0.01). In high temperatures state, hypoglycemia simultaneous rapid intravenous glucose monitoring blood glucose level results compared with the lowest positive rate 0. There was both statistical significance between hypoglycemia group and target group (χ2=18.187), hypoglycemia group and hyperglycemia group (χ2=12.857) when choose a synchronous fasting blood glucose test and intravenous blood glucose test (P<0.01). Conclusions In high temperatures state, a synchronous fasting blood glucose test can not reflect the true value of blood glucose for critical patients.

Self-Monitoring Blood Glucose Meter: Is Your Glucose Meter Accurate? / 임상당뇨병

Blood glucose monitoring provides immediate feedback on the effect of daily activities such as taking medication, exercise or eating on blood glucose levels. A home blood glucose meter's results are considered accurate if they falls within +/-20% of lab results. Such meters are calibrated to use whole blood to measure glucose, whereas lab equipment uses only the plasma portion. To maintain accuracy, results from a meter should be compared to those of a laboratory at least once a year. Diabetes educators should have thorough knowledge of each meter and its accuracy so that he or she can properly educate diabetic patients.

A comparative analysis on results of blood glucose detected by POCT portable glucose meters and automatic biochemical analyzer / 国际检验医学杂志

Objective To compare the results of blood glucose detected by the POCT glucose meters and the automatic biochem‐ical analyzer ,and to periodically evaluate the reliability of the portable glucose meters .Methods 22 patients with fasting blood‐glu‐cose of 0 .88 - 30 .82 mmol/L were selected and the NaF anticoagulation whole blood was collected .Each sample were detected for 3 times .The mean value was taken for conducting the bias and correlation evaluation .Results The bias of 20 glucose meters was within ± 0 .2 and PT > 80% ,and the bias of 5 glucose meters ± 0 .2 in 2 - 6 concentration values .Conclusion The testing results of 20 glucose meters are identical with those detected by the biochemical analyzer and meet the accuracy standards stipulated by the Ministry of Public Health ,and 5 glucose meters have relatively big differences .

Development of the medical equipment maintain information system / 中国医学装备

Objective:To design and construct a blood glucose meter quality control management information system. Methods:according to the existing portable blood glucose meter in use process problem, in the analysis of the current hospital existing blood glucose meter management mode and method of quality control, puts forward the design scheme of quality control management information system. Results:The function of the system includes blood glucose meter account information management, quality control records management, and biochemical comparison results management, management rules and related management system and instruments in the course of using the consumable management, to realize the dynamic management of the quality control of blood glucose meter. Conclusion:through the application of blood glucose meter quality control management system, achieved to ensure the clinical safety and effectiveness of the use of.

Impact of uric acid on peripheral blood glucose tested by portable blood glucose meter / 重庆医学

Objective To investigate the impact of uric acid on peripheral blood glucose measured by the portable blood glu‐cose meter .Methods A total of 60 inpatients with 2 diabetic mellitus(T2DM ) complicating hyperuricemia were chosen as the re‐search group and contemporaneous 60 cases of T2DM without complicating hyperuricemia as the control group .Blood glucose in both groups was measured by the portable blood glucose meter ,meanwhile plasma glucose and serum uric acid were assessed by the biochemical analyzer in order to explore the impact of uric acid on peripheral blood glucose .Results (1)The difference between pe‐ripheral blood glucose and venous blood glucose was correlated with serum uric acid .(2)There was statistically significant differ‐ence in the blood glucose between the two groups .(3 ) The bias of blood glucose value were within the acceptable range . Conclusion Serum uric acid has certain influence on the peripheral blood glucose ,but which is within the acceptable range .The de‐tected blood glucose value of the portable blood glucose meter can be trusted .

Performance evaluation of 20 blood glucose meters for home use testing / 国际检验医学杂志

Objective To evaluate the precision and accuracy of blood glucose meter(BGM ) for community home use testing . Methods According to the In Vitro Diagnostic Test Systems‐Requirements for Blood Glucose Monitoring Systems for Self‐Testing in Managing Diabetes Mellitus in DIN EN ISO15197 :2013 .Capillary blood and venous blood were tested by BGM and the laborato‐ry biochemical analyzer respectively .The measurement results of each BGM were compared with the results of the biochemical ana‐lyzer for conducting the bias analysis .Results In evaluated 20 BGM ,none of them met the requirements of ISO15197 :2013(when blood glucose concentrations < 5 .5 mmol/L ,the bias in 95% of detection results is within the range of ± 0 .83 mmol/L ;when blood glucose concentrations ≥ 5 .5 mmol/L ,the bias in 95% of detection results is within the range of ± 15% .Only 11 imported BGM (55% ) met the state standard .Conclusion The bias of 20 BGM ranged - 28 .7% - 3 .8% ,with the average bias of - 12 .2% . These detection results will bring the large risk of therapy in the diabetic patients .The regular and standardized evaluation of BGM performance may ensure the quality of blood glucose self - monitoring .

Application value of fast blood glucose meter in emergency inspection of blood glucose / 国际检验医学杂志

Objective To explore the clinical application value of fast blood glucose meter in the emergency test of blood glu‐cose .Methods 186 critical patients in or hospital from August 2013 to August 2014 were selected for conducting the clinical re‐search .The average blood sugar was detected in all the research subjects by using the fast blood glucose meter and the fully auto‐matic biochemical analyzer .Results The consistency rate of detection results by the two kinds of detection method reached 22 .04% ,the difference of data was relatively small .In addition ,the detection time for the fast blood glucose meter was significantly shorter than that of the fully automatic biochemical analyzer ,the difference showed the statistical significance (P< 0 .05) .Conclu‐sion The detection results of the fast blood glucose meter have no too large difference with those of fully automatic biochemical an‐alyzer and have the same guidance significance to the diagnosis and treatment .The fast blood glucose meter has the advantages of quickness and convenience ,short time‐consuming and can be used in emergency .

Evaluation of 2 methods for comparing the glucose measurement between glucose meter and automatic analyzer / 国际检验医学杂志

Objective To compare the evaluation effect ,clinical feasibility and influencing factors of two methods on comparative analyzing the blood glucose measurement of glucose meter and automatic analyzer .Methods 61 diabetic or non-diabetic patients were recruited in this study .All subjects were drawn 2 mL fasting venous blood using EDTA-K2 tubes following an 8~12 h over-night fast .One drop of venous whole blood was used to measure the blood glucose concentration (VBG)with the meter and the rest of blood was centrifuged for detecting the plasma glucose (VPG)by automatic analyzer (HITACHI-7600) .The capillary blood was taken by finger stick to test blood glucose(CBG)using the same meter within 5 min after the venous blood collection .Taking the VPG as the reference ,to calculate the respective bias of VBG and CBG .Correlation of VPG with VBG or CBG was analyzed .The clinical acceptance of glucose meter readings was evaluated by Parkes error grid analysis .Results Both VBG and CBG measured by Accu-Chek Performa glucose meter were highly correlated with VPG ,with correlation coefficient 0 .991 and 0 .989 respectively .All the measurements satisfactorily met the GB/T 19634-2005 criteria and all the results were clinically accepted .Conclusion To com-pare the results of blood glucose measured by glucose meter and automatic analyzer ,venous blood sample is recommended because of the same blood resource ,convenience of operation and possibility of making blood samples with extremely low or high glucose concentration .

Practice of standardized management of the portable blood glucose meter / 中国医学装备

Objective: To apply the norms of the portable blood glucose meter in clinic and improve the quality and level of blood glucose detection. Methods:The management organization of the portable blood glucose meter was established. The organization understudied the working principles and the advantages and disadvantages of blood glucose meter. The model of the portable blood glucose meter was unified in a medical unit. The performance of the portable blood glucose meter and the biochemical analyzer was compared. The organization established standard operating procedures, strengthen personnel training. The clinical staff takes quality control regular. Results:The qualified rate of the use, the maintenance and the results detection was increased. Conclusion:The standardized management system guarantees the detection result of the portable blood glucose meter.

Avaliação de dois sensores portáteis para mensuração da glicemia em cães / Evaluation of two portable meters for blood glucose measurements in dogs

Avaliou-se a precisão analítica e clínica de dois sensores portáteis para mensuração da glicemia em cães. Os valores da mensuração da glicemia obtidos com os sensores foram comparados com aqueles obtidos pelo método padrão da glicose oxidase, por meio da análise de correlação e da análise da grade de erros. Os resultados gerados pelos sensores não foram diferentes do método padrão. Conclui-se que ambos os sensores são adequados para mensuração da glicemia em cães

The clinical and analytical accuracy of two portable meters for glucose measurement in dogs was evaluated. Blood glucose values obtained by the use of portable meters were compared to those obtained using the glucose oxidase reference method, by means of correlation and error analysis. Results obtained with the blood glucose meters were not different from those obtained with the reference method. Both apparatus evaluated are adequate for use in dogs