ABSTRACT
Objective: To investigate the chemical constituents of alcohol extract of Mori Fructus. Methods: The chemical constituents were isolated and identified by chromatography on silica gel, Sephadex LH-20, ODS, and RP-HPLC. Their structures were elucidated on the basis of physicochemical properties and spectral analyses. Results: Twelve compounds were isolated from the alcohol extract of Mori Fructus, and identified as mullignanoside (1), (7R,8S)-4,7,9,9’-tetrahydroxy-3,3’-dimethoxy-8-O-4’-neolignan- 9’-O-β-D-glucopyranoside (2), 2-phenylethyl-β-D-glucopyranoside (3), 1’-O-phenethyl-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside (4), benzyl-O-β-D-glucopyranoside (5), ergosterol peroxide (6), (24R)-6β-hydroxy-24-ethyl-cholest-4-en-3-one (7), (22E)-5α,8α- epidioxy-24-methyl-cholesta-6,9(11),22-trien-3β-ol (8), trans-(S)-(+)-abscisic acid (9), cis-(S)-(+)-abscisic acid (10), (S)-(+)-1- methyl-abscisic-6-acid (11) and phaseic acid (12). Conclusion: Compound 1 is a new compound named mullignanoside, and compounds 2, 7-12 are isolated from this plant for the first time.
ABSTRACT
Objective: To study the chemical constituents of Artemisia argyi. Methods: The chemical constituents were isolated by silica gel column chromatography and HPLC, and its structure were identified by their spectral data and physicochemical properties analysis. Results: Thirty-four compounds were isolated from A. argyi with the structures identified as 5-hydroxy-6,7,3’,4’- tetramethoxyflavone (1), eupatorin (2), p-hydroxy-acetophenone (3), raspberry ketone (4), zingiberone (5), 7-hydroxycoumarin (6), p-hydroxybenzoic acid (7), desacetoxymatricarin (8), 3α-hydroxy-1(10),4,11(13)-triene-12,6α-olide (9), jaceosidin (10), 7-hydrxyterpineol (11), cis-2,8-dihydroxy-p-mentha-1(7)-en (12), trans-2,8-dihydroxy-p-mentha-1(7)-en (13), artemisetin (14), scopoletin (15), arteminolide C (16), desacetylmatricarin (17), artecalin (18), 11,13-dehydrodesacetylmatricarin (19), 1,9-azelaic acid (20), 3-methoxy-tanapartholide (21), phaseic acid (22), seco-guaiaretic acid (23), 5,3’,4’-trihydroxy-6,7-dimethoxy-flavone (24), 1,7-pimelic acid (25), 10-epi-ajafinin (26), 3-epi-iso-seco-tanapartholide (27), austroyunnane C (28), artanomaloide (29), ligustolide A (30), seco-tanapartholide B (31), 3-dehydroxy-iso-seco-tanapartholide (32), 3α-hydroxyreynosin (33), dihydrophaseic acid (34). Conclusion: Compounds 4, 22, 25, 30, 33, 34 are separated from the Artemisia for the first time. Compounds 5, 7, 8, 11-13, 21, 23, 24, 26-28 are isolated from A. argyi for the first time.
ABSTRACT
Objective: To investigate the chemical constituents from Ficus pumila and to provide the material basis for quality control. Methods: The chemical constituents were separated and purified by silica gel, Sephadex LH-20, ODS, and preparative HPLC column chromatographies. Their structures were determined by physicochemical properties and spectral data analyses. Results: From 95% ethanol extract of F. pumila, 21 compounds were isolated and identified as rutin (1), kaempferol 3-O-α-L-rhamnopyranosyl (1→6)-β-D-glucopyranoside (2), isoquercitrin (3), quercitrin (4), dihydrokaempferol 5-O-β-D-glucopyranoside (5), dihydro-kaempferol 7-O-β-D-glucopyranoside (6), maesopsin 6-O-β-D-glucopyranoside (7), secoisolariciresinol 9-O-β-D-glucopyranoside (8), chlorogenic acid (9), protocatechuic acid (10), caffeic acid (11), 5-O-caffeoyl quinic acid methyl ester (12), p-hytroxybenzoic acid (13), vanillic acid (14), 5-O-caffeoyl quinic acid butyl ester (15), β-amyrin acetate (16), daucosterol (17), phaseic acid (18), vomifoliol (19), (1'S, 6'R)-8'-hydroxyabscisic acid β-D-glucoside (20), and 1-methyl-1, 2, 3, 4-tetrahydro-β-carboline-3-carboxylic acid (21). Conclusion: Compounds 5-15, 18, 20, and 21 are isolated from this plant for the first time, and compound 5-8, 12, 15, 20, and 21 are found in plants of Ficus Linn. for the first time.