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1.
Salud(i)cienc., (Impresa) ; 17(3): 247-251, dic. 2009. graf
Article in Spanish | BINACIS | ID: bin-124075

ABSTRACT

Introducción: Evaluamos, en cuanto a recurrencia, los factores pronósticos en el cáncer vesical no infiltrante de músculo y el efecto de la terapia intravesical. Material y métodos: Estudiamos 419 neoplasias vesicales. Realizamos análisis univariados y multivariados sobre 24 variables de estas neoplasias y valoramos distintos tratamientos. Resultados: Existieron diferencias significativas en el tiempo libre hasta la recurrencia, que fue menor en los tumores que recurrieron en menos de 12 meses, en los tumores múltiples (3 o más tumores) y de cúpula; además existieron diferencias estadísticamente significativas cuando se estudiaron dos grupos homogéneos de cirujanos.El empleo de instilaciones vesicales incrementó de forma independiente el tiempo hasta la recidiva. Se demostró que la recurrencia se produjo significativamente más tarde cuando se habían empleado dosis altas de BCG y terapia de mantenimiento. Conclusiones: Los siguientes factores resultaron independientes para explicar menor tiempo libre hasta la recurrencia superficial: recidiva en el primer año, multiplicidad, técnica quirúrgica, no empleo de lavados intravesicales, tratamiento con dosis bajas de BCG y terapia de inducción frente a mantenimiento. El empleo de instilaciones vesicales, con dosis altas de BCG y terapia de mantenimiento, incrementó de forma independiente el tiempo hasta la recidiva.(AU)


Subject(s)
Humans , Male , Female , Urinary Bladder Neoplasms/diagnosis , Urinary Bladder Neoplasms/therapy , Neoplasm Recurrence, Local/diagnosis , Neoplasm Recurrence, Local/prevention & control , Administration, Intravesical , Drug Administration Routes
2.
Salud(i)ciencia (Impresa) ; 17(3): 247-251, dic. 2009. graf
Article in Spanish | LILACS | ID: lil-588840

ABSTRACT

Introducción: Evaluamos, en cuanto a recurrencia, los factores pronósticos en el cáncer vesical no infiltrante de músculo y el efecto de la terapia intravesical. Material y métodos: Estudiamos 419 neoplasias vesicales. Realizamos análisis univariados y multivariados sobre 24 variables de estas neoplasias y valoramos distintos tratamientos. Resultados: Existieron diferencias significativas en el tiempo libre hasta la recurrencia, que fue menor en los tumores que recurrieron en menos de 12 meses, en los tumores múltiples (3 o más tumores) y de cúpula; además existieron diferencias estadísticamente significativas cuando se estudiaron dos grupos homogéneos de cirujanos.El empleo de instilaciones vesicales incrementó de forma independiente el tiempo hasta la recidiva. Se demostró que la recurrencia se produjo significativamente más tarde cuando se habían empleado dosis altas de BCG y terapia de mantenimiento. Conclusiones: Los siguientes factores resultaron independientes para explicar menor tiempo libre hasta la recurrencia superficial: recidiva en el primer año, multiplicidad, técnica quirúrgica, no empleo de lavados intravesicales, tratamiento con dosis bajas de BCG y terapia de inducción frente a mantenimiento. El empleo de instilaciones vesicales, con dosis altas de BCG y terapia de mantenimiento, incrementó de forma independiente el tiempo hasta la recidiva.


Subject(s)
Humans , Male , Female , Administration, Intravesical , Urinary Bladder Neoplasms/diagnosis , Urinary Bladder Neoplasms/therapy , Neoplasm Recurrence, Local/diagnosis , Neoplasm Recurrence, Local/prevention & control , Drug Administration Routes
3.
Arch Esp Urol ; 61(4): 534-7, 2008 May.
Article in Spanish | MEDLINE | ID: mdl-18592775

ABSTRACT

OBJECTIVE: We report one case of ovarian metastasis secondary to a renal clear cell carcinoma. METHODS/RESULTS: 52 year-old consulting for metrorrhagia with the initial diagnosis of primary ovarian carcinoma. Tumor dissemination work up tests reported a renal mass suggestive of ovarian metastasis. Surgery included hysterectomy, double annexectomy, and radical nephrectomy. Final diagnosis was renal clear cell carcinoma with ovarian metastasis. CONCLUSIONS: Metastases to the ovary pose a diagnostic problem in their interpretation, especially when they show a similar histology to the primary ovarian tumor. Due to therapeutic and prognostic implications, it is very important to differentiate if it is a primary ovarian tumor or a metastasis from a renal carcinoma.


Subject(s)
Carcinoma, Renal Cell/secondary , Kidney Neoplasms/pathology , Ovarian Neoplasms/secondary , Female , Humans , Middle Aged
5.
Arch Esp Urol ; 60(2): 125-36, 2007 Mar.
Article in Spanish | MEDLINE | ID: mdl-17484480

ABSTRACT

OBJECTIVES: To evaluate the prognostic significance of the 2002 TNM tumor classification for renal cell carcinoma, as well as other factors intervening in its survival. METHODS: Retrospective chart review of 316 renal carcinomas operated between 1970 and 2003. Twenty-five prognostic variables were analyzed. RESULTS: The histological type was renal cell carcinoma in 90.5% of the patients. Most tumors were T1b or T2, with a Fuhrman nuclear grade I or II. Mean tumor size was 7.17 +/- 3.4 cm. Most cases had a solitary tumor. 8.2% of the patients had lymph node involvement at the time of diagnosis, and 8.6% metastases. The most frequent clinical presentations were hematuria and/or pain. Mean follow-up was 57.8 months. 24.1% of the cases had recurrence, more than 50% of them during the first year. Advanced tumors (T3, T4) had the tendency to have a nuclear grade III-IV, bigger size, necrosis, vascular involvement, lymph node involvement, and metastases. At the end of follow-up, most patients were alive and disease free. The number of months free of disease, the presence of metastatic lymph nodes, the treatment of the first recurrence and the presence of anemia were independent factors for cancer specific mortality. CONCLUSIONS: The modification of the current classification of renal tumors pT3 and pT4 would help to a better decision-making in the therapy of tumors with vascular, perirenal fat or adrenal involvement. Anemia and treatment of the first recurrence are important factors for cancer specific survival.


Subject(s)
Carcinoma, Renal Cell/mortality , Kidney Neoplasms/mortality , Adolescent , Adult , Aged , Aged, 80 and over , Anemia/epidemiology , Anemia/etiology , Carcinoma, Renal Cell/metabolism , Carcinoma, Renal Cell/pathology , Carcinoma, Renal Cell/surgery , Child , Disease-Free Survival , Female , Humans , Kidney Neoplasms/metabolism , Kidney Neoplasms/pathology , Kidney Neoplasms/surgery , Lymph Node Excision , Lymphatic Metastasis , Male , Middle Aged , Neoplasm Staging , Nephrectomy , Prognosis , Retrospective Studies , Spain/epidemiology , Survival Analysis , Tumor Burden
6.
Arch Esp Urol ; 60(1): 31-5, 2007.
Article in Spanish | MEDLINE | ID: mdl-17408169

ABSTRACT

OBJECTIVES: To review the influence of various intravesical treatments on superficial bladder cancer progression. METHODS: We retrospectively reviewed 473 superficial bladder neoplasias. Based on diagnosis and transurethral resection of bladder tumor (TUR BT), and depending on pathology, we proposed different treatment and follow-up schemes, with BCG in 139 cases and intravesical chemotherapy, mainly Mytomicin C, in 80. RESULTS: Overall, the use or not of bladder instillations did not show statistically significant differences in time to progression. The use of intravesical therapy and maintenance therapy was an independent risk factor for disease-free time to progression when compared with induction. CONCLUSIONS: The use of maintenance intravesical therapy with BCG resulted in a delayed progression of superficial bladder cancer, so that it seems the most effective treatment, mainly in moderate-high risk tumors.


Subject(s)
Adjuvants, Immunologic/administration & dosage , Antineoplastic Agents/administration & dosage , BCG Vaccine/administration & dosage , Mitomycin/administration & dosage , Urinary Bladder Neoplasms/drug therapy , Urinary Bladder Neoplasms/pathology , Administration, Intravesical , Disease Progression , Humans , Retrospective Studies
7.
Arch. esp. urol. (Ed. impr.) ; 60(2): 125-136, mar. 2007. ilus, tab
Article in Es | IBECS | ID: ibc-055596

ABSTRACT

Objetivo: Valorar el significado pronóstico de la clasificación tumoral TNM de 2002 para el carcinoma de células renales (CCR), así como otros factores implicados en la supervivencia. Métodos: Estudio retrospectivo de historias clínicas de 316 carcinomas renales intervenidos entre los años 1970 y 2003. Se analizaron 25 variables implicadas en el pronóstico de pacientes con CCR. Resultados: En un 90,5% de pacientes el tipo histológico fue de células renales. La mayoría de los tumores fueron T1b o T2, con un grado nuclear de Fuhrman I o II. La media del tamaño tumoral fue de 7,17 +/- 3,4 cm. En la mayoría de casos existió tumor único. En un 8,2% hubo afectación ganglionar en el momento del diagnóstico y en un 8,6% existían metástasis a distancia. La clínica más frecuente fue hematuria y/o dolor. El seguimiento medio fue de 57,8 meses. Recidivaron un 24,1% de los cuales más del 50% ocurrió en el primer año. Los tumores avanzados (T3, T4) tendieron a presentar un grado nuclear III-IV, mayor tamaño, necrosis, afectación vascular, afectación ganglionar y metástasis a distancia. Al finalizar el seguimiento la mayor parte de pacientes estaba vivo libre de tumor. Los factores que influyeron de forma independiente en la mortalidad cáncer específica fueron los meses libres de enfermedad, la presencia de adenopatías metastásicas, el tratamiento de la primera recidiva y la presencia de anemia. Conclusión: La modificación de la actual clasificación de los tumores renales pT3 y pT4, ayudaría a la mejor toma de decisiones en cuanto a la actitud terapéutica de tumores con afectación vascular, de grasa perirrenal y de glándulas adrenales. La anemia y el tratamiento de la primera recidiva son factores importantes implicados en la supervivencia cáncer específica (AU)


Objectives: To evaluate the prognostic significance of the 2002 TNM tumor classification for renal cell carcinoma, as well as other factors intervening in its survival. Methods: Retrospective chart review of 316 renal carcinomas operated between 1970 and 2003. Twenty- five prognostic variables were analyzed. Results: The histological type was renal cell carcinoma in 90.5% of the patients. Most tumors were T1b or T2, with a Fuhrman nuclear grade I or II. Mean tumor size was 7.17 ± 3.4 cm. Most cases had a solitary tumor. 8.2% of the patients had lymph node involvement at the time of diagnosis, and 8.6% metastases. The most frequent clinical presentations were hematuria and/or pain. Mean follow-up was 57.8 months. 24.1% of the cases had recurrence, more than 50% of them during the first year. Advanced tumors (T3, T4) had the tendency to have a nuclear grade III-IV, bigger size, necrosis, vascular involvement, lymph node involvement, and metastases. At the end of follow-up, most patients were alive and disease free. The number of months free of disease, the presence of metastatic lymph nodes, the treatment of the first recurrence and the presence of anemia were independent factors for cancer specific mortality. Conclusions: The modification of the current classification of renal tumors pT3 and pT4 would help to a better decision-making in the therapy of tumors with vascular, perirenal fat or adrenal involvement. Anemia and treatment of the first recurrence are important factors for cancer specific survival (AU)


Subject(s)
Male , Female , Child , Adolescent , Adult , Middle Aged , Aged , Humans , Carcinoma, Renal Cell/mortality , Kidney Neoplasms/mortality , Anemia/epidemiology , Anemia/etiology , Carcinoma, Renal Cell/metabolism , Carcinoma, Renal Cell/pathology , Carcinoma, Renal Cell/surgery , Lymph Node Excision , Lymphatic Metastasis , Nephrectomy , Prognosis , Retrospective Studies , Spain/epidemiology , Survival Analysis , Disease-Free Survival , Neoplasm Staging , Kidney Neoplasms/metabolism , Kidney Neoplasms/pathology , Kidney Neoplasms/surgery , Neoplasms/pathology
8.
Arch. esp. urol. (Ed. impr.) ; 60(1): 31-35, ene.-feb. 2007. ilus, tab
Article in Es | IBECS | ID: ibc-054450

ABSTRACT

OBJETIVOS: Revisar la influencia de distintos tratamientos endovesicales sobre la progresión del cáncer vesical superficial. METODOS: Se revisaron retrospectivamente un total de 473 neoplasias vesicales superficiales. A partir del diagnóstico y la RTU vesical, y en función del resultado anatomopatológico, se plantearon distintos esquemas de seguimiento y tratamiento complementario, se empleó BCG en 139 casos y quimioterapia endovesical en 80 pacientes fundamentalmente Mitomicina C (MMC). RESULTADOS: Globalmente, el empleo o no de instilaciones vesicales no mostró diferencias estadísticamente significativas en cuanto al tiempo de progresión Resultó factor independiente para explicar un menor tiempo libre hasta la progresión el empleo de terapia endovesical con terapia de mantenimiento frente a inducción. CONCLUSIONES: La utilización de terapia endovesical de mantenimiento con BCG implicó una progresión más tardía del cáncer vesical superficial, por lo que parece el tratamiento más eficaz, sobretodo en tumores de moderado y alto riesgo (AU)


OBJECTIVES: To review the influence of various intravesical treatments on superficial bladder cancer progression. METHODS: We retrospectively reviewed 473 superficial bladder neoplasias. Based on diagnosis and transurethral resection of bladder tumor (TUR BT), and depending on pathology, we proposed different treatment and follow-up schemes, with BCG in 139 cases and intravesical chemotherapy, mainly Mytomicin C, in 80. RESULTS: Overall, the use or not of bladder instillations did not show statistically significant differences in time to progression. The use of intravesical therapy and maintenance therapy was an independent risk factor for disease-free time to progression when compared with induction. CONCLUSIONS: The use of maintenance intravesical therapy with BCG resulted in a delayed progression of superficial bladder cancer, so that it seems the most effective treatment, mainly in moderate-high risk tumors


Subject(s)
Humans , Adjuvants, Immunologic/administration & dosage , Antineoplastic Agents/administration & dosage , BCG Vaccine/administration & dosage , Mitomycin/administration & dosage , Urinary Bladder Neoplasms/drug therapy , Urinary Bladder Neoplasms/pathology , Administration, Intravesical , Disease Progression , Retrospective Studies
10.
Arch Esp Urol ; 59(2): 189-92, 2006 Mar.
Article in Spanish | MEDLINE | ID: mdl-16649527

ABSTRACT

OBJECTIVES: Syphilis is a systemic disease the course of which follows successive clinical stages. Central nervous system and spinal cord involvement on late phases may lead to bladder dysfunction. We report one case of neurosyphilis with associated bladder hyperreflexia. METHODS/RESULTS: 51-year-old male with the diagnosis of neurosyphilis consulting for voiding disorders with evidence of detrusor hyperactivity of neurogenic etiology on the urodynamic study. CONCLUSIONS: The differential diagnosis of neurogenic bladder in patients with psychiatric or neurological symptoms should include neurosyphilis. Etiologic diagnosis is obtained by cerebrospinal fluid examination, and the diagnosis of bladder dysfunction by urodynamic study.


Subject(s)
Neurosyphilis/complications , Urinary Bladder, Neurogenic/etiology , Humans , Male , Middle Aged
11.
Arch Esp Urol ; 59(2): 195-8, 2006 Mar.
Article in Spanish | MEDLINE | ID: mdl-16649529

ABSTRACT

OBJECTIVES: To report a rare clinical case of solitary pararenal fibrous tumor, analyzing its pathological characteristics and prognosis by a bibliographic review. METHODS/RESULTS: We present the case of a 36-year-old male consulting for right flank colic pain, which was diagnosed of a solid mass in the lower pole of the right kidney and underwent right radical nephrectomy. Pathological study of the surgical specimen showed the presence of a solitary pararenal fibrous tumor. CONCLUSIONS: Solitary fibrous tumor is a rare neoplasia, being its pararenal localization even rarer. It is a tumor with benign behavior in up to 90% of the cases. The immunohistochemical study is the key to diagnosis.


Subject(s)
Kidney Neoplasms , Neoplasms, Fibrous Tissue , Adult , Humans , Kidney Neoplasms/diagnostic imaging , Kidney Neoplasms/surgery , Male , Neoplasms, Fibrous Tissue/diagnostic imaging , Neoplasms, Fibrous Tissue/surgery , Radiography
12.
Arch Esp Urol ; 59(3): 297-9, 2006 Apr.
Article in Spanish | MEDLINE | ID: mdl-16724718

ABSTRACT

OBJECTIVE: To report a rare case of a giant epidermoid cyst in an intertesticular localization, analyzing its histological and pathologic features, and to perform a bibliographic review. METHODS/RESULTS: We report the case of a 49-year-old male consulting for a slowly growing intra-scrotal mass of five years of evolution causing discomfort because of its size. After excision the pathology report showed the presence of a keratoid epidermoid cyst very big in size. CONCLUSIONS: Superficial scrotal epidermoid cysts are frequent in clinical practice; that is not the case of the so-called "intra scrotal inclusion cysts". Epidermoid cysts are firm, mobile, slowly growing, generally asymptomatic intra epidermal neoformations. There are descriptions in multiple sites, even the genitalia, nevertheless their size in this location does not usually pass 5 cm.


Subject(s)
Epidermal Cyst/pathology , Testicular Diseases/pathology , Humans , Male , Middle Aged
13.
Arch. esp. urol. (Ed. impr.) ; 59(3): 297-299, abr. 2006. ilus
Article in Es | IBECS | ID: ibc-046832

ABSTRACT

OBJETIVO: Añadir a la literatura un caso clínico poco frecuente de quiste epidermoide gigante de localización intertesticular, analizando las características histológicas y patológicas del mismo y realizando una revisión de la literatura al respecto. MÉTODOS/RESULTADOS: Presentamos el caso de un varón de 49 años que consultó por bultoma intraescrotal de 5 años de evolución y lento crecimiento que le ocasionaba molestias por su gran tamaño. Tras exéresis del mismo, el resultado anatomopatológico de la muestra evidenció la presencia de un quiste epidermoide queratinoso de gran tamaño. CONCLUSIONES: Los quistes epidérmicos escrotales superficiales son de frecuente aparición en la práctica clínica, no así los denominados “de inclusión” intraescrotales. Los Quistes Epidermoides son neoformaciones intraepidérmicas, firmes y móviles de crecimiento lento y habitualmente asintomáticos. Están descritos en múltiples localizaciones, incluso en genitales, sin embargo el tamaño de estos a este nivel no suele superar los 5 cm


OBJECTIVE: To report a rare case of a giant epidermoid cyst in an intertesticular localization, analyzing its histological and pathologic features, and to perform a bibliographic review. METHODS/RESULTS: We report the case of a 49-year-old male consulting for a slowly growing intra-scrotal mass of five years of evolution causing discomfort because of its size. After excision the pathology report showed the presence of a keratoid epidermoid cyst very big in size. CONCLUSIONS: Superficial scrotal epidermoid cysts are frequent in clinical practice; that is not the case of the so-called “intra scrotal inclusion cysts”. Epidermoid cysts are firm, mobile, slowly growing, generally asymptomatic intra epidermal neoformations. There are descriptions in multiple sites, even the genitalia, nevertheless their size in this location does not usually pass 5 cm


Subject(s)
Male , Middle Aged , Humans , Epidermal Cyst/pathology , Testicular Diseases/pathology
15.
Arch. esp. urol. (Ed. impr.) ; 59(2): 186-189, mar. 2006. ilus
Article in Es | IBECS | ID: ibc-046798

ABSTRACT

OBJETIVO: Añadir a la literatura un caso clínicopoco frecuente de tumor fibroso solitario pararrenal, analizando las características anatomo-patológicas del mismo así como su pronóstico mediante una revisión bibliográficade la literatura al respecto.MÉTODOS/RESULTADOS: Presentamos el caso clínico de un varón de 36 años que consultó por dolor cólico en fosa renal derecha, siendo diagnosticado de masa sólida en polo inferior riñon derecho, motivo por el que fue sometido a una nefrectomía radical derecha. El estudio histológico de la pieza evidenció la presencia de un tumor fibroso solitario pararrenal.CONCLUSIONES: El tumor fibroso solitario es una neoplasiamuy poco frecuente siendo su localización pararrenal aún menos frecuente, siendo una tumoración de comportamientobenigno en hasta un 90 % de casos. En su diagnósticoresulta clave el estudio inmunohistoquímico


OBJECTIVES: To report a rare clinical case of solitary pararenal fibrous tumor, analyzing its pathological characteristics and prognosis by a bibliographic review. METHODS/RESULTS: We present the case of a 36-year-old male consulting for right flank colic pain, which was diagnosed of a solid mass in the lower pole of the right kidney and underwent right radical nephrectomy. Pathological study of the surgical specimen showed the presence of a solitary pararenal fibrous tumor. CONCLUSIONS: Solitary fibrous tumor is a rare neoplasia, being its pararenal localization even rarer. It is a tumor with benign behavior in up to 90% of the cases. The immunohistochemical study is the key to diagnosis


Subject(s)
Male , Adult , Humans , Neoplasms, Fibrous Tissue/pathology , Neoplasms, Fibrous Tissue/surgery , Testicular Neoplasms/pathology , Testicular Neoplasms/surgery
16.
Arch. esp. urol. (Ed. impr.) ; 59(2): 189-192, mar. 2006. ilus
Article in Es | IBECS | ID: ibc-046799

ABSTRACT

OBJETIVO: La sífilis es una enfermedad sistémicaque cursa en estadios clínicos sucesivos. La afectacióndel sistema nervioso central y de la médula espinal en fases tardías puede provocar disfunción vesical. Presentamosun caso de neurosífilis con hiperreflexia asociada.MÉTODO: Varón de 51 años diagnosticado de neurosífilisque consultó por trastornos miccionales objetivando en el estudio urodinámico un detrusor hiperactivo de causa neurogénica.CONCLUSIONES: En el diagnóstico diferencial de vejiga neurógena en pacientes que presentan síntomas psiquiátricosy neurológicos debería ser considerada la neurosífilis.El diagnóstico etiológico es por examen del líquido cefalorraquídeo y el diagnóstico de su disfunción vesical mediante estudio urodinámico


OBJECTIVES: Syphilis is a systemic disease the course of which follows successive clinical stages. Central nervous system and spinal cord involvement on late phases may lead to bladder dysfunction. We report one case of neurosyphilis with associated bladder hyperreflexia. ;;METHODS/RESULTS: 51-year-old male with the diagnosis of neurosyphilis consulting for voiding disorders with ;;evidence of detrusor hyperactivity of neurogenic etiology on the urodynamic study. ;;CONCLUSIONS: The differential diagnosis of neurogenic ;;bladder in patients with psychiatric or neurological symptoms should include neurosyphilis. Etiologic diagnosis is obtained by cerebrospinal fluid examination, and the diagnosis of bladder dysfunction by urodynamic study


Subject(s)
Male , Middle Aged , Humans , Neurosyphilis/complications , Urinary Bladder, Neurogenic/etiology
17.
Arch. esp. urol. (Ed. impr.) ; 59(2): 195-198, mar. 2006. ilus
Article in Es | IBECS | ID: ibc-046801

ABSTRACT

OBJETIVO: Añadir a la literatura un caso clínicopoco frecuente de tumor fibroso solitario pararrenal, analizando las características anatomo-patológicas del mismo así como su pronóstico mediante una revisión bibliográficade la literatura al respecto.MÉTODOS/RESULTADOS: Presentamos el caso clínico de un varón de 36 años que consultó por dolor cólico en fosa renal derecha, siendo diagnosticado de masa sólida en polo inferior riñon derecho, motivo por el que fue sometido a una nefrectomía radical derecha. El estudio histológico de la pieza evidenció la presencia de un tumor fibroso solitario pararrenal.CONCLUSIONES: El tumor fibroso solitario es una neoplasiamuy poco frecuente siendo su localización pararrenal aún menos frecuente, siendo una tumoración de comportamientobenigno en hasta un 90 % de casos. En su diagnósticoresulta clave el estudio inmunohistoquímico


OBJECTIVES: To report a rare clinical case of solitary pararenal fibrous tumor, analyzing its pathological characteristics and prognosis by a bibliographic review.METHODS/RESULTS: We present the case of a 36-year-old male consulting for right flank colic pain, which was diagnosed of a solid mass in the lower pole of the right kidney and underwent right radical nephrectomy. Pathologicalstudy of the surgical specimen showed the presence of a solitary pararenal fibrous tumor.CONCLUSIONS: Solitary fibrous tumor is a rare neoplasia,being its pararenal localization even rarer. It is a tumor with benign behavior in up to 90% of the cases. The immunohistochemicalstudy is the key to diagnosis


Subject(s)
Male , Adult , Humans , Kidney Neoplasms , Kidney Neoplasms/surgery , Neoplasms, Fibrous Tissue , Neoplasms, Fibrous Tissue/surgery
18.
Arch Esp Urol ; 58(3): 227-31, 2005 Apr.
Article in Spanish | MEDLINE | ID: mdl-15906616

ABSTRACT

OBJECTIVES: To determine the efficacy of endoscopical injections for the treatment of stress urinary incontinence (SUI), evaluating its low invasiveness and positive impact on quality of life. METHODS/RESULTS: Belween 1997--2003 30 procedures of periurethral injection of various substances for urinary incontinence were performed at our department in women between 47-80 years. All patients were evaluated before surgery, clinically and urodynamically, in accordance to international standardized parameters (filling pressure/flow studies, maximum urethral closure pressure, LPP-leak point pressure). The kind of material employed for injection, surgical technique and satisfaction degree were also evaluated. RESULTS: The indication for surgery was SUI in 17 cases (56.6%), and mixed urinary incontinence in 73 cases (43.3%). 16 cases (53.3%) had history of previous surgery for SUI. Regarding urodynamic parameters, 19 patients (63.3%) have a maximum urethral closure pressure below 25 H2O cm, and 22 patients (73.3%) had a leak point pressure below 60 H2O cm. Collagen was employed in six cases (20%) and macroplastic in 24 (80%) (14 of them with the MIS system). 22 patients had three injection sites (73.3%). Mean follow-up was 38 months. Continence outcomes were evaluated in relation to complete continence (12 cases, 40%), mild incontinence and patient satisfaction (11 cases, 36.6%), and severe incontinence (7 cases, 23.3%). CONCLUSIONS: 1-To achieve acceptable results it is mandatory to do the best possible indication (Mc Guire type III SUI). 2.-There is an excellent relationship between minimal invasiveness and good results.


Subject(s)
Urinary Incontinence/therapy , Aged , Aged, 80 and over , Biocompatible Materials/administration & dosage , Female , Humans , Injections , Middle Aged
19.
Arch. esp. urol. (Ed. impr.) ; 58(3): 227-231, abr. 2005. ilus, tab
Article in Es | IBECS | ID: ibc-039233

ABSTRACT

OBJETIVO: Determinar la efectividad delas inyecciones endoscópicas en la corrección de laIUE, valorando su escasa agresividad y su impactopositivo en la calidad de vida.MÉTODOS/RESULTADOS: Entre 1997-2003 se realizaronen nuestro servicio 30 intervenciones por incontinenciaurinaria con inyección periuretral de diversassustancias, en mujeres con edades comprendidas entre47-80 años. Todas las pacientes fueron valoradas previaintervención clínica y urodinámicamente atendiendoa los parámetros internacionalmente reconocidos (cistomanometríade llenado, presión uretral máxima, LPP(Leak point presure o presión abdominal de escape).También se valoró el tipo de material utilizado para lainyección, técnica quirúrgica y grado de satisfacción.RESULTADOS: En 17 casos (56.6%) la indicación quirúrgicafue por IUE pura mientras que en 13 casos(43.3%) fue mixta. En 16 casos (53.3%) existían anteÓscarRodríguez FabaC/ Amsterdam, 4 - 7ºA33011 Oviedo.Asturias. (España)e-mail: oscar.rodriguez@sespa.princast.esTrabajo recibido: 8 de junio 2004CorrespondenciaPalabras clave: Sustancias periuretrales.Incontinencia tipo III.Summary.- OBJECTIVES: To determine the efficacyof endoscopical injections for the treatment of stressurinary incontinence (SUI), evaluating its low invasivenessand positive impact on quality of life.METHODS/RESULTS: Between 1997-2003 30 proceduresof periurethral injection of various substances for urinaryincontinence were performed at our department inwomen between 47-80 years. All patients wereevaluated before surgery, clinically and urodynamically,cedentes de intervenciones previas por IUE. En cuantoa parámetros urodinámicos en 19 pacientes( 63.3%) lapresión máxima de cierre uretral fue menor de 25 cmde agua y en 22 pacientes ( 73.3%) , el leak point presurefue menor de 60 cm de agua. En 6 pacientes(20%) se utilizó colageno y en 24 pacientes (80%)macroplastique ( 14 de ellos con sistema M.I.S). En 22casos (73.3%) se realizaron 3 habones. El tiempomedio de seguimiento fue de 38 meses. El resultado encuanto a continencia se valoró en relación a que lapaciente estuviese totalmente seca ( 12 casos 40%),incontinencia leve pero satisfecha (11 casos 36.6%) eincontinencia grave ( 7 casos, 23.3%).CONCLUSIONES: 1.-Resulta imprescindible para obtenerresultados aceptables la mejor de las posibles indicaciones( IUE tipo III de Mc Guire). 2.- Existe una relaciónexcelente entre la mínima agresividad y los buenosresultados


OBJECTIVES: To determine the efficacyof endoscopical injections for the treatment of stressurinary incontinence (SUI), evaluating its low invasivenessand positive impact on quality of life.METHODS/RESULTS: Between 1997-2003 30 proceduresof periurethral injection of various substances for urinaryincontinence were performed at our department inwomen between 47-80 years. All patients wereevaluated before surgery, clinically and urodynamically,in accordance to international standardized parameters(filling pressure/flow studies, maximum urethral closurepressure, LPP-leak point pressure). The kind of materialemployed for injection, surgical technique and satisfactiondegree were also evaluated.RESULTS: The indication for surgery was SUI in 17cases (56.6%), and mixed urinary incontinence in 13cases (43.3%). 16 cases (53.3%) had history ofprevious surgery for SUI. Regarding urodynamicparameters,19 patients (63.3%) have a maximum urethralclosure pressure below 25 H2O cm, and 22 patients(73.3%) had a leak point pressure below 60 H2O cm.Collagen was employed in six cases (20%) andmacroplastic in 24 (80%) (14 of them with the MISsystem). 22 patients had three injection sites (73.3%).Mean follow-up was 38 months. Continence outcomeswere evaluated in relation to complete continence (12cases, 40%), mild incontinence and patient satisfaction(11 cases, 36.6%), and severe incontinence (7 cases,23.3%).CONCLUSIONS: 1-To achieve acceptable results it ismandatory to do the best possible indication (Mc Guiretype III SUI). 2.-There is an excellent relationship betweenminimal invasiveness and good results


Subject(s)
Female , Aged , Humans , Urinary Incontinence/therapy , Biocompatible Materials/administration & dosage , Injections
20.
Arch Esp Urol ; 57(6): 646-9, 2004.
Article in Spanish | MEDLINE | ID: mdl-15382442

ABSTRACT

OBJECTIVES: To report a new case of well-differentiated renal liposarcoma, and to describe its clinical features, diagnosis, treatment, and differences with other mesenchymal tumors of the retroperitoneum. METHODS: We perform a clinical review of renal mesenchymal tumors, especially liposarcomas. We report one case of well-differentiated renal liposarcoma in a 52-year-old female, and review current lines of treatment and follow-up. RESULTS/CONCLUSIONS: The well-differentiated renal liposarcoma is a very unfrequent mesenchymal tumor, for which it is necessary to know exactly its origin in the renal parenchyma. The treatment of choice is complete tumor exeresis; close follow-up should be exercised because even though it does not metastasize, local recurrences appear in 30% of the cases.


Subject(s)
Kidney Neoplasms/pathology , Kidney/pathology , Liposarcoma/pathology , Female , Humans , Kidney/diagnostic imaging , Kidney/surgery , Kidney Neoplasms/diagnostic imaging , Kidney Neoplasms/surgery , Liposarcoma/diagnostic imaging , Liposarcoma/surgery , Middle Aged , Tomography, X-Ray Computed , Treatment Outcome , Urologic Surgical Procedures/methods
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