Correlación entre las pruebas de antígeno prostático específico rápida y sérica / Correlation between rapid and serum prostate-specific antigen tests

Introducción: Al día de hoy no se ha alcanzado un consenso sobre el mejor enfoque para realizar el tamizaje y la detección precoz del Cáncer de Próstata (CaP), en la población. No obstante, hay programas que recomiendan la utilización de la prueba de antígeno prostático específico rápida para la detección de CaP sin un análisis de correlación frente a la prueba sérica. Objetivo: Identificar la correlación entre las pruebas de antígeno prostático específico rápida y sérica, en la población mexicana. Métodos: Se realizó un estudio descriptivo, transversal y retrospectivo, bajo un muestreo no probabilístico por conveniencia. En el período comprendido entre el 25 de mayo al 13 de julio de 2017. Se calcularon los coeficientes de correlación punto biserial (r pb ) y phi (r phi ). Resultados: Se incluyeron 1 635 registros, principalmente de la Ciudad de México y del Estado de México (n= 1 398; 85,5 por ciento, IC95 por ciento 81-89,9). La edad promedio fue de 51 años (DE= 7,68). El valor promedio de antígeno prostático sérico fue de 1,49 ng/mL (DE= 1,91). La proporción de hombres con una prueba rápida positiva (n=60; 3,7 por ciento; IC95 por ciento 2,9-4,6) fue menor (p= 0,0415) en comparación con la proporción de pacientes con una prueba sérica ≥ 4 ng/mL (n=85; 5,2 por ciento; IC95 por ciento 4,1-6,3). El número de casos dobles negativos fue de 1 530 (93,6 por ciento; IC95 por ciento 92,3-94,6) y de dobles positivos fue de 40 (2,4 por ciento; IC95 por ciento1,7-3,2). Los coeficientes de correlación punto biserial y phi mostraron una correlación baja entre la prueba rápida y la prueba sérica de antígeno prostático (rpb= 0,469; p < 0,001; r2= 0,2199 y r ph i= 0,540; p < 0,001; r2= 0,2916). Conclusiones: La prueba de antígeno prostático específico rápida es una herramienta conveniente para los programas de detección de alteración prostática en unidades médicas del primer nivel de atención, donde la prueba sérica no se puede realizar, al ser una prueba con una baja sensibilidad y con un bajo coeficiente de correlación respecto de la prueba de antígeno prostático específico sérica, esto es un punto importante que debe considerarse al diseñar programas de detección oportuna de cáncer de próstata(AU)

Introduction: To date, no consensus has been reached on the best approach for screening and early detection of Prostate Cancer (PCa) in the population. However, there are programs recommending the use of the rapid prostate-specific antigen test for the detection of PCa without a correlation analysis versus the serum test. Objective: To identify the correlation between rapid and serum prostate specific antigen tests in the Mexican population. Methods: A descriptive, cross-sectional and retrospective study was carried out, under a non-probabilistic convenience sampling from May 25 to July 13, 2017. The correlation coefficients of point biserial (rpb) and phi (rphi) were calculated. Results: One thousand six hundred thirty five (1,635) records were included, mainly from Mexico City and the State of Mexico (n= 1,398; 85.5 percent, 95 percent CI 81-89.9). The average age was 51 years (SD= 7.68). The mean value of serum prostate antigen was 1.49 ng/ml (SD= 1.91). The proportion of men with positive rapid test (n=60; 3.7 percent; 95 percent CI 2.9-4.6) was lower (p= 0.0415) compared to the proportion of patients with a serum test ≥ 4 ng/ml (n= 85; 5.2 percent; 95 percent CI 4.1-6.3). The number of double negative cases was 1,530 (93.6 percent; CI95 percent 92.3-94.6) and of double positives was 40 (2.4 percent; CI95 percent 1.7-3.2). The point biserial and phi correlation coefficients showed low correlation between the rapid test and the serum prostate antigen test (rpb= 0.469; p < 0.001; r2= 0.2199 and rphi= 0.540; p < 0.001; r2= 0. 2916). Conclusions: The rapid prostate-specific antigen test is a convenient tool for prostatic alteration detection programs in primary care medical units, where the serum test cannot be performed, however, as it is a test with low sensitivity and with low correlation coefficient with respect to serum prostate-specific antigen testing, this is an important point to consider when designing prostate cancer early detection programs(AU)

Aplicación del método de Graf para el diagnóstico y tratamiento oportuno de displasia de cadera / Application of the Graf method for diagnosis and early detection of hip dysplasia

Resumen: Introducción: La displasia del desarrollo de cadera (DDC) es el trastorno más común que afecta la cadera pediátrica; hacer tamizaje a todos los neonatos en forma clínica y utilizar ultrasonografía en forma selectiva para aquellos bebés que se encuentran con alto riesgo es una recomendación muy difundida. Nuestro objetivo es evaluar el impacto que ha tenido el diagnóstico por ultrasonografía (USG) y tratamiento temprano de la DDC en la población infantil de nuestra unidad. Material y métodos: Estudio retrospectivo, descriptivo y transversal. Se revisaron expedientes de aquellos niños de uno a seis meses de edad, con diagnóstico de DDC, sin distinción de sexo, sometidos a rastreo ultrasonográfico en el período de Enero de 2018 a Diciembre de 2019. Se realizó un seguimiento de seis meses en todos los pacientes, a partir del momento del diagnóstico y del inicio de tratamiento con arnés, visitas semanales para recolocación, así como realización de rastreos ultrasonográficos cada cuatro semanas para monitorización del tratamiento. Resultados: Se reportaron 19 casos del lado izquierdo (47.5%), 10 casos del lado derecho (25%) y 11 casos bilaterales (27.5%). Los principales factores de riesgo asociados fueron: producto de la primera gesta, antecedentes familiares de DDC, presentación pélvica, sexo femenino. Los resultados fueron favorables con un uso continuo de arnés de 23 horas, se observó una evolución satisfactoria en 99.2% de los pacientes. Conclusión: Con los resultados obtenidos podemos analizar la tasa de éxito considerable de la clínica de cadera de nuestro hospital con la realización del ultrasonido, encontramos una menor incidencia de pacientes con dolor, limitación de la función, así como patrones de marcha satisfactorios.

Abstract: Introduction: Developmental hip dysplasia (DHD) is the most common disorder affecting pediatric hip; screening all neonates clinically, and using ultrasonography selectively for those babies who are at high risk is a widespread recommendation. our goal is to evaluate the impact that USG diagnosis and early treatment of DHD has had on the child population of our unit. Material and methods: Retrospective, descriptive and cross-sectional study. Records of those children from one to six months of age, with a diagnosis of DHD, without distinction of sex, subjected to ultrasonographic tracking in the period from January 2018 to December 2019 were reviewed. A follow-up of six months was carried out in all patients, from the moment of diagnosis and the start of treatment with harness, weekly visits for relocation, as well as ultrasonographic revision every four weeks to monitor the treatment. Results: 19 cases were reported from the left side (47.5%), 10 cases from the right side (25%) and 11 bilateral cases (27.5%). The main associated risk factors were: product of the first pregnancy, family history of DHD, pelvic presentation, female sex. The results were favorable with a continuous use of harness of 23 hours observing a satisfactory evolution in 99.2% of the patients. Conclusion: With the results obtained we can analyze the considerable success rate of the hip clinic of our hospital with the realization of the ultrasound, we find a lower incidence of patients with pain, limitation of function, as well as satisfactory gait patterns.

Validación de los instrumentos para medir factores que influyen en el diagnóstico leucemia linfoblástica en niños / Validation of instruments to measure factors that influence the diagnosis of lymphoblastic leukemia in children

La leucemia linfoide aguda (LLA) es el cáncer más frecuente en niños. A nivel mundial se estima que cerca del 30% corresponde a la totalidad de las neoplasias malignas que se presentan en niños y de estas, más del 75% son LLA. Por esto, nos vimos en la necesidad de elaborar un instrumento para medir factores que influyen en el diagnóstico. Porque un diagnóstico oportuno contribuye a mejorar la tasa de vida de estos pacientes. Objetivo: Validar instrumentos para medir los factores que influyen diagnóstico leucemia linfoblástica en niños. Metodología: Esta es una investigación mixta, corte transversal de tipo exploratorio. Diseño descriptivo no experimental. Para validar el instrumento cuantitativo se utilizó una muestra piloto con 15 padres de familia o representes de niños diagnosticados con leucemia linfoblástica aguda, seleccionado y elegido de forma aleatoria probabilística. Para el instrumento cualitativo se utilizó a una sola madre de un niño diagnosticado con leucemia, validado por juicio de cinco expertos, tres oncólogos con experiencia y 2 enfermeras magistradas con experiencia en oncología infantil y alfa de Cronbach. Resultados: Después de la revisión y validación de los instrumentos cuantitativo y cualitativos por los 5 expertos, la calificación obtenida es una puntuación de muy confiable 94,9 para el instrumento cuantitativo y una puntación de muy confiable de 96 puntos, para el instrumento cualitativo. Los puntajes alcanzados dan la seguridad para estructura y proceso, por medio del Coeficiente Alfa de Cronbach y validez de contenido y de constructo. Conclusión: estos instrumentos, quedan validados por juicio de expertos como herramientas muy confiables para obtener datos que se requieran para la investigación científica(AU)

Acute lymphoid leukemia (ALL) is the most common cancer in children. Worldwide, it estimated that about 30% corresponds to all malignant neoplasms that occur in children and of these, more than 75% are ALL. For this reason, we saw the need to develop an instrument to measure factors that influence the diagnosis. Because a timely diagnosis contributes to improving the life rate of these patients. Objective: To validate instruments to measure the factors that influence lymphoblastic leukemia diagnosis in children. Methodology: This is a mixed investigation, exploratory cross-section. Descriptive non-experimental design. A pilot sample used to validate the quantitative instrument, with 15 parents or representatives of children diagnosed with acute lymphoblastic leukemia, selected and chosen in a probabilistic random way. For the qualitative instrument, a single mother of a child diagnosed with leukemia was used, validated by the judgment of five experts, three experienced oncologists and two magistrate nurses with experience in childhood oncology and Cronbach's alpha. Results: After the review and validation of the quantitative and qualitative instruments by the five experts, the score obtained is a very reliable score of 94.9 for the quantitative instrument and a very reliable score of 96 points for the qualitative instrument. The scores achieved provide security for structure and process, through Cronbach's Alpha Coefficient and content and construct validity. Conclusion: Expert judgment validated these instruments as very reliable tools to obtain data required for scientific research(AU)

Espondiloartrosis cervical e hipertrofia del ligamento amarillo / Cervical Spondyloarthrosis and Hypertrophy of the Yellow Ligament

RESUMEN Introducción: La espondiloartrosis cervical es una enfermedad articular crónica degenerativa, es la afección articular más frecuentemente observada en la población madura y una de las principales causas de discapacidad en todo el mundo, por lo que es importante el diagnóstico y tratamiento en las fases tempranas. Objetivo: Informar un caso clínico representativo de espondiloartrosis cervical e hipertrofia del ligamento amarillo. Presentación del caso: Paciente femenina de 49 años que seis años atrás sufrió una caída, y se golpeó el occipucio contra la pared, lo que le provocó pérdida transitoria del conocimiento y dolor en la región cervical; tres años después comenzó con limitación a los movimientos laterales del cuello, malestar y dolor sordo, referido a la nuca y al cuello. Conclusiones: El diagnóstico de espondiloartrosis cervical e hipertrofia del ligamento amarillo representa un desafío clínico, por lo poco común de la enfermedad a esta edad. El caso presentado es una paciente con alteraciones estructuradas en el esqueleto axial y gran repercusión anatómica y funcional debido a un relativo diagnóstico tardío, con evolución insatisfactoria. Por tanto, conviene conocer la enfermedad para realizar una detección precoz y ofrecer mejor atención terapéutica(AU)

ABSTRACT Introduction: Cervical spondyloarthrosis is a chronic degenerative joint disease, it is the most frequent joint condition in the mature population and one of the main causes of disability throughout the world, so diagnosis and treatment in the early stages are important. Objective: To report a representative clinical case of cervical spondyloarthrosis and hypertrophy of the yellow ligament. Case presentation: A 49-year-old female patient suffered a fall six years ago, hitting her occiput against the wall, causing her temporary loss of consciousness and pain in the cervical region. Three years later, she began with limitation of lateral neck movements, discomfort and dull pain, referred to the nape and neck. Conclusion: The diagnosis of cervical spondyloarthrosis and hypertrophy of the yellow ligament represents a clinical challenge, due to the rare nature of the disease at this age. The case reported is a patient with structured alterations in the axial skeleton and great anatomical and functional repercussions due to a relatively late diagnosis, with unsatisfactory evolution. Therefore, it is convenient to know the disease in order to early detect it and to offer better therapeutic care(AU)

Assessment of immunization among newborns: comparison between children delivered vaginally and by cesarean section

Background: Timely administration of vaccines, particularly for hepatitis B birth dose within 24 hours of birth is of immense importance. It is considered as an indicator of quality of immunization programme. This study aimed to assess effect of mode of delivery and type of hospital on immunization among newborns.Methods: This large multi-site study was conducted in Pune district having population of 9.43 million. A total of 13 hospitals were selected which included all government hospitals performing more than five cesarean sections per month, and one government and one private medical college hospital. Cesarean section and vaginally deliveries were enrolled in 1:1 ratio. Their children were followed till discharge. Data were collected by obstetrician or qualified nurse.Results: During study period 3,112 women were enrolled. The relative risk of not getting vaccine Hepatitis B birth dose before 24 hours among cesarean delivered newoborns was 1.08. The relative risk of not getting zero polio and BCG among cesarean delivered newborns was 0.71 and 0.76 respectively. All these differences were significant. The coverage for all vaccines was better in sub district hospitals than others. Coverage of all vaccines in government teaching hospital was better than private.Conclusions: Cesarean section enabled better coverage among newborns probably due to length of stay. Whereas the physical and mental stress after cesarean section resulted lesser coverage of hepatitis B birth dose within 24 hours. Opportunities of timely Hepatitis B birth dose administration were missed probably due to lack of knowledge among health workers about ideal timing.

Interconsultas de cuidados paliativos para pacientes con cáncer en un hospital general: Características y oportunidad / Interconsultation on palliative care for patients with cancer in a general hospital. Features and opportunity

Las recomendaciones internacionales apuntan a la integración temprana de cuidados paliativos (CP) en cáncer a través de la atención simultánea y del entrenamiento de los equipos primarios. La Unidad de CP del Hospital General de Agudos E. Tornú realiza interconsultas para pacientes internados en el hospital y brinda capacitación a los equipos tratantes. El perfil de las interconsultas realizadas podría brindar información importante sobre las características de la intervención de CP dentro de la institución. El objetivo de este estudio fue analizar retrospectivamente las interconsultas de primera vez de pacientes con cáncer realizadas a lo largo de 2 años, con foco en la temporalidad, la identificación de problemas por parte del equipo tratante y del equipo de interconsulta de CP, y la prontitud de respuesta y capacidad pronóstica de este último. La población atendida en interconsulta (168 casos) estuvo constituida principalmente por pacientes con enfermedad avanzada, deterioro del estado general, sin posibilidad de tratamiento oncológico y diagnóstico reciente. En aproximadamente 25% de los casos se encontraron indicios de intervención temprana y participación del equipo de CP en la toma de decisiones. Se discute la oportunidad de la intervención de CP y se señalan áreas con necesidad de mejora, como la identificación de síntomas no físicos y el pronóstico, a ser tenidas cuenta en las futuras actividades asistenciales y educativas.

The international recommendations point to the early integration of palliative care (PC) in cancer through simultaneous care and training of primary teams. The PC Unit of the Hospital General de Agudos E. Tornú conducts interconsultations for hospitalized patients in the hospital and provides training to the treatment teams. The profile of the interconsultations carried out could provide important information about the characteristics of the PC intervention within the institution. The objective of this study was to retrospectively analyze the first-time interconsultations of cancer patients carried out over 2 years, focusing on temporality, identification of problems by the treating team and the PC interconsultation team, the promptness of response and the prognostic capacity of the latter. In the period, 168 interconsultations were carried out. Most patients had advanced disease, poor performance status, no possibility of oncological treatment and recent diagnosis. In approximately 25% of the cases, evidence of early intervention and participation of the pc team in decision making was found. The opportunity of PC intervention is discussed and areas needing improvement are indicated, such as the identification of non-physical symptoms and prognosis, to be considered in future care and educational activities.

Assessment of timely immunization in an urbanized agglomeration of East Delhi, India

Background: The under-5 mortality rate in India has shown a decline in the last few decades. However, there is still a lot of work to be done for our country to achieve sustainable developmental goals. One of the factors contributing to child survival is immunization coverage, but high coverage does not mean timely vaccination. ‘On time’ immunization is an important yet little researched factor shielding a child from susceptibility to vaccine preventable diseases. This study aims at assessing the extent of timely immunization and predictors of intentional delay in vaccination of children.Methods: A cross-sectional study was conducted in East Delhi among caregivers having a child in the age group of 13-24 months. Sample size was calculated at 95% confidence limit and 3.5% absolute precision. The final sample size obtained was 350.Results: The percentage of fully and timely vaccinated children is 67.1%, whereas children fully vaccinated but with a delay of 4 weeks from the recommended age of administration is 19.7%. Partial vaccination was found in 11.2% of children and 2% of children were found to be not vaccinated. The most common reason for delay in immunization was pain at the time of administration leading baby cries and fear of needles (26.1%), followed by bad experience with previous vaccination (11.6%). Fear of side effects (14.5%) and being denied vaccination without card (11.6%) were other reasons.Conclusions: The immunization program should include timely completion of vaccination as a quality indicator. Delayed immunization can lead to epidemics in the community and threaten the goal of elimination of vaccine preventable diseases. Improving timeliness can be successfully achieved if the reasons for delay are taken into account.

Application of timely regional vascular occlusion in primary liver cancer resection / 国际外科学杂志

Objective To study the application effects of timely regional vascular occlusion in primary liver cancer(PLC) surgery. Methods Eighty-eight patients with PLC who underwent surgery in the Department of General Surgery of Yan'an University Affiliated Hospital from January 2014 to December 2016 were selected for prospective study, and they were divided into the experimental group and the control group by the random number table method, 44 cases of each group. In the experimental group, the blood supply was blocked with timely regional vascular occlusion while in the control group, the blood supply was blocked with half hepatic vascular occlusion. The occurrence of postoperative complications, and surgical indexes(surgical time, intraoperative blood loss, the time of hepatic portal occlusion, blood transfusion volume, abdominal drainage volume and hospital stay), levels of alanine aminotransferase, albumin and total bilirubin, levels of CD3+, CD4+, CD8+ and CD4 + /CD8 +, effective rate, control rate, and clinical efficacy were compared between the two groups. Measurement data with normal distribution were represented as (x) ± s and analyzed using the independent-sample t test between the two groups; within the groups, paired t-tests were used. Comparison of count data were represented as n(％ ), and analyzed using the chi-square test. Results The intraoperative blood loss, time of hepatic portal occlusion, blood transfusion volume and hospital stay of the experimental group were(331. 48 ±30.65) ml, (14.78土2.27) min, (132.61 ±13.87) ml, (9.29土1.19) d, and the control group were (500.61 ±50.62) ml, (23.96±2.89) min, (305.76 ± 30.64) ml, (12.10 ± 1.22) d, with statistically significant differences in above indexes between the two groups(all P< 0.05). The operation time and abdominal drainage volume in the experimental group were(146.86 ± 15.87) min and(321.77 ±33.65) ml respectively, while those in the control group were (143.07土15.35) min and(335.18 ±33.82) ml respectively, there was no significant difference between the two groups(P> 0.05 ). After surgery, the levels of alanine aminotransferase, total bilirubin and albumin of the experimental group were(54.86 ±5.61) U/L, (20.65 ± 2.32) U/L, (41.95土4.32) ng/ml, and the control group were(120.75 ± 13.03) U/L, (35.42+3.21) U/L, (70.25 ±7.45) ng/ml, with statistically significant differences in above indexes between the two groups(all P <0.05). After surg;ery, the levels of CD3 +, CD4+, CD8 + and CD4 + /CD8 + of the experimental group were 0.63 ±0.16, 0.52 ± 0.11, 0.20 ±0.04, 1.70 ±0.17 and the control group were 0.56 ±0.14, 0.45±0.12, 0.26 ± 0.05, 1.46土0.22, with statistically significant differences in above indexes between the two groups (all P< 0.05 ). There were no differences between the experimental group and the controlg roup in the response rate and the control rate(75.00％ vs.79.55％; 88. 64％ vs.90.91％ ) (P>0.05). Conclusions The application of timely regional vascular occlusion in PLC surgery can reduce the intraoperative blood loss, the time of hepatic portal occlusion, blood transfusion volume and hospital stay, improve the immune level and liver function. And there is no difference in response rate and control rate compared with half hepatic vascular occlusion, therefore it is worthy of clinical application.

Frecuencia de lesiones orales y variantes de lo normal en pacientes del Departamento de Estomatología de la Universidad Autónoma de Ciudad Juárez / Frequency of oral lesions and variants of the normal in patients from the Department of Stomatology, Autonomous University of Ciudad Juarez

Introducción: La exploración intraoral detallada es la clave en el diagnóstico temprano de lesiones potencialmente agresivas; de estamanera, se le ofrece al paciente un tratamiento adecuado y oportuno,reduciendo al máximo posibles complicaciones que pongan en peligrosu integridad y deterioren su calidad de vida. Objetivo: Determinar la frecuencia de lesiones y condiciones de la mucosa bucal en pacientes mayores de 18 años de la clínica de diagnóstico del Departamento de Estomatología de la Universidad Autónoma de Ciudad Juárez, Chihuahua...

Introduction: A detailed intraoral examination is key in the early diagnosis of potentially aggressive lesions; in this way, the patient isoff ered an adequate and timely treatment, reducing to the maximumpossible complications that could endanger his integrity and deterioratehis quality of life. Aim: To determine the frequency of lesions and conditions of the buccal mucosa in patients older than 18 years of the diagnostic clinic of the Department of Stomatology at the Autonomous University of Ciudad Juarez, Chihuahua...

A study on the immunization status of the left-behind children in the rural areas of Zhejiang Province / 预防医学

Objective To investigate the immunization status of the left-behind/non-left-behind children in the rural areas of Zhejiang Province. Methods Multi-stage cluster random sampling was adopted to recruit 0-6 years old children and their guardians in a rural mountainous county in Lishui District of Zhejiang Province. Household survey was conducted using structured questionnaires. Records of vaccination were obtained and verified in the local disease control and prevention center. Results A total of 420 questionnaires were issued, with a number of 416 were complete and valid. The Valid responsive rate was 99.05% . Among them, 97 were left-behind and 319 were non-left-behind children. The immunization coverage rates did not differ significantly between the left-behind and non-left-behind children. The timely immunization rates of the third shot of hepatitis B vaccine and the first shot of encephalitis vaccine differed significantly between left-and non left-behind children (P=0.049 and P=0.044, respectively) . Conclusion Immunization status of the left-behind children in the rural areas of Zhejiang province was in a good condition in general. The local disease control and prevention center should strengthen the communication, to promote immunization knowledge and to improve family supervision of the left-behind children.

Analysis of influencing factors of intra-laboratory turnaround time in emergency biochemistry tests / 国际检验医学杂志

Objective To investigate the intra-laboratory turnaround time(ILTAT) of the emergency biochemistry tests and to analyze the factors influencing ILTAT in order to adopt the corresponding improvement measures for perfecting the service quality and ensuring the patient medical safety.Methods ILTAT of the emergency biochemical specimens in our hospital from June to November 2015 was performed the retrospective statistics for comparing the determination timely rate between ILTAT≤60 min and ILTAT2 ≤120 min.ILTAT at different time periods in laboratory was emphatically analyzed.Results The determination timely rate of ILTAT ≤120min(ILTAT 1) was 98.8%(8638/8743),and which of ILTAT ≤60min(ILTAT 2) was 83.7%(7317/8743).The determination timely rate of ILTAT1 had no statistical difference among different time periods (χ2=3.36,P>0.05).The determination timely rate of ILTAT2 had statistical difference among different time periods(χ2=134.5,P<0.01).The determination timely rate of T 2(10:01-12:00) was highest (88.1%),which of T1 (8:01-10:00) was lowest(76.8%),which of T3(12:01-14:00) and T7 (6:01-8:00) was lower (79.4% and 80.2% respectively).Conclusion At present,ILTAT in our laboratory meets the requirements of the current regulations.Analyzing the ILTAT influencing factors in the emergency biochemistry,optimizing the workflow,improving the equipments and staffing allocation and improving the degree of information processing can further shorten the emergency biochemical ILTAT,and better meet the clinical and patient′s needs.

An etiological analysis of proptosis.

Background: The main objective of the study was to analyse the various causes for proptosis. Methods: A prospective analysis of 54 cases of proptosis. Detailed ocular and systemic history, examination and relevant investigations were done in necessary cases. Also other related specialties opinion obtained whenever indicated for diagnosis and treatment. Results: Out of 54 cases, 26 were axial and 28 were eccentric, 38 were unilateral, 16 were bilateral. Etiology of proptosis due to inflammation 20 cases, infectious 14 cases, neoplastic 10 cases, vascular 4 cases, traumatic 4 cases, others 2 cases. Conclusions: Thyroid eye disease is the single most common cause of proptosis in this study. Among neoplastic cases primary tumours were more common than secondary tumours in the orbit in this study. Orbital X-ray, B scan, CT scan and MRI were helpful in the diagnosis, treatment and follow up.

Construction of the Reporting System for Test Critical Values / 医学信息学杂志

The paper analyzes deficiencies in traditional manual screening of critical values , telephone notifications and manual record-ing of critical value reports , as well as problems existing in current critical value reporting systems in China .It designs a stable , timely and accurate reporting system for test critical values and mainly introduces the system design , system function and application features .

Oportunidade perdida para diagnóstico oportunista de diabetes mellitus em comunidades quilombolas do sudoeste da Bahia, Brasil / Missed opportunity for timely diagnosis of diabetes mellitus in Afrodescendant communities in the southwest of the state of Bahia, Brazil

O objetivo deste estudo foi estimar prevalência e fatores associados com oportunidade perdida para diagnóstico oportunista de diabetes (PDO) em comunidades quilombolas de Vitória da Conquista, Bahia. Trata-se de um estudo de corte-transversal de base populacional em amostra probabilística (n = 797). Para esta análise 548 indivíduos foram elegíveis considerando os critérios de risco: idade igual ou superior a 45 anos, índice de massa corporal elevado e hipertensão arterial. A prevalência de PDO foi estimada em 42,6%. Regressão logística demonstrou estarem estatisticamente associados, independentemente ao desfecho: autoavaliação de saúde boa/muito boa; não medir pressão arterial no último ano; não ter realizado consulta médica nos últimos doze meses; e, índice de acesso de serviços ruim. O elevado PDO apontado associou-se à baixa utilização e pior marcador de acesso aos serviços de saúde. Ações direcionadas ao diagnóstico e prevenção de DM devem priorizar populações de maior risco e incluir capacitação, treinamento das equipes de saúde da família e melhoria da estrutura e atenção nas unidades de saúde. Uma maior integração entre ações básicas de saúde e nível especia lizado pode impactar positivamente no diagnóstico precoce, e redução de possíveis complicações associadas a diabetes nesta população.

The scope of this study was to estimate the prevalence and associated factors of missed opportunities for timely diagnosis of diabetes mellitus in Afrodescendant communities in Vitoria da Conquista in the state of Bahia. It involved a population-based cross-sectional study based on a probability sample (n=797), where 548 individuals were eligible for analysis considering the risk criteria: age of 45 years old and above, increased Body Mass Index and hypertension. The prevalence of diabetes mellitus was estimated at 42.6%. Logistic regression indicated the following statistically associated factors: self-assessed good/very good health conditions; not measuring blood pressure and not consulting with a physician in the past twelve months; and poor access to health services. The high prevalence was associated with factors related to low utilization and poor access to health services. Actions for the diagnosis and prevention of diabetes should prioritize populations at risk, including better education and training of family health care teams, and improvement of attendance at health care units. Enhanced integration between primary and secondary health care actions can positively impact early diagnosis, treatment and reduction of potential complications associated with diabetes in this population.

Discussion on improving timely rate of medical equipment archives / 中国医学装备

Objective:To improve the medical equipment timely filing rate.Methods: Through the literature reference and practical work experience, based on the research of medical equipment archives management content, problems, solutions.Results: According to the comprehensive analysis of the literature in recent years is introduced and all levels of hospital medical equipment archives management and practice management work experience, summarizes the paper, summarized and further improve the management of medical equipment archives.Conclusion:To improve the timely filing rate, improve the utilization of archives, and find out the existing problems of hospital medical equipment archives management, the medical equipment archives play a major role in the practical work.

Estudio de la oportunidad en la administración de medicamentos anticonvulsivantes en un servicio de pediatria en Bogotá / Opportunity study drug administration anticonvulsants in a pediatric service in Bogota

El presente estudio, está enmarcado en la línea de investigación denominada Calidad en salud y enfermería de la Facultad de Enfermería de la Universidad Nacional de Colombia. Tiene como objetivo describir los elementos de estructura, proceso y resultado de la atención de enfermería relacionados con la oportunidad en la administración de medicamentos anticonvulsivantes en un servicio de pediatría de Bogotá. Es un estudio descriptivo con dos componentes: uno descriptivo univariado que permitió a partir de los hallazgos hacer una descripción de algunas variables de estructura, proceso y resultado que, desde la teoría, tienen relación con la administración de medicamentos, y el segundo componente descriptivo bivariado, permitió describir la relación entre la razón enfermero-a-paciente (variable de estructura) y la puntualidad en la administración de medicamentos (variable de proceso), a la vez que describir la relación entre cada una de las variables de estructura y proceso con la ocurrencia de eventos adversos (variable de resultado). La investigación se desarrolló en un servicio de hospitalización de una institución de tercer nivel de atención en Bogotá especializada en pediatría. La unidad de observación estuvo constituida por un periodo de 12 horas de tal manera que el día tenía dos periodos. Los datos se obtuvieron a través de la observación continua (24 horas), durante 150 periodos de tiempo, previa autorización de la institución. Se diseñó y utilizó un formato en el que se consignaron sistemática y ordenadamente los datos. Los resultados muestran que en términos de las variables observadas se cuenta con un protocolo disponible para la administración, hay buena disponibilidad de los medicamentos anticonvulsivantes y la razón paciente enfermero promedio es de 24:1. En proceso se encontró baja variabilidad del proceso, puntualidad en la administración de 1000 dosis e interrupciones ocasionadas fundamentalmente por llamadas telefónicas. En cuanto a resultado en el 62% de los turnos no se presentaron eventos convulsivos. Se encontró que no existe relación entre la razón paciente enfermero, con la variable puntualidad. No se encontraron correlaciones fuertes en los diferentes contextos entre las variables de estructura y proceso, con la variable de resultado "eventos convulsivos", sin embargo se evidenciaron correlaciones no nulas, aunque débiles.

This study is a contribution to the research line of health and nursing quality of the Nursing faculty at the National University of Colombia. Its purpose is to describe the elements of structure, process and outcome of nursing care related to the timing of anticonvulsant medication administration in a pediatric ward of Bogotá. It is a descriptive study with two components: one that allowed descriptive univariate findings from a description of some variables of structure, process and outcome, from the theory, are related to medication administration, and the second component bivariate descriptive, allowed to describe the relationship between nurse-to-patient ratio (variable structure) and timely medication administration (process variable), while describing the relationship between each of the variables of structure and process the occurrence of adverse events (outcome variable).The research took place in a tertiary care level pediatric hospital specialized located in Bogotá. The observation unit consisted of a period of 12 hours. The data were obtained through continuous observation (24 hours), along 150 periods, with the previous authorization of the institution. A format was designed and used to record and organize systematically the data. The results show that in terms of the observed variables has a protocol is available for administration, there is good availability of anticonvulsant medication and nurse-to-patient ratio averages 24:1. In process showed low variability of the process, timely administration of 1000 doses and disruptions caused mainly by telephone. As a result in 62% of shifts were not presented convulsive events. We found no relationship between the nurse-to-patient ratio, with variable punctuality. No strong correlations were found in different contexts between structure and process variables with the outcome variable "convulsive events", however non-zero correlations were evident, albeit weak.