Long-term outcome (5-10 years) after non absorbable mesh insertion compared to partially absorbable mesh insertion for anterior vaginal wall prolapse repair

ABSTRACT Objective: To evaluate long-term (5-10 years) outcomes of Minimally Invasive Surgical (MIS) kit insertion with Prolift® (non-absorbable) mesh compared to the use of Prolift M® (partially absorbable), for anterior vaginal wall prolapse repair. Study design: In this retrospective study we compared women undergoing MIS kit Prolift® insertion (n=90) vs. Prolift M® insertion (n=79) for anterior vaginal wall prolapse repair between 2006 and 2012 at our Institution. A number of 169 women fulfilled the inclusion criteria and were included in the study. Results: During the study period 128 women (76%) completed full follow-up; of them 58 (73%) following MIS kit Prolift® insertion, and 70 (88%) following MIS kit ProliftM® insertion. There was no significant difference between the Prolift® and Prolift M® regarding parity (3.04 vs. 2.88, p=0.506), presence of hypertension (24.1% vs. 39.1%, p=0.088), diabetes mellitus (3.4% vs. 11.6%, p=0.109), or urinary stress incontinence (39.7% vs. 47.1%, p=0.475). All participants had been diagnosed with POP grade 3 or 4 before the procedure. No significant complications during the procedure or postoperative period were identified in the study groups. The follow-up period was at least five years in duration for both groups. Both groups were comparable according to questionnaires focused on function and satisfaction. Conclusion: Patients undergoing MIS kit Prolift® and Prolift M® insertion for anterior vaginal wall prolapse repair had comparable early and late postoperative outcomes. No differences in patient's function and satisfaction between the two groups were identified. According to our findings, there is no superiority to either of the two studied mesh devices.

Función sexual antes y después de la reparación quirúrgica del prolapso genital / Sexual function of women with genital prolapse before and after of surgical repair

Objetivo: comparar la función sexual (FS) de mujeres con prolapso genital (PG) antes y después de su reparación quirúrgica. Métodos: investigación de tipo comparativa y aplicada, con diseño cuasi experimental, prospectivo y de campo, donde se evaluó la FS de mujeres con diagnóstico de PG antes y después del tratamiento quirúrgico con técnicas convencionales, mediante el Cuestionario Sexual para Prolapso genital e Incontinencia Urinaria versión corta (PISQ-12). Resultados: al comparar la FS antes y después de la cirugía reparadora del PG, se determinó que tanto la puntuación total del PISQ-12 (15,90 +/- 6,51 vs. 32,17 +/- 3,62) como las puntuaciones de las dimensiones respuesta sexual (5,87 +/- 2,80 vs. 10,97 +/- 2,80) y limitaciones sexuales femeninas (4,88 +/- 3,90 vs. 16,77 +/- 3,00) fueron significativamente más altas luego de la intervención quirúrgica (p<0,001), a excepción del indicador intensidad del orgasmo (0,80 +/- 0,71 vs. 0,87+/- 0,73; p= 0,722) y la dimensión limitaciones sexuales de la pareja (4,37 +/- 2,14 vs. 3,56 +/- 2,70; p=0,815) donde sus puntuaciones antes y después del tratamiento quirúrgico no fueron estadísticamente significativas (p>0,05). Conclusiones: Lls mujeres con PG presentan una pobre FS, la cirugía reparadora del PG por técnicas convencionales mejoró significativamente la FS de las pacientes con disfunción del piso pélvico, permitiéndoles obtener a estas mujeres una vida sexual más placentera, con mejoría de su calidad de vida.

Objective: to compare sexual function (SF) of women with genital prolapse (GP) before and after surgical repair. Methods: this is a comparative and applied research with quasi-experimental, prospective and field design, which evaluated the SF of women diagnosed with PG before and after surgical treatment with conventional techniques, by the short version of the Prolapse and Incontinence Sexual Questionnaire (PISQ-12). Results: when comparing the SF before and after surgical repair of GP, it was determined that both the total score of PIQS-12 (15.90 +/- 6.51 vs. 32.17 +/- 3.62) and the scores of the dimensions: sexual response (5.87 +/- 2.80 vs. 10.97 +/- 2.80) and female sexual limitations (4.88 +/- 3.90 vs. 16.77 +/- 3.00) were significantly higher after surgery (p<0.001), except the indicator: orgasm intensity (0.80 +/- 0.71 vs. 0.87 +/- 0.73, p = 0.722) and the dimension partner's sexual limitations (4.37 +/- 2,14 vs. 3.56 +/- 2.70, p=0.815) where their scores before and after surgery showed no statistically significant differences (p>0.05). Conclusions: women with GP exhibit a poor SF, surgical repair of GP by conventional techniques significantly improves the SF of patients with pelvic floor dysfunction, allowing these women get sexual life more pleasant, which will impact on improving their quality of life.

Mallas protésicas en el tratamiento quirúrgico del prolapso genital en la mujer / Protesic meshes in the surgical treatment of the woman genital prolapse

El orígen del prolapso genital es multifactorial, actuando fundamentalmente en las estructuras del sostén pélvico. Las causas más frecuentes son la multiparidad, embarazos y partos con fetos macrosómicos, partos traumáticos, antecedente de cirugías previas del suelo pelviano y factores intrínsecos de la calidad de tejidos. Este daño tisular y en los ligamentos constituyen el orígen en la fisiopatología de la incontinencia urinaria, cistocele, rectocele e histerocele. Existen varias técnicas quirúrgicas para su reparación, sin embargo, los porcentajes de recidiva llegan hasta un 29 por ciento. Esto explica el por qué se está permanentemente investigando y realizando nuevos avances de refuerzo, como es el caso de la utilización de mallas protésicas, en que las estadísticas muestran un significativo beneficio y eficacia, que superan largamente a las otras técnicas cuando las indicaciones de uso son adecuadas. Al momento de elegir cuál utilizaremos, es importante el tamaño del poro y si es mono o multifilamento; ya que de estas características depende la potencial infección, biointegración y erosión de la vagina, como de órganos vecinos. La recidiva del cistocele reparado con malla polipropileno, macroporo monofilamento no supera el 3 por ciento, permitiendo asegurar que se trata de una técnica de mayor eficacia que las anteriores.

The Effect of Pelvic Organ Prolapse on Lower Urinary Tract Function

Pelvic organ prolapse (POP) is a process in which the pelvic contents, including the reproductive organ, bladder, rectum, and/or small intestines become herniated through defects in the vaginal wall. The pelvic organs are closely related to the urinary tract and thus various urinary functions can be affected. The purpose of this study was to evaluate the relationship between pelvic organ prolapse and lower urinary tract function by urodynamic studies. From March 1999 to May 2000, 40 patients with pelvic organ prolapse who underwent urodynamic studies (uroflowmetry, filling cystometry, urethral pressure profile) without barrier reduction of prolapse were analyzed. The majority of the cases of low grade POP involved patients with anterior wall prolapse, whereas the higher POP stages were more frequent in women with cervical cuff prolapse. Symptoms of stress urinary incontinence and hesitancy were more frequent in the patients with anterior wall prolapse. The urodynamic study showed a statistically significant increase in MUCP in patients with POP stage IV and the leading point of POP was cervical cuff. The subjective urinary symptoms of patients with POP appear to be less reliable as a diagnostic tool. POP had no adverse effect on the bladder storage function. However, POP affected the voiding function through an increase in MUCP, especially in patients with stage IV prolapse and when the leading point of POP was cervical cuff. Following the surgical correction of POP, an evaluation of the preoperative changes in the urodynamic study parameters should be performed.

Estudo radiológico da cúpula vaginal após histerectomia total: "cistografia fracionada" / Radiologicstudy of the vaginal post-hysterectomy total fragmented: \"fracitionated cystography\"

Raras se existentes, as análises estatísticas referentes as complicaçöes maiores e tardias das histerectomias totais - dispareunia, incontinência urinária, descenso da cúpula e prolapso vaginal - näo poderiam traduzir os resultados anatômo-topográficos - e por inferência funcionais e patológicos, ao par de uma concepçäo preditiva sobre a possível ocorrência destas patologias - que ocorrem ao nível da amputaçäo cérvico-vaginal e as conseqüentes repercussöes sobre as estruturas urogenitais remanescentes da regiäo. A cistografia fracionada demonstrou ser um método de imagem ideal para se estudar a altura do assoalho da bexiga e indiretamente da cúpula vaginal, a qualquer tempo ano pós-operatório da histerectomia, posto que ambas as estruturas permanecen em fixa continuidade. Ela reúne baixo custo, simplicidade, segurança, eficácia e fácil reprodutibilidade em centros médicos modestos. É efetiva e segura ferramenta para autocrítica dos procedimentos praticados pelos cirurgiöes e suas respectivas escolas, no particular. Para tanto foram estabelecidos três parâmetros - forma, posiçäo e altura - que interrelacionados sustentam o diagnóstico conclusivo. A fixaçäo da cúpula vaginal, nova variante técnica introduzida com o objetivo de fazer a profilaxia da ocorrência daquelas complicaçöes, realizada extra-peritonial e bilateralmente nos cotos intra-peritoniais dos ligamentos redondos, através dos espaços paramétricos e dos ligamentos largos abertos nos cursos da histerectomia, mantêm a mesma e o assoalho da bexiga - face a intrínseca continuidade de ambas - sempre elevados. Este procedimento é feito com a colocaçäo de um ponto em ambas extremidades laterais da cúpula vaginal, na altura do colo vesical e interessando os ligamentos cardial e útero-sacro, com um fio de lenta absorçäo medindo cinqüenta centímetros de comprimento. Subindo em seqüencia ele serve também para ligar a artéria uterina e ser fixado, finalmente, nos cotos dos ligamentos redondos. As análises estatísticas procedidas para a avaliaçäo de ambas as proposiçöes confirmam significativamente as afirmaçöes feitas de referência a cistografia fracionada e a técnica de fixaçäo da cúpula vaginal acima referidas.