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1.
In. Soeiro, Alexandre de Matos; Leal, Tatiana de Carvalho Andreucci Torres; Accorsi, Tarso Augusto Duenhas; Gualandro, Danielle Menosi; Oliveira Junior, Múcio Tavares de; Caramelli, Bruno; Kalil Filho, Roberto. Manual da residência em cardiologia / Manual residence in cardiology. Santana de Parnaíba, Manole, 2 ed; 2022. p.788-792, tab.
Monography in Portuguese | LILACS | ID: biblio-1353341
2.
Prensa méd. argent ; 107(6): 299-306, 20210000. tab, fig
Article in English | LILACS, BINACIS | ID: biblio-1359089

ABSTRACT

Introducción. El consumo de alcohol daña la mayoría de los órganos y sistemas de nuestro organismo, con un efecto nocivo sobre la diabetes tipo 2. En nuestro país, el consumo de alcohol es tolerado y socialmente bien considerado, lo que provoca que una parte importante de la población tenga una ingesta excesiva de alcohol. Por tanto, quisimos evaluar el efecto de la ingesta excesiva de alcohol en la población trabajadora y su efecto sobre el riesgo de desarrollar diabetes tipo 2. Métodos. Estudio descriptivo y transversal en 55.147 trabajadores españoles en el que se evaluó el efecto del consumo excesivo de alcohol sobre el riesgo de desarrollar diabetes tipo 2. El riesgo de diabetes se evaluó con las escalas Findrisk y QDScore. El consumo de alcohol se evalúa con la unidad de bebida estándar, equivalente a 10 g de alcohol. Se considera consumo excesivo cuando se superan semanalmente 35 unidades de bebida estándar en hombres y 20 en mujeres. Resultados. El consumo excesivo de alcohol en comparación con no beber, beber poco o moderadamente aumenta el riesgo de diabetes tipo 2 en ambas escalas de riesgo. La razón de probabilidades es 12,22 (IC 95 11,51-12,99) para la escala Findrisk y 13,36 (IC 95% 12,04-14,69) para el riesgo relativo con QDScore. Conclusión. El consumo excesivo de alcohol aumenta el riesgo de diabetes tipo 2 con las escalas Findrisk y QDScore en la población laboral española


Introduction. Alcohol consumption damages most of the organs and systems of our organism, with a harmful effect on type 2 diabetes. In our country, alcohol consumption is tolerated and socially well regarded, which causes an important part of the population to have an excessive alcohol intake. Therefore, we want to evaluate the effect of excessive alcohol intake in the working population and its effect on the risk of developing type 2 diabetes. Methods. Descriptive and cross-sectional study in 55,147 Spanish workers in which the effect of excessive alcohol consumption on the risk of developing type 2 diabetes was assessed. Diabetes risk was assessed with the Findrisk and QDScore scales. Alcohol consumption is assessed with the standard drinking unit, equivalent to 10g of alcohol. Excessive consumption is considered when 35 standard drinking unit in men and 20 in women are exceeded weekly. Results. Heavy drinking compared to no, low or moderate drinking increases the risk of type 2 diabetes on both risk scales. The Odds ratio is 12.22 (CI 95 11.51-12.99) for the Findrisk scale and 13.36 (CI 95% 12.04-14.69) for the relative risk with QDScore. Conclusion. Excessive alcohol consumption increases the risk of type 2 diabetes with the Findrisk and QDScore scales in the Spanish working population


Subject(s)
Humans , Alcohol Drinking/adverse effects , Risk Assessment , Diabetes Mellitus/diagnosis , Diabetes Mellitus, Type 2/diagnosis , Binge Drinking/complications , Occupational Groups
3.
Rev. cuba. med. gen. integr ; 37(2): e1410, 2021. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1352008

ABSTRACT

Introducción: La calidad de vida relacionada con la salud, como indicador positivo que evalúa el proceso salud-enfermedad, ha ido ganando en uso, a partir del cambio en los patrones de morbilidad, generado por el envejecimiento demográfico. Objetivo: Caracterizar la calidad de vida relacionada con la salud desde la perspectiva nomotética y su relación con variables de personas y tiempo. Métodos: Se realizó un estudio descriptivo-transversal en 200 adultos con diagnóstico de diabetes mellitus, hipertensión arterial o ambas, atendidos en el centro Daniel Álvarez, de Loja quienes cumplían varios criterios. Se calcularon medias y desviaciones típicas, porcentajes, y pruebas de significación como ANOVA, comparación de medias en muestras independientes y Análisis de Tablas de Contingencia, a través de la Razón de Verosimilitud, con un nivel de significación del 5 por ciento. Resultados: El puntaje promedio de la calidad de vida fue de 2,90, sin asociaciones significativas con las variables investigadas (p > 0,05). Las dimensiones física (3,30) y relaciones sociales (3,09) puntuaron por encima, mientras la psicológica (2,71) y el ambiente (2,70) lo hicieron por debajo. Solo la escolaridad, para la dimensión psicológica (p = 0,03) se asoció de manera significativa al puntaje alcanzado por esta. Conclusiones: La calidad de vida relacionada con la salud global, desde una perspectiva nomotética, en los adultos objeto de estudio, mostró un nivel aceptable, no asociada a ninguna de las variables en estudio. Los dominios psicológico y ambiente obtuvieron el peor puntaje; en tanto el físico y las relaciones sociales exhibieron niveles superiores al global(AU)


Introduction: Health-related quality of life, as a positive indicator that evaluates the health-disease process, has been gaining more use, due to the change in morbidity patterns, generated by demographic aging. Objective: To characterize health-related quality of life from the nomothetic perspective and its relationship with variables of people and time. Methods: A descriptive and cross-sectional study was carried out with 200 adults with a diagnosis of diabetes mellitus, hypertension, or both, cared for at Daniel Álvarez center, in Loja, who met several criteria. Means and standard deviations were calculated, together with percentages. Significance tests such as ANOVA, comparison of means in independent samples, and analysis of contingency tables were carried out, using likelihood ratio, with a significance level of 5 percent. Results: The average score for quality of life was 2.90, without significant associations with the variables investigated (0.05). The physical (3.30) and social relations (3.09) dimensions scored higher, while the psychological (2.71) and the environmental (2.70) scored lower. Only schooling, for the psychological dimension (P=0.03), was significantly associated with its achieved score. Conclusions: The global health-related quality of life in the adults under study, from a nomothetic perspective, showed an acceptable level, not associated with any of the variables analyzed. The psychological and environmental domains obtained the worst scores, while the physical and social relations dimensions exhibited levels higher than the global one(AU)


Subject(s)
Humans , Male , Female , Quality of Life , Diabetes Mellitus/diagnosis , Noncommunicable Diseases/epidemiology , Hypertension/diagnosis , Epidemiology, Descriptive , Cross-Sectional Studies
4.
Ciênc. Saúde Colet ; 26(4): 1207-1219, abr. 2021. tab
Article in English, Portuguese | LILACS | ID: biblio-1285919

ABSTRACT

Resumo O objetivo deste artigo é comparar as prevalências autorreferidas e medidas por exames laboratoriais, assim como a ocorrência de valores de falsos positivos e negativos, para diabetes, doença renal crônica e hipercolesterolemia. Foram utilizadas informações da entrevista e exames laboratoriais da Pesquisa Nacional de Saúde (2013, 2014-2015). Foram calculadas a sensibilidade e a especificidade, segundo sexo, idade, escolaridade, ter plano de saúde e tempo desde a última consulta médica. Por meio de regressão logística, foram analisados fatores associados à ocorrência de falsos positivos e falsos negativos. A sensibilidade foi mais elevada para o diabetes e entre os idosos e os que tiveram consulta médica mais recentemente. A especificidade foi alta para todas as doenças, com melhor desempenho entre os jovens, os com alta escolaridade e os que consultaram há mais de um ano. As chances de falsos positivos e falsos negativos diminuíram com a escolaridade e aumentaram com a idade. A sensibilidade baixa indica que as prevalências podem ser mais elevadas que as medidas autoreferidas apontam.


Abstract This paper aims to compare the self-reported prevalence measured by laboratory tests and the false positive and negative values for diabetes, chronic kidney disease, and hypercholesterolemia. We used information from the interview and laboratory tests of the National Health Survey (2013, 2014-2015). Sensitivity and specificity were calculated by gender, age, schooling, having health insurance, and time since the last medical visit. We used logistic regression to analyze associated factors with false positives and negatives. Sensitivity was higher for diabetes and among older adults and those who had a medical visit more recently. Specificity was high for all diseases, with better performance among younger people, those with high schooling, and a visit more than one year ago. The likelihood of false positives and negatives decreased with schooling and increased with age. Low sensitivity suggests that prevalence might be higher than indicated by self-reported measures.


Subject(s)
Humans , Aged , Diabetes Mellitus/diagnosis , Diabetes Mellitus/epidemiology , Renal Insufficiency, Chronic/diagnosis , Renal Insufficiency, Chronic/epidemiology , Hypercholesterolemia/diagnosis , Hypercholesterolemia/epidemiology , Self Report , Laboratories
5.
Rev. Asoc. Odontol. Argent ; 109(1): 64-72, ene.-abr. 2021. tab
Article in Spanish | LILACS | ID: biblio-1281783

ABSTRACT

La diabetes mellitus es una enfermedad metabólica caracterizada por altos niveles de glucosa en sangre y defectos en la producción y/o la acción de la insulina. La hiperglucemia crónica puede derivar en complicaciones metabólicas y vasculares como micro- y macroangiopatías y alteraciones en el metabolismo de lípidos y proteínas. Los pacientes diabéticos mal controlados o no controlados presentan signos y síntomas evidenciables a nivel bucal. En el mundo, alrededor del 8,8% de los adultos de entre 20 y 79 años padecen este trastorno endócrino, y se estima que para el año 2045 unos 629 millones de personas de este rango etario tendrán diabetes. Por ello, es fundamental que el odontólogo se encuentre familiarizado con el manejo médico de estos pacientes, a fin de estar preparado para brindarles un tratamiento adecuado y responder a las emergencias médicas que se presenten durante su atención. En esta revisión se emplearon resultados extraídos manualmente de artículos indexados en las bases de datos MEDLINE y EBSCO que responden a la búsqueda de los términos diabetes mellitus, dental management, oral surgery y HbA1c, con el objetivo de describir el manejo médico-odontológico del paciente diabético hasta la fecha (AU)


Diabetes Mellitus is a metabolic disease characterized by high blood glucose levels and defects in the production and/or the use of insulin. Chronic hyperglycemia can lead to metabolic and vascular complications. Vascular complications include micro and macroangiopathies. The metabolic disorders are: alterations of lipid and protein metabolism. Patients with poorly controlled or uncontrolled diabetes present symptoms that are evident in the oral cavity. Around 8.8% of adults between 20-79 years old, worldwide, have this endocrine disorder and it is estimated that by 2045, 629 million people in this age group, will have diabetes. Therefore, it is essential for dentists to be familiar with the medical management of these patients, in order to provide adequate treatment and eventual management of medical emergencies that may occur during dental treatment. The present review used data extracted manually from articles indexed in the MEDLINE and EBSCO databases, using the terms: Diabetes mellitus, Dental Management, Oral Surgery and HbA1c. The following article aims to describe the medical/dental management of the diabetic patient updated to date (AU)


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Dental Care for Chronically Ill/methods , Diabetes Complications , Diabetes Mellitus/pathology , Surgery, Oral/methods , Glycated Hemoglobin A , Databases, Bibliographic , Diabetes Mellitus/diagnosis , Diabetes Mellitus/epidemiology , Hyperglycemia/complications
6.
Rev. urug. cardiol ; 36(1): e36104, abr. 2021. tab
Article in Spanish | LILACS, BNUY, UY-BNMED | ID: biblio-1252413

ABSTRACT

La diabetes mellitus es una de las principales causas de morbilidad y mortalidad a nivel mundial. Este grupo de pacientes generalmente representa una población con alto o muy alto riesgo cardiovascular, razón por la cual se realiza una estratificación precoz del riesgo, buscando enfocarse objetivamente en el abordaje farmacológico y no farmacológico con una estrategia intensiva. La enfermedad cardiovascular representa la principal causa de mortalidad, pero en los últimos años se han producido avances en la terapéutica que han demostrado reducir los eventos cardiovasculares mayores. Este artículo revisa la interacción entre diabetes, enfermedades cardiovasculares y su tratamiento.


Diabetes mellitus is one of the main causes of morbidity and mortality worldwide. This group of patients generally represents a population with high or very high cardiovascular risk, that is the reason for an early stratification of risk, seeking to objectively focus on pharmacological and non-pharmacological approach with an intensive strategy. Cardiovascular disease represents the main cause of mortality, but in recent years there have been advances in therapeutics that have been shown to reduce major cardiovascular events. This article reviews the interaction between diabetes, cardiovascular diseases and their treatment.


A diabetes mellitus é uma das principais causas de morbimortalidade em todo o mundo. Esse grupo de pacientes geralmente representa uma população com alto ou muito alto risco cardiovascular, razão pela qual se estratifica precocemente o risco, buscando enfocar objetivamente a abordagem farmacológica e não farmacológica com estratégia intensiva. A doença cardiovascular representa a principal causa de mortalidade, mas nos últimos anos houve avanços na terapêutica que mostraram reduzir os eventos cardiovasculares maiores. Este artigo analisa a interação entre diabetes, doenças cardiovasculares e seu tratamento.


Subject(s)
Humans , Cardiovascular Diseases/diagnosis , Cardiovascular Diseases/drug therapy , Diabetes Complications , Diabetes Mellitus/diagnosis , Diabetes Mellitus/drug therapy , Hypoglycemic Agents/adverse effects , Biomarkers , Cardiovascular Diseases/etiology , Risk Assessment , Diabetes Mellitus/epidemiology
7.
Rev. cuba. enferm ; 37(1): e3536, 2021. tab
Article in Spanish | LILACS, BDENF, CUMED | ID: biblio-1341376

ABSTRACT

Introducción: La diabetes mellitus es una enfermedad metabólica que afecta a la población y requiere la evaluación de la calidad de vida para la formulación de estrategias de atención específicas y así minimizar o prevenir su deterioro. Objetivo: Evaluar la calidad de vida de personas con diabetes mellitus monitoreadas por la Unidad Básica de Salud. Métodos: Estudio transversal realizado con 82 diabéticos en una Unidad Básica de Salud. Se utilizaron cuestionarios que contenían variables sociodemográficas y clínicas y las áreas clínica y Problem Areas in Diabetes para la evaluación evaluar de la calidad de vida. En el análisis de datos, se utilizaron la prueba de Kruskal-Wallis, la prueba U de Mann-Whitney, la prueba t de Student y el analysis of variance. La mayoría de los participantes fueron mujeres, ancianas, casadas, con educación primaria completa, morenas, jubiladas, con su propio hogar, con un ingreso familiar de hasta un salario mínimo, diabéticos tipo 2, no fumadores, que usan antidiabéticos orales como una forma de tratamiento, sedentarios, no alcohólico, con dos comorbilidades asociadas a diabetes y entre seis y 10 años de diagnóstico. La puntuación total mostró un promedio de 32,36, lo que indica una buena calidad de vida para la mayoría de los participantes, y aquellos que sufren un impacto negativo presentan el factor emocional más afectado. Conclusión: Los datos obtenidos con este estudio permitirán la planificación de acciones específicas dirigidas a esta población para promover una mejor adherencia a las prácticas que influyen positivamente en la calidad de vida(AU)


Introdução: O Diabetes mellitus é uma doença metabólica que acomete a população, sendo necessária a avaliação da qualidade de vida para a formulação de estratégias de cuidado específicas para minimizar ou prevenir o seu comprometimento. Objetivo: Avaliar a qualidade de vida de pessoas com Diabetes Mellitus acompanhados pela Unidade Básica de Saúde. Métodos: Estudo transversal realizado com 82 diabéticos em uma Unidade Básica de Saúde. Utilizou- se questionários contendo variáveis sociodemográficas e clínicas e o Problem Areas in Diabetes para avaliação da qualidade de vida. Na análise dos dados, utilizaram-se os testes Kruskal-Wallis, U de Mann-Whitney, teste t de Student e Analysis of variance. Resultados: A maioria dos participantes são mulheres, idosas, casadas, com ensino fundamental completo, pardas, aposentadas, com casa própria, com renda familiar de até um salário mínimo, diabéticos tipo 2, não fumantes, que utilizam os antidiabéticos orais como forma de tratamento, sedentários, não etilistas, com duas comorbidades associadas ao diabetes e entre seis a 10 anos de diagnóstico. O escore total apresentou média de 32,36 , indicando boa qualidade de vida para a maioria dos participantes, e aqueles que sofrem impacto negativo apresentam o fator emocional como domínio mais acometido. Conclusão: Os dados obtidos com este estudo possibilitará o planejamento de ações específicas voltadas a essa população de modo a promover melhor adesão a práticas que influenciem positivamente na qualidade de vida(AU)


Introduction: Diabetes mellitus is a metabolic disease that affects population health and requires quality of life assessment to formulate specific care strategies to minimize or prevent its deterioration. Objective: To assess the quality of life of people with diabetes mellitus monitored by the basic health unit. Methods: Cross-sectional study carried out with 82 diabetic patients in a basic health unit. Questionnaires containing sociodemographic and clinical variables, as well as the problem areas in diabetes, were used to assess quality of life. In the data analysis, the Kruskal-Wallis test, the Mann-Whitney U test, the Student's t test and variance analysis were used. Results: Most of the participants were women, elderlies and had black skin. They were nonsmokers and nonalcoholic patients, had completed primary education and were retired. They had their own homes and a family income of up to a minimum wage. They had type 2 diabetes, apart from two comorbidities associated with diabetes, and between six and ten years of diagnosis. They used oral antidiabetics as a sedentary form of treatment. The total score showed an average of 32.36, which indicates a good quality of life for most of the participants, while those who suffered a negative impact had the emotional factor as the most affected domain. Conclusion: The data obtained from this study will allow planning specific actions targeted at this population to promote better adherence to practices that positively influence quality of life(AU)


Subject(s)
Humans , Quality of Life , Health Strategies , Diabetes Mellitus/diagnosis , Cross-Sectional Studies , Data Analysis , Metabolic Diseases/etiology
8.
Arq. ciências saúde UNIPAR ; 25(1): 43-51, jan-abr. 2021.
Article in Portuguese | LILACS | ID: biblio-1151409

ABSTRACT

Introdução: Usuários do sistema de saúde com doenças crônicas não transmissíveis devem estar em acompanhamento constante para evitar complicações em seu estado de saúde. Objetivo: Analisar os indicadores laboratoriais de saúde em usuários de uma Unidade Básica de Saúde com e sem o diagnóstico para a diabetes e hipertensão. Métodos: A amostra foi de 231 usuários de uma unidade básica de saúde da cidade de Santarém-PA, maiores de idade, que foram agrupados em pacientes com DM/HAS (DM/HAS; n=144), e sem o diagnóstico para DM/HAS (AUS; n=87). As coletas envolveram informações socioeconômicas, clínicas e laboratoriais. Os dados foram tratados com estatística descritiva e inferencial, adotando-se p<0.05. Resultados: Tanto no DM/HAS como no AUS predominou o sexo feminino, estado civil casado, com vínculo empregatício, cor de pele parda, com 4-7 anos de estudo, renda de 1-2 salários, não tabagistas, não etilista e faixa etária de 38-77 anos. A HAS foi a doença mais presente de forma geral, bem como por sexo. Identificou-se no DM/HAS valores menores para a taxa de filtração glomerular (TFG) e maiores valores para a glicemia, triglicerídeos, colesterol total, LDL-c e não HDL-c. Conclusão: De acordo com a proposta desenvolvida, destaca-se que os usuários com DM/HAS apresentam associação positiva para valores alterados de glicemia, colesterol total, não HDL-c, triglicerídeos, TFG e para a presença da síndrome metabólica e risco cardiovascular moderado/alto.


Introduction: Users of the health system with chronic non-communicable diseases must be constantly monitored to avoid complications in their health status. Objective: Analyze laboratory health indicators in users of a Basic Health Unit with and without a diagnosis for diabetes and hypertension. Methods: The sample consisted of 231 users of a basic health unit in the city of Santarém-PA, all of them of age, grouped into patients with DM/SAH (DM/SAH; n=144), and without the diagnosis for DM/SAH (ABS; n=87). The collections involved socioeconomic, clinical, and laboratory information. The data were treated with descriptive and inferential statistics, adopting p <0.05. Results: In both DM/SAH and ABS groups, there was a predominance of female individuals, married status, employed, brown skin color, with 4-7 years of study, income of 1-2 salaries, non-smokers, non-alcoholic drinkers, and aged between 38-77 years. SAH was the most common disease in general, as well as when analyzing by gender. Lower values for the glomerular filtration rate (GFR) were identified in the DM/SAH and higher values for the glycemia, triglycerides, total cholesterol, LDL-c, and non-HDL-c. Conclusion: According to the proposal of this paper, it is noteworthy that users with DM/SAH have a positive association for altered values of blood glucose, total cholesterol, non-HDL-c, triglycerides, GFR, and for the presence of metabolic syndrome and moderate/high cardiovascular risk.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Health Evaluation/statistics & numerical data , Health Centers , Health Status Indicators , Tobacco Use Disorder/complications , Triglycerides/blood , Blood Glucose , Alcohol Drinking/adverse effects , Cardiovascular Diseases/diagnosis , Cholesterol/blood , Chronic Disease/nursing , Metabolic Syndrome/diagnosis , Diabetes Mellitus/diagnosis , Noncommunicable Diseases/prevention & control , Glomerular Filtration Rate , Hypertension/diagnosis , Cholesterol, HDL , Cholesterol, LDL/blood
9.
Rev. chil. endocrinol. diabetes ; 14(4): 171-177, 2021. tab
Article in Spanish | LILACS | ID: biblio-1348218

ABSTRACT

Los avances en el campo de la fibrosis quística han aumentado la esperanza de vida de estos pacientes, por lo que cada vez es más prevalente la Diabetes Relacionada con la Fibrosis Quística (DRFQ) y sus complicaciones. La DRFQ se asocia a mayor morbimortalidad, deterioro de la función pulmonar y del estado nutricional. Por lo mismo, el manejo óptimo de esta patología depende de un diagnóstico precoz, tratamiento individualizado y vigilancia de las complicaciones diabéticas. El screening de DRFQ debe realizarse anualmente a partir de los 10 años, mediante una Prueba de Tolerancia a la Glucosa Oral (PTGO), lo cual permite el diagnóstico. El manejo de esta patología tiene por objetivo estabilizar y mejorar la función pulmonar y el estado nutricional y metabólico de los pacientes. Actualmente, la insulina es el tratamiento farmacológico de elección para controlar la hiperglicemia y el esquema de uso debe ser individualizado para cada persona. En caso de enfermedades agudas pueden existir mayores requerimientos de insulina. Además, se deben tener consideraciones especiales en cuanto a la dieta y la insuficiencia pancreática exocrina que presentan estos pacientes. Para la vigilancia de complicaciones microvasculares se debe realizar una monitorización anual a partir de los 5 años desde el diagnóstico de DRFQ. Debido a la complejidad de estos pacientes, para alcanzar el mejor cuidado posible se necesita un enfoque multidisciplinario con distintos profesionales de la salud coordinados, incluyendo en la toma de decisiones al paciente y su familia.


Advances made in the field of cystic fibrosis have increased the life expectancy of these patients, which is why Cystic Fibrosis-Related Diabetes (CFRD) and its complications are becoming more and more prevalent. CFRD is associated with increased morbidity and mortality, lower lung function and inadequate weight maintenance. Therefore, the optimal management of this pathology depends on an early diagnosis, individualized treatment and monitoring of diabetic complications. For CFRD, routine screening with an Oral Glucose Tolerance Test (OGTT) should be carried out yearly from the age of 10, which allows to diagnose it. The treatment goals in CFRD are to stabilize and improve lung function and obtain adequate weight gain. Currently, insulin is the pharmacological treatment of choice to control hyperglycemia and the insulin regimen must be personalized for each person. In acute illnesses, there may be higher insulin requirements. In addition, special considerations must be taken regarding diet and exocrine pancreatic insufficiency that these patients present. For the surveillance of microvascular complications, annual monitoring should be carried out 5 years after the diagnosis of CFRD. Due to the complexity of these patients, in order to achieve the best possible care, a multidisciplinary approach is needed with different coordinated health professionals, including the patients and their family in the decision-making process.


Subject(s)
Humans , Cystic Fibrosis/complications , Cystic Fibrosis/diagnosis , Cystic Fibrosis/therapy , Diabetes Mellitus/etiology , Diabetes Mellitus/therapy , Patient Care Team , Mass Screening , Cystic Fibrosis/physiopathology , Nutrition Therapy , Diabetes Mellitus/diagnosis , Diabetes Mellitus/physiopathology , Insulins/therapeutic use , Glucose Tolerance Test , Hypoglycemic Agents/therapeutic use
10.
In. Spósito García, Paola; García, Silvia. Manejo de la hiperglucemia en el paciente con diabetes mellitus. Montevideo, Oficina del Libro-FEFMUR, 2021. p.31-37.
Monography in Spanish | LILACS, BNUY, UY-BNMED | ID: biblio-1373128
12.
Arq. Ciênc. Vet. Zool. UNIPAR (Online) ; 23(1, cont.): e2309, 20200000. tab
Article in Portuguese | LILACS, VETINDEX | ID: biblio-1129312

ABSTRACT

A diabetes mellitus (DM) é uma doença comum na rotina veterinária, de caráter multifatorial, gerando graves consequências na saúde dos pacientes acometidos. O diagnóstico é possível por meio de manifestações clínicas apresentadas e da realização de exames laboratoriais complementares. Entre esses exames, estão a dosagem da glicose sérica e a urinálise, as quais trazem ao clínico diversas informações, que podem ser correlacionadas aos demais achados, tornando possível o diagnóstico conclusivo de DM. Dessa forma, o presente trabalho teve como objetivo avaliar as alterações urinárias e de glicemia em cães com DM. Para isto, foram analisados laudos de amostras urinárias e de glicose sérica de 15 animais, onde o diagnóstico foi conclusivo para DM. Verificou-se presença de glicosúria em 100% dos casos, sendo observado em 66,67% das amostras glicosúria maior que 1000 mg/dL e, em 33,33% amostras, de 500 mg/dL; a cetonúria esteve presente em 66,67 %; proteinúria em 66,67% e bacteriúria presente em 73,33 dos dados analisados. Já a hiperglicemia foi constatada em 13 pacientes (86,67%). Assim, conclui-se que a urinálise é um exame de suma importância para o estabelecimento do diagnóstico, da melhor terapêutica para cada caso e do prognóstico dos pacientes.(AU)


Diabetes mellitus (DM) is a common disease on the veterinary routine. It has a multifactorial character generating severe consequences on the health of the patient. It can be diagnosed by clinical manifestations and by making additional laboratory tests. These tests include the measurement of serum glucose and urinalysis, which provides the physician with additional information to be correlated with other findings, in order to reach a conclusive diagnosis of DM. Therefore, this study aimed at evaluating urinary and glycemic alterations in dogs with DM. It analyzed reports of urine and serum glucose samples from 15 animals with a conclusive diagnosis for DM. Glycosuria was present in 100% of the cases. In addition, it was also observed that in 66.67% of the samples, glycosuria was higher than 1000 mg/dL, and in 33.33%, it was 500 mg/dL. Ketonuria was present in 66.67% of the samples, while proteinuria was observed in 66.67%. Bacteriuria was present in 73.33% of the samples on the analyzed data. Hyperglycemia was observed in 13 of these patients (86.67%), and thus, it can be concluded that urinalysis is an extremely important test for diagnosis, to choose the best therapy for each case and prognosis of the patients.(AU)


Diabetes mellitus (DM) es una enfermedad común en la rutina veterinaria, con un carácter multifactorial, que genera graves consecuencias en la salud de los pacientes afectados. El diagnóstico es posible a través de las manifestaciones clínicas presentadas y mediante realización de pruebas de laboratorio complementarias. Entre esas pruebas, están la medición de la glucosa en suero y el análisis de orina, que brindan al médico informaciones diversas que pueden ser correlacionadas a otros hallazgos, lo que permite hacer un diagnóstico concluyente de DM. Por lo tanto, el presente estudio tuvo como objetivo evaluar las alteraciones urinarias y glucémicas en perros con DM. Para esto, se analizaron informes de muestras de glucosa en suero y orina de 15 animales, donde el diagnóstico fue concluyente para DM. La glucosuria estuvo presente en el 100% de los casos, observándose en el 66,67% de las muestras glucosuria mayor de 1000 mg / dL y, en el 33,33% de las muestras, de 500 mg / dL; la cetonuria estuvo presente en 66.67%; proteinuria en 66.67% y bacteriuria presente en 73.33 de los datos analizados. Se observó hiperglucemia en 13 de esos pacientes (86,67%). Por lo tanto, se concluye que el análisis de orina es una prueba extremadamente importante para establecer el diagnóstico, el mejor tratamiento para cada caso y el pronóstico de los pacientes.(AU)


Subject(s)
Animals , Dogs , Urine , Urinalysis , Diabetes Mellitus/diagnosis , Dogs/physiology , Ketosis/diagnosis
14.
Cienc. enferm. (En línea) ; 26: 6, 2020. tab
Article in Portuguese | LILACS, BDENF | ID: biblio-1124364

ABSTRACT

RESUMO Objetivo: Verificar a relação entre variações do clearance de creatinina (ClCr) e os fatores clínicos de pacientes internados em clínica médica. Material e Método: Estudo longitudinal, do tipo coorte prospectivo, quantitativo, realizado em um hospital público do Distrito Federal. 85 pacientes evoluíram com Lesão Renal Aguda (LRA), de acordo com a classificação Kidney Disease: Improving Glogal Guidelines (KDIGO). O acompanhamento foi até 1 mês pós-alta hospitalar. A gravidade dos pacientes foi medida através do Índice de Comorbidade de Charlson. Considerou-se significativo resultados com p ≤ 0,05. Resultados: 51,8% dos pacientes eram do sexo masculino. Entre as comorbidades se destacaram hipertensão arterial (70,6%), diabetes mellitus (57,6%) e as cardiopatias (52,9%). O tempo de permanência hospitalar (p= 0,001) e a idade (p= 0,05) estiveram associadas a pior função renal. Pacientes com ClCr ≤ 30 ml/min estiveram associados a uma maior taxa de mortalidade (p= 0,007). Conclusão: Idade avançada e maior tempo de internação hospitalar se associaram a piora da função renal (ClCr < 60 ml/min). Àqueles com severa piora da função renal (ClCr < 30 ml/min) apresentaram maior taxa mortalidade.


ABSTRACT Objective: To verify the relationship between variations in creatinine clearance (ClCr) and clinical factors in hospitalized patients in internal medicine. Material and Method: A prospective, quantitative, cohort study conducted at the medical clinic of a public hospital in Distrito Federal. 85 patients progressed with Acute Kidney Injury (AKI), according to the Kidney Disease Improving Glogal Guidelines (KDIGO) classification. Patients were followed-up to 1 month after hospital discharge. Patient severity was measured using the Charlson Comorbidity Index. Results with p ≤ 0.05 were considered significant. Results: 51.8% of the patients were male. Most common comorbidities were hypertension (70.6%), diabetes mellitus (57.6%) and heart disease (52.9%). The length of hospital stay (p = 0.001) and age (p = 0.05) were associated with worse renal function. Patients with CrCl ≤ 30 ml/min were associated with a higher mortality rate (p = 0.007). Conclusion: Older patients and longer hospital stay were associated with worsening renal function (CrCl < 60 ml/min). Those with severe worsening of renal function (CrCl < 30 ml/min) presented higher mortality rate.


RESUMEN Objetivo: Verificar la relación entre variaciones del clearance de creatinina (CLCr) y los factores clínicos de pacientes internados en medicina interna. Material y Método: Estudio longitudinal, del tipo cohorte prospectivo, cuantitativo, realizado en un hospital público del Distrito Federal. 85 pacientes evolucionaron con Lesión Renal Aguda (LRA), de acuerdo con la clasificación de las normas KDIGO (Kidney Disease: Improving Global Guidelines). El seguimiento fue hasta 1 mes post-alta hospitalaria. La gravedad de los pacientes fue medida a través del Índice de Comorbilidad de Charlson. Se consideraron significativos resultados con p ≤ 0,05. Resultados: 51,8% de los pacientes eran del sexo masculino. Entre las comorbilidades se destacaron hipertensión arterial (70,6%), diabetes mellitus (57,6%) y las cardiopatías (52,9%). El tiempo de permanencia hospitalaria (p = 0,001) y la edad (p = 0,05) estuvieron asociadas a la peor función renal. Los pacientes con ClCr ≤ 30 ml/min estuvieron asociados a una mayor tasa de mortalidad (p = 0,007). Conclusión: Edad avanzada y el mayor tiempo de internación hospitalaria se asociaron al empeoramiento de la función renal (ClCr < 60 ml/ min). Aquellos con severo empeoramiento de la función renal (CLCr < 30 ml/min) presentaron mayor tasa de mortalidad.


Subject(s)
Humans , Male , Female , Comorbidity , Acute Kidney Injury/complications , Diabetes Mellitus/diagnosis , Heart Diseases/diagnosis , Hypertension/diagnosis , Inpatients , Kidney Diseases/complications , Length of Stay
15.
Einstein (Säo Paulo) ; 18: eAO4483, 2020. tab
Article in English | LILACS | ID: biblio-1056068

ABSTRACT

ABSTRACT Objective To analyze the characteristics of patients with hypertension and/or diabetes mellitus from Primary Healthcare units. Methods This is a retrospective study, with data collected from December 2014 of patients with hypertension and/or diabetes from 13 Primary Healthcare units located in the Southern region of Sao Paulo (SP, Brazil). Patients were compared by sex, diagnosis and cardiovascular risk using student t test, one way analysis of variance (ANOVA), and Mann-Whitney, Kruskal-Wallis and χ2 tests. Results We evaluated 28,496 patients aged 20 years to 79 years (mean of 57.8 years). Most of patients were women (63.2%) and aged 50 years old or older (74.2%). The participation in the Programa Remédio em Casa (Medicine at Home Program) was higher among women (12.7%), and the proportions of hypertension, diabetes and both diseases were 68.0%, 7.9% and 24.1%, respectively. Patients with hypertension and diabetes had higher participation in Medicine at Home Program (13.3%), and those with diabetes only had higher participation in Programa de Automonitoramento Glicêmico (Self-Monitoring Glucose Program) (20.0%). The proportions of low, moderate, and high cardiovascular risk were 33.0%, 15.5%, and 51.5%, respectively. Conclusion The sample of this study consisted of patients who were mostly women, aged 50 years or older and diagnosed with hypertension. Almost a quarter of patients also had diabetes and approximately one third and half of them were classified as low and high cardiovascular risk.


RESUMO Objetivo Analisar as características de pacientes com hipertensão arterial e/ou diabetes mellitus de unidades de Atenção Primária à Saúde. Métodos Estudo retrospectivo, com dados de dezembro de 2014 de pacientes com hipertensão e/ou diabetes, de 13 unidades de Atenção Primária à Saúde localizadas na região sul da cidade de São Paulo (SP). Os pacientes foram comparados por sexo, diagnósticos e risco cardiovascular, por meio dos testes t de Student, análise de variância de um fator, Mann-Whitney, Kruskal-Wallis e χ2. Resultados Foram avaliados 28.496 pacientes, de 20 anos a 79 anos de idade (média de 57,8 anos), sendo a maioria do sexo feminino (63,2%) e com 50 anos ou mais de idade (74,2%). A participação no Programa Remédio em Casa foi maior no sexo feminino (12,7%) e as proporções de hipertensão, diabetes e de ambas as doenças foram de 68,0%, 7,9% e 24,1%, respectivamente. Os pacientes com hipertensão e diabetes apresentaram maior proporção de participação no Programa Remédio em Casa (13,3%) e aqueles com apenas diabetes apresentaram maior proporção de participação no Programa de Automonitoramento Glicêmico (20,0%). As proporções de risco cardiovascular baixo, moderado e alto foram de 33,0%, 15,5% e 51,5%, respectivamente. Conclusão A amostra deste estudo foi constituída por pacientes em sua maioria do sexo feminino, com 50 anos ou mais de idade e diagnóstico de hipertensão. Cerca de um quarto dos pacientes apresentava também diabetes e aproximadamente um terço e metade deles foram categorizados como risco cardiovascular baixo e alto, respectivamente.


Subject(s)
Humans , Male , Female , Adult , Aged , Young Adult , Primary Health Care/statistics & numerical data , Diabetes Mellitus/epidemiology , Hypertension/epidemiology , Brazil/epidemiology , Blood Glucose Self-Monitoring/statistics & numerical data , Cardiovascular Diseases/complications , Retrospective Studies , Risk Factors , Sex Distribution , Age Distribution , Diabetes Complications/diagnosis , Diabetes Complications/blood , Diabetes Complications/epidemiology , Diabetes Mellitus/diagnosis , Diabetes Mellitus/blood , Home Care Services/statistics & numerical data , Hypertension/complications , Hypertension/diagnosis , Middle Aged
16.
Article in English | AIM, AIM | ID: biblio-1257696

ABSTRACT

Background: Non-communicable diseases (NCDs) are a major public health concern with raised blood pressure and glucose emerging as leading causes of death and disability. Aim: This community-based demonstration project using community caregivers (CCGs) trained in screening for hypertension and diabetes aimed at improving early detection and linkage to care and management. Setting: The project was conducted in KwaZulu-Natal province. Methods: The CCGs were trained in NCD-related health education, promotion and screening for hypertension and diabetes using an accredited programme. The CCGs screened community members for hypertension and diabetes using three screening methods: door-to-door visits, community campaigns and workplaces. Results: Twenty-five CCGs received the accredited NCD training. A total of 10 832 community members were screened for hypertension and 6481 had their blood glucose measured. Of those screened, 29.7% and 4.4%, respectively, had raised blood pressure (≥ 140/90 mmHg) and blood glucose (≥ 11.0 mmol/L) who required referral to a primary healthcare facility. More than one in five (21.0%, n = 1448), of those with no previous hypertension diagnosis, were found to have raised blood pressure at screening, representing newly detected cases. Less than a third (28.5%) of patients referred to the facilities for raised blood pressure actually presented themselves for a facility assessment, of which 71.8% had their hypertension diagnosis confirmed and were advised to continue, adjust or initiate treatment. Similarly, 29.1% of patients referred to the facilities for raised blood glucose presented themselves at the facility, of which 71.4% received a confirmatory diabetes diagnosis. Conclusion: Community caregivers played an important role in early detection of raised blood pressure and raised blood glucose, and in referring patients to primary care


Subject(s)
Community Health Workers , Diabetes Mellitus , Diabetes Mellitus/diagnosis , Hypertension , Hypertension/statistics & numerical data , Noncommunicable Diseases , South Africa
19.
Rev. cuba. reumatol ; 21(3): e106, sept.-dic. 2019. tab, graf
Article in Spanish | LILACS, CUMED | ID: biblio-1093832

ABSTRACT

Introducción: la artritis reumatoide es una enfermedad sistémica, de etiología desconocida, caracterizada por provocar inflamación crónica, cursa con manifestaciones articulares, extrarticulares y comportamiento clínico variable. Objetivo: caracterizar los factores de riesgo para la aparición de aterosclerosis en pacientes con artritis reumatoide e identificar su relación con el tiempo de diagnóstico, actividad inflamatoria y tratamiento. Método: se realizó estudio descriptivo transversal, en pacientes con artritis reumatoide atendidos en el Centro de Reumatología del Hospital Docente Clínico Quirúrgico 10 de Octubre entre febrero 2016 y junio 2017. Resultados: la mayor frecuencia fue para el sexo femenino, el rango etario 45-54 años. Se observó placa ateromatosa en 37.2 por ciento y engrosamiento complejo íntima media en el 15.4 por ciento. Los factores de riesgo que mostraron asociación con la presencia de placa fueron: hipertrigliceridemia (p= 0.000), hipercolesterolemia (p= 0.000), Diabetes Mellitus (p= 0.027) y los niveles elevados de proteína C Reactiva (p= 0.003). Conclusiones: los factores de riesgo tradicionales que presentaron significación estadística fueron la hipercolesterolemia, hipertrigliceridemia y la Diabetes Mellitus. La presencia de más de un factor elevó la frecuencia de alteraciones en el eco doppler; existió asociación entre la elevación de los niveles de PCR y la presencia de alteraciones del eco doppler. Se constató en aquellos pacientes con alteraciones eco doppler carotídeo relación con el tiempo de evolución, actividad de la enfermedad y dosis acumulada de esteroides(AU)


Introduction: rheumatoid arthritis is a systemic disease, of unknown etiology, characterized by chronic inflammation; It presents with joint, extra-articular manifestations and variable clinical behavior. Objective: to characterize the risk factors for the appearance of atherosclerosis in patients with rheumatoid arthritis and to identify their relationship with the time of diagnosis, inflammatory activity and treatment. Method: a cross-sectional, descriptive study was conducted in patients with rheumatoid arthritis treated at the Rheumatology Center of the Surgical Clinical Teaching Hospital 10 de Octubre in the period between February 2016 and June 2017. Results: the highest frequency was for the female sex, the age range 45-54 years. Atheromatous plaque was observed in 37.2 percent and intimal complex thickening in 15.4 percent. The risk factors that showed association with the presence of plaque were: hypertriglyceridemia (p= 0.000), hypercholesterolemia (p= 0.000), Diabetes Mellitus (p= 0.027) and high levels of C-reactive protein (p= 0.003) Conclusions: the traditional risk factors that presented statistical significance were hypercholesterolemia, hypertriglyceridemia and Diabetes Mellitus. The presence of more than one traditional risk factor increased the frequency of alterations in Doppler echo; There was an association between the elevation of C-Reactive Protein levels and the presence of Doppler echo alterations. It was found in those patients with carotid echo Doppler alterations, relationship with the time of evolution, activity of the disease and cumulative dose of steroids(AU)


Subject(s)
Humans , Arthritis, Rheumatoid/complications , C-Reactive Protein/analysis , Hypertriglyceridemia/complications , Polymerase Chain Reaction/methods , Diabetes Mellitus/diagnosis , Atherosclerosis/complications , Hypercholesterolemia/complications , Epidemiology, Descriptive , Cross-Sectional Studies , Risk Factors
20.
Rev. medica electron ; 41(4): 899-913, jul.-ago. 2019. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1094097

ABSTRACT

RESUMEN Introducción: la diabetes mellitus es un trastorno metabólico caracterizado por hiperglucemia crónica con alteraciones en los carbohidratos, grasas y proteínas. Las tasas de morbimortalidad han aumentado al igual que la obesidad, constituye un problema de salud en el mundo, Cuba y la provincia de Matanzas. Objetivo: realizar una caracterización clínica epidemiológica de la diabetes mellitus tipo 2 en dos áreas de salud, conocer las variables e identificar las barreras para una posterior intervención. Materiales y métodos: se realizó un estudio epidemiológico descriptivo- transversal a 750 diabéticos tipo 2 mayores de 18 años en dos áreas de salud. Se realizaron encuestas, procesándose en el programa Epi-Info, obteniéndose la frecuencia de las variables, y las diferencias estadísticas significativas entre variables de las dos aéreas de salud, utilizándose el valor de p < 0,05 % y el Chi2. Resultados: el promedio de edad fue de 62,2 años, predominio del sexo femenino y color de la piel blanca. La hipertensión arterial y la obesidad fueron las enfermedades más asociadas, y el tabaquismo, la ingestión de bebidas alcohólicas y azucaradas, y la no realización de ejercicios físicos fueron los factores asociados más relevantes. Los medicamentos más utilizados fueron la glibenclamida y la metformina. Conclusiones: la diabetes mellitus es la primera causa de fracaso renal en el mundo occidental, siendo la insuficiencia renal una de las complicaciones crónicas más graves de esta enfermedad. Entre las principales causas de muerte de esta enfermedad son las complicaciones macrovasculares, manifestadas clínicamente como cardiopatía isquémica, insuficiencia cardíaca, la enfermedad vascular cerebral y la insuficiencia arterial periférica.


ABSTRACT Introduction: diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia with alterations in carbohydrates, fats and proteins. Morbi-mortality rates have increased as have done obesity, being a health problem in the world, Cuba and the province of Matanzas. Objective: to carry out clinical-epidemiological characterization of type 2 diabetes mellitus in two health areas, knowing the variables and identifying the barriers for a subsequent intervention. Materials and methods: a cross-sectional descriptive study was carried out in 750 type-2 diabetic patients over 18 years in two health areas. Surveys were made and processed in Epi-Info program, showing significant statistic differences among variables of both health areas; p < 0,05 % value and Chi2 were used. Results: the average age was 62.2 years, predominating female sex and white skin color. The most commonly associated diseases were arterial hypertension and obesity; smoking and drinking alcoholic and sugar-sweetened beverages and sedentary life were the most relevant associated factors. The most commonly used medications were glibenclamide and metformin. Conclusions: diabetes is the first cause of renal failure in the Western world, being renal insufficiency one of the most serious chronic complications of this disease. The main causes of death of this disease are macro vascular complications clinically manifested as ischemic heart disease, heart failure, cerebra-vascular disease and peripheral arterial insufficiency.


Subject(s)
Humans , Adult , Risk Factors , Glyburide/therapeutic use , Diabetes Mellitus/diagnosis , Diabetes Mellitus/etiology , Diabetes Mellitus/mortality , Diabetes Mellitus/drug therapy , Diabetes Mellitus/epidemiology , Metformin/therapeutic use , Tobacco Use Disorder/diagnosis , Epidemiology, Descriptive , Cross-Sectional Studies , Myocardial Ischemia/mortality , Stroke/mortality , Alcoholism/diagnosis , Renal Insufficiency/complications , Sedentary Behavior , Peripheral Arterial Disease/mortality , Heart Failure/mortality , Hypertension/diagnosis , Obesity/diagnosis
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