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We applied natural language processing (NLP) to a corpus extracted from 4 hours of expert panel discussion transcripts to determine the sustainability of a Stage II-III clinical trial of online social support interventions for Hispanic and African American dementia caregivers. Prominent topics included Technology/hard to reach populations, Training younger populations, Building trust, Privacy and security issues, Simplification of screening questions and recruitment procedures, Understanding participants' needs, Planning strategies and logistics, Potential recruitment places, Adjusting intervention size downwards to engage elderly participants, Targeting different generations, Internet-based interventions by age range, and Providing step-by-step instructions and an overview of the entire research process during recruitment. The application of NLP to qualitative data on a dementia caregiving clinical trial provides useful insights for recruitment, retention, and adherence to guidelines for such interventions serving Hispanic and African American dementia caregivers.
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Negro o Afroamericano , Cuidadores , Demencia , Hispánicos o Latinos , Procesamiento de Lenguaje Natural , Selección de Paciente , Apoyo Social , Humanos , Internet , AncianoRESUMEN
We applied social network analysis to compare Hispanic and Black dementia caregiving networks on Twitter that were established as part of a clinical trial from January 12, 2022, to October 31, 2022. We extracted Twitter data from our caregiver support communities (N=1980 followers, 811 enrollees) via the Twitter API and used social network analysis software to compare friend/follower interactions within each Hispanic and Black caregiving network. Analysis of the social networks revealed that enrolled family caregivers without prior social media competency had overall low connectedness compared to both enrolled and non-enrolled caregivers with social media competency, who were more integrated into the communities that developed through the clinical trial, partly due to their ties to external dementia caregiving groups. These observed dynamics will help to guide further social media-based interventions and also support the observation that our recruitment strategies effectively enrolled family caregivers with various levels of social media competency.
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Cuidadores , Demencia , Redes Sociales en Línea , Medios de Comunicación Sociales , Apoyo Social , Humanos , Negro o Afroamericano , Cuidadores/psicología , Demencia/etnología , Demencia/psicología , Demencia/terapia , Hispánicos o Latinos , Red SocialRESUMEN
We compared emotional valence scores as determined via machine learning approaches to human-coded scores of direct messages on Twitter from our 2,301 followers during a Twitter-based clinical trial screening for Hispanic and African American family caregivers of persons with dementia. We manually assigned emotional valence scores to 249 randomly selected direct Twitter messages from our followers (N=2,301), then we applied three machine learning sentiment analysis algorithms to extract emotional valence scores for each message and compared their mean scores to the human coding results. The aggregated mean emotional scores from the natural language processing were slightly positive, while the mean score from human coding as a gold standard was negative. Clusters of strongly negative sentiments were observed in followers' responses to being found non-eligible for the study, indicating a significant need for alternative strategies to provide similar research opportunities to non-eligible family caregivers.
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Demencia , Emociones , Medios de Comunicación Sociales , Humanos , Algoritmos , Negro o Afroamericano , Cuidadores , Demencia/diagnóstico , Hispánicos o Latinos , Aprendizaje AutomáticoRESUMEN
We applied natural language processing and topic modeling to publicly available abstracts and titles of 263 papers in the scientific literature mentioning AI and demographics (corpus 1 before Covid-19, corpus 2 after Covid-19) extracted from the MEDLINE database. We found exponential growth of AI studies mentioning demographics since the pandemic (Before Covid-19: N= 40 vs. After Covid-19: N= 223) [forecast model equation: ln(Number of Records) = 250.543*ln(Year) + -1904.38, p = 0.0005229]. Topics related to diagnostic imaging, quality of life, Covid, psychology, and smartphone increased during the pandemic, while cancer-related topics decreased. The application of topic modeling to the scientific literature on AI and demographics provides a foundation for the next steps regarding developing guidelines for the ethical use of AI for African American dementia caregivers.
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Inteligencia Artificial , Atención a la Salud , Demencia , Humanos , Negro o Afroamericano , Demencia/terapia , Calidad de Vida , Atención a la Salud/éticaRESUMEN
Accurate in-hospital mortality prediction can reflect the prognosis of patients, help guide allocation of clinical resources, and help clinicians make the right care decisions. There are limitations to using traditional logistic regression models when assessing the model performance of comorbidity measures to predict in-hospital mortality. Meanwhile, the use of novel machine-learning methods is growing rapidly. In 2021, the Agency for Healthcare Research and Quality published new guidelines for using the Present-on-Admission (POA) indicator from the International Classification of Diseases, Tenth Revision, for coding comorbidities to predict in-hospital mortality from the Elixhauser's comorbidity measurement method. We compared the model performance of logistic regression, elastic net model, and artificial neural network (ANN) to predict in-hospital mortality from Elixhauser's measures under the updated POA guidelines. In this retrospective analysis, 1,810,106 adult Medicare inpatient admissions from six US states admitted after September 23, 2017, and discharged before April 11, 2019 were extracted from the Centers for Medicare and Medicaid Services data warehouse. The POA indicator was used to distinguish pre-existing comorbidities from complications that occurred during hospitalization. All models performed well (C-statistics >0.77). Elastic net method generated a parsimonious model, in which there were five fewer comorbidities selected to predict in-hospital mortality with similar predictive power compared to the logistic regression model. ANN had the highest C-statistics compared to the other two models (0.800 vs. 0.791 and 0.791). Elastic net model and AAN can be applied successfully to predict in-hospital mortality.
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Hospitalización , Medicare , Anciano , Adulto , Humanos , Estados Unidos , Mortalidad Hospitalaria , Estudios Retrospectivos , Comorbilidad , Aprendizaje AutomáticoRESUMEN
We randomly examined Korean-language Tweets mentioning dementia/Alzheimer's disease (n= 12,413) posted from November 28 to December 9, 2020, without limiting geographical locations. We independently applied Latent Dirichlet Allocation (LDA) topic modeling and qualitative content analysis to the texts of the Tweets. We compared the themes extracted by LDA topic modeling to those identified via manual coding methods. A total of 16 themes were detected from manual coding, with inter-rater reliability (Cohen's kappa) of 0.842. The proportions of the most prominent themes were: burdens of family caregiving (48.50%), reports of wandering/missing family members with dementia (18.12%), stigma (13.64%), prevention strategies (5.07%), risk factors (4.91%), healthcare policy (3.26%), and elder abuse/safety issues (1.75%). Seven themes whose contents were similar to themes derived from manual coding were extracted from the LDA topic modeling results (perplexity: -6.39, coherence score: 0.45). Our findings suggest that applying LDA topic modeling can be fairly effective at extracting themes from Korean Twitter discussions, in a manner analogous to qualitative coding, to gain insights regarding caregiving for family members with dementia, and our approach can be applied to other languages.
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Demencia , Medios de Comunicación Sociales , Anciano , Humanos , Lenguaje , Reproducibilidad de los Resultados , República de CoreaRESUMEN
We randomly extracted Korean-language Tweets mentioning dementia/Alzheimer's disease (n= 12,413) from November 28 to December 9, 2020. We independently applied three machine learning algorithms (Afinn, Syuzhet, and Bing) using natural language processing (NLP) techniques and qualitative manual scoring to assign emotional valence scores to Tweets. We then compared the means and distributions of the four emotional valence scores. Visual examination of the graphs produced indicated that each method exhibited unique patterns. The aggregated mean emotional valence scores from the NLP methods were mostly neutral, vs. slightly negative for manual coding (Afinn 0.029, 95% CI [-0.019, 0.077]; Syuzhet 0.266, [0.236, 0.295]; Bing -0.271, [-0.289, -0.252]; manual coding -1.601, [-1.632, -1.569]). One-way analysis of variance (ANOVA) showed no statistically significant differences among the four means after normalization. These findings suggest that the application of NLP can be fairly effective in extracting emotional valence scores from Korean-language Twitter content to gain insights regarding family caregiving for a person with dementia.
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Demencia , Medios de Comunicación Sociales , Algoritmos , Cuidadores , Humanos , Aprendizaje AutomáticoRESUMEN
We applied mixed-methods to refine our first version of the Twitter message library (English 400, translated into Spanish 400) for African Americans and Hispanic family caregivers for a person with dementia. We conducted a series of expert panels to collect quantitative and qualitative data using surveys and in-depth interviews. Using mixed methods to ensure unbiased results, the panelists first independently scored them (1 message/5 panelist) on a scale of 1 to 4 (1: lowest, 4: highest), followed by in-depth interviews and group discussions. Survey results showed that the average score was 3.47, indicating good to excellent (SD 0.35, ranges from 1.8 to 4). Quantitative surveys and qualitative interviews showed different results in emotional support messages.
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Demencia , Medios de Comunicación Sociales , Negro o Afroamericano/psicología , Cuidadores/psicología , Demencia/psicología , Hispánicos o Latinos , Humanos , Apoyo SocialRESUMEN
We applied machine learning algorithms to examine the relationship between demographics and outcomes of the social work services used by Hispanic family caregivers of persons with dementia recruited for a clinical trial in New York City. The social work service needs were largely concentrated on instrumental support to gain access to the healthcare system rather than other concrete services (e.g., housing or food programs) or to address psychological needs among the caregivers with relatively higher income. A finding from the machine learning approach was that among those who receive medical-related social work services, frequent users (≥10 times) with high family friend support(>4) were more likely than frequent users without such support to have their issues resolved (Accuracy: 81.9%, AUC: 0.82, F-measure: 0.86 by J48). Even though half of the participants received social work services multiple times, the needs of the caregivers remained unmet unless they sought social work services frequently (more than ten times).
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Cuidadores , Demencia , Cuidadores/psicología , Demencia/psicología , Necesidades y Demandas de Servicios de Salud , Hispánicos o Latinos , Humanos , Aprendizaje Automático , Apoyo Social , Servicio SocialRESUMEN
OBJECTIVE: We designed an mHealth application (app) user interface (UI) prototype informed by participatory design sessions, persuasive systems design (PSD) principles, and Lorig and Holman's self-management behavior framework to support self-management activities of Hispanic informal dementia caregivers and assessed their perceptions and preferences regarding features and functions of the app. MATERIALS AND METHODS: Our observational usability study design employed qualitative methods and forced choice preference assessments to identify: (1) the relationship between user preferences for UI features and functions and PSD principles and (2) user preferences for UI design features and functions and app functionality. We evaluated 16 pairs of mHealth app UI prototype designs. Eight paper-based paired designs were used to assess the relationship between PSD principles and caregiver preferences for UI features and functions to support self-management. An Apple iPad WIFI 32GB was used to display another 8 paired designs and assess caregiver preferences for UI functions to support the self-management process. RESULTS: Caregivers preferred an app UI with features and functions that incorporated a greater number of PSD principles and included an infographic to facilitate self-management. Moreover, caregivers preferred a design that did not depend on manual data entry, opting instead for functions such as drop-down list, drag-and-drop, and voice query to prioritize, choose, decide, and search when performing self-management activities. CONCLUSION: Our assessment approaches allowed us to discern which UI features, functions, and designs caregivers preferred. The targeted application of PSD principles in UI designs holds promise for supporting personalized problem identification, goal setting, decision-making, and action planning as strategies for improving caregiver self-management confidence.
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We extracted 3,291,101 Tweets using hashtags associated with African American-related discourse (#BlackTwitter, #BlackLivesMatter, #StayWoke) and 1,382,441 Tweets from a control set (general or no hashtags) from September 1, 2019 to December 31, 2019 using the Twitter API. We also extracted a literary historical corpus of 14,692 poems and prose writings by African American authors and 66,083 items authored by others as a control, including poems, plays, short stories, novels and essays, using a cloud-based machine learning platform (Amazon SageMaker) via ProQuest TDM Studio. Lastly, we combined statistics from log likelihood and Fisher's exact tests as well as feature analysis of a batch-trained Naive Bayes classifier to select lexicons of terms most strongly associated with the target or control texts. The resulting Tweet-derived African American lexicon contains 1,734 unigrams, while the control contains 2,266 unigrams. This initial version of a lexicon-based African American Tweet detection algorithm developed using Tweet texts will be useful to inform culturally sensitive Twitter-based social support interventions for African American dementia caregivers.
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Demencia , Medios de Comunicación Sociales , Negro o Afroamericano , Algoritmos , Inteligencia Artificial , Teorema de Bayes , Cuidadores , Humanos , Apoyo SocialRESUMEN
We interviewed six clinicians to learn about their lived experience using electronic health records (EHR, Allscripts users) using a semi-structured interview guide in an academic medical center in New York City from October to November 2016. Each participant interview lasted approximately one to two hours. We applied a clustering algorithm to the interview transcript to detect topics, applying natural language processing (NLP). We visualized eight themes using network diagrams (Louvain modularity 0.70). Novel findings include the need for a concise and organized display and data entry page, the user controlling functions for orders, medications, radiology reports, and missing signals of indentation or filtering functions in the order page and lab results. Application of topic modeling to qualitative interview data provides far-reaching research insights into the clinicians' lived experience of EHR and future optimal EHR design to address human-computer interaction issues in an acute care setting.
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Registros Electrónicos de Salud , Procesamiento de Lenguaje Natural , Centros Médicos Académicos , Algoritmos , Humanos , Ciudad de Nueva YorkRESUMEN
We randomly extracted Tweets mentioning dementia/Alzheimer's caregiving-related terms (n= 58,094) from Aug 23, 2019, to Sep 14, 2020, via an API. We applied a clustering algorithm and natural language processing (NLP) to publicly available English Tweets to detect topics and sentiment. We compared emotional valence scores of Tweets from before (through the end of 2019) and after the beginning of the COVID-19 pandemic (2020-). Prevalence of topics related to caregiver emotional distress (e.g., depression, helplessness, stigma, loneliness, elder abuse) and caregiver coping (e.g., resilience, love, reading books) increased, and topics related to late-stage dementia caregiving (e.g., nursing home placement, hospice, palliative care) decreased during the pandemic. The mean emotional valence score significantly decreased from 1.18 (SD 1.57; range -7.1 to 7.9) to 0.86 (SD 1.57; range -5.5 to 6.85) after the advent of COVID-19 (difference -0.32 CI: -0.35, -0.29). The application of topic modeling and sentiment analysis to streaming social media provides a foundation for research insights regarding mental health needs for family caregivers of a person with ADRD during COVID-19 pandemic.
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Enfermedad de Alzheimer , COVID-19 , Medios de Comunicación Sociales , Anciano , Enfermedad de Alzheimer/epidemiología , Actitud , Cuidadores , Humanos , Pandemias , Prevalencia , SARS-CoV-2 , Análisis de SentimientosRESUMEN
We applied social network analysis (SNA) on Tweets to compare Hispanic and Black dementia caregiving networks. We randomly extracted Tweets mentioning dementia caregiving and related terms from corpora collected daily via the Twitter API from September 1 to December 31, 2019 (initial corpus: n = 2,742,539 Tweets, random sample n = 549,380 English Tweets, n= 185,684 Spanish Tweets). After removing bot-generated Tweets, we first applied a lexicon-based demographic inference algorithm to automatically identify Tweets likely authored by Black and Hispanic individuals using Python (n = 114,511 English, n = 1,185 Spanish). Then, using ORA, we computed network measures at macro, meso, and micro levels and applied the Louvain clustering algorithm to detect groups within each Hispanic and Black caregiving network. Both networks contained a similar proportion of dyads and triads (Hispanic 88.2%, Black 88.9%), while the Black caregiving network included a slightly larger proportion of isolates (Hispanic 0.8%, Black 4.0%). This study provides useful baseline information on the composition of existing large groups and small groups. In addition, this work provides useful guidance for future recruitment strategies and the design of social support interventions regarding emotional needs for Hispanic and Black dementia caregivers.
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Demencia , Medios de Comunicación Sociales , Hispánicos o Latinos , Humanos , Análisis de Redes Sociales , Red SocialRESUMEN
Importance: Adults who belong to racial/ethnic minority groups are more likely than White adults to receive a diagnosis of chronic disease in the United States. Objective: To evaluate which health indicators have improved or become worse among Black and Hispanic middle-aged and older adults since the Minority Health and Health Disparities Research and Education Act of 2000. Design, Setting, and Participants: In this repeated cross-sectional study, a total of 4â¯856â¯326 records were extracted from the Behavioral Risk Factor Surveillance System from January 1999 through December 2018 of persons who self-identified as Black (non-Hispanic), Hispanic (non-White), or White and who were 45 years or older. Exposure: The 1999 legislation to reduce racial/ethnic health disparities. Main Outcomes and Measures: Poor health indicators and disparities including major chronic diseases, physical inactivity, uninsured status, and overall poor health. Results: Among the 4â¯856â¯326 participants (2â¯958â¯041 [60.9%] women; mean [SD] age, 60.4 [11.8] years), Black adults showed an overall decrease indicating improvement in uninsured status (ß = -0.40%; P < .001) and physical inactivity (ß = -0.29%; P < .001), while they showed an overall increase indicating deterioration in hypertension (ß = 0.88%; P < .001), diabetes (ß = 0.52%; P < .001), asthma (ß = 0.25%; P < .001), and stroke (ß = 0.15%; P < .001) during the last 20 years. The Black-White gap (ie, the change in ß between groups) showed improvement (2 trend lines converging) in uninsured status (-0.20%; P < .001) and physical inactivity (-0.29%; P < .001), while the Black-White gap worsened (2 trend lines diverging) in diabetes (0.14%; P < .001), hypertension (0.15%; P < .001), coronary heart disease (0.07%; P < .001), stroke (0.07%; P < .001), and asthma (0.11%; P < .001). Hispanic adults showed improvement in physical inactivity (ß = -0.28%; P = .02) and perceived poor health (ß = -0.22%; P = .001), while they showed overall deterioration in hypertension (ß = 0.79%; P < .001) and diabetes (ß = 0.50%; P < .001). The Hispanic-White gap showed improvement in coronary heart disease (-0.15%; P < .001), stroke (-0.04%; P < .001), kidney disease (-0.06%; P < .001), asthma (-0.06%; P = .02), arthritis (-0.26%; P < .001), depression (-0.23%; P < .001), and physical inactivity (-0.10%; P = .001), while the Hispanic-White gap worsened in diabetes (0.15%; P < .001), hypertension (0.05%; P = .03), and uninsured status (0.09%; P < .001). Conclusions and Relevance: This study suggests that Black-White disparities increased in diabetes, hypertension, and asthma, while Hispanic-White disparities remained in diabetes, hypertension, and uninsured status.
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Asma/etnología , Diabetes Mellitus/etnología , Disparidades en el Estado de Salud , Hipertensión/etnología , Pacientes no Asegurados/etnología , Salud de las Minorías/tendencias , Conducta Sedentaria/etnología , Negro o Afroamericano/estadística & datos numéricos , Anciano , Artritis/etnología , Enfermedad Coronaria/etnología , Estudios Transversales , Depresión/etnología , Femenino , Indicadores de Salud , Hispánicos o Latinos/estadística & datos numéricos , Humanos , Seguro de Salud/tendencias , Enfermedades Renales/etnología , Masculino , Persona de Mediana Edad , Accidente Cerebrovascular/etnología , Estados Unidos/epidemiología , Población Blanca/estadística & datos numéricosRESUMEN
We applied social network analysis (SNA) to Tweets mentioning cannabis or opioid-related terms to publicly available COVID-19 related Tweets collected from Jan 21st to May 3rd, 2020 (n= 2,558,474 Tweets). We randomly extracted 16,154 Tweets mentioning cannabis and 4,670 Tweets mentioning opioids from the COVID-19 Tweet corpora for our analysis. The cannabis related Tweets created by 6,144 users were disseminated to 280,042,783 users and retweeted 11 times the number of original messages while opioid-related Tweets created by 3,412 users were disseminated to smaller number of users. The opioids Twitter network showed more cohesive online group activities and a cleaner online environment with less disinformation. The cannabis Twitter network showed a less desirable online environment with more disinformation (false information to mislead the public) and stakeholders lacking strong science knowledge. Application of SNA to Tweets provides insights for future online-based drug abuse research during the outbreak.
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Betacoronavirus , Cannabis , Infecciones por Coronavirus , Pandemias , Neumonía Viral , Medios de Comunicación Sociales , Trastornos Relacionados con Sustancias , Analgésicos Opioides , COVID-19 , Humanos , SARS-CoV-2 , Red SocialRESUMEN
We randomly extracted publicly available Tweets mentioning COVID-19 related terms (n=2,558,474 Tweets) from Tweet corpora collected daily using an API from Jan 21st to May 3rd, 2020. We applied a clustering algorithm to publicly available Tweets authored by African Americans (n=1,763) to detect topics and sentiment applying natural language processing (NLP). We visualized fifteen topics (four themes) using network diagrams (Newman modularity 0.74). Compared to the COVID-19 related Tweets authored by others, positive sentiments, cohesively encouraging online discussions (e.g., Black strong 27.1%, growing up Blacks 22.8%, support Black business 17.0%, how to build resilience 7.8%), and COVID-19 prevention behaviors (e.g., masks 4.7%, encouraging social distancing 9.4%) were uniquely observed in African American Twitter communities. Application of topic modeling techniques to streaming social media Twitter provides the foundation for research team insights regarding information and future virtual based intervention and social media based health disparity research for COVID-19.
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Betacoronavirus , Infecciones por Coronavirus , Pandemias , Neumonía Viral , COVID-19 , Humanos , SARS-CoV-2 , Medios de Comunicación SocialesRESUMEN
We applied artificial intelligence techniques to build correlate models that predict general poor health in a national sample of caregivers with mild cognitive impairment (MCI). Our application of deep learning identified age, duration of caregiving, amount of alcohol intake, weight, myocardial infarction (MI) and frequency of MCI symptoms for Blacks and Hispanics whereas frequency of MCI symptoms, income, weight, coronary heart disease (CHD), age, and use of e-cigarette for the others as the strongest correlates of poor health among 81 variables entered. The application of artificial intelligence efficiently provided intervention strategies for Black and Hispanic caregivers with MCI.
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Disfunción Cognitiva , Inteligencia Artificial , Cuidadores , Sistemas Electrónicos de Liberación de Nicotina , Hispánicos o Latinos , Humanos , AutoinformeRESUMEN
The aim of this study was to investigate the effects of dental students' faculty group leader in clinic, intended postgraduate training, and clinic schedule on their clinical performance. This retrospective study used de-identified transcript data from the Columbia University College of Dental Medicine Classes of 2013, 2014, and 2015, a total of 238 students. The impact factors analyzed were the assigned faculty member who served as clinical group leader and mentor; area of students' intended postgraduate training; and variations in timing of students' summer clinic assignments and vacations. Clinical performance, consistent with the school's graduation criteria, was measured with summative assessments (completion of competencies); completion of care for patients assigned (case completions); and overall patient encounter rate. The results showed that group leader assignment correlated with significant differences among students in completion of cases (p=0.001), competencies completed (p<0.001), and patient encounter rate (p=0.018). Students who intended to pursue general practice residencies and prosthodontics specialty training completed fewer cases than students pursuing other types of postgraduate training (p<0.001). Students who had full-time clinic in June and vacation later in the summer of their third- to fourth-year transition completed more cases (p<0.001), completed more competencies (p=0.008), and had more patient visits (p=0.012) than those who had full-time clinic later in the summer. There were significant correlations among case completions, completion of competencies, and patient encounter rate. Overall, this study found that the students' intended postgraduate training, clinic schedules, and faculty mentors influenced their progress in clinical training and should be taken into consideration in student evaluation and patient care.
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Facultades de Odontología , Estudiantes de Odontología , Competencia Clínica , Educación en Odontología , Docentes de Odontología , Humanos , Estudios RetrospectivosRESUMEN
BACKGROUND/OBJECTIVE: Hispanics are about 1.5 times as likely as non-Hispanic Whites to experience Alzheimer's disease and related dementias (AD/ADRD). Eight percent of AD/ADRD caregivers are Hispanics. The purpose of this article is to provide a methodological case study of using data mining methods and the Twitter platform to inform online self-management and social support intervention design and evaluation for Hispanic AD/ADRD caregivers. It will enable other researchers to replicate the methods for their phenomena of interest. METHOD: We extracted an analytic corpus of 317,658 English and Spanish tweets, applied content mining (topic models) and network structure analysis (macro-, meso-, and micro-levels) methods, and created visualizations of results. RESULTS: The topic models showed differences in content between English and Spanish tweet corpora and between years analyzed. Our methods detected significant structural changes between years including increases in network size and subgroups, decrease in proportion of isolates, and increase in proportion of triads of the balanced communication type. DISCUSSION/CONCLUSION: Each analysis revealed key lessons that informed the design and/or evaluation of online self-management and social support interventions for Hispanic AD/ADRD caregivers. These lessons are relevant to others wishing to use Twitter to characterize a particular phenomenon or as an intervention platform.