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India, supporting 17% of the global population, from limited land (2.4% of the world's total) and freshwater resources (4%), faces severe water scarcity issues. The country experiences heightened challenges due to a monsoon climate leading to floods and droughts. Irrigation efficiency in India is 35-40% and irrigated area ~48.9%. To meet the demands of a large or growing population in limited land and water resources, climate-smart irrigation practices (CSIPs) are imperative. These practices not only increase yield but also precisely supply water, reduce water application volume, and enhance soil health under changing climate conditions. Precision water management technologies includes; advanced agro-techniques, micro-irrigation, conservation agriculture, crop diversification, integrated farming systems, and water harvesting. Micro-irrigation, encompassing drip and sprinkler systems, emerges as a critical solution for efficient water use. Techniques like Surface Drip Irrigation and Sub-surface Drip Irrigation (SSDI) not only save water but also enhance nutrient transport and reduce labor costs. The automation of micro-irrigation through sensors and wireless communication revolutionizes traditional practices, ensuring precise water management and boosting agricultural productivity. In addition, advanced agro-techniques, including laser land leveling, furrow-irrigated raised beds, aerobic rice cultivation, system of rice intensification, ground cover cum rice production system and Saguna rice technique have good potential to save water and improve water productivity. Implementing these advanced agro-techniques not only conserves water but also contributes to sustainable agriculture by improving overall water productivity, reducing environmental impact, and enhancing crop productivity. The integration of conservation agriculture (minimum soil disturbance, crop residue cover and crop diversification), integrated farming systems (combine diverse agricultural activities synergistically), and water harvesting is imperative for sustainable water management. This review paper systematically compiles climate-smart irrigation practices, including precision water management, combined with conservation agriculture, crop diversification, integrated farming systems, and water harvesting. This review paper offers researchers a comprehensive understanding of different CSIPs, assessing their impact on water conservation, increased crop and water productivity, and sustainability amid climate change. Farmers can gain practical understandings of CSIPs, while policymakers obtain essential information for addressing national water mission goals.
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Neolamarckia cadamba is a widespread medium-sized deciduous forest tree over most of India, Bangladesh, and Sri Lanka. Twenty-half-sib progenies of kadamb (Neolamarckia cadamba) from various regions in Bihar, Rajasthan, and Uttar Pradesh were sown in a glasshouse in 2022 in order to assess the genetic diversity using non-hierarchical Euclidean cluster analysis. Significant variation was seen in the biomass and morphological traits of a few plus trees. Under greenhouse conditions, significant differences were seen in the growth parameters of plus tree progenies. Six clusters were formed from the twenty NPTs, according to the genetic divergence analysis. Clusters V and VI were found to have the greatest inter-cluster distance (5.530). The cluster (4.258) displayed the highest intra-cluster distance. As a result, there was a genetic divergence between clusters. Therefore, in order to obtain high-yielding genotypes in Neolamarckia cadamba, hybridization involving trees of clusters VI and V is advised. Collar diameter was a major factor in the creation of genetic diversity and contributed the most to the overall divergence. The superior plus trees of cluster V (NPT4, NPT5, NPT11, NPT12, NPT13, NPT17) and cluster VI (NPT18, NPT19, NPT20) may be taken into consideration as possible parents for a future tree improvement program in Neolamarckia cadamba due to their high cluster mean and large genetic distance.
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The current research was conducted on twenty plus trees of Peltophorum pterocarpum from different locations in Bihar to study the association among different morphological and biomass traits. It was found that PPT12 (Rajgir Park) and PPT4 (Muraura, Nalanda) performed better for germination metrics under open field and greenhouse conditions, respectively. PPT6 (Nari, Nalanda) and PPT13 (Sathopur, Nalanda) outperformed all other superior tree progenies in terms of morphological and biomass attributes in green house and open field conditions, respectively. The phenotypic coefficient of variability was greater than the genotypic coefficient of variability for all morphological and biomass variables tested under green house and field conditions, showing that the environment played a greater role. Germination value heritability was found to be high in both environments. High heritability with high genetic advance was associated with shoot length in greenhouse condition, indicating additive gene action. Under greenhouse conditions, the phenotypic correlation coefficients among the seedling parameters evaluated varied from a non-significant 0.211 (P=0.01) between shoot root ratio and root dry weight and between shoot length and collar diameter to a very significant 0.967 (P=0.01).Accessions showing higher values for one or the other attributes could be selected as parents for further improvement.
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Background: Diabetes mellitus (DM) is a common metabolic disease. Anaemia is a common accompaniment to diabetes, particularly in patients with albuminuria or reduced renal function. Anaemia is more frequent and more severe at any level of glomerular filtration rate (GFR) in diabetics compared to nondiabetic patients. Methods: One hundred patients with type 2 diabetes mellitus were included in the study. Complete blood count, serum iron profile, ferritin, vitamin B12 and folate, kidney function tests and urine albumin creatinine ratio were assessed for these patients. Estimated glomerular filtration rate (eGFR) was calculated with MDRD-4 variable formula. Results: Fifty-four patients (54%) were found to be anaemic. Serum ferritin <50 µg/l was taken as cut off for defining iron deficiency anaemia. 21 patients had iron deficiency anaemia (IDA) and 33 had anaemia of chronic disease (ACD). Serum vitamin B12 and folate levels were within normal limits in all the patients. There was a rise in the prevalence of anaemia from 25.9% in patients with a normal ACR to 59.2% in those with microalbuminuria and to 75% in macroalbuminuria. Conclusions: Any degree of renal impairment and albuminuria are the risk factors for anaemia in these patients. Hence screening, characterization and treatment of aneamia in type 2 DM may be helpful in management of these patients.
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Background: Breast self-examination involves the women herself looking at the mirror and feeling each breast for possible lumps and distortion or swelling. It is seen that more than 10% to 20% breast cancer is detected by breast self-examination. Methods: A descriptive cross-sectional study was conducted to assess knowledge regarding breast self-examination among middle aged women in a selected community setting of Uttarakhand. A total of 62 samples were selected through systematic randomized sampling technique. A structured knowledge questionnaire was administered through interview technique to assess the knowledge. Results: Most of the (49%) women had poor knowledge regarding breast self-examination. There was significant association between age of the samples, education status, family income and previous information regarding breast self-examination with knowledge score. Conclusions: The study concluded that there was inadequate knowledge regarding breast self-examination among middle aged women in Uttarakhand. There is a need for educational programs to create awareness and improve knowledge regarding routine breast self-examination.
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IgG4-related sclerosing mesenteritis is a rare disease of mesentery of an unknown etiology which shows a constellation of histopathologic findings of lymphoplasmacytic inflammation with IgG4-positive plasma cells and marked fibrosis. This chronic inflammatory condition of mesentery forming an abdominal cocoon has never been described before to the best of our knowledge. Here, we report a patient with a history of subacute small bowel obstruction who was found to have an intra-abdominal encapsulating mass in the right iliac fossa and was finally diagnosed as IgG4-related sclerosing encapsulating peritonitis (abdominal cocoon) based on peroperative findings, histology and immunohistochemistry.
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Introduction: Body mass index (BMI) has traditionally been the chosen indicator by which to measure body size, composition, and to diagnose underweight and overweight. However, alternative measures that reflect abdominal adiposity, such as waist circumference, waist–hip ratio and waist–height ratio, have been suggested as being superior to BMI in predicting cardio-vascular diseases (CVD) risk. This study was aimed at determining the predictive power of anthropometric indicators like body mass index, waist circumference and waist stature ratio with body fat in an Indian military personnel population group, and to establish cut-off points as discriminators of high body fat. Methods: The study was crosssectional in nature with a sample size of 388 active Gorkha male personnel aged 20-49 years (mean age 33.1±5.33). Anthropometric indicators included body mass index, waist circumference, waist-hip ratio and waist-stature ratio. The analysis of receiver operating characteristic curves (ROC) with a confidence interval of 95% was adopted to identify predictors of obesity. Subsequently, the cut-off points with their relevant sensitivities and specificities were identified. Result: Areas under the ROC curves with 95% confidence intervals were body mass index = 0.86 (0.84-0.88); waist circumference = 0.82 (0.80-0.84); waist- hip ratio = 0.74 (0.71-0.77); waist-stature ratio = 0.81 (0.78-0.84). Different cut-off points of anthropometric indicators with better predictive power and their relevant sensitivities and specificities were identified. The following cut-offs with their corresponding sensitivity and specificity values are suggested for determining obesity for the study population: body mass index= 23.4 (98.00, 62.00), waist circumference= 77.8 (98.00, 60.50) and waist stature ratio= 0.47 (98.60, 68.00) respectively. Conclusion: The results showed that among active military personnel, BMI, WC and WSR may serve well in classifying individuals into broad categories corresponding to percentage fat categories. Further studies on different populations should be undertaken for the verification of the cut-off levels identified.
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The study was carried out to determine the seasonal variation of nitrite levels in drinking and surface waters of urban, peri-urban and rural areas of Lucknow, during 2007-2008, and to evaluate the nitrite removal and accumulation potential of certain native aquatic macrophytes. Most of the drinking and surface water samples were collected from urbanized region of the city. All drinking water samples detected, showed higher nitrite level in winter, when compared with that in summer and rainy seasons. However, in drinking water samples nitrite level was below the permissible limit i.e. 3.29 mg l-1 NO2. The surface water showed more than 3 fold higher levels of nitrite over the permissible level i.e. 0.06 mg l-1, and the level was higher during rainy season than in summer and winter seasons. Eight macrophytes viz. Peltandra virginica, Utricularia vulgaris, Eichhornia crassipes, Trapa natans, Mimulus glabratus, Marsilea quadrifolia, Pistia stratiotes and Polygonum persicaria were studied for phytoremediation potential of nitrite from the water under simulated laboratory conditions. The gradual diminution in the level of nitrite in the water and simultaneously it’s increase in the plant tissues was recorded at 5th, 10th and 15th d after plant culture. All the plants selected, removed nitrite from water but Polygonum persicaria, Mimulus glabratus, Trapa natans and Pistia stratiotes were found more efficient and removed nitrite upto 60.91, 58.09, 60.97 and 72.28%, respectively. Observations revealed that Pistia stratiotes can be used for the effective removal of nitrite from the contaminated water.
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Aedes , Animais , Ponte de Artéria Coronária , Ponte de Artéria Coronária sem Circulação Extracorpórea , Dengue/complicações , Dengue/transmissão , Vírus da Dengue , Edema/etiologia , Edema/fisiopatologia , Hidratação , Humanos , Índia , Masculino , Pessoa de Meia-Idade , Contagem de Plaquetas , Complicações Pós-Operatórias/fisiopatologia , Complicações Pós-Operatórias/terapia , Trombocitopenia/etiologia , Trombocitopenia/terapiaRESUMO
Antiphospholipid antibody syndrome (APLAS) characterises a clinical condition of arterial and venous thrombosis associated with phospholipids directed antibodies. APLAS occurs in 2% of the general population. However, one study demonstrated that 7.1% of hospitalised patients were tested positive for at least one of the three anticardiolipin antibody idiotype. Antiphospholipid antibodies often inhibit phospholipids dependent coagulation in vitro and interfere with laboratory testing of hemostasis. Therefore, the management of anticoagulation during cardiopulmonary bypass can be quite challenging in these patients. Here, we present a case of right atrial mass removal and pulmonary thrombectomy in a patient of APLAS.
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Adulto , Anestesia/métodos , Síndrome Antifosfolipídica/cirurgia , Ecocardiografia Transesofagiana , Feminino , Átrios do Coração , Humanos , Artéria Pulmonar/cirurgia , Embolia Pulmonar/cirurgia , TrombectomiaRESUMO
Plasmodium falciparum infections are frequently fatal if untreated and hence need to be diagnosed and treated early. Malaria diagnosis, with conventional Giemsa staining as a gold standard, has had several limitations. New rapid and accurate methods are needed for diagnosis. In this study, polymerase chain reaction (PCR) analysis specific for diagnosis of P. falciparum was evaluated. For the study, blood samples were collected from 310 patients suspected of having malaria. PCR analysis for P. falciparum from venous blood and at the same time Giemsa staining of thick and thin blood smears was done. A total of 160 (51.6 %) samples were positive for malarial parasite of which 63 (39.4 %) were positive for P. falciparum by Giemsa staining while 61 (38.1 %) were positive for P. falciparum by PCR analysis. Giemsa staining was time consuming, laborious and may give poor results in cases with low parasitaemia. The PCR analysis for P. falciparum was able to detect 3 cases of low parasitaemia missed initially on Giemsa staining, was 96.8 % sensitive, 100% specific but was very costly, needed a lot of practice and standardization and was time consuming. PCR analysis can be used to supplement the conventional Giemsa staining for reliable diagnosis of falciparum malaria especially in cases with low parasitaemia.
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Animais , DNA de Protozoário/química , Humanos , Índia , Malária Falciparum/sangue , Plasmodium falciparum/genética , Reação em Cadeia da Polimerase/economia , Sensibilidade e EspecificidadeRESUMO
PURPOSE: To evaluate the prognostic relevance of tumor size as determined on Magnetic Resonance Imaging (MRI) in cervical cancer. METHODS AND MATERIALS: A total of 70 consecutive patients were included in the study. 15 patients underwent surgery alone (Group A), 27 patients underwent surgery followed by adjuvant radiation (Group B), 14 patients underwent concomitant chemo radiation (Group C), and 14 patients underwent radical radiation alone (Group D). External radiation was delivered followed by intra cavitary brachytherapy. Serial MRI scans were performed in all patients before and after completion of treatment on a 1.0 Tesla MRI scanner. Patients were divided into three groups based upon MR volumes 100 cc. A correlation between MR volume, FIGO stage, disease free survival (DFS) and overall survival (OS) was done. Disease free and overall survivals were calculated using Kaplan Meier survival curves according to stage, MR volume and treatment protocol. RESULTS: In group I (MR volume 100 cc), 57% patients had stage II, 14% had stage III and 29% patients had stage IV disease. The DFS and OS did not achieve a level of statistical significance when evaluated as per protocol [DFS at p = 0.0685 and OS p = 0.3242], however a statistical significance was seen when DFS and OS were evaluated according to MR volumes [DFS, p = 0.0015 and OS, p = 0.0001]. CONCLUSION: In cervical cancer, the volume of disease as assessed on MRI may be a better prognostic indicator than FIGO staging and needs further evaluation.
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Adulto , Idoso , Idoso de 80 Anos ou mais , Intervalo Livre de Doença , Feminino , Humanos , Imageamento por Ressonância Magnética/métodos , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Prognóstico , Neoplasias do Colo do Útero/diagnósticoRESUMO
Conventional Giemsa stained peripheral blood smear examination for demonstration of malarial parasites remains the gold standard for diagnosis of malaria in developing endemic countries. However this technique is time consuming, requires training and may give poor results in cases with low parasitaemia. To overcome these problems and improve diagnostic accuracy two newer tests have been studied and compared with standard Giemsa staining. These are the wet mount fluorescence microscopy of Acridine Orange stained thin blood films (A.O.) and the Quantitative Buffy Coat technique (Q.B.C) for diagnosis of malaria. A.O. staining was found to be 97.5% sensitive and 100% specific for detection of all stages and species of malarial parasite. The Q.B.C assay was found to be 100% sensitive and 97.5% specific for diagnosis of malaria. A.O. staining was very fast and the species identification was easy once the staining was optimised. The Q.B.C. test required considerable amount of practice, costly equipment, however it was fast and in our study was found to be highly sensitive.
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Laranja de Acridina/diagnóstico , Corantes Azur/diagnóstico , Corantes/diagnóstico , Humanos , Índia , Malária Falciparum/sangue , Malária Vivax/sangueRESUMO
Although there are many causes of ulcer disease in postoperative period, hypoperfusion during cardiopulmonary bypass and advanced age are two key causes. We came across two cases of peptic ulcer perforation after coronary bypass graft surgery where these two common factors were absent. We have discussed various aetiolofical factors responsible for genesis of gastrointestinal ulcers in patients undergoing cardiac surgery using cardiopulmonary bypass.
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Adolescente , Antidiscinéticos/administração & dosagem , Carbidopa/administração & dosagem , Ritmo Circadiano/fisiologia , Dopaminérgicos/administração & dosagem , Combinação de Medicamentos , Distonia/complicações , Feminino , Seguimentos , Humanos , Levodopa/administração & dosagem , Vitiligo/complicaçõesRESUMO
OBJECTIVES: To provide the clinical profile and assess the significance of various risk factors contributing to the occurrence of oral candidosis in newborns. DESIGN: Case-control study. SETTING: Neonatal Intensive Care Unit (NICU). SUBJECTS: Twenty newborns with oral candidosis and an equal number of age and weight matched controls. INTERVENTIONS: All cases of oral candidosis were treated with local application of 1% Clotrimazole. RESULTS: Oral candidosis was documented in 3.2% (20/650) cases in the NICU. Acute pseudomembranous candidosis was the most common presentation. The mean age of onset was 10.5 days. Candida albicans was isolated in 50% cases in addition to C. tropicalis, C. paratropicalis, C. krusei, C. glabrata and C. parapsilosis. On univariate analysis, male sex, birth asphyxia and prolonged antibiotic therapy had a significant correlation with occurence of oral candidosis in neonates. Out of these, birth asphyxia was the only factor significantly associated with oral candidosis (OR 8.09, 95% CI 1.34-48.8, p = 0.0226) on multivariate analysis. CONCLUSIONS: C. albicans was the predominant isolate in this series of oral candidosis. Clinical manifestations were evident in the second week of life and birth asphyxia was the most important associated perinatal event.
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Antifúngicos/uso terapêutico , Candidíase Bucal/epidemiologia , Estudos de Casos e Controles , Países em Desenvolvimento , Feminino , Humanos , Hospedeiro Imunocomprometido , Incidência , Índia/epidemiologia , Recém-Nascido , Doenças do Recém-Nascido/epidemiologia , Unidades de Terapia Intensiva Neonatal , Modelos Logísticos , Masculino , Fatores de RiscoRESUMO
To evaluate the effects of P. amarus on hepatitis B virus (HBV) antigens and HBV-DNA, initial ethanolic extract and subsequent fractions of the plants were prepared. The whole plant material was dried, powdered and extracted with alcohol and subsequently fractionated in hexane, chloroform, butanol and finally in water. All the material were tested for in vitro effects on HBsAg, HBeAg and HBV-DNA in serum samples positive for HBV antigens followed by the screening of respective antigens by Elisa. HBV-DNA was determined by molecular hybridization. The extracts were effective against HBV antigens, the butanol extract being the most potent. Further chromatographic fractions showed an enhanced activity. The active fractions inhibited the interaction between HBsAg/HBeAg and their corresponding antibodies suggesting anti-HBs, anti-HBe-like activity and also an effect on HBV-DNA.
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DNA Viral/sangue , Antígenos de Superfície da Hepatite B/sangue , Antígenos E da Hepatite B/sangue , Vírus da Hepatite B/efeitos dos fármacos , Humanos , Extratos Vegetais/farmacologiaRESUMO
Rice long repetitive DNA (9-20 kbp) reassociating at Cot 50 M.s was cloned in pBR325. Out of several recombinants (Camr Ampr Tets), only a few were selected randomly for further characterization. The insert size in all these clones was 3-4 kbp. Restriction enzyme analysis showed the absence of EcoRI and BclI sites, presence of a single PstI and PvuII site and multiple sites for AluI in 3 clones namely pRLl, pRL7 and pRL10. The BamHI-PstI fragment of about 0·4 kbp in the pRL7 insert DNA (pRL7-0·4 kbp) was subcloned in M13mpl8 and partially sequenced using Sanger’s dideoxynucleotide chain termination method. Dot matrix comparison of this sequence with rice rDNA sequences revealed low homology with the 25S rDNA sequence of rice, however, hybridisation did not indicate any homology.
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Picroliv (active principle from Picrorrhiza kurroa), its major components picroside I, catalpol, kutkoside I, kutkoside, andrographolide (active constituent of Andrographis paniculata), silymarin and Phyllanthus niruri extract were tested for the presence of anti hepatitis B virus surface antigen (anti HBs) like activity. HBsAg positive serum samples obtained from hepatitis B virus (HBV) associated acute and chronic liver diseases and healthy HBsAg carriers were used to evaluate the anti-HBs like activity of compounds/extract. The latter were mixed with serum samples and incubated at 37 degrees C overnight followed by HBsAg screening in the Elisa system. A promising anti-HBsAg like activity was noted in picroliv (and its major components) catalpol, P. niruri which differed from the classical viral neutralization. Picroliv also inhibited purified HBV antigens (HBsAg and HBsAg) prepared from healthy HBsAg carriers. The in vitro testing system appears to be a suitable model to identify an agent active against HBV, prior to undertaking detailed studies.