Risk assessment of hearing loss of workers caused by urban rail transit noise / 中国职业医学

@#Abstract: Objective Methods Toevaluatetheriskofhearinglosscausedbyworkplacenoiseinurbanrailtransitenterprises. Noiseexposedworkers from eight rail transit lines in an urban rail transit enterprise was selected as the research subjects - usingconvenientsamplingmethod.Thenoiseintensitywasdetected,andtheriskofnoise inducedhearinglosswaspredictedby Results the method of the International Organization for Standardization. The incidence of noise exceeded the standard detection points was 8.3% (175/2 101) from 2016 to 2018. For risk classification in interval tunnel repairmen, higher risk was predictedattheageof40yearsoldandwiththelengthofserviceof20years,andhighriskwaspredictedattheageof50or60 yearsoldwiththelengthofserviceof30or40years.Theriskclassificationofstationinspectoratthepredictedageof 50years oldandthepredictedageof30yearswasnegligible,anditwasacceptableatthepredictedageof60yearsoldandthepredicted ageof40years.TheriskgradesofmaintenanceworkersinvehicledepotundertheabovetwopredictedconditionsweremediumConclusionrisk,whiletheriskclassificationofdriversunderwasacceptablerisk.Therailtransitenterprisehasacertain degreeofnoisehazardsintheoperationprocess.Theriskanddegreeofhearinglosscausedbynoiseincreaseswiththeincrease ofthelengthofservice.

Variation in oxidative injury markers in workers with occupationalnoise-induced hearing loss / 中国职业医学

@#Abstract: Objective - To explore the changes of oxidative damage indicators in workers with occupational noise induced （ ）， Methods hearingloss ONHL andtoscreenpossiblebiomarkersofONHL. Atotalof288maleworkersexposedtonoisein a large machinery maintenance enterprise were selected as the research subjects using the method of judgment sampling. After ， pure tone hearing threshold test they were divided into hearing loss group and normal hearing group according to the hearing ∶ ， ， ， loss and 1 1 pairing design of type of work age length of service with 144 people in each group. The activities of total （ - ）， - （ - ）， （ - ）， superoxidedismutase T SOD copper zincsuperoxidedismutase CuZn SOD manganesesuperoxidedismutase Mn SOD - （ ） （ ） Results glutathione S transferase GST and catalase CAT in serum of workers of the two groups were measured. The ， - ， - activitiesofGST T SOD Mn SOD and CAT in workersofthe hearing lossgroup were lowerthan those in the normalhearing （ P< ） ∶ group all 0.05 . The 1 1 logistic regression analysis of paired conditions showed that there was an association between ， - ， （ P< ） ONHL and activities of GST Mn SOD and CAT in serum all 0.05 after controlling the effects of smoking and drinking. ， - ， - ThehighertheactivitiesofGST Mn SODandCAT thelowertheriskofONHL.TheactivityofCuZn SODwasnotassociated （P ）Conclusion ， - withONHL >0.05 . TheactivitiesofserumantioxidantenzymessuchasGST Mn SODandCATarerelatedto ONHL.ThoseantioxidantenzymescanbeusedaseffectivebiomarkersforONHLworkers.

Kurtosis assessment of high frequency hearing loss caused by complex noise / 中国职业医学

@#Abstract: Objective To investigate the feasibility of kurtosis in evaluating high frequency hearing loss (HFHL) caused by Methods - complex noise. A total of 273 noise exposed workers in three metal tool manufacturing enterprises were chosen as studysubjectsusingajudgementsamplingmethod.Thenoiseintensityandkurtosisintheworkplacewasmeasured.Cumulative noiseexposure(CNE)wascalculatedfromnoiseintensityandworkingageandtheCNEwasadjustedusingkurtosis(CNE′).CNEResultsandCNE′wereusedtoevaluatetheriskofHFHL,andtheeffectsofthetwomethodswerecompared.ThemedianandMPP25,75percentiles[(25,75)]ofnoiseexposedintensityinthestudysubjectswas91.9(88.3,97.3)dB(A),andtheincidenceofMPPnoiseexposureexceededthenationaloccupationalexposurelimitaccountedfor81.0%.The(25,75)ofthekurtosiswas8.3 (7.9, 27.3), and kurtosis>4.0 accounted for 100.0%. The detection rate of HFHL was 39.6% (108/273). The detection rate of P - - HFHL increased with the increase of CNE and CNE′ (all <0.01). The goodness of fit of CNE′ in assessing the risk of HFHL Conclusion detectionwasbetterthanthatofCNE(coefficientsofdeterminationwere0.91and0.83,respectively). Kurtosiscan beusedasanauxiliaryparametertoadjusttheCNEandthenappliedtoevaluatetheriskofHFHLcausedbycomplexnoise.Keywords:Hearingloss;Noise;Strength;Kurtosis;Cumulativenoiseexposure;Riskassessment

Study on the relationship between PMCA2 polymorphism and susceptibility to noise-induced hearing loss / 中国职业医学

@#Abstract: objective 2+- Toinvestigatethecorrelationbetween geneticpolymorphismofplasmamembraneCa ATPaseisoform2 PMCA2 - Methods ( )andsusceptibilitytonoise inducedhearingloss(NIHL). Atotalof228workerswithNIHLwereselectedas the case group by simple random sampling method,and 230 normal hearing workers with similar age,length and level of noise exposure were selected as the control group.DNA was extracted from peripheral blood of workers of the two groups,and single PMCA2 Results nucleotidepolymorphism (SNP)of wasgenotypedbyMassArraysystem. Theallelefrequenciesofrs1719571 PMCA2 - P and rs14154 of gene in the control population were consistent with Hardy Weinberg equilibrium (both >0.05). There was no significant difference in the distribution of rs1719571 and rs14154 genotypes and allele frequencies between the two P groups(all >0.05).LogisticregressionanalysisshowedthattheriskofNIHLinGAgenotypeofrs1719571waslowerthanthat-P in GG genotype (odds ratio=0.53, 95% confidence interval=0.31 0.90, <0.05), after excluding the effects of age, length of exposure to noise, intensity of exposure to noise, smoking and alcohol consumption. The genotype of SNP rs14154 might not P Conclusion PMCA2 contribute to the genetic susceptibility of NIHL( >0.05). The SNP of rs1719571 is associated with the susceptibilityofNIHL,andGAgenotypemaybeapotentialprotectivefactorforNIHL.

Risk prediction model for high frequency noise-induced hearing loss in young male workers exposed to noise / 中国职业医学

@#Abstract: Objective - - （ ） To investigate the influencing factors of high frequency noise induced hearing loss NIHL in young ， Methods maleworkersexposedtonoise andtoestablishariskpredictionmodelforNIHL. Theyoungmaleswhowerenewly recruitedandwithnormalhearinginnoiseoperationsinanautomobilemanufacturingenterprisefrom 2016to2018wasselected - asresearchsubjectusingaretrospectivecohortstudy.Afollow upsurveywasconducted.MultivariateCoxproportionalhazards， regressionmodelwasusedtoanalyzetheinfluencingfactorsofNIHL andthepartialregressioncoefficientwasusedtoconstruct （PI） PI ， - （PI< ） - theprognosticindex model.Accordingtothe value thesubjectsweredividedintolow riskgroup 0.00 andhigh （PI ） - Results ， risk group ≥0.00 .Kaplan Meiermethod wasused toanalyzetherisk ofNIHL. By 2020 theincidenceofNIHL （ ）， - ， was 33.4% 167/500 which was pure high frequency NIHL and no speech frequency NIHL was detected. Cox proportional - hazard regression model analysis showed that the risk of high frequency NIHL was 2.03 times higher than those with （P< ）， occupational noise exposure level exceeding the standard 0.01 1.62 times higher in those with drinking than in those （P< ）， （P< without drinking 0.05 and 1.69 times higher in those with noisy living environment than in those without drinking ） PI 0.05 . The model constructed according to the partial regression coefficients of the above three influencing factors is PI x x x - （ ， =−0.44+0.71 occupational intensity + 0.49 drinking + 0.52 The probability of high frequency NIHL 3.9% ， ， ， ） - ， ， ， ， 12.3% 19.4% 30.4% 51.1% in the high risk group at 12 24 36 48 and 52 months after taking office was higher than - （ ， ， ， ， ）， that in the low risk group 2.3% 8.3% 10.7% 15.3% and 27.5% especially in the third year after taking office.

Factores asociados a hipoacusia inducida por ruido en trabajadores de una empresa metalmecánica de Talara, Piura periodo 2015 ­ 2018 / Factors associated with hypoacusia induced by noise in workers of a metalmechanical company of Talara, Piura. Period 2015 ­ 2018

Introducción: La hipoacusia es una enfermedad ocupacional frecuente y ocasiona deterioro en la calidad de vida de los trabajadores. Objetivo: Identificar la prevalencia y los factores asociados a hipoacusia inducida por ruido en trabajadores de una empresa metalmecánica. Material y Métodos: Estudio transversal analítico. Se utilizaron datos de historias clínicas ocupacionales para determinar la frecuencia de hipoacusia debido a ruido y sus potenciales factores asociados (edad, sexo, antecedentes personales). Se construyeron modelos de regresión simple y múltiple, estimando razones de prevalencia (RP) utilizando modelos lineales generalizados, familia Poisson y función de enlace log. Resultados: De 1543 trabajadores, la media de edad fue 36,7 años y la mayoría era hombre (93,6%). Solo el 8,2% reportó enfermedad y/o accidente laboral previo a la evaluación ocupacional. El 10,7% presentó hipoacusia debido al ruido. La frecuencia de presentar hipoacusia incrementaba 10% por cada año adicional de edad (RP=1,10, IC95%: 1,09-1,12, p<0,001) y tener el antecedente de enfermedad/accidente laboral incrementaba 75% la frecuencia de presentar hipoacusia (RP=1,75, IC95%: 1,28-2,40, p<0,001). Conclusión: La prevalencia de hipoacusia debido a ruido fue baja, La edad en años y el antecedente de enfermedad/accidente laboral se asociaron de forma positiva a presentar hipoacusia. Se sugiere realizar un seguimiento anual de audiometrías, con especial énfasis en los antecedentes ocupacionales asociados a hipoacusia debido al ruido.

Introduction: Hearing loss is a frequent occupational disease and causes deterioration in the quality of life of workers. The objective was to identify the prevalence and factors associated with noise-induced hearing loss in workers of a metalworking company. Material and Methods: Analytical cross-sectional study. Data from occupational medical records were used to determine the frequency of hearing loss due to noise and its potential associated factors (age, sex, personal history). Simple and multiple regression models were constructed, estimating prevalence ratios (RP) using generalized linear models, Poisson family and log link function. Results: Of 1543 workers, the average age was 36.7 years and the majority were male (93.6%). Only 8.2% reported illness and/or occupational accident prior to the occupational evaluation. 10.7% had hearing loss due to noise. The frequency of presenting hearing loss increased 10% foreach additional year of age (PR = 1.10, 95% CI: 1.09-1.12, p <0.001) and having a history of illness / work accident increased 75% the frequency of presenting hearing loss (RP= 1.75, 95% CI: 1.28-2.40, p <0.001). Conclusion: The prevalence of hearing loss due to noise was low. Age in years and the history of illness / accident were positively associated with hearing loss. It is suggested that annual audiometry follow-up be carried out, with special emphasis on the occupational history associated with hearing loss due to noise.

Analysis of prognostic influencing factors of acute hearing loss after posterior circulation ischemic stroke / 中国医师进修杂志

Objective@#To assess the prognostic influencing factors of acute hearing loss after posterior circulation ischemic stroke.@*Methods@#The clinical data of 50 patients with acute hearing loss caused by posterior circulation ischemic stroke in Dalian Central Hospital Affiliated to Dalian Medical University from January 2016 to December 2018 were retrospectively analyzed. Patients were followed up for 2 to 37 months, with an average of 30 months. At the last follow-up, hearing recovery was assessed. Patients with complete and partial improvement of hearing were classified as hearing improvement group, and patients with no improvement of hearing were classified as hearing without improvement group.@*Results@#There was 32 cases in hearing improvement group and 18 cases in hearing without improvement group. There were no statistical differences in gender composition, age, smoking, diabetes mellitus, hypertension, hyperlipidemia, history of stroke/temporary ischemic attack (TIA), onset to treatment time, hearing loss degree, hearing and vertigo between 2 groups (P>0.05). The proportion of ≥ 2 risk factors in hearing without improvement group was significantly higher than that in hearing improvement group: 17/18 vs. 65.6% (21/32), and there was statistical difference (P<0.05).@*Conclusions@#Acute hearing loss caused by posterior circulation ischemic stroke has a good prognosis, but the patients with multiple risk factors for stroke have poor hearing recovery.

Hipoacusia neurosensorial en niños nacidos con muy bajo peso, atendidos en un hospital pediátrico de alta complejidad / Sensorineural hearing loss in children borned with very low weight, attended at a high complexity pediatric hospital / Perda auditiva em crianças nascidas con muito baixo peso, atendidas em um hospital pediátrico de alta complexidade

INTRODUCCIÓN: El peso al nacer menor a 1.500 gramos es considerado un factor de riesgo auditivo. Analizamos una muestra de 137 niños nacidos con muy bajo peso, atendidos en un hospital pediátrico de alta complejidad. OBJETIVOS: Determinar la frecuencia de hipoacusia neurosensorial; analizar las diferencias entre los subgrupos: screening auditivo neonatal y pacientes de consultorio externo; valorar si existen diferencias entre los subgrupos de peso menor a 1.000 gramos y mayor a 1.000 gramos; investigar el grado de hipoacusia y determinar si la misma es unilateral o bilateral; estimar el porcentaje de niños de screening auditivo que regresaron para seguimiento; describir los factores de riesgo auditivo que presenta la muestra.

INTRODUCTION: Birth weight less than 1,500 grams is considered an auditory risk factor. We analyzed a sample of 137 children born with very low weight and treated in a high complexity pediatric hospital. OBJECTIVE: Determine frequency of sensorineural hearing loss; to analyze differences between the subgroups: neonatal auditory screening and patients from the outpatient clinic; assess if there are differences between subgroups of less and than 1,000 grams; investigate the degree of hearing loss and determine whether it is unilateral or bilateral; estimate the percentage of hearing screening children who returned for follow-up; describe the auditory risk factors presented by the sample.

INTRODUÇÃO: O peso do bebe ao nascer menor do que 1500 gramas é considerado um fator de risco auditivo. Neste trabalho, foi analisada uma amostra de 137 crianças nascidas com muito baixo peso, atendidos em um hospital pediátrico de alta complexidade. Os objetivos do trabalho foram: determinar a frequência de perda auditiva neurossensorial; analisar diferenças entre os subgrupos: screening auditivo neonatal e pacientes de consultório externo; avaliar se existem diferenças entre os subgrupos de peso menor do que 1000 gramas; investigar o grau de perda auditiva e determinar se a mesma foi unilateral ou bilateral; estimar a percentagem de crianças de screening auditivo que regressaram para acompanhamento; descrever os fatores de risco auditivo que apresentou a amostra. MATERIAL E MÉTODO: Foram excluídos pacientes oncológicos, com traumatismo cranioencefálico, transplantados ou com cirurgias do ouvido prévias ao diagnóstico da perda auditiva.

Prática dos Professores da Rede Pública de Ensino em Relação à Avaliação Auditiva em Crianças / Practice of Public School Teachers Regarding Hearing Evaluation in Children

Avaliar se os professores do ensino infantil darede pública de Cabedelo/PB têm conhecimento sobre atriagem auditiva escolar, como realizam esta triagem e se amesma está baseada em achados na literatura. Material eMétodos: Estudo descritivo transversal, realizado por meiode entrevista estruturada com 31 professores do EnsinoPúblico do Município de Cabedelo/ Paraíba - Brasil. Asentrevistas foram transcritas e posteriormente submetidas àanálise. Resultados: A grande maioria dos sujeitosentrevistados tinha conhecimento sobre a triagem auditivaescolar, mas sem haver critérios claros e científicos paraencaminhamento de crianças ao exame auditivo. Conclusão:A triagem auditiva escolar é importante, para detecção deperdas auditivas, mas para ser efetiva, necessita daparticipação consciente e orientada dos professores...

To assess whether the infant school teachersfrom public school in Cabedelo / PB are knowledgeable aboutthe hearing screening at school, how they carry out thisscreening and whether it is based on findings in the literaturecriteria. Material and Methods: This is a cross-sectional study,conducted through structured interviews with 31 teachersof Public Education of the City of Cabedelo / Paraíba. Theinterviews were transcribed and then analyzed. Results:The majority of interviewees have knowledge about hearingscreening at school but without clear and scientific criteria forreferral to the hearing test. Conclusion: The school hearingscreening is important to detect hearing loss, but to beeffective it needs oriented and conscious participation ofteachers...