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Rev. enferm. UERJ ; 28: e39729, jan.-dez. 2020.
Article in English, Portuguese | LILACS (Americas), BDENF | ID: biblio-1116093


Objetivo: identificar as principais causas de óbito entre adolescentes de 10 a 19 anos em um município no interior do estado do Rio de Janeiro. Método: estudo descritivo, exploratório de abordagem quantitativa, a partir do levantamento de dados em registros de óbitos do município de Rio das Ostras. O desfecho foi causa básica do óbito. Os dados foram processados no Programa R. Resultados: foram observados 84 (100%) óbitos, com maior prevalência entre adolescentes de 17 a 19 anos, 49 (58,3%), do sexo masculino, 71 (84,5%) e de cor parda, 38 (45,2%). As principais causas de óbitos foram homicídio/perfuração por arma de fogo, 35 (41,7%), e acidentes, 32 (38,1%). Conclusão: o reconhecimento dessa vulnerabilidade configura importante caminho para o enfrentamento e resolução desse grave problema, sobretudo municípios localizados longe de centros urbanos, parece muitas vezes esquecido, no que tange o cumprimento de estatutos e políticas públicas a favor desse grupo etário.

Objective: to identify the main causes of death among adolescents aged 10 to 19 years in a municipality in the state of Rio de Janeiro. Method: in this exploratory, descriptive, quantitative study, based on data collected from death records in the municipality of Rio das Ostras, the basic cause of death was the outcome. The data were processed in the statistics software, R. Results: of the 84 (100%) deaths observed, prevalence was higher among adolescents aged 17 to 19 years (49; 58.3%), males (71; 84.5%), and pardos (38; 45.2%). The main causes of deaths were firearm Injury / homicide (35; 41.7%) and accidents (32; 38.1%). Conclusion: one important step towards confronting and solving this serious problem is to acknowledge this vulnerability, especially in municipalities distant from urban centers, which often seem neglected as regards compliance with statutes and public policies in favor of this age group.

Objetivo: identificar las principales causas de muerte entre adolescentes de 10 a 19 años en un municipio del estado de Río de Janeiro. Método: en este estudio exploratorio, descriptivo, cuantitativo, basado en los datos recopilados de los registros de defunciones en el municipio de Rio das Ostras, la causa básica de la muerte fue el resultado. Los datos se procesaron en el programa estadístico R. Resultados: de las 84 (100%) muertes observadas, la prevalencia fue mayor entre los adolescentes de 17 a 19 años (49; 58.3%), varones (71; 84.5%) y pardos (38; 45,2%). Las principales causas de muerte fueron lesiones por arma de fuego / homicidio (35; 41.7%) y accidentes (32; 38.1%). Conclusión: un paso importante para enfrentar y resolver este grave problema es reconocer esta vulnerabilidad, especialmente en municipios alejados de los centros urbanos, que a menudo parecen descuidados en cuanto al cumplimiento de los estatutos y las políticas públicas a favor de este grupo de edad.

Humans , Male , Female , Child , Adolescent , Young Adult , Accidents/statistics & numerical data , Cause of Death , Vulnerable Populations/statistics & numerical data , Homicide/statistics & numerical data , Brazil , Epidemiology, Descriptive , Age Factors , Social Vulnerability , Mortality, Premature
Korean Circulation Journal ; : 395-405, 2020.
Article in English | WPRIM (Western Pacific) | ID: wprim-816678


Despite considerable efforts to prevent and treat cardiovascular disease (CVD), it has become the leading cause of death worldwide. Cardiac mitochondria are crucial cell organelles responsible for creating energy-rich ATP and mitochondrial dysfunction is the root cause for developing heart failure. Therefore, maintenance of mitochondrial quality control (MQC) is an essential process for cardiovascular homeostasis and cardiac health. In this review, we describe the major mechanisms of MQC system, such as mitochondrial unfolded protein response and mitophagy. Moreover, we describe the results of MQC failure in cardiac mitochondria. Furthermore, we discuss the prospects of 2 drug candidates, urolithin A and spermidine, for restoring mitochondrial homeostasis to treat CVD.

Adenosine Triphosphate , Cardiovascular Diseases , Cause of Death , Heart Failure , Heart , Homeostasis , Mitochondria , Mitophagy , Organelles , Quality Control , Spermidine , Unfolded Protein Response
Yonsei Medical Journal ; : 229-234, 2020.
Article in English | WPRIM (Western Pacific) | ID: wprim-811473


PURPOSE: This study was designed to provide a basis for building a master plan for a regional trauma system by analyzing the distribution of trauma deaths in the most populous province in Korea.MATERIALS AND METHODS: We investigated the time distribution to death for trauma patients who died between January and December 2017. The time distribution to death was categorized into four groups (within a day, within a week, within a month, and over a month). Additionally, the distribution of deaths within 24 hours was further analyzed. We also reviewed the distribution of deaths according to the cause of death and mechanism of injury.RESULTS: Of the 1546 trauma deaths, 328 cases were included in the final study population. Patients who died within a day were the most prevalent (40.9%). Of those who died within a day, the cases within an hour accounted for 40.3% of the highest proportion. The majority of trauma deaths within 4 hours were caused by traffic-related accidents (60.4%). The deaths caused by bleeding and central nervous system injuries accounted for most (70.1%) of the early deaths, whereas multi-organ dysfunction syndrome/sepsis had the highest ratio (69.7%) in the late deaths. Statistically significant differences were found in time distribution according to the mechanism of injury and cause of death (p<0.001).CONCLUSION: The distribution of overall timing of death was shown to follow a bimodal pattern rather than a trimodal model in Korea. Based on our findings, a suitable and modified trauma system must be developed.

Cause of Death , Central Nervous System , Hemorrhage , Humans , Korea , Wounds and Injuries
Article in English | WPRIM (Western Pacific) | ID: wprim-782510


Cancer is a major cause of death in dogs worldwide, and the incidence of cancer in dogs is increasing. The attenuated total reflection Fourier transform infrared spectroscopic (ATR-FTIR) technique is a powerful tool for the diagnosis of several diseases. This method enables samples to be examined directly without pre-preparation. In this study, we evaluated the diagnostic value of ATR-FTIR for the detection of cancer in dogs. Cancer-bearing dogs (n = 30) diagnosed by pathologists and clinically healthy dogs (n = 40) were enrolled in this study. Peripheral blood was collected for clinicopathological diagnosis. ATR-FTIR spectra were acquired, and principal component analysis was performed on the full wave number spectra (4,000–650 cm−1). The leave-one-out cross validation technique and partial least squares regression analysis were used to predict normal and cancer spectra. Red blood cell counts, hemoglobin levels and white blood cell counts were significantly lower in cancer-bearing dogs than in clinically healthy dogs (p < 0.01, p < 0.01 and p = 0.03, respectively). ATR-FTIR spectra showed significant differences between the clinically healthy and cancer-bearing groups. This finding demonstrates that ATR-FTIR can be applied as a screening technique to distinguish between cancer-bearing dogs and healthy dogs.

Animals , Cause of Death , Diagnosis , Dogs , Erythrocyte Count , Fourier Analysis , Incidence , Least-Squares Analysis , Leukocyte Count , Mass Screening , Methods , Principal Component Analysis
Article in English | WPRIM (Western Pacific) | ID: wprim-782225


Tuberculosis (TB) remains a threat to public health and is the leading cause of death globally. Isoniazid (INH) is an important first-line agent for the treatment of TB considering its early bactericidal activity. Resistance to INH is now the most common type of resistance. Resistance to INH reduces the probability of treatment success and increases the risk of acquiring resistance to other first-line drugs such as rifampicin (RIF), thereby increasing the risk of multidrug-resistant-TB. Studies in the 1970s and 1980s showed high success rates for INH-resistant TB cases receiving regimens comprised of first-line drugs. However, recent data have indicated that INH-resistant TB patients treated with only first-line drugs have poor outcomes. Fortunately, based on recent systematic meta-analyses, the World Health Organization published consolidated guidelines on drug-resistant TB in 2019. Their key recommendations are treatment with RIF-ethambutol (EMB)-pyrazinamide (PZA)-levofloxacin (LFX) for 6 months and no addition of injectable agents to the treatment regimen. The guidelines also emphasize the importance of excluding resistance to RIF before starting RIF-EMB-PZA-LFX regimen. Additionally, when the diagnosis of INH-resistant TB is confirmed long after starting the first-line TB treatment, the clinician must decide whether to start a 6-month course of RIF-EMB-PZA-LFX based on the patient's condition. However, these recommendations are based on observational studies, not randomized controlled trials, and are thus conditional and based on low certainty of the effect estimates. Therefore, further work is needed to optimize the treatment of INH-resistant TB.

Cause of Death , Diagnosis , Humans , Isoniazid , Public Health , Rifampin , Tuberculosis , Tuberculosis, Pulmonary , World Health Organization
Article in English | WPRIM (Western Pacific) | ID: wprim-787280


Cancer remains a leading cause of death, despite multimodal treatment approaches. Even in patients with a healthy immune response, cancer cells can escape the immune system during tumorigenesis. Cancer cells incapacitate the normal cell-mediated immune system by expressing immune modulation ligands such as programmed death (PD) ligand 1, the B7 molecule, or secreting activators of immune modulators. Chimeric antigen receptor (CAR) T cells were originally designed to target cancer cells. Engineered approaches allow CAR T cells, which possess a simplified yet specific receptor, to be easily activated in limited situations. CAR T cell treatment is a derivative of the antigen-antibody reaction and can be applied to various diseases. In this review, the current successes of CAR T cells in cancer treatment and the therapeutic potential of CAR T cells are discussed.

Antigen-Antibody Reactions , Carcinogenesis , Cause of Death , Cell- and Tissue-Based Therapy , Combined Modality Therapy , Humans , Immune System , Ligands , Receptors, Antigen , T-Lymphocytes , United Nations
Article in English | WPRIM (Western Pacific) | ID: wprim-811065


PURPOSE: The prevalence of asthma is increasing globally as the world population increases; however, and the prevalence and mortality of asthma have not been extensively investigated. Also, the effects of severity and aging on asthma prevalence and mortality are unknown. We aimed to investigate trends of the prevalence and mortality of asthma as well as health care uses and costs over 14 years according to disease severity by using real-world data in Korea.METHODS: Using the National Health Insurance Sharing Service database, we extracted asthmatic patients having diagnosis codes of asthma and prescription records of antiasthmatic medications from 2002 to 2015 and categorized them according to asthma exacerbation and regular treatment. We defined asthma-associated death in terms of patients' prescription records within 3 months before all-cause death, then linked with the Cause of Death Statistics. The annual asthma-related health care uses and costs were analyzed.RESULTS: The prevalence rates of asthma (1.6% to 2.2%) and severe asthma (SA; 3.5% to 6.1% among total asthmatics) have increased steadily over the decade in Korea, where the proportion of elderly asthmatics having increased. The asthma-related health care uses and costs had increased during the study period with the highest uses/costs in SA. The asthma mortality had a steady rising trend from 16.2 to 28.0 deaths per 100,000 with the highest mortality in SA.CONCLUSIONS: The prevalence and mortality of asthma as well as SA increases along with the burden of health care uses/costs. More active interventions, including changes in health care policies, are needed to reduce the prevalence and mortality of asthma, especially SA.

Aged , Aging , Asthma , Cause of Death , Delivery of Health Care , Diagnosis , Health Care Costs , Humans , Korea , Mortality , National Health Programs , Prescriptions , Prevalence
Article in English | WPRIM (Western Pacific) | ID: wprim-810956


BACKGROUND: The big data provided by Health Insurance Review and Assessment (HIRA) contains data from nearly all Korean populations enrolled in the National Health Insurance Service. We aimed to identify the incidence of facial fractures and its trends in Korea using this big data from HIRA.METHODS: We used the Korean Standard Classification of Disease and Cause of Death 6, 7 for diagnosis codes. A total of 582,318 patients were included in the final analysis. All statistical analyses were performed using SAS software and SPSS software.RESULTS: The incidence of facial fractures consistently declined, from 107,695 cases in 2011 to 87,306 cases in 2016. The incidence of facial fractures was the highest in June 2011 (n = 26,423) and lowest in January 2014 (n = 10,282). Nasal bone fractures were the most common, followed by orbit and frontal sinus fractures. The percentage of nasal bone fractures declined, whereas those of orbital fractures increased from 2011 to 2016 (P < 0.001). Among orbital fractures, inferior wall fractures were the most common, followed by medial wall fractures. Among mandibular fractures, angle fractures were the most common, followed by condylar process and symphysis fractures. Although it was difficult to predict the most common type of zygomatic and maxilla fractures, their incidence consistently declined since 2011.CONCLUSION: We observed trends in facial fractures in Korea using big data including information for nearly all nations in Korea. Therefore, it is possible to predict the incidence of facial fractures. This study is meaningful in that it is the first study that investigated the incidence of facial fractures by specific type.

Cause of Death , Classification , Diagnosis , Facial Bones , Fractures, Bone , Frontal Sinus , Humans , Incidence , Insurance, Health , Korea , Mandibular Fractures , Maxilla , Nasal Bone , National Health Programs , Orbit , Orbital Fractures
Rev. salud bosque ; 10(1): 1-14, 2020. Graf, tab, Ilus
Article in Spanish | LILACS (Americas), COLNAL | ID: biblio-1104435


Introducción. Según el Ministerio de Salud y Protección Social, las enfer-medades del sistema circulatorio fueron la primera causa de mortalidad en Colombia entre 2005 y 2014, dentro de las cuales la enfermedad isquémica cardiaca (EIC) representó el 49,30 % de los casos. Respecto a esta última, el Instituto Nacional de Salud indicó que ocupó el primer lugar en 2010 entre las causas de muertes en el país.Objetivo. Caracterizar la mortalidad por EIC en Bogotá, Colombia, en el periodo 2008-2015 bajo la perspectiva de las principales variables sociodemográficas.Materiales y métodos. Estudio descriptivo basado en fuentes secundarias. Se analizaron los casos de muerte por EIC en Bogotá para el periodo 2008-2015. Los datos demográficos se obtuvieron de las proyecciones poblacionales del Departamento Administrativo Nacional de Estadística (DANE) del censo del 2005. La caracterización de la mortalidad por EIC se hizo a partir del grupo 303 de la lista 6/67 de la Organización Panamericana de la Salud (OPS). Se tomaron las muertes codificadas como EIC con el código 3.03 y los códigos CIE-10: I20, I21, I22, I23, I24, I25. Las variables sociodemográficas estudiadas fueron sexo, edad, nivel educativo, afiliación al sistema de seguridad social y estado civil.Resultados. Entre 2008 y 2015 se registró un aumento del 14,56 % en la tasa de mortalidad por EIC en Bogotá, situación que coincidió con lo reportado por el DANE, quien indicó que para el 2015 esta enfermedad representó el 15 % de la mortalidad por todas las causas registradas en Bogotá.Conclusiones. Las variables sociodemográficas juegan un papel importante en la frecuencia de aparición de las enfermedades del sistema circulatorio, por lo cual se debe buscar intervención por parte del Estado para generar un mayor impacto en términos de mortalidad.

Introduction: According to the Colombian healthcare authority, cardiovascular diseases were the leading cause of mortality from 2005 to 2014. Among these, the cardiac ischemic disease (CID) represented 49.3% of the total reported cases and in 2010, it became the leading cause of death nationwide. Objectives: To characterize CID mortality in Bogota, Colombia, during 2008 ­ 2015, according to sociodemographic variables Materials & Methods: This is a descriptive study based on secondary sources. CID related deaths in Bogota were analyzed during the 2008-2015. Demographic data were collected from the 2005 National Population Census population projections The support for CID mortality characterization is found in Pan American Health Organization ́s Group 303, list 6/67, including ICD-10 codes I20, I21, I22, I23, I24, I25. The analyzed sociodemographic variables were: gender, age, education level, social security system affiliation, and civil status. Results: CID mortality rate in Bogota increased 14.56% during 2008-2015. According to the Colombian National Administrative Department of Statistics, CID represented 15% of all deaths causes in Bogota in 2015, supporting the findings of this study. Conclusion: Sociodemographic variables play an important role in the incidence of circulatory system diseases. The Colombian state should seek appropriate interventions at this level, to achieve a greater impact on mortality rate.

Introdução. Segundo o Ministério da Saúde e Proteção Social, as doenças do sistema circulatório foram as principais causas de mortalidade na Colômbia entre 2005 e 2014, as doenças cardíacas isquêmicas (CID) representaram 49,30% dos casos do total. Quanto a este último, o Instituto Nacional de Saúde indicou que ficou em primeiro lugar em 2010 entre as causas de morte no país. Objetivo. Caracterizar a mortalidade por EIC em Bogotá, Colômbia, no período de 2008 a 2015, sob a perspectiva das principais variáveis sociodemográficas. Materiais e métodos. Estudo descritivo, baseado em fontes secundárias. Foram analisados casos de morte por EIC em Bogotá no período de 2008 a 2015. Os dados demográficos foram obtidos das projeções populacionais do Departamento Administrativo Nacional de Estatística (DANE) do censo de 2005. A caracterização da mortalidade por EIC foi feita a partir do grupo 303 da lista 6/67 da Organização PanAmericana da Saúde (OPS). Foram registados óbitos codificados como EIC com os códigos 3.03 e CID-10: I20, I21, I22, I23, I24, I25. As variáveis sociodemográficas estudadas foram sexo, idade, escolaridade, afiliação ao sistema previdenciário e estado civil. Resultados. Entre 2008 e 2015, houve um aumento de 14,56% na taxa de mortalidade por EIC em Bogotá. Situação confirmada pelo DANE, que indicou que em 2015 esta doença representava 15% da mortalidade por todas as causas em Bogotá.Conclusões. As variáveis sociodemográficas desempenham papel importante na frequência do aparecimento de doenças do aparelho circulatório, motivo pelo qual a intervenção do Estado deve ser procurada

Humans , Cardiovascular Diseases , Myocardial Ischemia , Cardiovascular System , Incidence , Morbidity , Mortality , Cause of Death , Population Forecast , Colombia , Death
Rev. salud bosque ; 10(1): 1-10, 2020. Tab, Ilus, Graf
Article in Spanish | LILACS (Americas), COLNAL | ID: biblio-1104438


La tuberculosis (TB) es la enfermedad bacteriana infecciosa que más muertes causa en el mundo, panorama que puede empeorar debido a la drogorresistencia. La tuberculosis multidrogoresistente (TB-MDR), es decir la que presenta resistencia simultánea a isoniazida y rifampicina (principales fármacos antituberculosos), tiene una relevancia particular: de los 10 millones de personas que desarrollan TB anualmente, 458.000 presentan TB-MDR con un pronóstico mucho peor que el de los infectados por cepas sensibles. En el presente artículo se exploran los principales aspectos de la TB-MDR, haciendo énfasis en su tratamiento

Tuberculosis (TB) is the worldwide leading infectious cause of death and, the emergence of drug-resistant tuberculosis can only worsen the scenario. Multidrug-Resistant Tuberculosis (TB-MDR) has proven resistant to both isoniazid and rifampin, the main antituberculous drugs. Out of 10 million people developing TB annually, 458 000 exhibit TB-MDR, having worse prognosis than those infected by sensitive strains. Recently, new drug-resistant TB treatment guidelines were issued both by the World Health Organization and health authorities in Colombia. The present paper explores the main aspects of TB-MDR emphasizing s sanitary authorities also, new guidelines were published by Colombian minister of health and social protection. In this paper, the main aspects of TB-MDR are explored, especially those related to its treatment.

Tuberculosis, Multidrug-Resistant , Antitubercular Agents , Rifampin , Tuberculosis , Cause of Death , Colombia
Article in English | WPRIM (Western Pacific) | ID: wprim-786079


In type 2 diabetes (T2D), the leading cause of death is cardiovascular complications. One mechanism contributing to cardiac pathogenesis is alterations in metabolism, with the diabetic heart exhibiting increased fatty acid oxidation and reduced glucose utilisation. The processes classically thought to underlie this metabolic shift include the Randle cycle and changes to gene expression. More recently, alternative mechanisms have been proposed, most notably, changes in post-translational modification of mitochondrial proteins in the heart. This increased understanding of how metabolism is altered in the diabetic heart has highlighted new therapeutic targets, with an aim to improve cardiac function in T2D. This review focuses on metabolism in the healthy heart and how this is modified in T2D, providing evidence for the mechanisms underlying this shift. There will be emphasis on the current treatments for the heart in diabetes, alongside efforts for metabocentric pharmacological therapies.

Cause of Death , Gene Expression , Glucose , Heart , Metabolism , Mitochondrial Proteins , Protein Processing, Post-Translational
Article in English | WPRIM (Western Pacific) | ID: wprim-786076


Cardiovascular disease (CVD), which is the leading cause of death worldwide, is strongly affected by diet. Diet can affect CVD directly by modulating the composition of vascular plaques, and indirectly by affecting the rate of aging. This review summarizes research on the relationships of fasting, meal timing, and meal frequency with CVD incidence and progression. Relevant basic research studies, epidemiological studies, and clinical studies are highlighted. In particular, we discuss both intermittent and periodic fasting interventions with the potential to prevent and treat CVD.

Aging , Blood Pressure , Caloric Restriction , Cardiovascular Diseases , Cause of Death , Diet , Epidemiologic Studies , Fasting , Incidence , Meals
Med. leg. Costa Rica ; 36(2): 6-16, sep.-dic. 2019. tab
Article in Spanish | LILACS (Americas) | ID: biblio-1040441


Resumen El presente trabajo corresponde a una investigación de la lesionología y antecedentes personales de las personas que han muerto de manera suicida en Costa Rica de 2010 a 2016. De los 2174 autopsias de suicidios que se realizaron en la Sección de Patología Forense del Departamento de Medicina Legal del Organismo de Investigación Judicial de Costa Rica, tomando como fuente de información la base de datos del Sistema de Automatización de Patología Forense del Departamento de Medicina Legal, se extrajo una muestra de 353 y a estos se les investigó información adicional en expediente y otros registros de poder judicial para obtener información relacionada con antecedentes patológicos personales, antecedentes sociales y mayores detalles del suicidio. Además, según el tipo de lesión que produjo la muerte, se caracteriza el tipo de asfixia, la localización del nudo, el lugar de ingreso del proyectil de arma de fuego o el tipo de sustancia usada para el suicidio.

Abstract The present work corresponds to research of the lesionology and personal antecedents of people that have died in a suicidal way in Costa Rica from 2010 to 2016. From the 2174 autopsies of suicides that were realized in the Section of Forensic Pathology of the Department of Legal Medicine of the Judicial Investigation Organization of Costa Rica, taking as a source of information the database of the Forensic Pathology Automation System of the Department of Legal Medicine, a sample of 353 was extracted and additional information was researched in the forensic file and other records of judicial system to obtain information related to personal pathological background, social background and more details of suicide. In addition, depending on the type of injury that caused the death, the type of asphyxia, the location of the knot, the place of entry of the firearm projectile or the type of substance used for suicide are characterized.

Humans , Male , Female , Autopsy , Suicide/statistics & numerical data , Data Interpretation, Statistical , Cause of Death , Costa Rica
Pesqui. vet. bras ; 39(9): 686-695, Sept. 2019. tab, graf
Article in English | LILACS (Americas), VETINDEX | ID: biblio-1040742


We reviewed the records of 5,083 cattle necropsies performed from January 1995 to December 2018 and filed at the Laboratory of Anatomic Pathology (LAP) of the "Universidade Federal de Mato Grosso do Sul" (UFMS). These necropsies were performed either by LAP-UFMS faculty (22.33%) or by field veterinary practitioners (77.67%) who subsequently submitted material for histological evaluation at the LAP-UFMS. Conclusive diagnoses were reached in 46.21% of the protocols (2,349 cases), and approximately 65% of the cases were classified as inflammatory or parasitic diseases, with rabies being the most diagnosed disease (20.82% of total conclusive diagnosis). There were a large number of protocols in which the diagnosis was of nonsuppurative meningoencephalitis of unknown cause (NSMUC). Those were the main differentials for rabies and bovine herpesvirus-5 necrotizing meningoencephalitis (NME); that is, the number of rabies cases may be even higher if one considers that many cases of NSMUC might be undiagnosed rabies cases. Toxic and toxic-infectious diseases were the second most prevalent category, and botulism cases represented 41% of this category. The other categories corresponded to less than 20% of the total diagnoses and were distributed in decreasing order of frequency as degenerative diseases (9.79%), diseases caused by physical agents (3.87%), other diseases (2.13%), neoplasms and tumor-like lesions (1.79%), metabolic or nutritional disorders (1.75%) and congenital malformations (0.64%). The large number of inconclusive diagnoses was mainly due to improper conditions of mailed-in material for histopathological evaluation, namely, nonrepresentative samples of all organs, autolysis, and the absence of epidemiological and clinical-pathological information.(AU)

Em um levantamento sobre doenças de bovinos, revisamos os protocolos de 5.083 necropsias de bovinos realizadas no período de janeiro de 1995 a dezembro de 2018 e arquivados no Laboratório de Anatomia Patológica (LAP) da Universidade Federal de Mato Grosso do Sul (UFMS). Essas necropsias foram realizadas pelos veterinários e professores do LAP-UFMS (22,33%) ou por médicos veterinários de campo (77,67%) que, posteriormente, submeteram ao LAP-UFMS material para avaliação histológica. Diagnósticos foram conclusivos em 46,21% dos casos protocolados (2349), e aproximadamente 65% deles foram classificados como doenças inflamatórias ou parasitárias, sendo a raiva a doença mais diagnosticada (20,82% dos diagnósticos conclusivos). Havia um grande número de protocolos nos quais o diagnóstico era de encefalite/meningoencefalite não supurativa de causa indeterminada, para o qual os dois principais diferenciais são raiva e meningoencefalite necrosante por herpesvírus bovino; isso sugere que o número de casos de raiva pode ser ainda maior, se considerarmos que muitos destes podem ser casos de raiva não diagnosticados adequadamente. As doenças tóxicas e toxi-infecciosas foram a segunda categoria mais prevalente; dentre elas, os casos de botulismo compuseram 41%. As demais categorias corresponderam a menos de 20% do total de diagnósticos e foram distribuídas em ordem decrescente de frequência, em doenças degenerativas (9,79%), doenças causadas por agentes físicos (3,87%), outras doenças (2,13%), neoplasmas e lesões tumoriformes (1,79%), distúrbios metabólicos ou nutricionais (1,75%) e malformações congênitas (0,64%). O grande número de diagnósticos inconclusivos deveu-se principalmente às condições inadequadas do material enviado ao LAP-FAMEZ para avaliação histopatológica, ou seja, amostras não representativas de todos os órgãos, autolisadas ou acompanhadas de poucas de informações epidemiológicas e clínico-patológicas.(AU)

Animals , Cattle , Cattle Diseases/history , Retrospective Studies , Cause of Death , Brazil
Poblac. salud mesoam ; 16(2): 48-71, Jan.-Jun. 2019. tab, graf
Article in Spanish | LILACS (Americas) | ID: biblio-1091664


RESUMEN. Objetivo: Relacionar los datos de la tasa de mortalidad en la niñez por diarrea y gastroenteritis de presunto origen infeccioso o TMN A(090-099) con el Grado de Cohesión Social (GCS). Métodos: Es un estudio transversal y ecológico para el año 2015. La TMN A(090-099) municipal se calculó con los registros de defunciones del Sistema Nacional en Información en Salud (SINAIS). La aproximación hacia la cohesión social se hizo con base en el Consejo Nacional de Evaluación de la Política de Desarrollo Social (CONEVAL) a través del grado de cohesión social (GCS) municipal. Se calculó una correlación bivariada con la prueba de significancia de Spearman. Se obtuvo la correlación entre la TMN A(090-099) y el GCS. También se hizo un modelo: TMN A(090-099) variable dependiente confrontada con el GCS, el índice de Gini, el índice de rezago social y la no derecho habiencia. Resultados: Existe relación negativa entre el GCS y la TMN A(090-099), con significancia pero débilmente correlacionadas (- 0.320**); la hipótesis se acepta con reservas. El modelo presenta correlación moderada y positiva (R=0.554), la R cuadrada sugiere que el modelo explica casi el 27 % de los casos y el valor Durbin-Watson sugiere que el modelo cubre casi 90 % de los casos estudiados. Discusión: La cohesión social en Chiapas es muy tenue al hacer la aproximación que trató este trabajo. Los datos dan cuenta de que existen municipios con muy alta TMN A(090-099) y baja cohesión social, además de alto grado de rezago social; este escenario predomina, pero es necesario replantear la utilidad del abordaje cualitativo como recomendación encontrada en la literatura.

ABSTRAC. Objective: To relate the information of the childhood rate of mortality due to diarrhea and gastroenteritis of supposed infectious origin or TMN A(090-099) with the social cohesion degree (GCS). Methods: It is a transverse and ecological study for the year 2015. The municipal TMN A(090-099) was calculated with the National System in Health Information (SINAIS) deaths records. The approximation towards the social cohesion was done with the National Council for the Evaluation of the Social Development Policy (CONEVAL) through the municipal Social Cohesion Degree (GCS). A bivariate correlation was calculated with Spearman test. The correlation between the TMN A(090-099) and the GCS was obtained. Also a model was calculated: TMN A(090-099) as the dependent variable confronted with the GCS, Gini's index, social blacklog index and the lack of medical services. Results: A negative relation between the GCS and the TMN TO (090-099) was found, with significant but weakly correlation (-0.320 **); the hypothesis is accepted with reservations. The model presents moderate and positive correlation (R=0.554), the square R suggests that the model explains almost 27 % of the cases, and the Durbin-Watson value suggests that the model covers almost 90 % of the studied cases. Discussion: The social cohesion in Chiapas is very subdued. There are municipalities with very high TMN A(090-099) and lower social cohesion degree besides high social backlog degree; this scene prevails, but is necessary to restate the usefulness of the qualitative boarding as recommendation found in social cohesion literature.

Humans , Infant , Child, Preschool , Child , Child Care , Infant Mortality , Cause of Death , Social Cohesion , Mexico
Rev. pesqui. cuid. fundam. (Online) ; 11(3): 613-619, abr.-maio 2019. graf, tab
Article in English, Portuguese | LILACS (Americas), BDENF | ID: biblio-988044


Objetivo: Identificar os fatores sociodemográficos associados com a mortalidade de mulheres em idade fértil do Paraná nos períodos de 1996 e 2014. Método: Trata-se de um estudo ecológico transversal descritivo com dados coletados por meio do Sistema de Informação de Mortalidade e processados pelo teste de associação qui-quadrado. Resultados: Houve uma redução na prevalência de óbitos das mulheres em idade fértil nos períodos, de 17% para 13,2%, respectivamente. As principais causas de morte para ambos os períodos ocorreram por causas evitáveis sendo as principais causas básicas as causas externas, neoplasias, doenças cardíacas e do aparelho circulatório. Conclusões: Os resultados contribuíram para mostrar que as mortes de MIF são evitáveis a partir da introdução de medidas sociais e de diagnóstico e tratamento precoce. O padrão de mortalidade do estado é semelhante ao do país apontando necessidade de implementar ações nas três esferas de governo voltadas para a saúde da população feminina

Objective: The purpose has been to identify socio-demographic factors associated with mortality in women of reproductive age in the Paraná State from 1996 to 2012. Methods: It is a descriptive and cross-sectional study with an ecological approach. Data were collected through the mortality information system and processed by the Chi-square test for association. Results: There was a reduction in the prevalence of deaths in women of reproductive age over the period considered, from 17% to 13.2%, respectively. The leading causes of death for both periods occurred from preventable causes being the main underlying causes external ones, such as cancer, heart disease and circulatory system. Conclusions: The results supported that deaths in women of reproductive age are preventable with the introduction of social actions, as well as early diagnosis and treatment. The mortality pattern in the Paraná State is similar to the country, which points to the need of implementing actions towards all three government levels focused on the female population health

Objetivo: Identificar los factores sociodemográficos asociados a la mortalidad de las mujeres en edad fértil de Paraná entre 1996 y 2012. Método: Estudio ecológico descriptivo transversal, con los datos recogidos a través del Sistema de Información sobre Mortalidad y procesados por la prueba asociación Chi-cuadrado. Resultados: Hubo reducción en la prevalencia de las muertes de mujeres en edad fértil en el período, del 17% al 13,2%, respectivamente. Las principales causas de muerte para ambos períodos se produjo por causas prevenibles siendo principal causa subyacente causas externas, cáncer, enfermedades del corazón y el sistema circulatorio. Conclusiones: Las muertes del MIF son prevenibles con la introducción de medidas de carácter social y el diagnóstico y tratamiento tempranos. El estado del patrón de mortalidad es similar a la de la nation que señalan la necesidad de implementar acciones en los tres niveles de gobierno se centraron en la salud de la población femenina

Humans , Animals , Male , Female , Pregnancy , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Cause of Death/trends , Women's Health/statistics & numerical data , Population Studies in Public Health , Socioeconomic Factors , Mortality
Ocotal, Nueva Segovia; s.n; abr. 2019. 55 p. ilus, tab, graf, mapas.
Thesis in Spanish | LILACS (Americas) | ID: biblio-1015385


OBJETIVO. Caracterizar la mortalidad de mujeres en edad fértil de la Región Metropolitana del municipio del Distrito Central Francisco Morazán, Honduras, 2018. METODOLOGÍA: SE contó con un Universo y una muestra de 199 casos de defunciones en mujeres en edad fértil tomados de la base de datos de mortalidad de la Región Sanitaria Metropolitana. Se utilizó un instrumento que contenía las variables para cada una a desarrollar como: Rango de edad, Mes de fallecida, Causa de muerte según CIE10, Institución que notifica, Por clasificación territorial de violencia, Red a la que pertenece etc. RESULTADOS: Del total de las muertes de mujeres en edad fértil 39 (19.60%) corresponden a causas externas de morbilidad y de mortalidad, las neoplasias 31 (15.58%); enfermedades del sistema circulatorio 30 (15.08%), síntomas, signos y hallazgos anormales clínicos y de laboratorio, no clasificados en otra parte 18 (9.05%), Ciertas enfermedades infecciosas y parasitarias 14 (7.04%), las enfermedades del sistema respiratorio 13 (6.53%), los traumatismos, envenenamientos y algunas otras consecuencias de causa externa 12 (6.03%), las muertes por enfermedades del aparato digestivo 11 (5.53%), las enfermedades del aparato genitourinario 11 (5.53%); enfermedades endocrinas, nutricionales y metabólicas 10 (5.03%). CONCLUSIONES: La edad con mayor número de defunciones de las MEF estuvo comprendida entre los 20 y 49 años, la mayoría falleció en el mes de febrero, las causas más frecuentes de defunciones de MEF corresponden a causas externas de morbilidad y de mortalidad, de estas la principal es por heridas por arma de fuego

Humans , Female , Women , Mortality , Cause of Death , Fetal Death , Public Health , Epidemiology, Descriptive , Cross-Sectional Studies
Pesqui. vet. bras ; 39(3): 192-200, Mar. 2019. tab, ilus
Article in English | LILACS (Americas), VETINDEX | ID: biblio-1002795


Knowledge about the causes of death in felines constitutes important information to owners, veterinarians, and researchers, aiming at reducing the number of deaths in this species. In order to determine the main causes of death or euthanasia in cats in the Santa Catarina plateau, data from 1995 to 2015 available in necropsy files of the Laboratory of Animal Pathology (LAPA) of the State University of Santa Catarina (UDESC) were collected and evaluated. In that period, 1,728 cats were necropsied, mainly males (46.12%) and adults (50.11%). The mean ages at death for kittens, adults, and elderly were 5.07 months, 3.9 years, and 13.9 years, respectively. Of the 1,728 necropsy reports assessed, the cause of death was identified in 1,184 (68.52%) cases. The main cause of death was associated with infectious diseases (15.8%), with prevalence of feline infectious peritonitis (29.76%), followed by neoplasms (11.98%) with lymphoma (44.93%) and leukemia (16.91%) as the most common, and traumas (11.81%) mainly caused by motor vehicle accidents. These results show the need for owner awareness, as well as establishment of prophylaxis and vaccination programs, aimed at reducing the number of deaths and thus increasing life expectancy in the feline population.(AU)

O conhecimento a respeito da causa mortis em felinos é importante para que se construa um informativo para proprietários, médicos veterinários e pesquisadores, objetivando a redução no número de mortes na espécie. Com o intuito de determinar as principais causas de morte ou eutanásia em felinos domésticos no planalto catarinense foram avaliados os arquivos de registro das necropsias do período de 1995 a 2015 do Laboratório de Patologia Animal da Universidade do Estado de Santa Catarina. No período, foram necropsiados 1.728 felinos, principalmente machos (46,12%), adultos (50,11%). A idade média para filhotes foi de 5,07 meses, enquanto para adultos foi 3,9 anos e para idosos 13,9 anos. Das 1.728 necropsias de felinos, a enfermidade que levou o animal a morte foi determinada em 1.184 (68,52%). As doenças infecciosas foram a principal causa de morte (15,8%), dentre as quais a peritonite infecciosa felina (29,76%) foi a mais frequente; seguida das neoplasias (11,98%), sendo o linfoma (44,93%) e a leucemia (16,91%), as mais comuns; e dos traumatismos (11,81%), principalmente atropelamentos por veículos automotivos. Estes resultados refletem a necessidade da conscientização dos proprietários, bem como da instituição de programas de profilaxia e vacinação, visando a redução de mortes e o aumento na expectativa de vida para a população felina.(AU)

Animals , Cats , Cause of Death , Euthanasia, Animal/statistics & numerical data , Communicable Diseases/veterinary , Leukemia, Feline/mortality , Feline Infectious Peritonitis/epidemiology , Lymphoma/veterinary , Neoplasms/mortality